type 1 diabetes mellitus Disease Ontology Browser

Mouse Models

Human Disease Modeled: type 1 diabetes mellitus
Associated Mouse Gene: Cd38

Allelic Composition	Genetic Background	Reference	Phenotypes
Cd38tm1Lnd/Cd38tm1Lnd	NOD.129P2(B6)-Cd38^tm1Lnd/LtJ	J:108097	View

Mouse Models

Human Disease Modeled: type 1 diabetes mellitus
Associated Mouse Gene: Gad2

Allelic Composition	Genetic Background	Reference	Phenotypes
Gad2tm1Miya/Gad2tm1Miya	NOD.129P2-Gad2^tm1Miya	J:88785	View

Mouse Models

Human Disease Modeled: type 1 diabetes mellitus
Associated Mouse Gene: Il1r1

Allelic Composition	Genetic Background	Reference	Phenotypes
Il1r1tm1Roml/Il1r1tm1Roml	NOD.Cg-Il1r1^tm1Roml	J:87251	View

Mouse Models

Human Disease Modeled: type 1 diabetes mellitus
Associated Mouse Gene: Ins2

Allelic Composition	Genetic Background	Reference	Phenotypes
H2g7/H2g7 Ins2tm1Jja/Ins2tm1Jja Rag1tm1Mom/Rag1tm1Mom Tg(TcraBDC12-4.1)10Jos/0 Tg(TcrbBDC12-4.1)82Gse/0	involves: 129S2/SvPas * 129S7/SvEvBrd * C57BL/6 * FVB * NOD	J:111874	View
Ins2tm1Jja/Ins2tm1Jja	NOD.129S2-Ins2^tm1Jja	J:85309	View
Tg(H2-Ea-Ins2)1Wehi/0	NOD/ShiLtJWehi-Tg(H2-Ea-Ins2)1Wehi	J:100251	View
Ins2Akita/Ins2Akita	C.B6N-Ins2^Akita	J:198186	View
Ins2Akita/Ins2Akita Itga1tm1Gdnr/Itga1tm1Gdnr	C.Cg-Ins2^Akita Itga1^tm1Gdnr	J:198186	View
Ins1tm1Jja/Ins1tm1Jja Tg(Ins2*Y16A)1Ell/0	NOD.Cg-Ins1^tm1Jja Tg(Ins2*Y16A)1Ell	J:98583	View

NOT Models
No similarity to the expected human disease phenotype was found.

Allelic Composition	Genetic Background	Reference	Phenotypes
Ins1tm1Jja/Ins1tm1Jja Ins2tm1Jja/Ins2tm1Jja Tg(Ins2*Y16A)3Ell/0	NOD.Cg-Ins1^tm1Jja Ins2^tm1Jja Tg(Ins2*Y16A)3Ell	J:98583	View
Ins1tm1Jja/Ins1tm1Jja Ins2tm1Jja/Ins2tm1Jja Tg(Ins2*Y16A)1Ell/0	NOD.Cg-Ins1^tm1Jja Ins2^tm1Jja Tg(Ins2*Y16A)1Ell	J:98583	View
Ins1tm1Jja/Ins1tm1Jja	NOD.129S2-Ins1^tm1Jja	J:85309	View

Mouse Models

Human Disease Modeled: type 1 diabetes mellitus
Associated Mouse Gene: Ptprn2

Allelic Composition	Genetic Background	Reference	Phenotypes
Ptprn2tm1Aln/Ptprn2tm1Aln	involves: 129S4/SvJae * C57BL/6N * NOD/LtJ	J:81889	View

Mouse Models

Human Disease Modeled: type 1 diabetes mellitus

Allelic Composition	Genetic Background	Reference	Phenotypes
Prkdcscid/Prkdcscid Tg(INS-HBEGFL148SP149T)70Rin/0	C.BKa-Prkdc^scid Tg(INS-HBEGFL148SP149T)70Rin	J:204420	View

Mouse Models

Human Disease Modeled: type 1 diabetes mellitus

Allelic Composition	Genetic Background	Reference	Phenotypes
Casp1tm1Sesh/Casp1tm1Sesh Casp4del/Casp4del	NOD.129S2(B6)-Casp1^tm1Sesh Casp4^del/LtJ	J:87250	View

Mouse Models

Human Disease Modeled: type 1 diabetes mellitus
Associated Mouse Gene: Cdk4

Allelic Composition	Genetic Background	Reference	Phenotypes
Cdk4tm1Bbd/Cdk4tm1Bbd	involves: 129S1/Sv * 129X1/SvJ * ICR	J:54534	View

Mouse Models

Human Disease Modeled: type 1 diabetes mellitus
Associated Mouse Gene: E2f1

Allelic Composition	Genetic Background	Reference	Phenotypes
E2f1tm1Meg/E2f1tm1Meg	NOD.Cg-E2f1^tm1Meg	J:93708	View

Mouse Models

Human Disease Modeled: type 1 diabetes mellitus
Associated Mouse Gene: Fasl

Allelic Composition	Genetic Background	Reference	Phenotypes
Tg(Ins2-Fasl)24Ach/0	NOD-Tg(Ins2-Fasl)24Ach/J	J:78679	View
Tg(Ins2-Fas*I246N)1Ach/0 Tg(Ins2-Fasl)24Ach/0	NOD-Tg(Ins2-Fas*I246N)1Ach Tg(Ins2-Fasl)24Ach	J:81416	View
Faslpr/Faslpr Tg(Ins2-Fasl)24Ach/0	NOD.Cg-Fas^lpr Tg(Ins2-Fasl)24Ach	J:81416	View

Mouse Models

Human Disease Modeled: type 1 diabetes mellitus
Associated Mouse Gene: G6pc2

Allelic Composition	Genetic Background	Reference	Phenotypes
Tg(H2-Ea-G6pc2)69Tkay/?	NOD-Tg(H2-Ea-G6pc2)69Tkay	J:117352	View

Mouse Models

Human Disease Modeled: type 1 diabetes mellitus
Associated Mouse Gene: Ifng

Allelic Composition	Genetic Background	Reference	Phenotypes
Ifngtm1Ts/Ifngtm1Ts	NOD.129S7(B6)-Ifng^tm1Ts/DvsJ	J:72818	View
Ifngtm1Ts/Ifngtm1Ts	NOD.Cg-Ifng^tm1Ts Prkdc^scid	J:72818	View

Mouse Models

Human Disease Modeled: type 1 diabetes mellitus
Associated Mouse Gene: Ifngr2

Allelic Composition	Genetic Background	Reference	Phenotypes
Ifngr2tm1Pbro/Ifngr2tm1Pbro	NOD.129S1-Ifngr2^tm1Pbro	J:72818	View

Mouse Models

Human Disease Modeled: type 1 diabetes mellitus
Associated Mouse Gene: Ighm

Allelic Composition	Genetic Background	Reference	Phenotypes
Ighmtm1Cgn/Ighmtm1Cgn Tg(Igh-VB1-8/Igh-6m)1Mjsk/?	NODCaj.Cg-Ighm^tm1Cgn Tg(Igh-VB1-8/Igh-6m)1Mjsk/FswJ	J:93190	View
Tg(Igh-6/Igh-V281)3Jwt/0	NOD.B6-Tg(Igh-6/Igh-V281)3Jwt	J:91865	View
Tg(Igh-6/Igh-V125)2Jwt/0 Tg(Igk-C/Igk-V125)1Jwt/0	NOD.B6-Tg(Igh-6/Igh-V125)2Jwt Tg(Igk-C/Igk-V125)1Jwt	J:91865	View
Ighmtm1Cgn/Ighm+ Tg(Igh-6/Igh-V281)3Jwt/0	NOD.Cg-Ighm^tm1Cgn Tg(Igh-6/Igh-V281)3Jwt	J:91865	View
Ighmtm1Cgn/Ighm+	NOD.129S2-Ighm^tm1Cgn	J:37287	View

NOT Models
No similarity to the expected human disease phenotype was found.

Allelic Composition	Genetic Background	Reference	Phenotypes
Ighmtm1Cgn/Ighmtm1Cgn	NOD.129S2-Ighm^tm1Cgn	J:37287	View
Ighmtm1Cgn/Ighmtm1Cgn	NOD.129S2-Ighm^tm1Cgn/DvsJ	J:80859	View
Ighmtm1Cgn/Ighmtm1Cgn Tg(IghelMD4)4Ccg/Tg(IghelMD4)4Ccg	NOD.Cg-Ighm^tm1Cgn Tg(IghelMD4)4Ccg/DvsJ	J:80859	View

Mouse Models

Human Disease Modeled: type 1 diabetes mellitus
Associated Mouse Gene: Il4

Allelic Composition	Genetic Background	Reference	Phenotypes
Il4tm1Cgn/Il4tm1Cgn	either: NOD.129-Il4^tm1Cgn or (involves: 129 * NOD)	J:85924	View
Il4tm1Cgn/Il4tm1Cgn Tg(TcraBDC2.5,TcrbBDC2.5)1Doi/0	NOD.Cg-Il4^tm1Cgn Tg(TcraBDC2.5,TcrbBDC2.5)1Doi	J:85924	View

Mouse Models

Human Disease Modeled: type 1 diabetes mellitus
Associated Mouse Gene: Irak3

Allelic Composition	Genetic Background	Reference	Phenotypes
Irak3tm1Flv/Irak3tm1Flv	NOD.129S1(B6)-Irak3^tm1Flv	J:229884	View

Mouse Models

Human Disease Modeled: type 1 diabetes mellitus
Associated Mouse Gene: Mbd2

Allelic Composition	Genetic Background	Reference	Phenotypes
Mbd2tm1Bh/Mbd2tm1Bh	NOD.129P2(B6)-Mbd2^tm1Bh	J:323838	View

Mouse Models

Human Disease Modeled: type 1 diabetes mellitus
Associated Mouse Gene: Nos2

Allelic Composition	Genetic Background	Reference	Phenotypes
Tg(Ins2-Nos2)40Okam/0 Tg(Kdr-AGER)102Hyam/0	involves: C57BL/6J * CBA/J * CD-1 * DBA/2	J:70495	View
Tg(Ins2-Nos2)40Okam/0	involves: 129P2/OlaHsd * C57BL/6 * CD-1 * DBA/2	J:116040	View
Tg(Ins2-Nos2)31Okam/0	involves: C57BL/6 * CD-1 * DBA/2	J:45520	View
Tg(Ins2-Nos2)40Okam/0	involves: C57BL/6 * CD-1 * DBA/2	J:4552	View
Agertm1.1Hyam/Agertm1.1Hyam Tg(Ins2-Nos2)40Okam/0	involves: 129P2/OlaHsd * C57BL/6 * CD-1 * DBA/2	J:116040	View

Mouse Models

Human Disease Modeled: type 1 diabetes mellitus
Associated Mouse Gene: Pdx1

Allelic Composition	Genetic Background	Reference	Phenotypes
Pdx1tm1Cvw/Pdx1tm4Cvw Tg(Ins2-cre)25Mgn/0	involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6 * DBA	J:130389	View

Mouse Models

Human Disease Modeled: type 1 diabetes mellitus
Associated Mouse Gene: Prf1

Allelic Composition	Genetic Background	Reference	Phenotypes
Prf1tm1Clrk/Prf1tm1Clrk	involves: 129S7/SvEvBrd * BALB/c * NOD	J:64051	View
Prf1tm1Clrk/Prf1tm1Clrk Tg(INS-Il10)#Sar/0	involves: 129S7/SvEvBrd * BALB/c * NOD	J:64051	View

Mouse Models

Human Disease Modeled: type 1 diabetes mellitus
Associated Mouse Gene: Sell

Allelic Composition	Genetic Background	Reference	Phenotypes
Selltm1Flv/Selltm1Flv	involves: C57BL/6 * NOD	J:88974	View
Selltm1Flv/Selltm1Flv	NOD.Cg-Sell^tm1Flv	J:88974	View
Selltm1Flv/Sell+	involves: C57BL/6 * NOD	J:88974	View
Selltm1Flv/Sell+	NOD.Cg-Sell^tm1Flv	J:88974	View

Mouse Models

Human Disease Modeled: type 1 diabetes mellitus
Associated Mouse Gene: Senp1

Allelic Composition	Genetic Background	Reference	Phenotypes
Senp1tm1Wami/Senp1tm1Wami Tg(Fabp4-cre)#Abel/0	B6.Cg-Senp1^tm1Wami Tg(Fabp4-cre)#Abel	J:228009	View

Mouse Models

Human Disease Modeled: type 1 diabetes mellitus
Associated Mouse Gene: Stat4

Allelic Composition	Genetic Background	Reference	Phenotypes
Stat4tm1Gru/Stat4tm1Gru	C.129S2-Stat4^tm1Gru	J:106340	View
Stat4tm1Gru/Stat4tm1Gru Tg(Ins2-NP)25-3Olds/0	involves: 129S2/SvPas * BALB/c * C57BL/6	J:107047	View
Stat4tm1Gru/Stat4tm1Gru Tg(Ins2-GP)34-20Olds/0	involves: 129S2/SvPas * BALB/c * C57BL/6	J:107047	View
Stat4tm1Gru/Stat4+	NOD.129S2-Stat4^tm1Gru	J:90600	View

NOT Models
No similarity to the expected human disease phenotype was found.

Allelic Composition	Genetic Background	Reference	Phenotypes
Stat4tm1Gru/Stat4tm1Gru	NOD.129S2-Stat4^tm1Gru	J:90600	View

Mouse Models

Human Disease Modeled: type 1 diabetes mellitus
Associated Mouse Gene: Tnfsf4

Allelic Composition	Genetic Background	Reference	Phenotypes
Tnfsf4tm1Shr/Tnfsf4tm1Shr	NOD.129S4-Tnfsf4^tm1Shr	J:86926	View

Mouse Models

Human Disease Modeled: type 1 diabetes mellitus

Allelic Composition	Genetic Background	Reference	Phenotypes
Agertm1.1Hyam/Agertm1.1Hyam Tg(Ins2-Nos2)40Okam/0	involves: 129P2/OlaHsd * C57BL/6 * CD-1 * DBA/2	J:116040	View

Mouse Models

Human Disease Modeled: type 1 diabetes mellitus

Allelic Composition	Genetic Background	Reference	Phenotypes
Tg(Ins1-Cd80)378Psoh/0 Tg(Ins2-GP)#Psoh/0 Tg(TcrLCMV)327Sdz/0	involves: C57BL/6 * DBA/2 * FVB/N	J:209714	View
Cd80tm1Shr/Cd80tm1Shr Cd86tm2Shr/Cd86tm2Shr	involves: 129S4/SvJae * NOD	J:61905	View

Mouse Models

Human Disease Modeled: type 1 diabetes mellitus

Allelic Composition	Genetic Background	Reference	Phenotypes
Cd80tm1Shr/Cd80tm1Shr Cd86tm2Shr/Cd86tm2Shr	involves: 129S4/SvJae * NOD	J:61905	View

Mouse Models

Human Disease Modeled: type 1 diabetes mellitus

Allelic Composition	Genetic Background	Reference	Phenotypes
H2-Ab1b-tm1Gru/H2-Ab1b-tm1Gru Tg(HLA-DQA1,HLA-DQB1)1Dv/0 Tg(HLA-DRB1)31Dmz/0 Tg(Ins2-CD80)3B7Flv/0	involves: 129S2/SvPas * C57BL/6 * C57BL/10SnJ * CBA * SJL	J:68641	View
H2-Ab1b-tm1Gru/H2-Ab1b-tm1Gru Tg(HLA-DQA1,HLA-DQB1)1Dv/0 Tg(Ins2-CD80)3B7Flv/0	B6.Cg-H2-Ab1^b-tm1Gru Tg(HLA-DQA1,HLA-DQB1)1Dv Tg(Ins2-CD80)3B7Flv	J:59245	View
H2-Ab1b-tm1Gru/H2-Ab1b-tm1Gru Tg(HLA-DRB1)31Dmz/0 Tg(Ins2-CD80)3B7Flv/0	involves: 129S2/SvPas * C57BL/6 * CBA * SJL	J:68641	View

NOT Models
No similarity to the expected human disease phenotype was found.

Allelic Composition	Genetic Background	Reference	Phenotypes
H2-Ab1b-tm1Gru/H2-Ab1b-tm1Gru Tg(CD2-CD4,HLA-DQA1,HLA-DQB1)1Ell/Tg(CD2-CD4,HLA-DQA1,HLA-DQB1)1Ell	NOD.Cg-H2-Ab1^b-tm1Gru Tg(CD2-CD4,HLA-DQA1,HLA-DQB1)1Ell	J:87013	View

Mouse Models

Human Disease Modeled: type 1 diabetes mellitus

NOT Models
No similarity to the expected human disease phenotype was found.

Allelic Composition	Genetic Background	Reference	Phenotypes
Icam1tm1Jcgr/Icam1tm1Jcgr Tg(INS-Il10)#Sar/0	NOD.Cg-Icam1^tm1Jcgr Tg(INS-Il10)#Sar	J:98583	View

Mouse Models

Human Disease Modeled: type 1 diabetes mellitus

NOT Models
No similarity to the expected human disease phenotype was found.

Allelic Composition	Genetic Background	Reference	Phenotypes
Tlr2tm1Aki/Tlr2tm1Aki	NOD.129P2-Tlr2^tm1Aki	J:124334	View

Mouse Models

Human Disease Modeled: type 1 diabetes mellitus
Associated Mouse Complex/Cluster/Region: H2-I

Allelic Composition	Genetic Background	Reference	Phenotypes
Tg(H2-Ead)12Lt/0	NOD/ShiLt-Tg(H2-Ea^d)12Lt	J:36435	View

NOT Models
No similarity to the expected human disease phenotype was found.

Allelic Composition	Genetic Background	Reference	Phenotypes
Tg(H2-Ead)5Lt/0	NOD/ShiLt-Tg(H2-Ea^d)5Lt	J:36435	View

Mouse Models

Human Disease Modeled: type 1 diabetes mellitus
Associated Mouse Complex/Cluster/Region: Tcra

Allelic Composition	Genetic Background	Reference	Phenotypes
H2g7/H2g7 Ins2tm1Jja/Ins2tm1Jja Rag1tm1Mom/Rag1tm1Mom Tg(TcraBDC12-4.1)10Jos/0 Tg(TcrbBDC12-4.1)82Gse/0	involves: 129S2/SvPas * 129S7/SvEvBrd * C57BL/6 * FVB * NOD	J:111874	View
Tg(TcraAI4)1Dvs/0	NOD-Tg(TcraAI4)1Dvs	J:93553	View
Rag1tm1Mom/Rag1tm1Mom Tg(TcraBDC12-4.1)10Jos/0 Tg(TcrbBDC12-4.1)82Gse/0	involves: 129S7/SvEvBrd * C57BL/6 * FVB * NOD	J:111874	View
Tg(Ins1-Cd80)378Psoh/0 Tg(Ins2-GP)#Psoh/0 Tg(TcrLCMV)327Sdz/0	involves: C57BL/6 * DBA/2 * FVB/N	J:209714	View
Tg(TcraTcrbNY8.3)1Pesa/?	involves: C57BL/6 * NOD * SJL	J:44202	View
H2g7/H2g7 Rag1tm1Mom/Rag1tm1Mom Tg(TcraBDC12-4.1)10Jos/0 Tg(TcrbBDC12-4.1)82Gse/0	involves: 129S7/SvEvBrd * C57BL/6 * FVB * NOD	J:111874	View
Cd4tm1Knw/Cd4tm1Knw Tg(TcraAI4)1Dvs/0 Tg(TcrbAI4)1Dvs/0	NOD.Cg-Cd4^tm1Knw Tg(TcraAI4)1Dvs Tg(TcrbAI4)1Dvs	J:93553	View
H2g7/H2q Rag1tm1Mom/Rag1tm1Mom Tg(TcraBDC12-4.1)10Jos/0 Tg(TcrbBDC12-4.1)82Gse/0	involves: 129S7/SvEvBrd * C57BL/6 * FVB * NOD	J:111874	View
Prkdcscid/Prkdcscid Tg(TcraAI4)1Dvs/0 Tg(TcrbAI4)1Dvs/0	NOD.Cg-Prkdc^scid Tg(TcraAI4)1Dvs Tg(TcrbAI4)1Dvs	J:93553	View
Fastm1Vbo/Fastm1Vbo Tg(Ins2-cre)25Mgn/0 Tg(Ins2-HA)165Bri/0 Tg(Tcra/Tcrb)1Vbo/0	Not Specified	J:85985	View
Rag1tm1Mom/Rag1tm1Mom Tg(TcraAI4)1Dvs/0 Tg(TcrbAI4)1Dvs/0	NOD.Cg-Rag1^tm1Mom Tg(TcraAI4)1Dvs Tg(TcrbAI4)1Dvs/Dvs	J:94192	View
Tg(TcraAI4)1Dvs/0 Tg(TcrbAI4)1Dvs/0	NOD-Tg(TcraAI4)1Dvs Tg(TcrbAI4)1Dvs	J:93553	View
Il4tm1Cgn/Il4tm1Cgn Tg(TcraBDC2.5,TcrbBDC2.5)1Doi/0	NOD.Cg-Il4^tm1Cgn Tg(TcraBDC2.5,TcrbBDC2.5)1Doi	J:85924	View

NOT Models
No similarity to the expected human disease phenotype was found.

Allelic Composition	Genetic Background	Reference	Phenotypes
B2mtm1Unc/B2mtm1Unc Tg(TcraAI4)1Dvs/0 Tg(TcrbAI4)1Dvs/0	NOD.Cg-B2m^tm1Unc Tg(TcraAI4)1Dvs Tg(TcrbAI4)1Dvs	J:93553	View

Mouse Models

Human Disease Modeled: type 1 diabetes mellitus
Associated Mouse Transgene: Tg(Cryaa-TAg,Ins2-CALM1)26Ove

Allelic Composition	Genetic Background	Reference	Phenotypes
Tg(Cryaa-TAg,Ins2-CALM1)26Ove/0	FVB(Cg)-Tg(Cryaa-Tag,Ins2-CALM1)26Ove/PneJ	J:97926	View
Tg(Cryaa-TAg,Ins2-CALM1)26Ove/0	FVB-Tg(Cryaa-TAg,Ins2-CALM1)26Ove	J:94602	View

Mouse Models

Human Disease Modeled: type 1 diabetes mellitus
Associated Mouse Transgene: Tg(H2-Ea-G6pc2)69Tkay

Allelic Composition	Genetic Background	Reference	Phenotypes
Tg(H2-Ea-G6pc2)69Tkay/?	NOD-Tg(H2-Ea-G6pc2)69Tkay	J:117352	View

Mouse Models

Human Disease Modeled: type 1 diabetes mellitus
Associated Mouse Transgene: Tg(H2-Ea-Ins2)1Wehi

Allelic Composition	Genetic Background	Reference	Phenotypes
Tg(H2-Ea-Ins2)1Wehi/0	NOD/ShiLtJWehi-Tg(H2-Ea-Ins2)1Wehi	J:100251	View

Mouse Models

Human Disease Modeled: type 1 diabetes mellitus
Associated Mouse Transgene: Tg(H2-Ea^d)12Lt

Allelic Composition	Genetic Background	Reference	Phenotypes
Tg(H2-Ead)12Lt/0	NOD/ShiLt-Tg(H2-Ea^d)12Lt	J:36435	View

Mouse Models

Human Disease Modeled: type 1 diabetes mellitus
Associated Mouse Transgene: Tg(HLA-A/H2-D/B2M)1Dvs

Allelic Composition	Genetic Background	Reference	Phenotypes
Tg(HLA-A/H2-D/B2M)1Dvs/0	NOD/ShiLtDvs-Tg(HLA-A/H2-D/B2M)1Dvs	J:121685	View
B2mtm1Unc/B2mtm1Unc Tg(HLA-A/H2-D/B2M)1Dvs/0	NOD.Cg-B2m^tm1Unc Tg(HLA-A/H2-D/B2M)1Dvs	J:121685	View

Mouse Models

Human Disease Modeled: type 1 diabetes mellitus
Associated Mouse Transgene: Tg(Igh-6/Igh-V281)3Jwt

Allelic Composition	Genetic Background	Reference	Phenotypes
Tg(Igh-6/Igh-V281)3Jwt/0	NOD.B6-Tg(Igh-6/Igh-V281)3Jwt	J:91865	View
Ighmtm1Cgn/Ighm+ Tg(Igh-6/Igh-V281)3Jwt/0	NOD.Cg-Ighm^tm1Cgn Tg(Igh-6/Igh-V281)3Jwt	J:91865	View

Mouse Models

Human Disease Modeled: type 1 diabetes mellitus
Associated Mouse Transgene: Tg(Igh-VB1-8/Igh-6m)1Mjsk

Allelic Composition	Genetic Background	Reference	Phenotypes
Ighmtm1Cgn/Ighmtm1Cgn Tg(Igh-VB1-8/Igh-6m)1Mjsk/?	NODCaj.Cg-Ighm^tm1Cgn Tg(Igh-VB1-8/Igh-6m)1Mjsk/FswJ	J:93190	View

Mouse Models

Human Disease Modeled: type 1 diabetes mellitus
Associated Mouse Transgene: Tg(IghelMD4)4Ccg

Allelic Composition	Genetic Background	Reference	Phenotypes
Tg(IghelMD4)4Ccg/Tg(IghelMD4)4Ccg	NOD.B6-Tg(IghelMD4)4Ccg/DvsJ	J:80859	View

NOT Models
No similarity to the expected human disease phenotype was found.

Allelic Composition	Genetic Background	Reference	Phenotypes
Ighmtm1Cgn/Ighmtm1Cgn Tg(IghelMD4)4Ccg/Tg(IghelMD4)4Ccg	NOD.Cg-Ighm^tm1Cgn Tg(IghelMD4)4Ccg/DvsJ	J:80859	View

Mouse Models

Human Disease Modeled: type 1 diabetes mellitus
Associated Mouse Transgene: Tg(Ins1-Cat,Tyr)25Pne

Allelic Composition	Genetic Background	Reference	Phenotypes
Tg(Ins1-Cat,Tyr)25Pne/0	involves: FVB	J:59725	View
Tg(Ins1-Cat,Tyr)25Pne/0	NOD.FVB-Tg(Ins1-Cat,Tyr)25Pne	J:108415	View

Mouse Models

Human Disease Modeled: type 1 diabetes mellitus
Associated Mouse Transgene: Tg(Ins2*Y16A)3Ell

Allelic Composition	Genetic Background	Reference	Phenotypes
Tg(Ins2*Y16A)3Ell/0	NOD-Tg(Ins2*Y16A)3Ell	J:98583	View

NOT Models
No similarity to the expected human disease phenotype was found.

Allelic Composition	Genetic Background	Reference	Phenotypes
Ins1tm1Jja/Ins1tm1Jja Ins2tm1Jja/Ins2tm1Jja Tg(Ins2*Y16A)3Ell/0	NOD.Cg-Ins1^tm1Jja Ins2^tm1Jja Tg(Ins2*Y16A)3Ell	J:98583	View

Mouse Models

Human Disease Modeled: type 1 diabetes mellitus
Associated Mouse Transgene: Tg(Ins2-CD80)3B7Flv

Allelic Composition	Genetic Background	Reference	Phenotypes
H2-Ab1b-tm1Gru/H2-Ab1b-tm1Gru Tg(HLA-DQA1,HLA-DQB1)1Dv/0 Tg(HLA-DRB1)31Dmz/0 Tg(Ins2-CD80)3B7Flv/0	involves: 129S2/SvPas * C57BL/6 * C57BL/10SnJ * CBA * SJL	J:68641	View
Tg(Ins2-CD80)3B7Flv/?	involves: C57BL/6 * CBA/Ca * NOD/Caj	J:26618	View
H2-Ab1b-tm1Gru/H2-Ab1b-tm1Gru Tg(HLA-DQA1,HLA-DQB1)1Dv/0 Tg(Ins2-CD80)3B7Flv/0	B6.Cg-H2-Ab1^b-tm1Gru Tg(HLA-DQA1,HLA-DQB1)1Dv Tg(Ins2-CD80)3B7Flv	J:59245	View
H2-Ab1b-tm1Gru/H2-Ab1b-tm1Gru Tg(HLA-DRB1)31Dmz/0 Tg(Ins2-CD80)3B7Flv/0	involves: 129S2/SvPas * C57BL/6 * CBA * SJL	J:68641	View

Mouse Models

Human Disease Modeled: type 1 diabetes mellitus
Associated Mouse Transgene: Tg(Ins2-Fasl)24Ach

Allelic Composition	Genetic Background	Reference	Phenotypes
Tg(Ins2-Fasl)24Ach/0	NOD-Tg(Ins2-Fasl)24Ach/J	J:78679	View
Tg(Ins2-Fas*I246N)1Ach/0 Tg(Ins2-Fasl)24Ach/0	NOD-Tg(Ins2-Fas*I246N)1Ach Tg(Ins2-Fasl)24Ach	J:81416	View
Faslpr/Faslpr Tg(Ins2-Fasl)24Ach/0	NOD.Cg-Fas^lpr Tg(Ins2-Fasl)24Ach	J:81416	View

Mouse Models

Human Disease Modeled: type 1 diabetes mellitus
Associated Mouse Transgene: Tg(Ins2-GP)34-20Olds

Allelic Composition	Genetic Background	Reference	Phenotypes
Tg(Ins2-GP)34-20Olds/0	involves: BALB/c * C57BL/6	J:81287	View
Stat4tm1Gru/Stat4tm1Gru Tg(Ins2-GP)34-20Olds/0	involves: 129S2/SvPas * BALB/c * C57BL/6	J:107047	View

Mouse Models

Human Disease Modeled: type 1 diabetes mellitus
Associated Mouse Transgene: Tg(Ins2-HBEGF)5Rin

Allelic Composition	Genetic Background	Reference	Phenotypes
Tg(Ins2-HBEGF)5Rin/?	C57BL/6-Tg(Ins2-HBEGF)5Rin	J:204420	View

Mouse Models

Human Disease Modeled: type 1 diabetes mellitus
Associated Mouse Transgene: Tg(Ins2-Nos2)31Okam

Allelic Composition	Genetic Background	Reference	Phenotypes
Tg(Ins2-Nos2)31Okam/0	involves: C57BL/6 * CD-1 * DBA/2	J:45520	View

Mouse Models

Human Disease Modeled: type 1 diabetes mellitus
Associated Mouse Transgene: Tg(Ins2-Nos2)40Okam

Allelic Composition	Genetic Background	Reference	Phenotypes
Tg(Ins2-Nos2)40Okam/0 Tg(Kdr-AGER)102Hyam/0	involves: C57BL/6J * CBA/J * CD-1 * DBA/2	J:70495	View
Tg(Ins2-Nos2)40Okam/0	involves: 129P2/OlaHsd * C57BL/6 * CD-1 * DBA/2	J:116040	View
Tg(Ins2-Nos2)40Okam/0	involves: C57BL/6 * CD-1 * DBA/2	J:4552	View
Agertm1.1Hyam/Agertm1.1Hyam Tg(Ins2-Nos2)40Okam/0	involves: 129P2/OlaHsd * C57BL/6 * CD-1 * DBA/2	J:116040	View

Mouse Models

Human Disease Modeled: type 1 diabetes mellitus
Associated Mouse Transgene: Tg(Ins2-NP)25-3Olds

Allelic Composition	Genetic Background	Reference	Phenotypes
Tg(Ins2-NP)25-3Olds/0	involves: BALB/c * C57BL/6	J:81284	View
Stat4tm1Gru/Stat4tm1Gru Tg(Ins2-NP)25-3Olds/0	involves: 129S2/SvPas * BALB/c * C57BL/6	J:107047	View

Mouse Models

Human Disease Modeled: type 1 diabetes mellitus
Associated Mouse Transgene: Tg(INS-MT2A,Tyr)1Pne

Allelic Composition	Genetic Background	Reference	Phenotypes
Tg(INS-MT2A,Tyr)1Pne/0	FVB-Tg(INS-MT2A,Tyr)1Pne	J:100251	View
Tg(INS-MT2A,Tyr)1Pne/0	NOD.FVB-Tg(INS-MT2A,Tyr)1Pne	J:108415	View

Mouse Models

Human Disease Modeled: type 1 diabetes mellitus
Associated Mouse Transgene: Tg(INS-SOD2)3Pne

Allelic Composition	Genetic Background	Reference	Phenotypes
Tg(INS-SOD2)3Pne/0	NOD.FVB-Tg(INS-SOD2)3Pne	J:108415	View

Mouse Models

Human Disease Modeled: type 1 diabetes mellitus
Associated Mouse Transgene: Tg(TcraAI4)1Dvs

Allelic Composition	Genetic Background	Reference	Phenotypes
Tg(TcraAI4)1Dvs/0	NOD-Tg(TcraAI4)1Dvs	J:93553	View
Cd4tm1Knw/Cd4tm1Knw Tg(TcraAI4)1Dvs/0 Tg(TcrbAI4)1Dvs/0	NOD.Cg-Cd4^tm1Knw Tg(TcraAI4)1Dvs Tg(TcrbAI4)1Dvs	J:93553	View
Prkdcscid/Prkdcscid Tg(TcraAI4)1Dvs/0 Tg(TcrbAI4)1Dvs/0	NOD.Cg-Prkdc^scid Tg(TcraAI4)1Dvs Tg(TcrbAI4)1Dvs	J:93553	View
Rag1tm1Mom/Rag1tm1Mom Tg(TcraAI4)1Dvs/0 Tg(TcrbAI4)1Dvs/0	NOD.Cg-Rag1^tm1Mom Tg(TcraAI4)1Dvs Tg(TcrbAI4)1Dvs/Dvs	J:94192	View
Tg(TcraAI4)1Dvs/0 Tg(TcrbAI4)1Dvs/0	NOD-Tg(TcraAI4)1Dvs Tg(TcrbAI4)1Dvs	J:93553	View

NOT Models
No similarity to the expected human disease phenotype was found.

Allelic Composition	Genetic Background	Reference	Phenotypes
B2mtm1Unc/B2mtm1Unc Tg(TcraAI4)1Dvs/0 Tg(TcrbAI4)1Dvs/0	NOD.Cg-B2m^tm1Unc Tg(TcraAI4)1Dvs Tg(TcrbAI4)1Dvs	J:93553	View

Mouse Models

Human Disease Modeled: type 1 diabetes mellitus
Associated Mouse Transgene: Tg(TcraTcrbNY8.3)1Pesa

Allelic Composition	Genetic Background	Reference	Phenotypes
Tg(TcraTcrbNY8.3)1Pesa/?	involves: C57BL/6 * NOD * SJL	J:44202	View

Mouse Models

Human Disease Modeled: type 1 diabetes mellitus

NOT Models
No similarity to the expected human disease phenotype was found.

Allelic Composition	Genetic Background	Reference	Phenotypes
B2mtm1Jae/B2mtm1Jae Tg(B2m)1Rms/0 Tg(INS-cre)2Rms/0	involves: 129S2/SvPas * NOD	J:83635	View

Mouse Models

Human Disease Modeled: type 1 diabetes mellitus

NOT Models
No similarity to the expected human disease phenotype was found.

Allelic Composition	Genetic Background	Reference	Phenotypes
B2mtm1Unc/B2mtm1Unc Ciitatm1Ccum/Ciitatm1Ccum	NOD.Cg-B2m^tm1Unc Ciita^tm1Ccum	J:107051	View

Mouse Models

Human Disease Modeled: type 1 diabetes mellitus

NOT Models
No similarity to the expected human disease phenotype was found.

Allelic Composition	Genetic Background	Reference	Phenotypes
B2mtm1Unc/B2mtm1Unc	NOD.129P2-B2m^tm1Unc	J:17000	View

Mouse Models

Human Disease Modeled: type 1 diabetes mellitus

NOT Models
No similarity to the expected human disease phenotype was found.

Allelic Composition	Genetic Background	Reference	Phenotypes
Ctnna2tm1Mta/Ctnna2tm1Mta	Not Specified	J:83635	View

Mouse Models

Human Disease Modeled: type 1 diabetes mellitus

NOT Models
No similarity to the expected human disease phenotype was found.

Allelic Composition	Genetic Background	Reference	Phenotypes
Cd4tm1Knw/Cd4tm1Knw	NOD.Cg-Cd4^tm1Knw	J:93553	View

Mouse Models

Human Disease Modeled: type 1 diabetes mellitus

NOT Models
No similarity to the expected human disease phenotype was found.

Allelic Composition	Genetic Background	Reference	Phenotypes
Faslpr/Faslpr	NOD.MRL(B6)-Fas^lpr	J:64051	View

Mouse Models

Human Disease Modeled: type 1 diabetes mellitus

NOT Models
No similarity to the expected human disease phenotype was found.

Allelic Composition	Genetic Background	Reference	Phenotypes
Casp3tm1Mak/Casp3tm1Mak	B6.129P2-Casp3^tm1Mak	J:97650	View

Mouse Models

Human Disease Modeled: type 1 diabetes mellitus

NOT Models
No similarity to the expected human disease phenotype was found.

Allelic Composition	Genetic Background	Reference	Phenotypes
Ciitatm1Ccum/Ciitatm1Ccum	NOD.129S2(B6)-Ciita^tm1Ccum	J:106081	View

Mouse Models

Human Disease Modeled: type 1 diabetes mellitus

NOT Models
No similarity to the expected human disease phenotype was found.

Allelic Composition	Genetic Background	Reference	Phenotypes
Parp1tm1Hsmm/Parp1tm1Hsmm	involves: 129S4/SvJae	J:53360	View

Mouse Models

Human Disease Modeled: type 1 diabetes mellitus

NOT Models
No similarity to the expected human disease phenotype was found.

Allelic Composition	Genetic Background	Reference	Phenotypes
Tg(TcrbAI4)1Dvs/0	NOD-Tg(TcrbAI4)1Dvs	J:93553	View

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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