amyotrophic lateral sclerosis type 1 Disease Ontology Browser

Mouse Models

Human Disease Modeled: amyotrophic lateral sclerosis type 1
Associated Mouse Gene: Sod1

Allelic Composition	Genetic Background	Reference	Phenotypes
Sod1m1H/Sod1m1H	involves: C3H/HeH * C57BL/6J	J:219360	View
Tg(Sod1*G86R)M1Jwg/0	involves: FVB/N	J:22628, J:58733, J:91800	View

Mouse Models

Human Disease Modeled: amyotrophic lateral sclerosis type 1
Associated Mouse Gene: Sncg

Allelic Composition	Genetic Background	Reference	Phenotypes
Tg(Thy1-Sncg)HvP36Putt/?	C57BL/6-Tg(Thy1-Sncg)HvP36Putt	J:185793	View

Mouse Models

Human Disease Modeled: amyotrophic lateral sclerosis type 1
Associated Mouse Gene: Sod2

Allelic Composition	Genetic Background	Reference	Phenotypes
Sod2tm1Cje/Sod2tm1Cje	involves: C57BL/6J	J:45913	View

Mouse Models

Human Disease Modeled: amyotrophic lateral sclerosis type 1
Associated Mouse Gene: Vegfa

Allelic Composition	Genetic Background	Reference	Phenotypes
Vegfatm2Pec/Vegfatm2Pec	involves: 129S1/Sv * 129X1/SvJ	J:69797	View

Mouse Models

Human Disease Modeled: amyotrophic lateral sclerosis type 1
Associated Mouse Gene: Vps54

Allelic Composition	Genetic Background	Reference	Phenotypes
Vps54wr/Vps54wr	involves: C57BL/6J * C57BL/Fa	J:181019, J:196432	View

Mouse Models

Human Disease Modeled: amyotrophic lateral sclerosis type 1
Associated Mouse Transgene: Tg(Myl1-SOD1*G93A)#Amu

Allelic Composition	Genetic Background	Reference	Phenotypes
Tg(Myl1-SOD1*G93A)#Amu/0	FVB/NJ-Tg(Myl1-SOD1*G93A)#Amu	J:143747	View

Mouse Models

Human Disease Modeled: amyotrophic lateral sclerosis type 1
Associated Mouse Transgene: Tg(NEFH)200Jpj

Allelic Composition	Genetic Background	Reference	Phenotypes
Tg(NEFH)200Jpj/Tg(NEFH)200Jpj	Not Specified	J:69180	View
Tg(NEFH)200Jpj/0	Not Specified	J:69180	View

Mouse Models

Human Disease Modeled: amyotrophic lateral sclerosis type 1
Associated Mouse Transgene: Tg(NFH)120Jpj

Allelic Composition	Genetic Background	Reference	Phenotypes
Tg(NFH)120Jpj/Tg(NFH)120Jpj	Not Specified	J:69180	View
Tg(NFH)120Jpj/0	Not Specified	J:69180	View

Mouse Models

Human Disease Modeled: amyotrophic lateral sclerosis type 1
Associated Mouse Transgene: Tg(Prnp-Immt/SOD1*G93A)7Gmnf

Allelic Composition	Genetic Background	Reference	Phenotypes
Tg(Prnp-Immt/SOD1G93A)7Gmnf/Tg(Prnp-Immt/SOD1G93A)7Gmnf	involves: C57BL/6 * CBA * SJL	J:177846	View

Mouse Models

Human Disease Modeled: amyotrophic lateral sclerosis type 1
Associated Mouse Transgene: Tg(Prnp-SOD1*G37R,-PSEN1)110Dbo

Allelic Composition	Genetic Background	Reference	Phenotypes
Tg(Prnp-SOD1G37R,-PSEN1)110Dbo/Tg(Prnp-SOD1G37R,-PSEN1)110Dbo	involves: C3H * C57BL/6	J:104655	View

Mouse Models

Human Disease Modeled: amyotrophic lateral sclerosis type 1
Associated Mouse Transgene: Tg(SOD1*)125Dbo

Allelic Composition	Genetic Background	Reference	Phenotypes
Tg(SOD1*)125Dbo/?	involves: C3H/HeJ * C57BL/6J	J:86421	View

Mouse Models

Human Disease Modeled: amyotrophic lateral sclerosis type 1
Associated Mouse Transgene: Tg(SOD1*)D-14Dbo

Allelic Composition	Genetic Background	Reference	Phenotypes
Tg(SOD1*)D-14Dbo/0	involves: C3H/HeJ * C57BL/6J	J:218091	View
Tg(SOD1)2Gur/0 Tg(SOD1*)D-14Dbo/0	involves: C3H/HeJ * C57BL/6 * C57BL/6J * SJL	J:218091	View

Mouse Models

Human Disease Modeled: amyotrophic lateral sclerosis type 1
Associated Mouse Transgene: Tg(SOD1*)DF7Yaw

Allelic Composition	Genetic Background	Reference	Phenotypes
Tg(SOD1)DF7Yaw/Tg(SOD1)DF7Yaw	C57BL/6-Tg(SOD1*)DF7Yaw	J:97932	View
Tg(SOD1*)DF7Yaw/0	C57BL/6-Tg(SOD1*)DF7Yaw	J:97932	View

Mouse Models

Human Disease Modeled: amyotrophic lateral sclerosis type 1
Associated Mouse Transgene: Tg(SOD1*G37R)1Dwc

Allelic Composition	Genetic Background	Reference	Phenotypes
Isl1tm1(cre)Tmj/Isl1+ Tg(SOD1*G37R)1Dwc/0	involves: 129X1/SvJ * C57BL/6	J:109131	View
Tg(ITGAM-cre)2781Gkl/0 Tg(SOD1*G37R)1Dwc/0	involves: C57BL/6 * CBA	J:109131	View

Mouse Models

Human Disease Modeled: amyotrophic lateral sclerosis type 1
Associated Mouse Transgene: Tg(SOD1*G37R)9Dpr

Allelic Composition	Genetic Background	Reference	Phenotypes
Tg(SOD1*G37R)9Dpr/0	involves: C3H/HeJ * C57BL/6J	J:69178	View

Mouse Models

Human Disease Modeled: amyotrophic lateral sclerosis type 1
Associated Mouse Transgene: Tg(SOD1*G37R)29Dpr

Allelic Composition	Genetic Background	Reference	Phenotypes
Tg(SOD1*G37R)29Dpr/0	involves: C3H/HeJ * C57BL/6J	J:69178, J:119631	View

Mouse Models

Human Disease Modeled: amyotrophic lateral sclerosis type 1
Associated Mouse Transgene: Tg(SOD1*G37R)42Dpr

Allelic Composition	Genetic Background	Reference	Phenotypes
Tg(SOD1*G37R)42Dpr/0	involves: C3H/HeJ * C57BL/6J	J:69178	View

Mouse Models

Human Disease Modeled: amyotrophic lateral sclerosis type 1
Associated Mouse Transgene: Tg(SOD1*G37R)106Dpr

Allelic Composition	Genetic Background	Reference	Phenotypes
Tg(SOD1*G37R)106Dpr/0	involves: C3H/HeJ * C57BL/6J	J:69178	View

Mouse Models

Human Disease Modeled: amyotrophic lateral sclerosis type 1
Associated Mouse Transgene: Tg(SOD1*G85R)74Dwc

Allelic Composition	Genetic Background	Reference	Phenotypes
Tg(SOD1*G85R)74Dwc/?	Not Specified	J:77600	View

Mouse Models

Human Disease Modeled: amyotrophic lateral sclerosis type 1
Associated Mouse Transgene: Tg(SOD1*G85R)148Dwc

Allelic Composition	Genetic Background	Reference	Phenotypes
Tg(SOD1*G85R)148Dwc/?	Not Specified	J:77600	View

Mouse Models

Human Disease Modeled: amyotrophic lateral sclerosis type 1
Associated Mouse Transgene: Tg(SOD1*G85R)#Roos

Allelic Composition	Genetic Background	Reference	Phenotypes
Tg(SOD1*G85R)#Roos/0	involves: C57BL/6J	J:147156	View
Tg(SOD1)2Gur/0 Tg(SOD1*G85R)#Roos/0	involves: C57BL/6 * C57BL/6J * SJL	J:147156	View

Mouse Models

Human Disease Modeled: amyotrophic lateral sclerosis type 1
Associated Mouse Transgene: Tg(SOD1*G85R/EYFP)641Alho

Allelic Composition	Genetic Background	Reference	Phenotypes
Tg(SOD1G85R/EYFP)641Alho/Tg(SOD1G85R/EYFP)641Alho	involves: C57BL/6J * SJL/J	J:144475	View

Mouse Models

Human Disease Modeled: amyotrophic lateral sclerosis type 1
Associated Mouse Transgene: Tg(SOD1*G85R/EYFP)737Alho

Allelic Composition	Genetic Background	Reference	Phenotypes
Tg(SOD1G85R/EYFP)737Alho/Tg(SOD1G85R/EYFP)737Alho	involves: C57BL/6J * SJL/J	J:212250	View

Mouse Models

Human Disease Modeled: amyotrophic lateral sclerosis type 1
Associated Mouse Transgene: Tg(Sod1*G86R)M1Jwg

Allelic Composition	Genetic Background	Reference	Phenotypes
Tg(Sod1*G86R)M1Jwg/0	involves: FVB/N	J:22628, J:58733, J:91800	View

Mouse Models

Human Disease Modeled: amyotrophic lateral sclerosis type 1
Associated Mouse Transgene: Tg(SOD1*G93A)1Gur

Allelic Composition	Genetic Background	Reference	Phenotypes
Tg(SOD1*G93A)1Gur/0	B6.Cg-Tg(SOD1*G93A)1Gur	J:155140	View
Tg(SOD1*G93A)1Gur/0	B6.Cg-Tg(SOD1*G93A)1Gur/J	J:211734	View
Tg(SOD1*G93A)1Gur/0	B6SJL-Tg(SOD1*G93A)1Gur	J:144199	View
Tg(SOD1*G93A)1Gur/0	B6SJL-Tg(SOD1*G93A)1Gur/J	J:133155, J:143173, J:146652, J:212250	View
Tg(SOD1*G93A)1Gur/0	involves: C57BL/6 * SJL	J:76718, J:91800, J:109458, J:130581	View
Tg(SOD1)2Gur/0 Tg(SOD1*G93A)1Gur/0	involves: C57BL/6 * SJL	J:109458	View

Mouse Models

Human Disease Modeled: amyotrophic lateral sclerosis type 1
Associated Mouse Transgene: Tg(SOD1*G93A)2Gur

Allelic Composition	Genetic Background	Reference	Phenotypes
Tg(SOD1*G93A)2Gur/0	involves: C57BL/6 * SJL	J:32665, J:78629, J:89928	View

Mouse Models

Human Disease Modeled: amyotrophic lateral sclerosis type 1
Associated Mouse Transgene: Tg(SOD1*G93A)^dl1Gur

Allelic Composition	Genetic Background	Reference	Phenotypes
Tg(SOD1*G93A)dl1Gur/0	involves: C57BL/6 * SJL	J:106420	View
Cybbtm1Din/Y Tg(SOD1*G93A)dl1Gur/0	B6.Cg-Cybb^tm1Din Tg(SOD1*G93A)^dl1Gur	J:111782	View

Mouse Models

Human Disease Modeled: amyotrophic lateral sclerosis type 1
Associated Mouse Transgene: Tg(SOD1*G127X)716Mrkl

Allelic Composition	Genetic Background	Reference	Phenotypes
Tg(SOD1G127X)716Mrkl/Tg(SOD1G127X)716Mrkl	B6JBom.Cg-Tg(SOD1*G127X)716Mrkl	J:175594	View

Mouse Models

Human Disease Modeled: amyotrophic lateral sclerosis type 1
Associated Mouse Transgene: Tg(SOD1*H46R)#Maw

Allelic Composition	Genetic Background	Reference	Phenotypes
Tg(SOD1*H46R)#Maw/0	involves: C57BL/6 * DBA/2	J:99701	View

Mouse Models

Human Disease Modeled: amyotrophic lateral sclerosis type 1
Associated Mouse Transgene: Tg(SOD1*H46R)IAra

Allelic Composition	Genetic Background	Reference	Phenotypes
Tg(SOD1*H46R)IAra/0	involves: C57BL/6 * DBA/2	J:221350	View

Mouse Models

Human Disease Modeled: amyotrophic lateral sclerosis type 1
Associated Mouse Transgene: Tg(SOD1*H46R)LAra

Allelic Composition	Genetic Background	Reference	Phenotypes
Tg(SOD1*H46R)LAra/0	involves: C57BL/6 * DBA/2	J:221350	View

Mouse Models

Human Disease Modeled: amyotrophic lateral sclerosis type 1
Associated Mouse Transgene: Tg(SOD1*H46R*H48Q)58Dbo

Allelic Composition	Genetic Background	Reference	Phenotypes
Tg(SOD1H46RH48Q)58Dbo/0	involves: C3H/HeJ * C57BL/6J	J:119631	View

Mouse Models

Human Disease Modeled: amyotrophic lateral sclerosis type 1
Associated Mouse Transgene: Tg(SOD1*H46R*H48Q)139Dbo

Allelic Composition	Genetic Background	Reference	Phenotypes
Tg(SOD1H46RH48Q)139Dbo/0	involves: C3H/HeJ * C57BL/6J	J:119631	View

Mouse Models

Human Disease Modeled: amyotrophic lateral sclerosis type 1
Associated Mouse Transgene: Tg(SOD1*L126Z)45Dbo

Allelic Composition	Genetic Background	Reference	Phenotypes
Tg(SOD1*L126Z)45Dbo/0	involves: C3H/HeJ * C57BL/6J	J:219482	View

Mouse Models

Human Disease Modeled: amyotrophic lateral sclerosis type 1
Associated Mouse Transgene: Tg(SOD1*L126Z)#Deng

Allelic Composition	Genetic Background	Reference	Phenotypes
Tg(SOD1*L126Z)#Deng/0	involves: C57BL/6 * SJL	J:109458	View
Tg(SOD1)2Gur/0 Tg(SOD1*L126Z)#Deng/0	involves: C57BL/6 * SJL	J:109458	View

Mouse Models

Human Disease Modeled: amyotrophic lateral sclerosis type 1
Associated Mouse Transgene: Tg(Thy1-DCTN1*G59S)M2Pcw

Allelic Composition	Genetic Background	Reference	Phenotypes
Tg(Thy1-DCTN1*G59S)M2Pcw/?	involves: C57BL/6 * SJL	J:132857	View

Mouse Models

Human Disease Modeled: amyotrophic lateral sclerosis type 1
Associated Mouse Transgene: Tg(Thy1-Sncg)HvP36Putt

Allelic Composition	Genetic Background	Reference	Phenotypes
Tg(Thy1-Sncg)HvP36Putt/?	C57BL/6-Tg(Thy1-Sncg)HvP36Putt	J:185793	View

Mouse Models

Human Disease Modeled: amyotrophic lateral sclerosis type 1
Associated Mouse Transgene: Tg(Thy1-SOD1*G93A)T3Hgrd

Allelic Composition	Genetic Background	Reference	Phenotypes
Tg(Thy1-SOD1G93A)T3Hgrd/Tg(Thy1-SOD1G93A)T3Hgrd	involves: C57BL/6 * CBA * FVB	J:134095	View
Tg(Thy1-SOD1G93A)T1Hgrd/0 Tg(Thy1-SOD1G93A)T3Hgrd/0	involves: C57BL/6 * CBA * FVB	J:134095	View

Mouse Models

Human Disease Modeled: amyotrophic lateral sclerosis type 1

Allelic Composition	Genetic Background	Reference	Phenotypes
Tg(SOD1)2Gur/0 Tg(SOD1*A4V)A1073Gur/0	involves: C57BL/6 * SJL	J:109458	View

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