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Disease Ontology Browser
Werner syndrome (DOID:5688)
Alliance: disease page
Synonyms: adult premature ageing syndrome; adult progeria; Werner's syndrome; WS
Alt IDs: OMIM:277700, MESH:D014898, NCI:C3447, ORDO:902, UMLS_CUI:C0043119
Definition: A progeroid syndrome characterized by premature aging and age-related phenotypes such as atherosclerosis, arteriosclerosis, cataracts, osteoporosis, soft tissue calcification, premature thinning, graying, and loss of hair, as well as a high incidence of some types of cancers and that has_material_basis_in mutations in the WRN gene, on chromosome 8.

Disease References using Mouse Models (4)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory