Disease Term | Human Homologs | Mouse Homologs | Mouse Models | Homology Source | |||
inflammatory bowel disease | IL10* | Il10* | 3 models | Alliance of Genome Resources | |||
inflammatory bowel disease 10 | ATG16L1* | Atg16l1* | 2 models | Alliance of Genome Resources | |||
inflammatory bowel disease 13 | ABCB1* | Abcb1a*, Abcb1b | 1 model | Alliance of Genome Resources | |||
Crohn's disease | EFS | Efs* | 1 model | Alliance of Genome Resources | |||
Crohn's disease | PIKFYVE | Pikfyve* | 1 model | Alliance of Genome Resources | |||
inflammatory bowel disease | CD40LG | Cd40lg* | 1 model | Alliance of Genome Resources | |||
inflammatory bowel disease | IL2 | Il2* | 2 models | Alliance of Genome Resources | |||
inflammatory bowel disease | IL2RA | Il2ra* | 1 model | Alliance of Genome Resources | |||
inflammatory bowel disease | MUC2 | Muc2* | 3 models | Alliance of Genome Resources | |||
inflammatory bowel disease | NFIL3 | Nfil3* | 1 model | Alliance of Genome Resources | |||
inflammatory bowel disease | RUNX3 | Runx3* | 1 model | Alliance of Genome Resources | |||
inflammatory bowel disease | ST6GALNAC1 | St6galnac1* | 1 model | Alliance of Genome Resources | |||
inflammatory bowel disease | STAT3 | Stat3* | 3 models | Alliance of Genome Resources | |||
inflammatory bowel disease | TNF | Tnf* | 4 models | Alliance of Genome Resources | |||
inflammatory bowel disease | XBP1 | Xbp1* | 1 model | Alliance of Genome Resources | |||
inflammatory bowel disease 1 | NOD2 | Nod2* | 1 model | Alliance of Genome Resources | |||
inflammatory bowel disease 12 | GNAI2 | Gnai2* | 3 models | Alliance of Genome Resources | |||
inflammatory bowel disease 16 | TNFSF15 | Tnfsf15* | 2 models | Alliance of Genome Resources | |||
chemical colitis | SERPINA1* | Serpina1a, Serpina1b, Serpina1c, Serpina1d, Serpina1e | Alliance of Genome Resources | ||||
colitis | HLA-B*, HLA-A, HLA-C, HLA-E, HLA-F, HLA-G, HLA-H | H2-D1, H2-K1, H2-L, H2-M1, H2-M2, H2-M3, H2-M5, H2-M9, H2-M10.1, H2-M10.2, H2-M10.3, H2-M10.4, H2-M10.5, H2-M10.6, H2-M11, H2-Q1, H2-Q2, H2-Q4, H2-Q6, H2-Q7, H2-Q8, H2-Q10, H2-T3, H2-T10, H2-T22, H2-T23 | Alliance of Genome Resources | ||||
colitis | APOA4* | Apoa4 | Alliance of Genome Resources | ||||
Crohn's disease | OCLN* | Ocln | Alliance of Genome Resources | ||||
Crohn's disease | NOD2* | Nod2 | Alliance of Genome Resources | ||||
Crohn's disease | MKI67* | Mki67 | Alliance of Genome Resources | ||||
Crohn's disease | MBL2* | Mbl2 | Alliance of Genome Resources | ||||
Crohn's disease | LRRK2* | Lrrk2 | Alliance of Genome Resources | ||||
Crohn's disease | JAK2* | Jak2 | Alliance of Genome Resources | ||||
Crohn's disease | IL23R* | Il23r | Alliance of Genome Resources | ||||
Crohn's disease | IL21R* | Il21r | Alliance of Genome Resources | ||||
Crohn's disease | IL10* | Il10 | Alliance of Genome Resources | ||||
Crohn's disease | IL6* | Il6 | Alliance of Genome Resources | ||||
Crohn's disease | ICAM1* | Icam1 | Alliance of Genome Resources | ||||
Crohn's disease | HLA-DPA1* | ||||||
Crohn's disease | HFE* | Hfe | Alliance of Genome Resources | ||||
Crohn's disease | HLA-DQB1*, HLA-DQB2 | H2-Ab1 | Alliance of Genome Resources | ||||
Crohn's disease | GSTT1* | Gstt1 | Alliance of Genome Resources | ||||
Crohn's disease | GSTM1*, GSTM5 | Gstm1, Gstm2, Gstm3, Gstm6 | Alliance of Genome Resources | ||||
Crohn's disease | ABCB1* | Abcb1a, Abcb1b | Alliance of Genome Resources | ||||
Crohn's disease | BPI* | Bpi | Alliance of Genome Resources | ||||
Crohn's disease | CD40* | Cd40 | Alliance of Genome Resources | ||||
Crohn's disease | CLDN1* | Cldn1 | Alliance of Genome Resources | ||||
Crohn's disease | FCGR2A*, FCGR2B, FCGR2C | Fcgr2b, Fcgr3 | Alliance of Genome Resources | ||||
Crohn's disease | FCGR3A*, FCGR3B | Fcgr4 | Alliance of Genome Resources | ||||
Crohn's disease | GC* | Gc | Alliance of Genome Resources | ||||
Crohn's disease | SLC22A5* | Slc22a5, Slc22a21 | Alliance of Genome Resources | ||||
Crohn's disease | SLC11A1* | Slc11a1 | Alliance of Genome Resources | ||||
Crohn's disease | SELL* | Sell | Alliance of Genome Resources | ||||
Crohn's disease | UGT1A1* | Ugt1a1 | Alliance of Genome Resources | ||||
Crohn's disease | STAT3* | Stat3 | Alliance of Genome Resources | ||||
Crohn's disease | PTPN22* | Ptpn22 | Alliance of Genome Resources | ||||
Crohn's disease | PRF1* | Prf1 | Alliance of Genome Resources | ||||
ileitis | SERPINA1* | Serpina1a, Serpina1b, Serpina1c, Serpina1d, Serpina1e | Alliance of Genome Resources | ||||
inflammatory bowel disease | EGFR* | Egfr | Alliance of Genome Resources | ||||
inflammatory bowel disease | ADAM17* | Adam17 | Alliance of Genome Resources | ||||
inflammatory bowel disease | AGT* | Agt | Alliance of Genome Resources | ||||
inflammatory bowel disease | ALPI*, ALPG, ALPP | Akp3, Alpi, Alppl2 | Alliance of Genome Resources | ||||
inflammatory bowel disease | ANO6* | Ano6 | Alliance of Genome Resources | ||||
inflammatory bowel disease | B2M* | B2m | 1 model | Alliance of Genome Resources | |||
inflammatory bowel disease | CRP* | Crp | Alliance of Genome Resources | ||||
inflammatory bowel disease | GSTM1*, GSTM5 | Gstm1, Gstm2, Gstm3, Gstm6 | Alliance of Genome Resources | ||||
inflammatory bowel disease | GSTT1* | Gstt1 | Alliance of Genome Resources | ||||
inflammatory bowel disease | ICAM1* | Icam1 | Alliance of Genome Resources | ||||
inflammatory bowel disease | IGFBP3* | Igfbp3 | Alliance of Genome Resources | ||||
inflammatory bowel disease | IL1RN* | Il1rn | Alliance of Genome Resources | ||||
inflammatory bowel disease | IL33* | Il33 | Alliance of Genome Resources | ||||
inflammatory bowel disease | IL37* | ||||||
inflammatory bowel disease | MTHFR* | Mthfr | Alliance of Genome Resources | ||||
inflammatory bowel disease | NPSR1* | Npsr1 | Alliance of Genome Resources | ||||
inflammatory bowel disease | SLC11A1* | Slc11a1 | Alliance of Genome Resources | ||||
inflammatory bowel disease | TGFB1* | Tgfb1 | Alliance of Genome Resources | ||||
inflammatory bowel disease 14 | IRF5* | Irf5 | Alliance of Genome Resources | ||||
inflammatory bowel disease 17 | IL23R* | Il23r | Alliance of Genome Resources | ||||
inflammatory bowel disease 19 | IRGM* | Igtp, Irgm1, Irgm2 | Alliance of Genome Resources | ||||
inflammatory bowel disease 25 | IL10RB* | Il10rb | Alliance of Genome Resources | ||||
inflammatory bowel disease 28 | IL10RA* | Il10ra | Alliance of Genome Resources | ||||
inflammatory bowel disease 29 | INAVA* | Inava | Alliance of Genome Resources | ||||
inflammatory bowel disease 30 | CARD8* | ||||||
ischemic colitis | SERPINE1* | Serpine1 | Alliance of Genome Resources | ||||
ulcerative colitis | SELL* | Sell | Alliance of Genome Resources | ||||
ulcerative colitis | PTGER4* | Ptger4 | Alliance of Genome Resources | ||||
ulcerative colitis | JAK2* | Jak2 | Alliance of Genome Resources | ||||
ulcerative colitis | MTRR* | Mtrr | Alliance of Genome Resources | ||||
ulcerative colitis | IL23R* | Il23r | Alliance of Genome Resources | ||||
ulcerative colitis | IL1RN* | Il1rn | Alliance of Genome Resources | ||||
ulcerative colitis | HLA-DQB1*, HLA-DQB2 | H2-Ab1 | Alliance of Genome Resources | ||||
ulcerative colitis | GSTT1* | Gstt1 | Alliance of Genome Resources | ||||
ulcerative colitis | GSTM1*, GSTM5 | Gstm1, Gstm2, Gstm3, Gstm6 | Alliance of Genome Resources | ||||
ulcerative colitis | GC* | Gc | Alliance of Genome Resources | ||||
ulcerative colitis | FCGR2A*, FCGR2B, FCGR2C | Fcgr2b, Fcgr3 | Alliance of Genome Resources | ||||
ulcerative colitis | CYP24A1* | Cyp24a1 | Alliance of Genome Resources | ||||
ulcerative colitis | BTNL2* | Btnl2 | Alliance of Genome Resources | ||||
ulcerative colitis | APOA4* | Apoa4 | Alliance of Genome Resources | ||||
ulcerative colitis | ABCB1* | Abcb1a, Abcb1b | Alliance of Genome Resources | ||||
ulcerative colitis | STAT3* | Stat3 | Alliance of Genome Resources | ||||
ulcerative colitis | SLC11A1* | Slc11a1 | Alliance of Genome Resources |
Transgenes and other genome features developed in mice to model this disease.
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Disease Term | Transgenes and Other Genome Features | Mouse Models | |
inflammatory bowel disease | Tcra | 2 models | |
inflammatory bowel disease | Tg(Igh-V-CD40lg)#Tsub | 1 model | |
inflammatory bowel disease 16 | Tg(Lck-Tnfsf15,-EGFP)#Targ | 1 model | |
inflammatory bowel disease 16 | Tg(Csf1r-Tnfsf15,-EGFP)#Targ | 1 model |