| Disease Term | Human Homologs | Mouse Homologs | Mouse Models | Homology Source | |||
  | autoimmune polyendocrine syndrome type 1 | AIRE* | Aire* | 9 models | Alliance of Genome Resources | ||
| type 1 diabetes mellitus | CD38* | Cd38* | 1 model | Alliance of Genome Resources | |||
| type 1 diabetes mellitus | GAD2* | Gad2* | 1 model | Alliance of Genome Resources | |||
| type 1 diabetes mellitus | IL1R1* | Il1r1* | 1 model | Alliance of Genome Resources | |||
| type 1 diabetes mellitus | INS* | Ins2*, Ins1 | 6 models | Alliance of Genome Resources | |||
| type 1 diabetes mellitus | PTPRN2* | Ptprn2* | 1 model | Alliance of Genome Resources | |||
| | type 1 diabetes mellitus | CDK4 | Cdk4* | 1 model | Alliance of Genome Resources | ||
| type 1 diabetes mellitus | E2F1 | E2f1* | 1 model | Alliance of Genome Resources | |||
| type 1 diabetes mellitus | FASLG | Fasl* | 3 models | Alliance of Genome Resources | |||
| type 1 diabetes mellitus | G6PC2 | G6pc2* | 1 model | Alliance of Genome Resources | |||
| type 1 diabetes mellitus | IFNG | Ifng* | 2 models | Alliance of Genome Resources | |||
| type 1 diabetes mellitus | IFNGR2 | Ifngr2* | 1 model | Alliance of Genome Resources | |||
| type 1 diabetes mellitus | IGHM | Ighm* | 5 models | Alliance of Genome Resources | |||
| type 1 diabetes mellitus | IL4 | Il4* | 2 models | Alliance of Genome Resources | |||
| type 1 diabetes mellitus | IRAK3 | Irak3* | 1 model | Alliance of Genome Resources | |||
| type 1 diabetes mellitus | MBD2 | Mbd2* | 1 model | Alliance of Genome Resources | |||
| type 1 diabetes mellitus | NOS2 | Nos2* | 5 models | Alliance of Genome Resources | |||
| type 1 diabetes mellitus | PDX1 | Pdx1* | 1 model | Alliance of Genome Resources | |||
| type 1 diabetes mellitus | PRF1 | Prf1* | 2 models | Alliance of Genome Resources | |||
| type 1 diabetes mellitus | SELL | Sell* | 4 models | Alliance of Genome Resources | |||
| type 1 diabetes mellitus | SENP1 | Senp1* | 1 model | Alliance of Genome Resources | |||
| type 1 diabetes mellitus | STAT4 | Stat4* | 4 models | Alliance of Genome Resources | |||
| type 1 diabetes mellitus | TNFSF4 | Tnfsf4* | 1 model | Alliance of Genome Resources | |||
| type 1 diabetes mellitus 2 | IGF2 | Igf2* | 3 models | Alliance of Genome Resources | |||
| type 1 diabetes mellitus 7 | NEUROD1 | Neurod1* | 1 model | Alliance of Genome Resources | |||
| | autoimmune pancreatitis | HLA-DQB1*, HLA-DQB2 | H2-Ab1 | Alliance of Genome Resources | |||
| autoimmune polyendocrine syndrome | HLA-DRB1*, HLA-DRB3, HLA-DRB4, HLA-DRB5 | H2-Eb1, H2-Eb2 | Alliance of Genome Resources | ||||
| autoimmune polyendocrine syndrome | AIRE* | Aire | Alliance of Genome Resources | ||||
| autoimmune polyendocrine syndrome | HLA-DQA1*, HLA-DQA2 | H2-Aa | Alliance of Genome Resources | ||||
| autoimmune polyendocrine syndrome | HLA-DQB1*, HLA-DQB2 | H2-Ab1 | Alliance of Genome Resources | ||||
| autoimmune polyendocrine syndrome type 1 | GH1*, CSH1, CSH2, CSHL1, GH2 | Gh | Alliance of Genome Resources | ||||
| autoimmune polyendocrine syndrome type 1 | GHRH* | Ghrh | Alliance of Genome Resources | ||||
| autoimmune polyendocrine syndrome type 2 | HLA-DQB1*, HLA-DQB2 | H2-Ab1 | Alliance of Genome Resources | ||||
| autoimmune polyendocrine syndrome type 2 | HLA-DQA1*, HLA-DQA2 | H2-Aa | Alliance of Genome Resources | ||||
| autoimmune polyendocrine syndrome type 2 | HLA-DRB1*, HLA-DRB3, HLA-DRB4, HLA-DRB5 | H2-Eb1, H2-Eb2 | Alliance of Genome Resources | ||||
| autoimmune thyroiditis | PSMB9* | Psmb9 | Alliance of Genome Resources | ||||
| autoimmune thyroiditis | CTLA4* | Ctla4 | Alliance of Genome Resources | ||||
| autoimmune thyroiditis | HLA-DQA1*, HLA-DQA2 | H2-Aa | Alliance of Genome Resources | ||||
| autoimmune thyroiditis | ZFAT* | Zfat | Alliance of Genome Resources | ||||
| autoimmune thyroiditis | TG* | Tg | Alliance of Genome Resources | ||||
| autoimmune thyroiditis | PTPN22* | Ptpn22 | Alliance of Genome Resources | ||||
| autoimmune thyroiditis | HLA-DRA* | H2-Ea | Alliance of Genome Resources | ||||
| autoimmune thyroiditis | HLA-DRB1*, HLA-DRB3, HLA-DRB4, HLA-DRB5 | H2-Eb1, H2-Eb2 | Alliance of Genome Resources | ||||
| autoimmune thyroiditis | LRP2* | Lrp2 | Alliance of Genome Resources | ||||
| autoimmune thyroiditis | MBL2* | Mbl2 | Alliance of Genome Resources | ||||
| autoimmune thyroiditis | HLA-DQB1*, HLA-DQB2 | H2-Ab1 | Alliance of Genome Resources | ||||
| autoimmune thyroiditis | BANK1* | Bank1 | Alliance of Genome Resources | ||||
| Graves' disease | IL10* | Il10 | Alliance of Genome Resources | ||||
| Graves' disease | IL13* | Il13 | Alliance of Genome Resources | ||||
| Graves' disease | IL17A* | Il17a | Alliance of Genome Resources | ||||
| Graves' disease | IL23R* | Il23r | Alliance of Genome Resources | ||||
| Graves' disease | LTA* | Lta | Alliance of Genome Resources | ||||
| Graves' disease | MTHFR* | Mthfr | Alliance of Genome Resources | ||||
| Graves' disease | OGG1* | Ogg1 | Alliance of Genome Resources | ||||
| Graves' disease | PTPN22* | Ptpn22 | Alliance of Genome Resources | ||||
| Graves' disease | SERPINE1* | Serpine1 | Alliance of Genome Resources | ||||
| Graves' disease | TG* | Tg | Alliance of Genome Resources | ||||
| Graves' disease | TNF* | Tnf | Alliance of Genome Resources | ||||
| Graves' disease | TP53* | Trp53 | Alliance of Genome Resources | ||||
| Graves' disease | TSHR* | Tshr | Alliance of Genome Resources | ||||
| Graves' disease | VDR* | Vdr | Alliance of Genome Resources | ||||
| Graves' disease | VEGFA* | Vegfa | Alliance of Genome Resources | ||||
| Graves' disease | ADRB2* | Adrb2 | Alliance of Genome Resources | ||||
| Graves' disease | BTNL2* | Btnl2 | Alliance of Genome Resources | ||||
| Graves' disease | C4A*, C4B*, C4B_2 | C4a, C4b | Alliance of Genome Resources | ||||
| Graves' disease | CD40* | Cd40 | Alliance of Genome Resources | ||||
| Graves' disease | CD40LG* | Cd40lg | Alliance of Genome Resources | ||||
| Graves' disease | CTLA4* | Ctla4 | Alliance of Genome Resources | ||||
| Graves' disease | CYP1A1* | Cyp1a1 | Alliance of Genome Resources | ||||
| Graves' disease | DNMT1* | Dnmt1 | Alliance of Genome Resources | ||||
| Graves' disease | ESR2* | Esr2 | Alliance of Genome Resources | ||||
| Graves' disease | FKBP1B* | Fkbp1b | Alliance of Genome Resources | ||||
| Graves' disease | GC* | Gc | Alliance of Genome Resources | ||||
| Graves' disease | GSTP1* | Gstp1, Gstp2, Gstp3, Gstp-ps | Alliance of Genome Resources | ||||
| Graves' disease | HLA-DQA1*, HLA-DQA2 | H2-Aa | Alliance of Genome Resources | ||||
| Graves' disease | HLA-DQB1*, HLA-DQB2 | H2-Ab1 | Alliance of Genome Resources | ||||
| Graves' disease | HLA-B*, HLA-A, HLA-C, HLA-E, HLA-F, HLA-G, HLA-H | H2-D1, H2-K1, H2-L, H2-M1, H2-M2, H2-M3, H2-M5, H2-M9, H2-M10.1, H2-M10.2, H2-M10.3, H2-M10.4, H2-M10.5, H2-M10.6, H2-M11, H2-Q1, H2-Q2, H2-Q4, H2-Q6, H2-Q7, H2-Q8, H2-Q10, H2-T3, H2-T10, H2-T22, H2-T23 | Alliance of Genome Resources | ||||
| Graves' disease | HLA-DRB1*, HLA-DRB3*, HLA-DRB4, HLA-DRB5 | H2-Eb1, H2-Eb2 | Alliance of Genome Resources | ||||
| Graves' disease | ICAM1* | Icam1 | Alliance of Genome Resources | ||||
| Graves' disease | IFNG* | Ifng | Alliance of Genome Resources | ||||
| Graves' disease | IL1B* | Il1b | Alliance of Genome Resources | ||||
| Graves' disease | IL2* | Il2 | Alliance of Genome Resources | ||||
| Graves' disease | IL3* | Il3 | Alliance of Genome Resources | ||||
| Graves' disease | IL6* | Il6 | Alliance of Genome Resources | ||||
| latent autoimmune diabetes in adults | CTLA4* | Ctla4 | Alliance of Genome Resources | ||||
| type 1 diabetes mellitus | ACE* | Ace | Alliance of Genome Resources | ||||
| type 1 diabetes mellitus | ACP1* | Acp1 | Alliance of Genome Resources | ||||
| type 1 diabetes mellitus | AGER* | Ager | 1 model | Alliance of Genome Resources | |||
| type 1 diabetes mellitus | AIF1* | Aif1 | Alliance of Genome Resources | ||||
| type 1 diabetes mellitus | ALDH2* | Aldh2 | Alliance of Genome Resources | ||||
| type 1 diabetes mellitus | APOC3* | Apoc3 | Alliance of Genome Resources | ||||
| type 1 diabetes mellitus | APOM* | Apom | Alliance of Genome Resources | ||||
| type 1 diabetes mellitus | BANK1* | Bank1 | Alliance of Genome Resources | ||||
| type 1 diabetes mellitus | BCHE* | Bche | Alliance of Genome Resources | ||||
| type 1 diabetes mellitus | BTC* | Btc | Alliance of Genome Resources | ||||
| type 1 diabetes mellitus | CBLB* | Cblb | Alliance of Genome Resources | ||||
| type 1 diabetes mellitus | CCL5* | Ccl5 | Alliance of Genome Resources | ||||
| type 1 diabetes mellitus | CCR2* | Ccr2 | Alliance of Genome Resources | ||||
| type 1 diabetes mellitus | CD28* | Cd28 | Alliance of Genome Resources | ||||
| type 1 diabetes mellitus | CD80* | Cd80 | 2 models | Alliance of Genome Resources | |||
| type 1 diabetes mellitus | CD86* | Cd86 | 1 model | Alliance of Genome Resources | |||
| type 1 diabetes mellitus | CEL* | Cel | Alliance of Genome Resources | ||||
| type 1 diabetes mellitus | CFB* | Cfb | Alliance of Genome Resources | ||||
| type 1 diabetes mellitus | CLEC16A* | Clec16a | Alliance of Genome Resources | ||||
| type 1 diabetes mellitus | CTLA4* | Ctla4 | Alliance of Genome Resources | ||||
| type 1 diabetes mellitus | CXCL12* | Cxcl12 | Alliance of Genome Resources | ||||
| type 1 diabetes mellitus | CYP2R1* | Cyp2r1 | Alliance of Genome Resources | ||||
| type 1 diabetes mellitus | CYP27B1* | Cyp27b1 | Alliance of Genome Resources | ||||
| type 1 diabetes mellitus | DDX39B* | Ddx39b | Alliance of Genome Resources | ||||
| type 1 diabetes mellitus | EIF2AK3* | Eif2ak3 | Alliance of Genome Resources | ||||
| type 1 diabetes mellitus | ETS1* | Ets1 | Alliance of Genome Resources | ||||
| type 1 diabetes mellitus | F7* | F7 | Alliance of Genome Resources | ||||
| type 1 diabetes mellitus | FOXP3* | Foxp3 | Alliance of Genome Resources | ||||
| type 1 diabetes mellitus | GC* | Gc | Alliance of Genome Resources | ||||
| type 1 diabetes mellitus | GH1*, CSH1, CSH2, CSHL1, GH2 | Gh | Alliance of Genome Resources | ||||
| type 1 diabetes mellitus | GSTM1*, GSTM5 | Gstm1, Gstm2, Gstm3, Gstm6 | Alliance of Genome Resources | ||||
| type 1 diabetes mellitus | HLA-DQA1*, HLA-DQA2 | H2-Aa | Alliance of Genome Resources | ||||
| type 1 diabetes mellitus | HLA-DQB1*, HLA-DQB2 | H2-Ab1 | 3 models | Alliance of Genome Resources | |||
| type 1 diabetes mellitus | HLA-DRB1*, HLA-DRB3, HLA-DRB4, HLA-DRB5 | H2-Eb1, H2-Eb2 | Alliance of Genome Resources | ||||
| type 1 diabetes mellitus | HLA-DPA1* | ||||||
| type 1 diabetes mellitus | HLA-DPB1* | ||||||
| type 1 diabetes mellitus | HNF1A* | Hnf1a | Alliance of Genome Resources | ||||
| type 1 diabetes mellitus | HSD11B2* | Hsd11b2 | Alliance of Genome Resources | ||||
| type 1 diabetes mellitus | IAPP* | Iapp | Alliance of Genome Resources | ||||
| type 1 diabetes mellitus | ICA1* | Ica1 | Alliance of Genome Resources | ||||
| type 1 diabetes mellitus | ICAM1* | Icam1 | 1 "NOT" model | Alliance of Genome Resources | |||
| type 1 diabetes mellitus | IGF1* | Igf1 | Alliance of Genome Resources | ||||
| type 1 diabetes mellitus | IGF2R* | Igf2r | Alliance of Genome Resources | ||||
| type 1 diabetes mellitus | IGFBP3* | Igfbp3 | Alliance of Genome Resources | ||||
| type 1 diabetes mellitus | IL1A* | Il1a | Alliance of Genome Resources | ||||
| type 1 diabetes mellitus | IL1B* | Il1b | Alliance of Genome Resources | ||||
| type 1 diabetes mellitus | IL1RN* | Il1rn | Alliance of Genome Resources | ||||
| type 1 diabetes mellitus | IL2* | Il2 | Alliance of Genome Resources | ||||
| type 1 diabetes mellitus | IL2RA* | Il2ra | Alliance of Genome Resources | ||||
| type 1 diabetes mellitus | IL6* | Il6 | Alliance of Genome Resources | ||||
| type 1 diabetes mellitus | IL15* | Il15 | Alliance of Genome Resources | ||||
| type 1 diabetes mellitus | ISL1* | Isl1 | Alliance of Genome Resources | ||||
| type 1 diabetes mellitus | ITPR3* | Itpr3 | Alliance of Genome Resources | ||||
| type 1 diabetes mellitus | LTA* | Lta | Alliance of Genome Resources | ||||
| type 1 diabetes mellitus | MIR146A* | Mir146 | Alliance of Genome Resources | ||||
| type 1 diabetes mellitus | MIR155* | Mir155 | Alliance of Genome Resources | ||||
| type 1 diabetes mellitus | MTHFR* | Mthfr | Alliance of Genome Resources | ||||
| type 1 diabetes mellitus | NEUROD1* | Neurod1 | Alliance of Genome Resources | ||||
| type 1 diabetes mellitus | NOTCH4* | Notch4 | Alliance of Genome Resources | ||||
| type 1 diabetes mellitus | PAX4* | Pax4 | Alliance of Genome Resources | ||||
| type 1 diabetes mellitus | PRRC2A* | Prrc2a | Alliance of Genome Resources | ||||
| type 1 diabetes mellitus | PTH* | Pth | Alliance of Genome Resources | ||||
| type 1 diabetes mellitus | PTPN22* | Ptpn22 | Alliance of Genome Resources | ||||
| type 1 diabetes mellitus | PTPRN* | Ptprn | Alliance of Genome Resources | ||||
| type 1 diabetes mellitus | RAN* | Ran | Alliance of Genome Resources | ||||
| type 1 diabetes mellitus | REG1A*, REG1B | Reg1, Reg2 | Alliance of Genome Resources | ||||
| type 1 diabetes mellitus | SH2B3* | Sh2b3 | Alliance of Genome Resources | ||||
| type 1 diabetes mellitus | SLC11A1* | Slc11a1 | Alliance of Genome Resources | ||||
| type 1 diabetes mellitus | SOD1* | Sod1 | Alliance of Genome Resources | ||||
| type 1 diabetes mellitus | SOD2* | Sod2 | Alliance of Genome Resources | ||||
| type 1 diabetes mellitus | SREBF2* | Srebf2 | Alliance of Genome Resources | ||||
| type 1 diabetes mellitus | TAP1* | Tap1 | Alliance of Genome Resources | ||||
| type 1 diabetes mellitus | TAP2* | Tap2 | Alliance of Genome Resources | ||||
| type 1 diabetes mellitus | TBP* | Tbp | Alliance of Genome Resources | ||||
| type 1 diabetes mellitus | TLR2* | Tlr2 | 1 "NOT" model | Alliance of Genome Resources | |||
| type 1 diabetes mellitus | TLR3* | Tlr3 | Alliance of Genome Resources | ||||
| type 1 diabetes mellitus | TNF* | Tnf | Alliance of Genome Resources | ||||
| type 1 diabetes mellitus | TF* | Trf | Alliance of Genome Resources | ||||
| type 1 diabetes mellitus | WFS1* | Wfs1 | Alliance of Genome Resources | ||||
| type 1 diabetes mellitus | XYLT1* | Xylt1 | Alliance of Genome Resources | ||||
| type 1 diabetes mellitus 10 | IL2RA* | Il2ra | Alliance of Genome Resources | ||||
| type 1 diabetes mellitus 12 | CTLA4* | Ctla4 | Alliance of Genome Resources | ||||
| type 1 diabetes mellitus 2 | INS* | Ins1, Ins2 | Alliance of Genome Resources | ||||
| type 1 diabetes mellitus 20 | HNF1A* | Hnf1a | Alliance of Genome Resources | ||||
| type 1 diabetes mellitus 22 | CCR5* | Ccr5 | Alliance of Genome Resources | ||||
| type 1 diabetes mellitus 5 | SUMO4* | ||||||
Excel File
|
Transgenes and other genome features developed in mice to model this disease.
|
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| Disease Term | Transgenes and Other Genome Features | Mouse Models | |
| type 1 diabetes mellitus | H2-I | 1 model | |
| type 1 diabetes mellitus | Tcra | 13 models | |
| type 1 diabetes mellitus | Tg(Cryaa-TAg,Ins2-CALM1)26Ove | 2 models | |
| type 1 diabetes mellitus | Tg(H2-Ea-G6pc2)69Tkay | 1 model | |
| type 1 diabetes mellitus | Tg(H2-Ea-Ins2)1Wehi | 1 model | |
| type 1 diabetes mellitus | Tg(H2-Ead)12Lt | 1 model | |
| type 1 diabetes mellitus | Tg(HLA-A/H2-D/B2M)1Dvs | 2 models | |
| type 1 diabetes mellitus | Tg(Igh-6/Igh-V281)3Jwt | 2 models | |
| type 1 diabetes mellitus | Tg(Igh-VB1-8/Igh-6m)1Mjsk | 1 model | |
| type 1 diabetes mellitus | Tg(IghelMD4)4Ccg | 1 model | |
| type 1 diabetes mellitus | Tg(Ins1-Cat,Tyr)25Pne | 2 models | |
| type 1 diabetes mellitus | Tg(Ins2*Y16A)3Ell | 1 model | |
| type 1 diabetes mellitus | Tg(Ins2-CD80)3B7Flv | 4 models | |
| type 1 diabetes mellitus | Tg(Ins2-Fasl)24Ach | 3 models | |
| type 1 diabetes mellitus | Tg(Ins2-GP)34-20Olds | 2 models | |
| type 1 diabetes mellitus | Tg(Ins2-HBEGF)5Rin | 1 model | |
| type 1 diabetes mellitus | Tg(Ins2-Nos2)31Okam | 1 model | |
| type 1 diabetes mellitus | Tg(Ins2-Nos2)40Okam | 4 models | |
| type 1 diabetes mellitus | Tg(Ins2-NP)25-3Olds | 2 models | |
| type 1 diabetes mellitus | Tg(INS-MT2A,Tyr)1Pne | 2 models | |
| type 1 diabetes mellitus | Tg(INS-SOD2)3Pne | 1 model | |
| type 1 diabetes mellitus | Tg(TcraAI4)1Dvs | 5 models | |
| type 1 diabetes mellitus | Tg(TcraTcrbNY8.3)1Pesa | 1 model | |
| type 1 diabetes mellitus 2 | Tg(Ins-Igf2)1Fbos | 3 models | |