| Disease Term | Human Homologs | Mouse Homologs | Mouse Models | Homology Source | |||
  | B-cell lymphoma | EZH2* | Ezh2* | 1 model | Alliance of Genome Resources | ||
| Burkitt lymphoma | MYC* | Myc*, Bmyc | 4 models | Alliance of Genome Resources | |||
| | diffuse large B-cell lymphoma | TP53 | Trp53* | 2 models | Alliance of Genome Resources | ||
| diffuse large B-cell lymphoma | SMURF2 | Smurf2* | 1 model | Alliance of Genome Resources | |||
| follicular lymphoma | RARRES1 | Rarres1* | 3 models | Alliance of Genome Resources | |||
| lymphoma | MIR155 | Mir155* | 1 model | Alliance of Genome Resources | |||
| lymphoma | HMGA1 | Hmga1*, Hmga1b | 1 model | Alliance of Genome Resources | |||
| non-Hodgkin lymphoma | MTSS1 | Mtss1* | 1 model | Alliance of Genome Resources | |||
| non-Hodgkin lymphoma | S1PR2 | S1pr2* | 2 models | Alliance of Genome Resources | |||
| peripheral T-cell lymphoma | RC3H1 | Rc3h1* | 1 model | Alliance of Genome Resources | |||
| T-cell acute lymphoblastic leukemia | HMGA1 | Hmga1*, Hmga1b | 1 model | Alliance of Genome Resources | |||
| T-cell acute lymphoblastic leukemia | NBN | Nbn* | 1 model | Alliance of Genome Resources | |||
| T-cell adult acute lymphocytic leukemia | CNTN2 | Cntn2* | 1 model | Alliance of Genome Resources | |||
| T-cell adult acute lymphocytic leukemia | ZEB2 | Zeb2* | 2 models | Alliance of Genome Resources | |||
| | acute biphenotypic leukemia | DOT1L* | Dot1l | Alliance of Genome Resources | |||
| adenoid cystic carcinoma | KDM6A* | Kdm6a | Alliance of Genome Resources | ||||
| adenoid cystic carcinoma | KMT2C* | Kmt2c | Alliance of Genome Resources | ||||
| adenoid cystic carcinoma | NTRK3* | Ntrk3 | Alliance of Genome Resources | ||||
| adenoid cystic carcinoma | XRN2* | Xrn2 | Alliance of Genome Resources | ||||
| adenoid cystic carcinoma | ATR* | Atr | Alliance of Genome Resources | ||||
| adult T-cell leukemia/lymphoma | JAK3* | Jak3 | Alliance of Genome Resources | ||||
| adult T-cell leukemia/lymphoma | FAS* | Fas | Alliance of Genome Resources | ||||
| adult T-cell leukemia/lymphoma | TLX1* | Tlx1 | Alliance of Genome Resources | ||||
| adult T-cell leukemia/lymphoma | TAL2* | Tal2 | Alliance of Genome Resources | ||||
| adult T-cell leukemia/lymphoma | NOTCH1* | Notch1 | Alliance of Genome Resources | ||||
| anaplastic large cell lymphoma | IRF4* | Irf4 | Alliance of Genome Resources | ||||
| B-cell lymphoma | CD40* | Cd40 | Alliance of Genome Resources | ||||
| B-cell lymphoma | BTK* | Btk | Alliance of Genome Resources | ||||
| B-cell lymphoma | BRD2* | Brd2 | Alliance of Genome Resources | ||||
| B-cell lymphoma | BCL6* | Bcl6 | Alliance of Genome Resources | ||||
| B-cell lymphoma | ABCG2* | Abcg2, Abcg3 | Alliance of Genome Resources | ||||
| B-cell lymphoma | IL21R* | Il21r | Alliance of Genome Resources | ||||
| B-lymphoblastic leukemia/lymphoma | CYP3A5*, CYP3A4, CYP3A7, CYP3A7-CYP3A51P, CYP3A43 | Cyp3a11, Cyp3a13, Cyp3a16, Cyp3a25, Cyp3a41a, Cyp3a41b, Cyp3a44, Cyp3a57, Cyp3a59 | Alliance of Genome Resources | ||||
| B-lymphoblastic leukemia/lymphoma | F3* | F3 | Alliance of Genome Resources | ||||
| B-lymphoblastic leukemia/lymphoma | IKZF1* | Ikzf1 | Alliance of Genome Resources | ||||
| B-lymphoblastic leukemia/lymphoma | TFPI* | Tfpi | Alliance of Genome Resources | ||||
| B-lymphoblastic leukemia/lymphoma | TNFSF13* | Tnfsf13 | Alliance of Genome Resources | ||||
| B-lymphoblastic leukemia/lymphoma | TP53* | Trp53 | Alliance of Genome Resources | ||||
| B-lymphoblastic leukemia/lymphoma | ABL1* | Abl1 | Alliance of Genome Resources | ||||
| B-lymphoblastic leukemia/lymphoma | AKR1C3*, AKR1C1, AKR1C2, AKR1C4 | Akr1c6, Akr1c12, Akr1c13, Akr1c14, Akr1c18, Akr1c19, Akr1c20, Akr1c21, Akr1cl | Alliance of Genome Resources | ||||
| B-lymphoblastic leukemia/lymphoma | BRD2* | Brd2 | Alliance of Genome Resources | ||||
| B-lymphoblastic leukemia/lymphoma | CDKN2A* | Cdkn2a | Alliance of Genome Resources | ||||
| Burkitt lymphoma | BTK* | Btk | Alliance of Genome Resources | ||||
| Burkitt lymphoma | CD79B* | Cd79b | Alliance of Genome Resources | ||||
| Burkitt lymphoma | CD40* | Cd40 | Alliance of Genome Resources | ||||
| Burkitt lymphoma | CALR* | Calr | Alliance of Genome Resources | ||||
| central nervous system lymphoma | IL10* | Il10 | Alliance of Genome Resources | ||||
| central nervous system lymphoma | BTK* | Btk | Alliance of Genome Resources | ||||
| central nervous system lymphoma | CD79B* | Cd79b | Alliance of Genome Resources | ||||
| central nervous system lymphoma | MYD88* | Myd88 | Alliance of Genome Resources | ||||
| chronic lymphocytic leukemia | CD79B* | Cd79b | Alliance of Genome Resources | ||||
| chronic lymphocytic leukemia | CD86* | Cd86 | Alliance of Genome Resources | ||||
| chronic lymphocytic leukemia | IRF4* | Irf4 | Alliance of Genome Resources | ||||
| chronic lymphocytic leukemia | PON1* | Pon1 | Alliance of Genome Resources | ||||
| chronic lymphocytic leukemia | PTPN22* | Ptpn22 | Alliance of Genome Resources | ||||
| diffuse large B-cell lymphoma | MYD88* | Myd88 | Alliance of Genome Resources | ||||
| diffuse large B-cell lymphoma | FCGR2A*, FCGR2B, FCGR2C | Fcgr2b, Fcgr3 | Alliance of Genome Resources | ||||
| diffuse large B-cell lymphoma | CD79B* | Cd79b | Alliance of Genome Resources | ||||
| diffuse large B-cell lymphoma | CD40* | Cd40 | Alliance of Genome Resources | ||||
| diffuse large B-cell lymphoma | GSTT1* | Gstt1 | Alliance of Genome Resources | ||||
| diffuse large B-cell lymphoma | BCL6* | Bcl6 | Alliance of Genome Resources | ||||
| diffuse large B-cell lymphoma | GSTP1* | Gstp1, Gstp2, Gstp3, Gstp-ps | Alliance of Genome Resources | ||||
| diffuse large B-cell lymphoma | GSTM1*, GSTM5 | Gstm1, Gstm2, Gstm3, Gstm6 | Alliance of Genome Resources | ||||
| diffuse large B-cell lymphoma | MTHFR* | Mthfr | Alliance of Genome Resources | ||||
| diffuse large B-cell lymphoma | IL21R* | Il21r | Alliance of Genome Resources | ||||
| diffuse large B-cell lymphoma | CD22* | Cd22 | Alliance of Genome Resources | ||||
| diffuse large B-cell lymphoma | CARD11* | Card11 | Alliance of Genome Resources | ||||
| extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue | HLA-DQA1*, HLA-DQA2 | H2-Aa | Alliance of Genome Resources | ||||
| extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue | BIRC3* | Birc3 | Alliance of Genome Resources | ||||
| extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue | BCL10* | Bcl10 | Alliance of Genome Resources | ||||
| follicular lymphoma | BCL2* | Bcl2 | Alliance of Genome Resources | ||||
| follicular lymphoma | CD40* | Cd40 | Alliance of Genome Resources | ||||
| follicular lymphoma | CD40LG* | Cd40lg | Alliance of Genome Resources | ||||
| follicular lymphoma | CD79B* | Cd79b | Alliance of Genome Resources | ||||
| follicular lymphoma | KDSR* | Kdsr | Alliance of Genome Resources | ||||
| hairy cell leukemia | GPX1* | Gpx1 | Alliance of Genome Resources | ||||
| Hodgkin's lymphoma | GSTT1* | Gstt1 | Alliance of Genome Resources | ||||
| Hodgkin's lymphoma | IL6* | Il6 | Alliance of Genome Resources | ||||
| Hodgkin's lymphoma | KLHDC8B* | Klhdc8b | Alliance of Genome Resources | ||||
| Hodgkin's lymphoma | NFKBIA* | Nfkbia | Alliance of Genome Resources | ||||
| Hodgkin's lymphoma | GSTM1*, GSTM5 | Gstm1, Gstm2, Gstm3, Gstm6 | Alliance of Genome Resources | ||||
| lymphoma | CHD4* | Chd4 | Alliance of Genome Resources | ||||
| lymphoma | MAD1L1* | Mad1l1 | Alliance of Genome Resources | ||||
| lymphoma | PSMB9* | Psmb9 | Alliance of Genome Resources | ||||
| lymphoma | MALT1* | Malt1 | Alliance of Genome Resources | ||||
| lymphoma | PAFAH1B2* | Pafah1b2 | Alliance of Genome Resources | ||||
| lymphoma | RELA* | Rela | Alliance of Genome Resources | ||||
| lymphoplasmacytic lymphoma | FCGR3A*, FCGR3B | Fcgr4 | Alliance of Genome Resources | ||||
| lymphoplasmacytic lymphoma | IL6* | Il6 | Alliance of Genome Resources | ||||
| lymphoplasmacytic lymphoma | IL10* | Il10 | Alliance of Genome Resources | ||||
| lymphoplasmacytic lymphoma | MYD88* | Myd88 | Alliance of Genome Resources | ||||
| lymphoplasmacytic lymphoma | CXCR4* | Cxcr4 | Alliance of Genome Resources | ||||
| mantle cell lymphoma | CD79B* | Cd79b | Alliance of Genome Resources | ||||
| mantle cell lymphoma | BTK* | Btk | Alliance of Genome Resources | ||||
| mantle cell lymphoma | CCDC50* | Ccdc50 | Alliance of Genome Resources | ||||
| mantle cell lymphoma | TNFRSF10A*, TNFRSF10B, TNFRSF10C, TNFRSF10D | Tnfrsf10b | Alliance of Genome Resources | ||||
| marginal zone lymphoma | HLA-DQB1*, HLA-DQB2 | H2-Ab1 | Alliance of Genome Resources | ||||
| marginal zone lymphoma | HLA-DQA1*, HLA-DQA2 | H2-Aa | Alliance of Genome Resources | ||||
| mature T-cell and NK-cell lymphoma | H19* | ||||||
| mycosis fungoides | HLA-DQB1*, HLA-DQB2 | H2-Ab1 | Alliance of Genome Resources | ||||
| nasal type extranodal NK/T-cell lymphoma | FAS* | Fas | Alliance of Genome Resources | ||||
| non-Hodgkin lymphoma | BCL10* | Bcl10 | Alliance of Genome Resources | ||||
| non-Hodgkin lymphoma | TMEM260* | Tmem260 | Alliance of Genome Resources | ||||
| non-Hodgkin lymphoma | RAD54L* | Rad54l | Alliance of Genome Resources | ||||
| non-Hodgkin lymphoma | RAD54B* | Rad54b | Alliance of Genome Resources | ||||
| non-Hodgkin lymphoma | PRF1* | Prf1 | Alliance of Genome Resources | ||||
| non-Hodgkin lymphoma | PON1* | Pon1 | Alliance of Genome Resources | ||||
| non-Hodgkin lymphoma | MTRR* | Mtrr | Alliance of Genome Resources | ||||
| non-Hodgkin lymphoma | MALT1* | Malt1 | Alliance of Genome Resources | ||||
| non-Hodgkin lymphoma | KMT2A* | Kmt2a | Alliance of Genome Resources | ||||
| non-Hodgkin lymphoma | GPX1* | Gpx1 | Alliance of Genome Resources | ||||
| non-Hodgkin lymphoma | FCGR2A*, FCGR2B, FCGR2C | Fcgr2b, Fcgr3 | Alliance of Genome Resources | ||||
| non-Hodgkin lymphoma | EPHX1* | Ephx1 | Alliance of Genome Resources | ||||
| non-Hodgkin lymphoma | CTLA4* | Ctla4 | Alliance of Genome Resources | ||||
| non-Hodgkin lymphoma | CD79B* | Cd79b | Alliance of Genome Resources | ||||
| non-Hodgkin lymphoma | CD40* | Cd40 | Alliance of Genome Resources | ||||
| non-Hodgkin lymphoma | CCND1* | Ccnd1 | Alliance of Genome Resources | ||||
| non-Hodgkin lymphoma | CASP10* | ||||||
| peripheral T-cell lymphoma | IRF4* | Irf4 | Alliance of Genome Resources | ||||
| plasma cell leukemia | CD40* | Cd40 | Alliance of Genome Resources | ||||
| plasmacytoma | ROBO1* | Robo1 | Alliance of Genome Resources | ||||
| plasmacytoma | BCL2* | Bcl2 | Alliance of Genome Resources | ||||
| primary cutaneous T-cell non-Hodgkin lymphoma | CDKN2A* | Cdkn2a | Alliance of Genome Resources | ||||
| primary cutaneous T-cell non-Hodgkin lymphoma | CDKN2B* | Cdkn2b | Alliance of Genome Resources | ||||
| T-cell acute lymphoblastic leukemia | DNMT3A* | Dnmt3a | Alliance of Genome Resources | ||||
| T-cell acute lymphoblastic leukemia | RPL5* | Rpl5 | Alliance of Genome Resources | ||||
| T-cell acute lymphoblastic leukemia | PDGFRA* | Pdgfra | Alliance of Genome Resources | ||||
| T-cell acute lymphoblastic leukemia | RPL11* | Rpl11 | Alliance of Genome Resources | ||||
| T-cell acute lymphoblastic leukemia | AKR1C3*, AKR1C1, AKR1C2, AKR1C4 | Akr1c6, Akr1c12, Akr1c13, Akr1c14, Akr1c18, Akr1c19, Akr1c20, Akr1c21, Akr1cl | Alliance of Genome Resources | ||||
| T-cell acute lymphoblastic leukemia | JAK3* | Jak3 | Alliance of Genome Resources | ||||
| T-cell acute lymphoblastic leukemia | JAK1* | Jak1 | Alliance of Genome Resources | ||||
| T-cell acute lymphoblastic leukemia | CDKN2A* | Cdkn2a | Alliance of Genome Resources | ||||
| T-cell acute lymphoblastic leukemia | CXCR4* | Cxcr4 | Alliance of Genome Resources | ||||
| T-cell acute lymphoblastic leukemia | LYL1* | Lyl1 | Alliance of Genome Resources | ||||
| T-cell acute lymphoblastic leukemia | NUP98* | Nup98 | Alliance of Genome Resources | ||||
| T-cell non-Hodgkin lymphoma | JAK3* | Jak3 | Alliance of Genome Resources | ||||
| T-cell non-Hodgkin lymphoma | FGFR1* | Fgfr1 | Alliance of Genome Resources | ||||
| T-cell non-Hodgkin lymphoma | TMEM260* | Tmem260 | Alliance of Genome Resources | ||||
| T-cell non-Hodgkin lymphoma | IER3* | Ier3 | Alliance of Genome Resources | ||||
| T-cell prolymphocytic leukemia | JAK3* | Jak3 | Alliance of Genome Resources | ||||
| testicular lymphoma | MYD88* | Myd88 | Alliance of Genome Resources | ||||
| thymoma | DNMT3B* | Dnmt3b | Alliance of Genome Resources | ||||
Excel File
|
Transgenes and other genome features developed in mice to model this disease.
|
|||
| Disease Term | Transgenes and Other Genome Features | Mouse Models | |
| Burkitt lymphoma | Tg(IghMyc)22Bri | 1 model | |
| Burkitt lymphoma | Tg(IGL-MYC)3Hm | 1 model | |
| chronic lymphocytic leukemia | Del(14Trim13-Rnaseh2b)6Rdf | 2 models | |
| chronic lymphocytic leukemia | Mirc30 | 6 models | |
| chronic lymphocytic leukemia | Tg(Igh-Mir29a,-Mir29b-1,-hrGFP)#Cro | 2 models | |
| chronic lymphocytic leukemia | Tg(Igh-ROR1)1Kip | 2 models | |
| chronic lymphocytic leukemia | Tg(Igh-TCL1A)1Ypek | 1 model | |
| chronic lymphocytic leukemia | Tg(Igh-V186.2-TCL1A)3Cro | 4 models | |
| chronic lymphocytic leukemia | Tg(Lck-TNFSF13)3919Mhah | 1 model | |
| chronic lymphocytic leukemia | Del(14Trim13-Dleu2)4Rdf | 2 models | |
| extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue | Tg(Ly6e-MALT1)#Isg | 1 model | |
| follicular lymphoma | Tg(Vav-BCL2)69Jad | 1 model | |
| lymphoma | Tg(Vav1-STAT5B*N642H)726Biat | 1 model | |
| lymphoma | Tg(H2-K-Hmga1)#Lmsr | 1 model | |
| non-Hodgkin lymphoma | Tg(EmuSR-HDAC9)1468Kpet | 1 model | |
| non-Hodgkin lymphoma | Tg(tetO-NPM1/ALK,-luc)2Gde | 1 model | |
| non-Hodgkin lymphoma | Tg(tetO-TPM3/ALK,-luc)2Gde | 1 model | |
| plasmacytoma | Tg(H2-L-IL6)46Kish | 1 model | |
| T-cell acute lymphoblastic leukemia | Tg(H2-K-Hmga1)#Lmsr | 1 model | |
| T-cell adult acute lymphocytic leukemia | Tg(Lck-Tax)53Hall | 1 model | |