Disease Term | Human Homologs | Mouse Homologs | Mouse Models | Homology Source | |||
arteriovenous malformations of the brain | ENG* | Eng* | 1 model | Alliance of Genome Resources | |||
arteriovenous malformations of the brain | KRAS* | Kras* | 2 models | Alliance of Genome Resources | |||
infantile myofibromatosis | PDGFRB* | Pdgfrb* | 1 model | Alliance of Genome Resources | |||
pheochromocytoma | RET* | Ret* | 1 model | Alliance of Genome Resources | |||
von Hippel-Lindau disease | VHL*, VHLL | Vhl* | 16 models | Alliance of Genome Resources | |||
arteriovenous malformations of the brain | ACVRL1 | Acvrl1* | 1 model | Alliance of Genome Resources | |||
arteriovenous malformations of the brain | NOTCH4 | Notch4* | 1 model | Alliance of Genome Resources | |||
dermoid cyst of ovary | FOXO3, FOXO3B | Foxo3* | 1 model | Alliance of Genome Resources | |||
epidermal appendage tumor | TMEM207 | Tmem207* | 1 model | Alliance of Genome Resources | |||
growth hormone secreting pituitary adenoma | MEN1 | Men1* | 1 model | Alliance of Genome Resources | |||
hepatocellular adenoma | PTPN11 | Ptpn11* | 1 model | Alliance of Genome Resources | |||
prolactinoma | MEN1 | Men1* | 1 model | Alliance of Genome Resources | |||
uterine fibroid | TSC2 | Tsc2* | 1 model | Alliance of Genome Resources | |||
acoustic neuroma | ERCC2* | Ercc2 | Alliance of Genome Resources | ||||
acoustic neuroma | VEGFA* | Vegfa | Alliance of Genome Resources | ||||
acoustic neuroma | CYP2E1* | Cyp2e1 | Alliance of Genome Resources | ||||
ACTH-secreting pituitary adenoma | USP8* | Usp8 | Alliance of Genome Resources | ||||
adrenal cortical adenoma | PRKACA* | Prkaca | Alliance of Genome Resources | ||||
angiokeratoma | NAGA* | Naga | Alliance of Genome Resources | ||||
appendiceal neoplasm | DAXX* | Daxx | Alliance of Genome Resources | ||||
arteriovenous malformation | GLMN* | Glmn | Alliance of Genome Resources | ||||
arteriovenous malformation | TEK* | Tek | Alliance of Genome Resources | ||||
arteriovenous malformation | ENG* | Eng | Alliance of Genome Resources | ||||
arteriovenous malformation | RASA1* | Rasa1 | Alliance of Genome Resources | ||||
arteriovenous malformations of the brain | IL6* | Il6 | Alliance of Genome Resources | ||||
bile duct adenoma | BRAF* | Braf | Alliance of Genome Resources | ||||
biliary tract benign neoplasm | IL4* | Il4 | Alliance of Genome Resources | ||||
biliary tract benign neoplasm | MUC1* | Muc1 | Alliance of Genome Resources | ||||
biliary tract benign neoplasm | ALB* | Alb | Alliance of Genome Resources | ||||
biliary tract benign neoplasm | MTAP* | Mtap | Alliance of Genome Resources | ||||
choroid plexus papilloma | TP53* | Trp53 | Alliance of Genome Resources | ||||
colorectal adenoma | PTGIS* | Ptgis | Alliance of Genome Resources | ||||
colorectal adenoma | CYP24A1* | Cyp24a1 | Alliance of Genome Resources | ||||
colorectal adenoma | GSTM1*, GSTM5 | Gstm1, Gstm2, Gstm3, Gstm6 | Alliance of Genome Resources | ||||
colorectal adenoma | GSTP1* | Gstp1, Gstp2, Gstp3, Gstp-ps | Alliance of Genome Resources | ||||
colorectal adenoma | MAPK8* | Mapk8 | Alliance of Genome Resources | ||||
dysembryoplastic neuroepithelial tumor | BRAF* | Braf | Alliance of Genome Resources | ||||
endometrial hyperplasia | KRAS* | Kras | Alliance of Genome Resources | ||||
familial hepatic adenoma | HNF1A* | Hnf1a | Alliance of Genome Resources | ||||
fibroma | ANTXR2* | Antxr2 | Alliance of Genome Resources | ||||
glomangioma | GLMN* | Glmn | Alliance of Genome Resources | ||||
growth hormone secreting pituitary adenoma 2 | GPR101* | Gpr101 | Alliance of Genome Resources | ||||
hepatic angiomyolipoma | TSC2* | Tsc2 | Alliance of Genome Resources | ||||
hepatocellular adenoma | HNF1A* | Hnf1a | Alliance of Genome Resources | ||||
infantile myofibromatosis | NOTCH3* | Notch3 | Alliance of Genome Resources | ||||
insulinoma | INS* | Ins1, Ins2 | Alliance of Genome Resources | ||||
kidney angiomyolipoma | MTOR* | Mtor | Alliance of Genome Resources | ||||
lipoma | HMGA2* | Hmga2 | Alliance of Genome Resources | ||||
liver benign neoplasm | TUT4* | Tut4 | Alliance of Genome Resources | ||||
nephroma | DICER1* | Dicer1 | Alliance of Genome Resources | ||||
neurilemmoma | LZTR1* | Lztr1 | Alliance of Genome Resources | ||||
neurilemmoma | NF2* | Nf2 | Alliance of Genome Resources | ||||
neurilemmoma | CDKN2A* | Cdkn2a | Alliance of Genome Resources | ||||
pancreatic mucinous cystadenoma | KRAS* | Kras | Alliance of Genome Resources | ||||
paraganglioma | DLST* | Dlst | Alliance of Genome Resources | ||||
paraganglioma | SDHAF2* | Sdhaf2 | Alliance of Genome Resources | ||||
paraganglioma | SDHA* | Sdha | Alliance of Genome Resources | ||||
paraganglioma | SDHB* | Sdhb | Alliance of Genome Resources | ||||
paraganglioma | SDHC* | Sdhc | 1 "NOT" model | Alliance of Genome Resources | |||
paraganglioma | SDHD* | Sdhd | 3 "NOT" models | Alliance of Genome Resources | |||
paraganglioma | SLC25A11* | Slc25a11 | Alliance of Genome Resources | ||||
paranasal sinus benign neoplasm | TP53* | Trp53 | Alliance of Genome Resources | ||||
pheochromocytoma | SDHB* | Sdhb | 1 model | Alliance of Genome Resources | |||
pheochromocytoma | VHL*, VHLL | Vhl | Alliance of Genome Resources | ||||
pheochromocytoma | TMEM127* | Tmem127 | Alliance of Genome Resources | ||||
pheochromocytoma | MAX* | Max | Alliance of Genome Resources | ||||
pheochromocytoma | HSD17B10* | Hsd17b10 | Alliance of Genome Resources | ||||
pilomatrixoma | CTNNB1* | Ctnnb1 | Alliance of Genome Resources | ||||
pituitary adenoma 1 | AIP* | Aip | Alliance of Genome Resources | ||||
pituitary adenoma 3 | GNAS* | Gnas | Alliance of Genome Resources | ||||
pituitary adenoma 5 | CDH23* | Cdh23 | Alliance of Genome Resources | ||||
pleomorphic adenoma | PLAG1* | Plag1 | Alliance of Genome Resources | ||||
pleomorphic xanthoastrocytoma | BRAF* | Braf | Alliance of Genome Resources | ||||
rectal benign neoplasm | PIK3CA* | Pik3ca | Alliance of Genome Resources | ||||
rectal benign neoplasm | MTHFR* | Mthfr | Alliance of Genome Resources | ||||
rectal benign neoplasm | MAPK8* | Mapk8 | Alliance of Genome Resources | ||||
seborrheic keratosis | PIK3CA* | Pik3ca | Alliance of Genome Resources | ||||
skin benign neoplasm | HRAS* | Hras | Alliance of Genome Resources | ||||
subserous uterine fibroid | TNRC6B* | Tnrc6b | Alliance of Genome Resources | ||||
uterine fibroid | ADA* | Ada | Alliance of Genome Resources | ||||
uterine fibroid | TNRC6B* | Tnrc6b | Alliance of Genome Resources | ||||
uterine fibroid | NUAK1* | Nuak1 | Alliance of Genome Resources | ||||
uterine fibroid | IRS1* | Irs1 | Alliance of Genome Resources | ||||
uterine fibroid | COL6A3* | Col6a3 | Alliance of Genome Resources | ||||
uterine fibroid | COL4A2* | Col4a2 | Alliance of Genome Resources | ||||
uterine fibroid | COL4A1* | Col4a1 | Alliance of Genome Resources | ||||
uterine fibroid | BET1L* | Bet1l | Alliance of Genome Resources | ||||
uterine fibroid | GSTM5*, GSTM1 | Gstm1, Gstm2, Gstm3, Gstm6 | Alliance of Genome Resources | ||||
uterine fibroid | DAPK1* | Dapk1 | Alliance of Genome Resources | ||||
von Hippel-Lindau disease | MMP3* | Mmp3 | Alliance of Genome Resources | ||||
von Hippel-Lindau disease | CCND1* | Ccnd1 | Alliance of Genome Resources |
Transgenes and other genome features developed in mice to model this disease.
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Disease Term | Transgenes and Other Genome Features | Mouse Models | |
ACTH-secreting pituitary adenoma | Tg(PyLT)1Vb | 1 model | |
arteriovenous malformations of the brain | Tg(tetO-Notch4*)1Rwng | 1 model | |
choroid plexus papilloma | Tg(LPV-TAg121)2Tvd | 2 models | |
dermoid cyst of ovary | Tg(Amh-SMAD2*)#Jebu | 1 model | |
epidermal appendage tumor | Tg(Tff3-Tmem207)1Tamo | 1 model | |
insulinoma | Tg(RIP1-Tag)2Dh | 1 model | |
lung benign neoplasm | Tg(tetO/CMV-KRAS*G12C)9.1Msmi | 2 models | |
prolactinoma | Tg(Prl-EGFR)#Sme | 1 model | |
von Hippel-Lindau disease | Tg(Ggt1-Hif1a*)43Log | 1 model |