Excel File Text File *Disease is associated/modeled with this Gene or a homolog. More...
      Disease Term Human Homologs Mouse Homologs Mouse Models Homology Source
     Down syndrome DYRK1A Dyrk1a* 7 models Alliance of Genome Resources
Potocki-Lupski syndrome RAI1 Rai1* 3 models Alliance of Genome Resources
     Down syndrome SNAP25* Snap25   Alliance of Genome Resources
Down syndrome SOD1* Sod1   Alliance of Genome Resources
Down syndrome MMP9* Mmp9   Alliance of Genome Resources
Down syndrome MTHFD1* Mthfd1   Alliance of Genome Resources
Down syndrome MTHFR* Mthfr   Alliance of Genome Resources
syndactyly type 1 IHH* Ihh   Alliance of Genome Resources
syndromic X-linked intellectual disability Lubs type MECP2* Mecp2 1 model Alliance of Genome Resources

 
Transgenes and other genome features developed in mice to model this disease.
     Disease Term Transgenes and Other Genome Features Mouse Models
  chromosomal duplication syndrome Is(In8B2-8B3.1;6C1)1Tshir 1 model
  chromosomal duplication syndrome Lse 1 model
  chromosome 22q13 duplication syndrome Tg(Shank3-EGFP)1Hzo 1 model
  Down syndrome Ts(16C-tel)1Cje 3 models
  Down syndrome Dp(16Hspa13-App)2Yah 1 model
  Down syndrome Dp(16Lipi-Zbtb21)1TybEmcf 1 model
  Down syndrome Dp(17Abcg1-Cbs)1Yah 1 model
  Down syndrome Rb(12.Ts171665Dn)2Cje 1 model
  Down syndrome T(16;17)43H 1 model
  Down syndrome Tg(DYRK1A)36Wjs 1 model
  Down syndrome Tg(Dyrk1a)189N3Yah 1 model
  Down syndrome Tg(MT1A-Dyrk1a)9Xest 1 model
  Down syndrome Tg(MT1A-Dyrk1a)33Xest 1 model
  Down syndrome Tg(MT1A-Dyrk1a)#Xest 1 model
  Down syndrome Tg(RCAN1)M9Mapr 1 model
  Down syndrome Ts(1716)65Dn 5 models
  Potocki-Lupski syndrome Tg(tetO-Rai1,-EGFP)479Walz 1 model
  Potocki-Lupski syndrome Tg(tetO-Rai1,-EGFP)463Walz 1 model
  syndromic X-linked intellectual disability Lubs type Tg(MECP2)1Hzo 2 models
  syndromic X-linked intellectual disability Lubs type Tg(MECP2)3Hzo 1 model