Disease Term | Human Homologs | Mouse Homologs | Mouse Models | Homology Source | |||
Down syndrome | DYRK1A | Dyrk1a* | 7 models | Alliance of Genome Resources | |||
Potocki-Lupski syndrome | RAI1 | Rai1* | 3 models | Alliance of Genome Resources | |||
Down syndrome | SNAP25* | Snap25 | Alliance of Genome Resources | ||||
Down syndrome | SOD1* | Sod1 | Alliance of Genome Resources | ||||
Down syndrome | MMP9* | Mmp9 | Alliance of Genome Resources | ||||
Down syndrome | MTHFD1* | Mthfd1 | Alliance of Genome Resources | ||||
Down syndrome | MTHFR* | Mthfr | Alliance of Genome Resources | ||||
syndactyly type 1 | IHH* | Ihh | Alliance of Genome Resources | ||||
syndromic X-linked intellectual disability Lubs type | MECP2* | Mecp2 | 1 model | Alliance of Genome Resources |
Transgenes and other genome features developed in mice to model this disease.
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Disease Term | Transgenes and Other Genome Features | Mouse Models | |
chromosomal duplication syndrome | Is(In8B2-8B3.1;6C1)1Tshir | 1 model | |
chromosomal duplication syndrome | Lse | 1 model | |
chromosome 22q13 duplication syndrome | Tg(Shank3-EGFP)1Hzo | 1 model | |
Down syndrome | Ts(16C-tel)1Cje | 3 models | |
Down syndrome | Dp(16Hspa13-App)2Yah | 1 model | |
Down syndrome | Dp(16Lipi-Zbtb21)1TybEmcf | 1 model | |
Down syndrome | Dp(17Abcg1-Cbs)1Yah | 1 model | |
Down syndrome | Rb(12.Ts171665Dn)2Cje | 1 model | |
Down syndrome | T(16;17)43H | 1 model | |
Down syndrome | Tg(DYRK1A)36Wjs | 1 model | |
Down syndrome | Tg(Dyrk1a)189N3Yah | 1 model | |
Down syndrome | Tg(MT1A-Dyrk1a)9Xest | 1 model | |
Down syndrome | Tg(MT1A-Dyrk1a)33Xest | 1 model | |
Down syndrome | Tg(MT1A-Dyrk1a)#Xest | 1 model | |
Down syndrome | Tg(RCAN1)M9Mapr | 1 model | |
Down syndrome | Ts(1716)65Dn | 5 models | |
Potocki-Lupski syndrome | Tg(tetO-Rai1,-EGFP)479Walz | 1 model | |
Potocki-Lupski syndrome | Tg(tetO-Rai1,-EGFP)463Walz | 1 model | |
syndromic X-linked intellectual disability Lubs type | Tg(MECP2)1Hzo | 2 models | |
syndromic X-linked intellectual disability Lubs type | Tg(MECP2)3Hzo | 1 model |