Excel File Text File *Disease is associated/modeled with this Gene or a homolog. More...
      Disease Term Human Homologs Mouse Homologs Mouse Models Homology Source
     essential thrombocythemia JAK2* Jak2* 2 models Alliance of Genome Resources
juvenile myelomonocytic leukemia NF1* Nf1* 2 models Alliance of Genome Resources
juvenile myelomonocytic leukemia PTPN11* Ptpn11* 1 model Alliance of Genome Resources
myelofibrosis JAK2* Jak2* 2 models Alliance of Genome Resources
myeloproliferative neoplasm PDGFRB* Pdgfrb* 1 model Alliance of Genome Resources
polycythemia vera JAK2* Jak2* 6 models Alliance of Genome Resources
     essential thrombocythemia MYB Myb* 1 model Alliance of Genome Resources
juvenile myelomonocytic leukemia FLT3 Flt3* 2 models Alliance of Genome Resources
juvenile myelomonocytic leukemia KRAS Kras* 3 models Alliance of Genome Resources
multiple myeloma MAF Maf* 2 models Alliance of Genome Resources
myelodysplastic/myeloproliferative neoplasm DIDO1 Dido1* 1 model Alliance of Genome Resources
myelofibrosis NCOR2 Ncor2* 1 model Alliance of Genome Resources
myelofibrosis MYB Myb* 1 model Alliance of Genome Resources
myelofibrosis GATA1 Gata1* 2 models Alliance of Genome Resources
myeloproliferative neoplasm JAK2 Jak2* 1 model Alliance of Genome Resources
myeloproliferative neoplasm ASXL1 Asxl1* 1 model Alliance of Genome Resources
     atypical chronic myeloid leukemia, BCR-ABL1 negative FGFR1* Fgfr1   Alliance of Genome Resources
essential thrombocythemia SH2B3* Sh2b3   Alliance of Genome Resources
essential thrombocythemia MPL* Mpl   Alliance of Genome Resources
essential thrombocythemia CALR* Calr   Alliance of Genome Resources
essential thrombocythemia THPO* Thpo   Alliance of Genome Resources
essential thrombocythemia VWF* Vwf   Alliance of Genome Resources
juvenile myelomonocytic leukemia CBL* Cbl   Alliance of Genome Resources
juvenile myelomonocytic leukemia JAK3* Jak3   Alliance of Genome Resources
juvenile myelomonocytic leukemia AKAP12* Akap12   Alliance of Genome Resources
juvenile myelomonocytic leukemia ARHGAP26* Arhgap26   Alliance of Genome Resources
juvenile myelomonocytic leukemia CSF2* Csf2   Alliance of Genome Resources
multiple myeloma SOD2* Sod2   Alliance of Genome Resources
multiple myeloma KRAS* Kras   Alliance of Genome Resources
multiple myeloma LIG4* Lig4   Alliance of Genome Resources
multiple myeloma MEFV* Mefv   Alliance of Genome Resources
multiple myeloma MET* Met   Alliance of Genome Resources
multiple myeloma MIR320A* Mir320   Alliance of Genome Resources
multiple myeloma MTHFR* Mthfr   Alliance of Genome Resources
multiple myeloma MTR* Mtr   Alliance of Genome Resources
multiple myeloma MTRR* Mtrr   Alliance of Genome Resources
multiple myeloma NFKBIA* Nfkbia   Alliance of Genome Resources
multiple myeloma NQO1* Nqo1   Alliance of Genome Resources
multiple myeloma NRAS* Nras   Alliance of Genome Resources
multiple myeloma PF4*, PF4V1 Pf4   Alliance of Genome Resources
multiple myeloma POLR1G* Polr1g   Alliance of Genome Resources
multiple myeloma PON1* Pon1   Alliance of Genome Resources
multiple myeloma RBP1* Rbp1   Alliance of Genome Resources
multiple myeloma ROBO1* Robo1   Alliance of Genome Resources
multiple myeloma SPARC* Sparc   Alliance of Genome Resources
multiple myeloma SPP1* Spp1   Alliance of Genome Resources
multiple myeloma TFRC* Tfrc   Alliance of Genome Resources
multiple myeloma TGFB1* Tgfb1   Alliance of Genome Resources
multiple myeloma TNF* Tnf   Alliance of Genome Resources
multiple myeloma TNFRSF10A*, TNFRSF10B, TNFRSF10C, TNFRSF10D Tnfrsf10b   Alliance of Genome Resources
multiple myeloma TNFRSF17* Tnfrsf17   Alliance of Genome Resources
multiple myeloma TP53* Trp53   Alliance of Genome Resources
multiple myeloma TYMS* Tyms   Alliance of Genome Resources
multiple myeloma VEGFA* Vegfa   Alliance of Genome Resources
multiple myeloma XPO5* Xpo5   Alliance of Genome Resources
multiple myeloma XRCC3* Xrcc3   Alliance of Genome Resources
multiple myeloma XRCC4* Xrcc4   Alliance of Genome Resources
multiple myeloma XRCC5* Xrcc5   Alliance of Genome Resources
multiple myeloma ABCG2* Abcg2, Abcg3   Alliance of Genome Resources
multiple myeloma ACE* Ace   Alliance of Genome Resources
multiple myeloma APOE* Apoe   Alliance of Genome Resources
multiple myeloma BCL2L10* Bcl2l10   Alliance of Genome Resources
multiple myeloma CBX7* Cbx7   Alliance of Genome Resources
multiple myeloma CCND1* Ccnd1   Alliance of Genome Resources
multiple myeloma CD40* Cd40   Alliance of Genome Resources
multiple myeloma CD40LG* Cd40lg   Alliance of Genome Resources
multiple myeloma CDKN2A* Cdkn2a   Alliance of Genome Resources
multiple myeloma CFHR1*, CFHR2 Cfhr1   Alliance of Genome Resources
multiple myeloma CTLA4* Ctla4   Alliance of Genome Resources
multiple myeloma CYP1A1* Cyp1a1   Alliance of Genome Resources
multiple myeloma CYP2C19*, CYP2C8, CYP2C9, CYP2C18 Cyp2c29, Cyp2c37, Cyp2c38, Cyp2c39, Cyp2c50, Cyp2c55, Cyp2c65, Cyp2c66   Alliance of Genome Resources
multiple myeloma EPHX1* Ephx1   Alliance of Genome Resources
multiple myeloma ERCC1* Ercc1   Alliance of Genome Resources
multiple myeloma ERCC2* Ercc2   Alliance of Genome Resources
multiple myeloma FCGR2A*, FCGR2B, FCGR2C Fcgr2b, Fcgr3   Alliance of Genome Resources
multiple myeloma FGG* Fgg   Alliance of Genome Resources
multiple myeloma GPX1* Gpx1   Alliance of Genome Resources
multiple myeloma GPX3* Gpx3   Alliance of Genome Resources
multiple myeloma GSTM1*, GSTM5 Gstm1, Gstm2, Gstm3, Gstm6   Alliance of Genome Resources
multiple myeloma GSTP1* Gstp1, Gstp2, Gstp3, Gstp-ps   Alliance of Genome Resources
multiple myeloma GSTT1* Gstt1   Alliance of Genome Resources
multiple myeloma HFE* Hfe   Alliance of Genome Resources
multiple myeloma HK1* Hk1   Alliance of Genome Resources
multiple myeloma ICAM1* Icam1   Alliance of Genome Resources
multiple myeloma IL1A* Il1a   Alliance of Genome Resources
multiple myeloma IL1B* Il1b   Alliance of Genome Resources
multiple myeloma IL1RN* Il1rn   Alliance of Genome Resources
multiple myeloma IL4R* Il4ra   Alliance of Genome Resources
multiple myeloma IL10* Il10   Alliance of Genome Resources
multiple myeloma IRF4* Irf4   Alliance of Genome Resources
multiple myeloma IRF8* Irf8   Alliance of Genome Resources
myelofibrosis EZH2* Ezh2   Alliance of Genome Resources
myelofibrosis ASXL1* Asxl1   Alliance of Genome Resources
myelofibrosis CALR* Calr   Alliance of Genome Resources
myelofibrosis HFE* Hfe   Alliance of Genome Resources
myelofibrosis KMT2A* Kmt2a   Alliance of Genome Resources
myelofibrosis MPL* Mpl   Alliance of Genome Resources
myelofibrosis SH2B3* Sh2b3   Alliance of Genome Resources
myeloid neoplasm MTHFR* Mthfr   Alliance of Genome Resources
myeloid neoplasm JAK2* Jak2   Alliance of Genome Resources
myeloid neoplasm ETV6* Etv6   Alliance of Genome Resources
myeloid neoplasm FGFR1* Fgfr1   Alliance of Genome Resources
myeloid neoplasm GPX1* Gpx1   Alliance of Genome Resources
myeloid neoplasm CBL* Cbl   Alliance of Genome Resources
myeloid neoplasm MECOM* Mecom   Alliance of Genome Resources
myeloproliferative disorder with eosinophilia PDGFRB* Pdgfrb   Alliance of Genome Resources
myeloproliferative neoplasm DDX41* Ddx41   Alliance of Genome Resources
myeloproliferative neoplasm TET2* Tet2   Alliance of Genome Resources
myeloproliferative neoplasm ETV6* Etv6   Alliance of Genome Resources
polycythemia vera HFE* Hfe   Alliance of Genome Resources
polycythemia vera GSTM1*, GSTM5 Gstm1, Gstm2, Gstm3, Gstm6   Alliance of Genome Resources
transient myeloproliferative syndrome GATA1* Gata1 2 models Alliance of Genome Resources

 
Transgenes and other genome features developed in mice to model this disease.
     Disease Term Transgenes and Other Genome Features Mouse Models
  essential thrombocythemia Tg(Vav1-JAK2*V617F)AZjz 1 model
  essential thrombocythemia Tg(JAK2*V617F)FF1Rsko 1 model
  multiple myeloma Tg(Cd4-NPM/ALK)N1Ingh 1 model
  multiple myeloma Tg(Igh-Maf)68Staka 1 model
  multiple myeloma Tg(Igh-Maf)524Staka 1 model
  multiple myeloma Tg(Igkv3-5*-MYC)24Plbe 1 model
  myelofibrosis Tg(H2-Kb-Jak2*V617F)2Shmd 1 model
  myelofibrosis Tg(Vav1-JAK2*V617F)AZjz 1 model
  myeloproliferative neoplasm Tg(Vav1-Asxl1*Y588X)#Fcy 1 model
  polycythemia vera Tg(Vav1-JAK2*V617F)AZjz 1 model
  polycythemia vera Tg(JAK2*V617F)FF1Rsko 1 model