Disease Term | Human Homologs | Mouse Homologs | Mouse Models | Homology Source | |||
COVID-19 | ACE2* | Ace2* | 1 model | Alliance of Genome Resources | |||
Middle East respiratory syndrome | DPP4* | Dpp4* | 5 models | Alliance of Genome Resources | |||
Coronavirus infectious disease | SERPINE1 | Serpine1* | 1 model | Alliance of Genome Resources | |||
Coronavirus infectious disease | TICAM2 | Ticam2* | 1 model | Alliance of Genome Resources | |||
Coronavirus infectious disease | CCR1 | Ccr1*, Ccr1l1 | 1 model | Alliance of Genome Resources | |||
Coronavirus infectious disease | CCR2 | Ccr2* | 1 model | Alliance of Genome Resources | |||
Coronavirus infectious disease | CCR5 | Ccr5* | 1 model | Alliance of Genome Resources | |||
Coronavirus infectious disease | EGFR | Egfr* | 1 model | Alliance of Genome Resources | |||
Coronavirus infectious disease | MUC4 | Muc4* | 1 model | Alliance of Genome Resources | |||
Coronavirus infectious disease | MYD88 | Myd88* | 1 model | Alliance of Genome Resources | |||
Coronavirus infectious disease | PPP1R14C | Ppp1r14c* | 1 model | Alliance of Genome Resources | |||
severe acute respiratory syndrome | STAT1 | Stat1* | 1 model | Alliance of Genome Resources | |||
Coronavirus infectious disease | ACE* | Ace | Alliance of Genome Resources | ||||
Coronavirus infectious disease | CD209*, CLEC4M | Cd209a, Cd209b, Cd209c, Cd209d, Cd209e | Alliance of Genome Resources | ||||
Coronavirus infectious disease | MBL2* | Mbl2 | Alliance of Genome Resources | ||||
COVID-19 | HLA-B*, HLA-C*, HLA-A, HLA-E, HLA-F, HLA-G, HLA-H | H2-D1, H2-K1, H2-L, H2-M1, H2-M2, H2-M3, H2-M5, H2-M9, H2-M10.1, H2-M10.2, H2-M10.3, H2-M10.4, H2-M10.5, H2-M10.6, H2-M11, H2-Q1, H2-Q2, H2-Q4, H2-Q6, H2-Q7, H2-Q8, H2-Q10, H2-T3, H2-T10, H2-T22, H2-T23 | Alliance of Genome Resources | ||||
COVID-19 | IFITM3*, IFITM2 | Ifitm2, Ifitm3, Ifitm7 | Alliance of Genome Resources | ||||
COVID-19 | IFNB1* | Ifnb1 | Alliance of Genome Resources | ||||
COVID-19 | IFNL1*, IFNL2, IFNL3 | Ifnl2, Ifnl3 | Alliance of Genome Resources | ||||
COVID-19 | KIR3DS1*, KIR2DL1, KIR2DL2, KIR2DL3, KIR2DL4, KIR2DL5A, KIR2DL5B, KIR2DP1, KIR2DS1, KIR2DS2, KIR2DS3, KIR2DS4, KIR2DS5, KIR3DL1, KIR3DL2, KIR3DL3, KIR3DP1 | Kir3dl1, Kir3dl2 | Alliance of Genome Resources | ||||
COVID-19 | PLG* | Plg | Alliance of Genome Resources | ||||
COVID-19 | SERPINF2* | Serpinf2 | Alliance of Genome Resources | ||||
COVID-19 | TLR7* | Tlr7 | Alliance of Genome Resources | ||||
COVID-19 | SERPING1* | Serping1 | Alliance of Genome Resources | ||||
COVID-19 | A2M* | A2m | Alliance of Genome Resources | ||||
COVID-19 | ABO* | Abo | Alliance of Genome Resources | ||||
COVID-19 | ACE* | Ace | Alliance of Genome Resources | ||||
COVID-19 | AGTR1* | Agtr1a, Agtr1b | Alliance of Genome Resources | ||||
COVID-19 | C3* | C3 | Alliance of Genome Resources | ||||
COVID-19 | C4BPA* | C4bp, Zp3r | Alliance of Genome Resources | ||||
COVID-19 | C4BPB* | ||||||
COVID-19 | CFH* | Cfh, Cfhr4 | Alliance of Genome Resources | ||||
COVID-19 | F3* | F3 | Alliance of Genome Resources | ||||
COVID-19 | GSTT1* | Gstt1 | Alliance of Genome Resources | ||||
severe acute respiratory syndrome | HLA-B*, HLA-A, HLA-C, HLA-E, HLA-F, HLA-G, HLA-H | H2-D1, H2-K1, H2-L, H2-M1, H2-M2, H2-M3, H2-M5, H2-M9, H2-M10.1, H2-M10.2, H2-M10.3, H2-M10.4, H2-M10.5, H2-M10.6, H2-M11, H2-Q1, H2-Q2, H2-Q4, H2-Q6, H2-Q7, H2-Q8, H2-Q10, H2-T3, H2-T10, H2-T22, H2-T23 | Alliance of Genome Resources | ||||
severe acute respiratory syndrome | CLEC4M*, CD209 | Cd209a, Cd209b, Cd209c, Cd209d, Cd209e | Alliance of Genome Resources | ||||
severe acute respiratory syndrome | ABO* | Abo | Alliance of Genome Resources | ||||
severe acute respiratory syndrome | CCL5* | Ccl5 | Alliance of Genome Resources | ||||
severe acute respiratory syndrome | ACE2* | Ace2 | Alliance of Genome Resources | ||||
severe acute respiratory syndrome | IFNG* | Ifng | Alliance of Genome Resources | ||||
severe acute respiratory syndrome | HLA-DRB1*, HLA-DRB3, HLA-DRB4, HLA-DRB5 | H2-Eb1, H2-Eb2 | Alliance of Genome Resources |
Transgenes and other genome features developed in mice to model this disease.
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Disease Term | Transgenes and Other Genome Features | Mouse Models | |
Coronavirus infectious disease | Tg(FOXJ1-ACE2)1Rba | 1 model | |
COVID-19 | Tg(K18-ACE2)2Prlmn | 1 model | |
COVID-19 | Tg(FOXJ1-ACE2)1Rba | 1 model | |
COVID-19 | Tg(Ace2-ACE2)1Cqin | 1 model | |
Middle East respiratory syndrome | Tg(CAG-DPP4)4Yuzh | 1 model | |
Middle East respiratory syndrome | Tg(CAG-DPP4)52Ctkt | 1 model | |
Middle East respiratory syndrome | Tg(DPP4)2Nnag | 1 model | |
Middle East respiratory syndrome | Tg(KRT18-DPP4)3Pbmj | 1 model | |
Middle East respiratory syndrome | Tg(Tk1-DPP4)27Ysj | 1 model | |
severe acute respiratory syndrome | Tg(Ace2-ACE2)1Cqin | 1 model | |
severe acute respiratory syndrome | Tg(CAG-ACE2)AC70Ctkt | 1 model | |
severe acute respiratory syndrome | Tg(FOXJ1-ACE2)1Rba | 1 model | |
severe acute respiratory syndrome | Tg(K18-ACE2)2Prlmn | 1 model |