| Disease Term | Human Homologs | Mouse Homologs | Mouse Models | Homology Source | |||
  | progeria | LMNA* | Lmna* | 14 models | Alliance of Genome Resources | ||
| Werner syndrome | WRN* | Wrn* | 2 models | Alliance of Genome Resources | |||
| | progeria | SIRT6 | Sirt6* | 1 model | Alliance of Genome Resources | ||
| progeria | VCPIP1 | Vcpip1* | 1 model | Alliance of Genome Resources | |||
| progeria | ZMPSTE24 | Zmpste24* | 3 models | Alliance of Genome Resources | |||
| XFE progeroid syndrome | ERCC1 | Ercc1* | 1 model | Alliance of Genome Resources | |||
| | Nestor-Guillermo progeria syndrome | BANF1* | Banf1 | Alliance of Genome Resources | |||
| progeria | GH1*, CSH1, CSH2, CSHL1, GH2 | Gh | Alliance of Genome Resources | ||||
| Werner syndrome | LMNA* | Lmna | Alliance of Genome Resources | ||||
| Wiedemann-Rautenstrauch syndrome | POLR3A* | Polr3a | Alliance of Genome Resources | ||||
| XFE progeroid syndrome | ERCC4* | Ercc4 | Alliance of Genome Resources | ||||
Excel File
|
Transgenes and other genome features developed in mice to model this disease.
|
|||
| Disease Term | Transgenes and Other Genome Features | Mouse Models | |
| progeria | Tg(LMNA*G608G)HClns | 1 model | |
| progeria | Tg(tetO-LMNA*G608G,-EGFP)VF1-07Maer | 1 model | |
| Werner syndrome | Tg(CAG-WRN*K577M)5025Wcl | 1 model | |