| Disease Term | Human Homologs | Mouse Homologs | Mouse Models | Homology Source | |||
  | Brugada syndrome 1 | SCN5A* | Scn5a* | 2 models | Alliance of Genome Resources | ||
| Brugada syndrome 7 | SCN3B* | Scn3b* | 1 model | Alliance of Genome Resources | |||
| catecholaminergic polymorphic ventricular tachycardia 1 | RYR2* | Ryr2* | 10 models | Alliance of Genome Resources | |||
| catecholaminergic polymorphic ventricular tachycardia 2 | CASQ2* | Casq2* | 4 models | Alliance of Genome Resources | |||
| progressive familial heart block type IA | SCN5A* | Scn5a* | 2 models | Alliance of Genome Resources | |||
| short QT syndrome | KCNH2* | Kcnh2* | 1 model | Alliance of Genome Resources | |||
| sick sinus syndrome | SCN5A* | Scn5a* | 2 models | Alliance of Genome Resources | |||
| | atrial fibrillation | RBM20 | Rbm20* | 1 model | Alliance of Genome Resources | ||
| catecholaminergic polymorphic ventricular tachycardia | FKBP1B | Fkbp1b* | 1 model | Alliance of Genome Resources | |||
| heart conduction disease | SLC6A2 | Slc6a2* | 1 model | Alliance of Genome Resources | |||
| sick sinus syndrome | HCN1 | Hcn1* | 1 model | Alliance of Genome Resources | |||
| sinoatrial node disease | ANK2 | Ank2* | 1 model | Alliance of Genome Resources | |||
| Wolff-Parkinson-White syndrome | MAP3K7 | Map3k7* | 1 model | Alliance of Genome Resources | |||
| Wolff-Parkinson-White syndrome | BMPR1A | Bmpr1a* | 1 model | Alliance of Genome Resources | |||
| | atrial fibrillation | MMP3* | Mmp3 | Alliance of Genome Resources | |||
| atrial fibrillation | ACE* | Ace | Alliance of Genome Resources | ||||
| atrial fibrillation | AGT* | Agt | Alliance of Genome Resources | ||||
| atrial fibrillation | AGXT2* | Agxt2 | Alliance of Genome Resources | ||||
| atrial fibrillation | ANK2* | Ank2 | Alliance of Genome Resources | ||||
| atrial fibrillation | GATA5* | Gata5 | Alliance of Genome Resources | ||||
| atrial fibrillation | GJA5* | Gja5 | Alliance of Genome Resources | ||||
| atrial fibrillation | ISL1* | Isl1 | Alliance of Genome Resources | ||||
| atrial fibrillation | KCNE1* | Kcne1 | Alliance of Genome Resources | ||||
| atrial fibrillation | KCNE2* | Kcne2 | Alliance of Genome Resources | ||||
| atrial fibrillation | KCNJ5* | Kcnj5 | Alliance of Genome Resources | ||||
| atrial fibrillation | KCNQ1* | Kcnq1 | Alliance of Genome Resources | ||||
| atrial fibrillation | MMP1* | Mmp1a, Mmp1b | Alliance of Genome Resources | ||||
| atrial fibrillation | VWF* | Vwf | Alliance of Genome Resources | ||||
| atrial standstill 1 | GJA5* | Gja5 | Alliance of Genome Resources | ||||
| atrial standstill 2 | NPPA* | Nppa | Alliance of Genome Resources | ||||
| atrioventricular block | NKX2-5* | Nkx2-5 | Alliance of Genome Resources | ||||
| atrioventricular block | LMNA* | Lmna | Alliance of Genome Resources | ||||
| Brugada syndrome 2 | GPD1L* | Gpd1l | Alliance of Genome Resources | ||||
| Brugada syndrome 3 | CACNA1C* | Cacna1c | Alliance of Genome Resources | ||||
| Brugada syndrome 4 | CACNB2* | Cacnb2 | Alliance of Genome Resources | ||||
| Brugada syndrome 5 | SCN1B* | Scn1b | Alliance of Genome Resources | ||||
| Brugada syndrome 6 | KCNE3* | Kcne3 | Alliance of Genome Resources | ||||
| Brugada syndrome 8 | HCN4* | Hcn4 | Alliance of Genome Resources | ||||
| Brugada syndrome 9 | KCND3* | Kcnd3 | Alliance of Genome Resources | ||||
| catecholaminergic polymorphic ventricular tachycardia | TRDN* | Trdn | Alliance of Genome Resources | ||||
| catecholaminergic polymorphic ventricular tachycardia 3 | TECRL* | Tecrl | Alliance of Genome Resources | ||||
| catecholaminergic polymorphic ventricular tachycardia 4 | CALM1* | Calm1 | Alliance of Genome Resources | ||||
| catecholaminergic polymorphic ventricular tachycardia 5 | TRDN* | Trdn | Alliance of Genome Resources | ||||
| familial atrial fibrillation | ABCC9* | Abcc9 | Alliance of Genome Resources | ||||
| familial atrial fibrillation | GATA5* | Gata5 | Alliance of Genome Resources | ||||
| familial atrial fibrillation | GJA5* | Gja5 | Alliance of Genome Resources | ||||
| familial atrial fibrillation | KCNA5* | Kcna5 | Alliance of Genome Resources | ||||
| familial atrial fibrillation | KCNE2* | Kcne2 | Alliance of Genome Resources | ||||
| familial atrial fibrillation | KCNJ2* | Kcnj2 | Alliance of Genome Resources | ||||
| familial atrial fibrillation | KCNQ1* | Kcnq1 | Alliance of Genome Resources | ||||
| familial atrial fibrillation | MYL4* | Myl4 | Alliance of Genome Resources | ||||
| familial atrial fibrillation | NKX2-6* | Nkx2-6 | Alliance of Genome Resources | ||||
| familial atrial fibrillation | NPPA* | Nppa | Alliance of Genome Resources | ||||
| familial atrial fibrillation | NUP155* | Nup155 | Alliance of Genome Resources | ||||
| familial atrial fibrillation | SCN1B* | Scn1b | Alliance of Genome Resources | ||||
| familial atrial fibrillation | SCN2B* | Scn2b | Alliance of Genome Resources | ||||
| familial atrial fibrillation | SCN5A* | Scn5a | Alliance of Genome Resources | ||||
| familial atrial fibrillation | ZFHX3* | Zfhx3 | Alliance of Genome Resources | ||||
| progressive familial heart block type IB | TRPM4* | Trpm4 | Alliance of Genome Resources | ||||
| short QT syndrome | KCNJ2* | Kcnj2 | Alliance of Genome Resources | ||||
| short QT syndrome | KCNQ1* | Kcnq1 | Alliance of Genome Resources | ||||
| sick sinus syndrome | AGT* | Agt | Alliance of Genome Resources | ||||
| sick sinus syndrome | MYH6* | Myh6 | Alliance of Genome Resources | ||||
| sick sinus syndrome | HCN4* | Hcn4 | 1 model | Alliance of Genome Resources | |||
| sick sinus syndrome | ANK2* | Ank2 | Alliance of Genome Resources | ||||
| Wolff-Parkinson-White syndrome | MYH6* | Myh6 | Alliance of Genome Resources | ||||
| Wolff-Parkinson-White syndrome | PRKAG2* | Prkag2 | Alliance of Genome Resources | ||||
Excel File
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Transgenes and other genome features developed in mice to model this disease.
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| Disease Term | Transgenes and Other Genome Features | Mouse Models | |
| familial atrial fibrillation | Tg(Myh6*/tetO-SCN5A*F1759A)#Marx | 1 model | |
| Wolff-Parkinson-White syndrome | Tg(Myh6-PRKAG2*R302Q)#Rro | 1 model | |
| Wolff-Parkinson-White syndrome | Tg(CAG-Map3k7*K63W)1232Mds | 1 model | |
| Wolff-Parkinson-White syndrome | Tg(Myh6-PRKAG2*R531G)22Dca | 1 model | |