Excel File Text File *Disease is associated/modeled with this Gene or a homolog. More...
      Disease Term Human Homologs Mouse Homologs Mouse Models Homology Source
     Alzheimer's disease PLAU* Plau* 1 model Alliance of Genome Resources
Alzheimer's disease PSEN1* Psen1* 19 models Alliance of Genome Resources
Alzheimer's disease APP* App* 24 models Alliance of Genome Resources
Alzheimer's disease LRP1* Lrp1* 2 models Alliance of Genome Resources
Alzheimer's disease MME* Mme* 1 model Alliance of Genome Resources
Alzheimer's disease 3 PSEN1* Psen1* 6 models Alliance of Genome Resources
     Alzheimer's disease CAV1 Cav1* 1 model Alliance of Genome Resources
Alzheimer's disease IL33 Il33* 1 model Alliance of Genome Resources
Alzheimer's disease PIN1 Pin1*, Pin1rt1 2 models Alliance of Genome Resources
Alzheimer's disease PLCB1 Plcb1* 1 model Alliance of Genome Resources
     Alzheimer's disease A2M* A2m   Alliance of Genome Resources
Alzheimer's disease ABAT* Abat   Alliance of Genome Resources
Alzheimer's disease ABCA1* Abca1   Alliance of Genome Resources
Alzheimer's disease ACHE* Ache   Alliance of Genome Resources
Alzheimer's disease ADAM17* Adam17   Alliance of Genome Resources
Alzheimer's disease ADRA1A* Adra1a   Alliance of Genome Resources
Alzheimer's disease ADRB3* Adrb3   Alliance of Genome Resources
Alzheimer's disease AGER* Ager   Alliance of Genome Resources
Alzheimer's disease AGTR1* Agtr1a, Agtr1b   Alliance of Genome Resources
Alzheimer's disease ALDH2* Aldh2 1 model Alliance of Genome Resources
Alzheimer's disease APBB1* Apbb1   Alliance of Genome Resources
Alzheimer's disease APBB2* Apbb2   Alliance of Genome Resources
Alzheimer's disease APOA1* Apoa1   Alliance of Genome Resources
Alzheimer's disease APOA4* Apoa4 1 model Alliance of Genome Resources
Alzheimer's disease APOC1* Apoc1   Alliance of Genome Resources
Alzheimer's disease APOE* Apoe 4 models Alliance of Genome Resources
Alzheimer's disease BACE1* Bace1   Alliance of Genome Resources
Alzheimer's disease BACE2* Bace2   Alliance of Genome Resources
Alzheimer's disease BCHE* Bche   Alliance of Genome Resources
Alzheimer's disease BDNF* Bdnf   Alliance of Genome Resources
Alzheimer's disease C2* C2   Alliance of Genome Resources
Alzheimer's disease C3* C3   Alliance of Genome Resources
Alzheimer's disease CASP7* Casp7   Alliance of Genome Resources
Alzheimer's disease CDK5* Cdk5   Alliance of Genome Resources
Alzheimer's disease CDK5R1* Cdk5r1   Alliance of Genome Resources
Alzheimer's disease CHAT* Chat   Alliance of Genome Resources
Alzheimer's disease CLOCK* Clock   Alliance of Genome Resources
Alzheimer's disease CTSD* Ctsd   Alliance of Genome Resources
Alzheimer's disease CYP19A1* Cyp19a1   Alliance of Genome Resources
Alzheimer's disease CYP46A1* Cyp46a1   Alliance of Genome Resources
Alzheimer's disease DLST* Dlst   Alliance of Genome Resources
Alzheimer's disease ECE1* Ece1   Alliance of Genome Resources
Alzheimer's disease EIF2AK2* Eif2ak2   Alliance of Genome Resources
Alzheimer's disease EIF2S1* Eif2s1   Alliance of Genome Resources
Alzheimer's disease ENO1* Eno1, Eno1b   Alliance of Genome Resources
Alzheimer's disease EPO* Epo   Alliance of Genome Resources
Alzheimer's disease ESR1* Esr1   Alliance of Genome Resources
Alzheimer's disease ESR2* Esr2   Alliance of Genome Resources
Alzheimer's disease FAS* Fas   Alliance of Genome Resources
Alzheimer's disease FYN* Fyn   Alliance of Genome Resources
Alzheimer's disease GAPDH* Gapdh, Gapdh-ps15, Gapdhrt, Gapdhrt2   Alliance of Genome Resources
Alzheimer's disease GAPDHS* Gapdhs   Alliance of Genome Resources
Alzheimer's disease GCG* Gcg   Alliance of Genome Resources
Alzheimer's disease GLUL* Glul   Alliance of Genome Resources
Alzheimer's disease GRIN2B* Grin2b   Alliance of Genome Resources
Alzheimer's disease GRN* Grn   Alliance of Genome Resources
Alzheimer's disease GSK3B* Gsk3b   Alliance of Genome Resources
Alzheimer's disease GSS* Gss   Alliance of Genome Resources
Alzheimer's disease GSTM3* Gstm5   Alliance of Genome Resources
Alzheimer's disease GSTO1* Gsto1   Alliance of Genome Resources
Alzheimer's disease GSTO2* Gsto2   Alliance of Genome Resources
Alzheimer's disease GSTP1* Gstp1, Gstp2, Gstp3, Gstp-ps   Alliance of Genome Resources
Alzheimer's disease GSTT1* Gstt1   Alliance of Genome Resources
Alzheimer's disease HLA-DRB1*, HLA-DRB3, HLA-DRB4, HLA-DRB5 H2-Eb1, H2-Eb2   Alliance of Genome Resources
Alzheimer's disease HFE* Hfe   Alliance of Genome Resources
Alzheimer's disease HMGCR* Hmgcr   Alliance of Genome Resources
Alzheimer's disease HSPA1A*, HSPA1B* Hspa1a, Hspa1b   Alliance of Genome Resources
Alzheimer's disease HTR6* Htr6   Alliance of Genome Resources
Alzheimer's disease ICAM1* Icam1   Alliance of Genome Resources
Alzheimer's disease IGF1* Igf1   Alliance of Genome Resources
Alzheimer's disease IGFBP3* Igfbp3   Alliance of Genome Resources
Alzheimer's disease IL1A* Il1a   Alliance of Genome Resources
Alzheimer's disease IL1B* Il1b   Alliance of Genome Resources
Alzheimer's disease IL2* Il2   Alliance of Genome Resources
Alzheimer's disease IL4* Il4   Alliance of Genome Resources
Alzheimer's disease IL6R* Il6ra   Alliance of Genome Resources
Alzheimer's disease IL10* Il10   Alliance of Genome Resources
Alzheimer's disease IREB2* Ireb2   Alliance of Genome Resources
Alzheimer's disease IRS1* Irs1   Alliance of Genome Resources
Alzheimer's disease KCNMA1* Kcnma1   Alliance of Genome Resources
Alzheimer's disease KLC1* Klc1 1 model Alliance of Genome Resources
Alzheimer's disease KLK6* Klk6   Alliance of Genome Resources
Alzheimer's disease LDLR* Ldlr 1 model Alliance of Genome Resources
Alzheimer's disease LIPC* Lipc   Alliance of Genome Resources
Alzheimer's disease LPL* Lpl   Alliance of Genome Resources
Alzheimer's disease LRP8* Lrp8   Alliance of Genome Resources
Alzheimer's disease LRPAP1* Lrpap1   Alliance of Genome Resources
Alzheimer's disease MAOA* Maoa   Alliance of Genome Resources
Alzheimer's disease MAOB* Maob   Alliance of Genome Resources
Alzheimer's disease MAPT* Mapt 2 models Alliance of Genome Resources
Alzheimer's disease MBL2* Mbl2   Alliance of Genome Resources
Alzheimer's disease MCM2* Mcm2   Alliance of Genome Resources
Alzheimer's disease MT3* Mt3   Alliance of Genome Resources
Alzheimer's disease ND2* mt-Nd2   Alliance of Genome Resources
Alzheimer's disease NCF2* Ncf2   Alliance of Genome Resources
Alzheimer's disease NCSTN* Ncstn   Alliance of Genome Resources
Alzheimer's disease NECTIN2* Nectin2   Alliance of Genome Resources
Alzheimer's disease NEFM* Nefm   Alliance of Genome Resources
Alzheimer's disease NFE2L2* Nfe2l2   Alliance of Genome Resources
Alzheimer's disease NGFR* Ngfr   Alliance of Genome Resources
Alzheimer's disease NOS1* Nos1   Alliance of Genome Resources
Alzheimer's disease NOS3* Nos3   Alliance of Genome Resources
Alzheimer's disease NTF3* Ntf3   Alliance of Genome Resources
Alzheimer's disease NTRK1* Ntrk1   Alliance of Genome Resources
Alzheimer's disease NTRK2* Ntrk2   Alliance of Genome Resources
Alzheimer's disease PARP1* Parp1   Alliance of Genome Resources
Alzheimer's disease PCK1* Pck1   Alliance of Genome Resources
Alzheimer's disease PIK3R1* Pik3r1   Alliance of Genome Resources
Alzheimer's disease PNMT* Pnmt   Alliance of Genome Resources
Alzheimer's disease PON1* Pon1   Alliance of Genome Resources
Alzheimer's disease PON2* Pon2   Alliance of Genome Resources
Alzheimer's disease PON3* Pon3   Alliance of Genome Resources
Alzheimer's disease PPARA* Ppara   Alliance of Genome Resources
Alzheimer's disease PPARG* Pparg   Alliance of Genome Resources
Alzheimer's disease PPP2R2B* Ppp2r2b   Alliance of Genome Resources
Alzheimer's disease PPP3R1* Ppp3r1   Alliance of Genome Resources
Alzheimer's disease PSEN2* Psen2 3 models Alliance of Genome Resources
Alzheimer's disease RCAN1* Rcan1   Alliance of Genome Resources
Alzheimer's disease S100B* S100b   Alliance of Genome Resources
Alzheimer's disease SERPINE2* Serpine2   Alliance of Genome Resources
Alzheimer's disease SNCA* Snca   Alliance of Genome Resources
Alzheimer's disease SOD2* Sod2   Alliance of Genome Resources
Alzheimer's disease SORL1* Sorl1 1 model Alliance of Genome Resources
Alzheimer's disease STAT3* Stat3   Alliance of Genome Resources
Alzheimer's disease TAP2* Tap2   Alliance of Genome Resources
Alzheimer's disease TFAM* Tfam   Alliance of Genome Resources
Alzheimer's disease TLR4* Tlr4   Alliance of Genome Resources
Alzheimer's disease TNF* Tnf   Alliance of Genome Resources
Alzheimer's disease TPH1* Tph1   Alliance of Genome Resources
Alzheimer's disease TTR* Ttr   Alliance of Genome Resources
Alzheimer's disease UCHL1* Uchl1   Alliance of Genome Resources
Alzheimer's disease UQCRC1* Uqcrc1   Alliance of Genome Resources
Alzheimer's disease VEGFA* Vegfa   Alliance of Genome Resources
Alzheimer's disease VLDLR* Vldlr   Alliance of Genome Resources
Alzheimer's disease WT1* Wt1   Alliance of Genome Resources
Alzheimer's disease XRN1* Xrn1   Alliance of Genome Resources
Alzheimer's disease 1 APP* App   Alliance of Genome Resources
Alzheimer's disease 1 MPO* Mpo   Alliance of Genome Resources
Alzheimer's disease 1 PLAU* Plau   Alliance of Genome Resources
Alzheimer's disease 18 ADAM10* Adam10   Alliance of Genome Resources
Alzheimer's disease 2 APOE* Apoe   Alliance of Genome Resources
Alzheimer's disease 3 APOE* Apoe   Alliance of Genome Resources
Alzheimer's disease 4 PSEN2* Psen2 1 model Alliance of Genome Resources
Alzheimer's disease 9 ABCA7* Abca7   Alliance of Genome Resources

 
Transgenes and other genome features developed in mice to model this disease.
     Disease Term Transgenes and Other Genome Features Mouse Models
  Alzheimer's disease Tg(ACTB-APP*V717F)1Colm 1 model
  Alzheimer's disease Tg(APP695)3Dbo 8 models
  Alzheimer's disease Tg(APP)8.9Btla 1 model
  Alzheimer's disease Tg(APPSw)40Btla 2 models
  Alzheimer's disease Tg(APPSWE)2576Kha 13 models
  Alzheimer's disease Tg(APPswe,PSEN1dE9)85Dbo 6 models
  Alzheimer's disease Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas 8 models
  Alzheimer's disease Tg(APPSwLon)96Btla 1 model
  Alzheimer's disease Tg(APPV717F)109Ili 9 models
  Alzheimer's disease Tg(Camk2a-App*,-Apbb1)25Spim 1 model
  Alzheimer's disease Tg(CMV-IgkvaD11)BCat 2 models
  Alzheimer's disease Tg(DMD-APP*)7Neve 1 model
  Alzheimer's disease Tg(DMD-APP*)18Neve 1 model
  Alzheimer's disease Tg(Eno2-APP*Ind)#Kakiz 1 model
  Alzheimer's disease Tg(Eno2-PSEN2)2348Ykk 1 model
  Alzheimer's disease Tg(Eno2-PSEN2*)1480Ykk 1 model
  Alzheimer's disease Tg(Mapt-MAPT*)#Hanr 1 model
  Alzheimer's disease Tg(NEFL-APP)#Nalb 1 model
  Alzheimer's disease Tg(PDGFB-APPInd)F17Plhn 1 model
  Alzheimer's disease Tg(PDGFB-APPSwDutLon)46Lpr 2 models
  Alzheimer's disease Tg(PDGFB-APPSwInd)J9Lms 1 model
  Alzheimer's disease Tg(PDGFB-MAPT*V337M)1Atak 1 model
  Alzheimer's disease Tg(Prnp-APP*)1Hmor 1 model
  Alzheimer's disease Tg(Prnp-App/APPswe)E1-2Dbo 1 model
  Alzheimer's disease Tg(Prnp-APPSweArc)#Rmni 1 model
  Alzheimer's disease Tg(PRNP-APPSweInd)8Dwst 3 models
  Alzheimer's disease Tg(PRNP-APPSweInd)19959Dwst 1 model
  Alzheimer's disease Tg(Prnp-ITM2B/APP695*40)1Emcg 1 model
  Alzheimer's disease Tg(Prnp-ITM2B/APP695*42)A12Emcg 1 model
  Alzheimer's disease Tg(Prnp-MAPT)7Vle 1 model
  Alzheimer's disease Tg(Prnp-MAPT)43Vle 1 model
  Alzheimer's disease Tg(Prnp-MAPT*K274Q*K281Q)286Lgn 1 model
  Alzheimer's disease Tg(Prnp-MAPT*P301L)JNPL3Hlmc 2 models
  Alzheimer's disease Tg(Prnp-MAPT*P301S)PS19Vle 3 models
  Alzheimer's disease Tg(PSEN1dE9)S9Dbo 4 models
  Alzheimer's disease Tg(PSEN1H163R)G9Btla 1 model
  Alzheimer's disease Tg(tetO-APPSwInd)18Dbo 1 model
  Alzheimer's disease Tg(tetO-APPSwInd)102Dbo 1 model
  Alzheimer's disease Tg(tetO-APPSwInd)107Dbo 1 model
  Alzheimer's disease Tg(tetO-APPSwInd)Dbo 2 models
  Alzheimer's disease Tg(tetO-CDK5R1/GFP)337Lht 1 model
  Alzheimer's disease Tg(tetO-HMOX1)6Hyms 1 model
  Alzheimer's disease Tg(tetO-MAPT*K280,-luc)#Eman 1 model
  Alzheimer's disease Tg(tetO/Prnp-APP*Swe*Lon)9191Krz 1 model
  Alzheimer's disease Tg(Thy1-APP)3Somm 3 models
  Alzheimer's disease Tg(Thy1-APP*)2Tbay 1 model
  Alzheimer's disease Tg(Thy1-APP*Swe*Ind)fAccu 1 model
  Alzheimer's disease Tg(Thy1-APPSL)28Lpr 4 models
  Alzheimer's disease Tg(Thy1-APPArc)M8Cagr 2 models
  Alzheimer's disease Tg(Thy1-APPLon)2Vln 4 models
  Alzheimer's disease Tg(Thy1-APPSw)10Jiri 3 models
  Alzheimer's disease Tg(Thy1-APPSw,Thy1-PSEN1*L166P)21Jckr 3 models
  Alzheimer's disease Tg(Thy1-APPSwDutIowa)BWevn 3 models
  Alzheimer's disease Tg(Thy1-APPSweArc)BLngn 1 model
  Alzheimer's disease Tg(Thy1-APPSweAut)A7Tiwa 1 model
  Alzheimer's disease Tg(Thy1-APPSweLon)41Ema 1 model
  Alzheimer's disease Tg(Thy1-MAPT)1Vln 2 models
  Alzheimer's disease Tg(Thy1-MAPT)2Vln 2 models
  Alzheimer's disease Tg(Thy1-MAPT)22Schd 2 models
  Alzheimer's disease Tg(Thy1-MAPT*P301L)2Vln 1 model
  Alzheimer's disease Tg(Thy1-PSEN1*M146V,-APP*Swe)10Arte 1 model
  Alzheimer's disease 3 Tg(APPswe,PSEN1dE9)85Dbo 2 models
  Alzheimer's disease 3 Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas 1 model
  Alzheimer's disease 3 Tg(PSEN1dE9)S9Dbo 4 models
  Alzheimer's disease 3 Tg(PSEN1H163R)G9Btla 1 model
  Alzheimer's disease 4 Tg(APP695)3Dbo 3 models