Disease Term | Human Homologs | Mouse Homologs | Mouse Models | Homology Source | |||
low tension glaucoma | OPTN* | Optn* | 1 model | Alliance of Genome Resources | |||
open-angle glaucoma | MYOC* | Myoc* | 1 model | Alliance of Genome Resources | |||
juvenile glaucoma | PAX6 | Pax6* | 1 model | Alliance of Genome Resources | |||
low tension glaucoma | SLC1A1 | Slc1a1* | 1 model | Alliance of Genome Resources | |||
low tension glaucoma | SOD1 | Sod1* | 1 model | Alliance of Genome Resources | |||
low tension glaucoma | SLC1A3 | Slc1a3* | 1 model | Alliance of Genome Resources | |||
primary open angle glaucoma | GUCY1A1 | Gucy1a1* | 1 model | Alliance of Genome Resources | |||
juvenile glaucoma | MYOC* | Myoc | Alliance of Genome Resources | ||||
low tension glaucoma | TP53* | Trp53 | Alliance of Genome Resources | ||||
low tension glaucoma | TNF* | Tnf | Alliance of Genome Resources | ||||
low tension glaucoma | MYOC* | Myoc | Alliance of Genome Resources | ||||
low tension glaucoma | CAV2* | Cav2 | Alliance of Genome Resources | ||||
low tension glaucoma | APOE* | Apoe | Alliance of Genome Resources | ||||
low tension glaucoma | ADRB1* | Adrb1 | Alliance of Genome Resources | ||||
low tension glaucoma | TLR4* | Tlr4 | Alliance of Genome Resources | ||||
open-angle glaucoma | ADRB2* | Adrb2 | Alliance of Genome Resources | ||||
open-angle glaucoma | AFAP1* | Afap1 | Alliance of Genome Resources | ||||
open-angle glaucoma | APOE* | Apoe | Alliance of Genome Resources | ||||
open-angle glaucoma | CDKN2B* | Cdkn2b | Alliance of Genome Resources | ||||
open-angle glaucoma | GMDS* | Gmds | Alliance of Genome Resources | ||||
open-angle glaucoma | MEIS2* | Meis2 | Alliance of Genome Resources | ||||
open-angle glaucoma | MTHFR* | Mthfr | Alliance of Genome Resources | ||||
open-angle glaucoma | OPTN* | Optn | Alliance of Genome Resources | ||||
open-angle glaucoma | PON1* | Pon1 | Alliance of Genome Resources | ||||
open-angle glaucoma | TAP1* | Tap1 | Alliance of Genome Resources | ||||
open-angle glaucoma | TNF* | Tnf | Alliance of Genome Resources | ||||
primary open angle glaucoma | MMP1* | Mmp1a, Mmp1b | Alliance of Genome Resources | ||||
primary open angle glaucoma | MYOC* | Myoc | Alliance of Genome Resources | ||||
primary open angle glaucoma | NOS3* | Nos3 | Alliance of Genome Resources | ||||
primary open angle glaucoma | OGG1* | Ogg1 | Alliance of Genome Resources | ||||
primary open angle glaucoma | OPTN* | Optn | Alliance of Genome Resources | ||||
primary open angle glaucoma | PON1* | Pon1 | Alliance of Genome Resources | ||||
primary open angle glaucoma | SOD2* | Sod2 | Alliance of Genome Resources | ||||
primary open angle glaucoma | THBS1* | Thbs1 | Alliance of Genome Resources | ||||
primary open angle glaucoma | TLR4* | Tlr4 | Alliance of Genome Resources | ||||
primary open angle glaucoma | TNF* | Tnf | Alliance of Genome Resources | ||||
primary open angle glaucoma | TP53* | Trp53 | Alliance of Genome Resources | ||||
primary open angle glaucoma | WDR36* | Wdr36 | Alliance of Genome Resources | ||||
primary open angle glaucoma | GSTT1* | Gstt1 | Alliance of Genome Resources | ||||
primary open angle glaucoma | GSTM1*, GSTM5 | Gstm1, Gstm2, Gstm3, Gstm6 | Alliance of Genome Resources | ||||
primary open angle glaucoma | ESR2* | Esr2 | Alliance of Genome Resources | ||||
primary open angle glaucoma | CYP1B1* | Cyp1b1 | Alliance of Genome Resources | ||||
primary open angle glaucoma | COL6A3* | Col6a3 | Alliance of Genome Resources | ||||
primary open angle glaucoma | CDKN1A* | Cdkn1a | Alliance of Genome Resources | ||||
primary open angle glaucoma | CAV2* | Cav2 | Alliance of Genome Resources | ||||
primary open angle glaucoma | ADIPOQ* | Adipoq | Alliance of Genome Resources | ||||
primary open angle glaucoma | ACVR1* | Acvr1 | Alliance of Genome Resources | ||||
primary open angle glaucoma | CAV1* | Cav1 | Alliance of Genome Resources | ||||
primary open angle glaucoma | APOE* | Apoe | Alliance of Genome Resources | ||||
primary open angle glaucoma | ADRB2* | Adrb2 | Alliance of Genome Resources | ||||
primary open angle glaucoma | LAMB2* | Lamb2 | Alliance of Genome Resources | ||||
primary open angle glaucoma | LOXL1* | Loxl1 | Alliance of Genome Resources |
Transgenes and other genome features developed in mice to model this disease.
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Disease Term | Transgenes and Other Genome Features | Mouse Models | |
low tension glaucoma | Tg(TBK1)#Andm | 2 models | |
open-angle glaucoma | Tg(Myoc*Y423H)#Sit | 1 model | |
open-angle glaucoma | Tg(MYOC*Y437H)#Sit | 1 model | |
primary open angle glaucoma | Tg(CMV-MYOC*Y437H)#Vcs | 1 model | |
primary open angle glaucoma | Tg(OPTN*E50K,-EGFP)1Mde | 1 model |