Disease Term | Human Homologs | Mouse Homologs | Mouse Models | Homology Source | |||
![]() ![]() | focal segmental glomerulosclerosis 1 | ACTN4* | Actn4* | 1 model | Alliance of Genome Resources | ||
focal segmental glomerulosclerosis 2 | TRPC6* | Trpc6* | 3 models | Alliance of Genome Resources | |||
focal segmental glomerulosclerosis 3 | CD2AP* | Cd2ap* | 1 model | Alliance of Genome Resources | |||
IgA glomerulonephritis | SCGB1A1* | Scgb1a1* | 2 models | Alliance of Genome Resources | |||
karyomegalic interstitial nephritis | FAN1* | Fan1* | 3 models | Alliance of Genome Resources | |||
![]() | focal segmental glomerulosclerosis | TNFAIP2 | Tnfaip2* | 1 model | Alliance of Genome Resources | ||
focal segmental glomerulosclerosis | SRGAP1 | Srgap1* | 1 model | Alliance of Genome Resources | |||
focal segmental glomerulosclerosis | MYO9A | Myo9a* | 1 model | Alliance of Genome Resources | |||
focal segmental glomerulosclerosis | MIR193A | Mir193a* | 2 models | Alliance of Genome Resources | |||
focal segmental glomerulosclerosis | CMAS | Cmas* | 1 model | Alliance of Genome Resources | |||
glomerulonephritis | CFI | Cfi* | 1 model | Alliance of Genome Resources | |||
IgA glomerulonephritis | B4GALT1 | B4galt1* | 1 model | Alliance of Genome Resources | |||
IgA glomerulonephritis | TNFSF13B | Tnfsf13b* | 1 model | Alliance of Genome Resources | |||
IgA glomerulonephritis | TNFSF14 | Tnfsf14* | 1 model | Alliance of Genome Resources | |||
IgA glomerulonephritis | WAS | Was* | 1 model | Alliance of Genome Resources | |||
membranoproliferative glomerulonephritis | CFH | Cfh*, Cfhr4 | 1 model | Alliance of Genome Resources | |||
membranoproliferative glomerulonephritis | TSLP | Tslp* | 1 model | Alliance of Genome Resources | |||
![]() | crescentic glomerulonephritis | IL1RN* | Il1rn | Alliance of Genome Resources | |||
focal segmental glomerulosclerosis | TRPC6* | Trpc6 | Alliance of Genome Resources | ||||
focal segmental glomerulosclerosis | ACTN4* | Actn4 | Alliance of Genome Resources | ||||
focal segmental glomerulosclerosis | CD2AP* | Cd2ap | Alliance of Genome Resources | ||||
focal segmental glomerulosclerosis 5 | INF2* | Inf2 | Alliance of Genome Resources | ||||
focal segmental glomerulosclerosis 6 | MYO1E* | Myo1e | Alliance of Genome Resources | ||||
focal segmental glomerulosclerosis 7 | PAX2* | Pax2 | Alliance of Genome Resources | ||||
focal segmental glomerulosclerosis 8 | ANLN* | Anln | Alliance of Genome Resources | ||||
focal segmental glomerulosclerosis 9 | CRB2* | Crb2 | Alliance of Genome Resources | ||||
glomerulonephritis | CNDP1* | Cndp1 | Alliance of Genome Resources | ||||
glomerulonephritis | VEGFA* | Vegfa | Alliance of Genome Resources | ||||
glomerulonephritis | TPO* | Tpo | Alliance of Genome Resources | ||||
glomerulonephritis | SERPINE1* | Serpine1 | Alliance of Genome Resources | ||||
glomerulonephritis | SCGB1A1* | Scgb1a1 | Alliance of Genome Resources | ||||
glomerulonephritis | MTHFR* | Mthfr | Alliance of Genome Resources | ||||
glomerulonephritis | IL1RN* | Il1rn | Alliance of Genome Resources | ||||
glomerulonephritis | C1QA* | C1qa | Alliance of Genome Resources | ||||
glomerulonephritis | F2* | F2 | Alliance of Genome Resources | ||||
glomerulonephritis | FCGR3A*, FCGR3B | Fcgr4 | Alliance of Genome Resources | ||||
glomerulonephritis | FCGR2B*, FCGR2A, FCGR2C | Fcgr2b, Fcgr3 | Alliance of Genome Resources | ||||
glomerulosclerosis | HBEGF* | Hbegf | Alliance of Genome Resources | ||||
glomerulosclerosis | PLA2G7* | Pla2g7 | Alliance of Genome Resources | ||||
IgA glomerulonephritis | SELL* | Sell | Alliance of Genome Resources | ||||
IgA glomerulonephritis | ADD2* | Add2 | Alliance of Genome Resources | ||||
IgA glomerulonephritis | AGTR2* | Agtr2 | Alliance of Genome Resources | ||||
IgA glomerulonephritis | CD14* | Cd14 | Alliance of Genome Resources | ||||
IgA glomerulonephritis | CFB* | Cfb | Alliance of Genome Resources | ||||
IgA glomerulonephritis | CHGA* | Chga | Alliance of Genome Resources | ||||
IgA glomerulonephritis | CXCR2* | Cxcr2 | Alliance of Genome Resources | ||||
IgA glomerulonephritis | FCAR* | ||||||
IgA glomerulonephritis | FCGR3A*, FCGR3B | Fcgr4 | Alliance of Genome Resources | ||||
IgA glomerulonephritis | HLA-DQB1*, HLA-DQB2 | H2-Ab1 | Alliance of Genome Resources | ||||
IgA glomerulonephritis | IGF1R* | Igf1r | Alliance of Genome Resources | ||||
IgA glomerulonephritis | IL1B* | Il1b | Alliance of Genome Resources | ||||
IgA glomerulonephritis | IL1RN* | Il1rn | Alliance of Genome Resources | ||||
IgA glomerulonephritis | MTR* | Mtr | Alliance of Genome Resources | ||||
IgA glomerulonephritis | MUC20* | Muc20 | Alliance of Genome Resources | ||||
IgA glomerulonephritis | NGF* | Ngf | Alliance of Genome Resources | ||||
IgA glomerulonephritis | PDE5A* | Pde5a | Alliance of Genome Resources | ||||
IgA glomerulonephritis | PLA2G7* | Pla2g7 | Alliance of Genome Resources | ||||
IgA glomerulonephritis | SELE* | Sele | Alliance of Genome Resources | ||||
IgA glomerulonephritis | SERPINB7* | Serpinb7 | Alliance of Genome Resources | ||||
IgA glomerulonephritis | SPRY2* | Spry2 | Alliance of Genome Resources | ||||
IgA glomerulonephritis | STAT4* | Stat4 | Alliance of Genome Resources | ||||
IgA glomerulonephritis | TLR1* | Tlr1 | Alliance of Genome Resources | ||||
IgA glomerulonephritis | TLR9* | Tlr9 | Alliance of Genome Resources | ||||
IgA glomerulonephritis | TNFRSF1A* | Tnfrsf1a | Alliance of Genome Resources | ||||
IgA glomerulonephritis | TNFRSF1B* | Tnfrsf1b | Alliance of Genome Resources | ||||
IgA glomerulonephritis | ACE* | Ace | Alliance of Genome Resources | ||||
IgA glomerulonephritis | ACSM3* | Acsm3 | Alliance of Genome Resources | ||||
IgA glomerulonephritis | ADD1* | Add1 | Alliance of Genome Resources | ||||
interstitial nephritis | CRP* | Crp | Alliance of Genome Resources | ||||
lupus nephritis | CFH* | Cfh, Cfhr4 | Alliance of Genome Resources | ||||
lupus nephritis | TLR9* | Tlr9 | Alliance of Genome Resources | ||||
lupus nephritis | SNRPE* | Snrpe, Snrpert | Alliance of Genome Resources | ||||
lupus nephritis | PDCD1* | Pdcd1 | Alliance of Genome Resources | ||||
lupus nephritis | MPO* | Mpo | Alliance of Genome Resources | ||||
lupus nephritis | MBL2* | Mbl2 | Alliance of Genome Resources | ||||
lupus nephritis | KLKB1* | Klkb1 | Alliance of Genome Resources | ||||
lupus nephritis | ITGAM* | Itgam | Alliance of Genome Resources | ||||
lupus nephritis | IFNG* | Ifng | Alliance of Genome Resources | ||||
lupus nephritis | HLA-DRB1*, HLA-DRB3, HLA-DRB4, HLA-DRB5 | H2-Eb1, H2-Eb2 | Alliance of Genome Resources | ||||
lupus nephritis | FCGR2A*, FCGR2B, FCGR2C | Fcgr2b, Fcgr3 | Alliance of Genome Resources | ||||
lupus nephritis | CTLA4* | Ctla4 | Alliance of Genome Resources | ||||
lupus nephritis | CRP* | Crp | Alliance of Genome Resources | ||||
lupus nephritis | AGER* | Ager | Alliance of Genome Resources | ||||
lupus nephritis | HLA-DQA1*, HLA-DQA2 | H2-Aa | Alliance of Genome Resources | ||||
lupus nephritis | CD40LG* | Cd40lg | Alliance of Genome Resources | ||||
lupus nephritis | CCL2*, CCL13 | Ccl2, Ccl12 | Alliance of Genome Resources | ||||
lupus nephritis | TNFRSF1B* | Tnfrsf1b | Alliance of Genome Resources | ||||
membranoproliferative glomerulonephritis | FN1* | Fn1 | Alliance of Genome Resources | ||||
membranoproliferative glomerulonephritis | CFB* | Cfb | Alliance of Genome Resources | ||||
membranous glomerulonephritis | CFB* | Cfb | Alliance of Genome Resources | ||||
membranous glomerulonephritis | MME* | Mme | Alliance of Genome Resources | ||||
membranous glomerulonephritis | HLA-DQA1*, HLA-DQA2 | H2-Aa | Alliance of Genome Resources | ||||
nephritis | NOS3* | Nos3 | Alliance of Genome Resources | ||||
nephritis | PARP1* | Parp1 | Alliance of Genome Resources | ||||
nephritis | SNRPD1* | Snrpd1 | Alliance of Genome Resources | ||||
nephritis | FOXC2* | Foxc2 | Alliance of Genome Resources | ||||
nephritis | ACE* | Ace | Alliance of Genome Resources |
Transgenes and other genome features developed in mice to model this disease.
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Disease Term | Transgenes and Other Genome Features | Mouse Models | |
focal segmental glomerulosclerosis | Tg(Thy1/THY1)T6Gsv | 1 model | |
focal segmental glomerulosclerosis 2 | Tg(NPHS2-Trpc6*E896K)F75aWalz | 1 model | |
focal segmental glomerulosclerosis 2 | Tg(NPHS2-Trpc6)F419Walz | 1 model | |
focal segmental glomerulosclerosis 2 | Tg(NPHS2-Trpc6*P111Q)F615Walz | 1 model | |
IgA glomerulonephritis | Tg(Itgam-FCAR)83Rcmo | 1 model | |
IgA glomerulonephritis | Tg(Lck-Tnfsf14)24Yxf | 1 model | |
IgA glomerulonephritis | Tg(MMTV-Scgb1a1)#Abm | 1 model | |
IgA glomerulonephritis | Tg(Tnfsf13b)1Fma | 1 model | |
membranoproliferative glomerulonephritis | Tg(Lck-Tslp)1Chea | 1 model |