| Disease Term | Human Homologs | Mouse Homologs | Mouse Models | Homology Source | |||
  | alpha-2-plasmin inhibitor deficiency | SERPINF2* | Serpinf2* | 1 model | Alliance of Genome Resources | ||
| antithrombin III deficiency | SERPINC1* | Serpinc1* | 1 model | Alliance of Genome Resources | |||
| Bernard-Soulier syndrome | GP1BB* | Gp1bb* | 4 models | Alliance of Genome Resources | |||
| Bernard-Soulier syndrome | GP1BA* | Gp1ba* | 1 model | Alliance of Genome Resources | |||
| congenital afibrinogenemia | FGG* | Fgg* | 1 model | Alliance of Genome Resources | |||
| factor VIII deficiency | F8* | F8* | 2 models | Alliance of Genome Resources | |||
| factor XI deficiency | F11* | F11* | 1 model | Alliance of Genome Resources | |||
| factor XII deficiency | F12* | F12* | 1 model | Alliance of Genome Resources | |||
| factor XIII deficiency | F13A1* | F13a1* | 2 models | Alliance of Genome Resources | |||
| Glanzmann's thrombasthenia | ITGB3* | Itgb3* | 1 model | Alliance of Genome Resources | |||
| gray platelet syndrome | NBEAL2* | Nbeal2* | 3 models | Alliance of Genome Resources | |||
| hemophilia B | F9* | F9* | 5 models | Alliance of Genome Resources | |||
| MYH-9 related disease | MYH9* | Myh9* | 4 models | Alliance of Genome Resources | |||
| platelet-type bleeding disorder 10 | CD36* | Cd36* | 1 model | Alliance of Genome Resources | |||
| platelet-type bleeding disorder 16 | ITGA2B* | Itga2b* | 1 model | Alliance of Genome Resources | |||
| platelet-type bleeding disorder 16 | ITGB3* | Itgb3* | 1 model | Alliance of Genome Resources | |||
| platelet-type bleeding disorder 8 | P2RY12* | P2ry12* | 2 models | Alliance of Genome Resources | |||
| Stormorken syndrome | STIM1* | Stim1* | 1 model | Alliance of Genome Resources | |||
| thrombocytopenia | GATA1* | Gata1* | 1 model | Alliance of Genome Resources | |||
| von Willebrand's disease | VWF* | Vwf* | 2 models | Alliance of Genome Resources | |||
| von Willebrand's disease 2 | VWF* | Vwf* | 2 models | Alliance of Genome Resources | |||
| | congenital amegakaryocytic thrombocytopenia | MPL | Mpl* | 1 model | Alliance of Genome Resources | ||
| platelet storage pool deficiency | RAB27B | Rab27b* | 2 models | Alliance of Genome Resources | |||
| platelet storage pool deficiency | AP3B1 | Ap3b1* | 3 models | Alliance of Genome Resources | |||
| platelet storage pool deficiency | AP3D1 | Ap3d1* | 1 model | Alliance of Genome Resources | |||
| platelet storage pool deficiency | BLOC1S5 | Bloc1s5* | 2 models | Alliance of Genome Resources | |||
| platelet storage pool deficiency | BLOC1S6 | Bloc1s6* | 1 model | Alliance of Genome Resources | |||
| platelet storage pool deficiency | DOCK7 | Dock7* | 1 model | Alliance of Genome Resources | |||
| platelet storage pool deficiency | DTNBP1 | Dtnbp1* | 1 model | Alliance of Genome Resources | |||
| platelet storage pool deficiency | HPS1 | Hps1* | 2 models | Alliance of Genome Resources | |||
| platelet storage pool deficiency | HPS3 | Hps3* | 2 models | Alliance of Genome Resources | |||
| platelet storage pool deficiency | HPS4 | Hps4* | 1 model | Alliance of Genome Resources | |||
| platelet storage pool deficiency | HPS5 | Hps5* | 2 models | Alliance of Genome Resources | |||
| platelet storage pool deficiency | LYST | Lyst* | 1 model | Alliance of Genome Resources | |||
| platelet storage pool deficiency | RAB27A | Rab27a* | 2 models | Alliance of Genome Resources | |||
| platelet storage pool deficiency | SLC7A11 | Slc7a11* | 1 model | Alliance of Genome Resources | |||
| thrombophilia | THBD | Thbd* | 1 model | Alliance of Genome Resources | |||
| | autosomal dominant macrothrombocytopenia TUBB1-related | TUBB1* | Tubb1 | Alliance of Genome Resources | |||
| autosomal dominant thrombophilia due to protein C deficiency | PROC* | Proc | Alliance of Genome Resources | ||||
| autosomal dominant thrombophilia due to protein S deficiency | PROS1* | Pros1 | Alliance of Genome Resources | ||||
| autosomal hemophilia A | IFNL4* | ||||||
| autosomal recessive thrombophilia due to protein C deficiency | PROC* | Proc | Alliance of Genome Resources | ||||
| autosomal recessive thrombophilia due to protein S deficiency | PROS1* | Pros1 | Alliance of Genome Resources | ||||
| Bernard-Soulier syndrome | VWF* | Vwf | Alliance of Genome Resources | ||||
| Bernard-Soulier syndrome | GP9* | Gp9 | Alliance of Genome Resources | ||||
| Bernard-Soulier syndrome type A2 | GP1BA* | Gp1ba | Alliance of Genome Resources | ||||
| blood platelet disease | CD36* | Cd36 | Alliance of Genome Resources | ||||
| blood platelet disease | ITGB3* | Itgb3 | Alliance of Genome Resources | ||||
| blood platelet disease | TBXA2R* | Tbxa2r | Alliance of Genome Resources | ||||
| blood platelet disease | TPM4* | Tpm4 | Alliance of Genome Resources | ||||
| blood platelet disease | GP6* | Gp6 | Alliance of Genome Resources | ||||
| blood platelet disease | FLI1* | Fli1 | Alliance of Genome Resources | ||||
| blood platelet disease | EPHB2* | Ephb2 | Alliance of Genome Resources | ||||
| combined deficiency of vitamin K-dependent clotting factors 1 | GGCX* | Ggcx | Alliance of Genome Resources | ||||
| combined deficiency of vitamin K-dependent clotting factors 2 | VKORC1* | Vkorc1 | Alliance of Genome Resources | ||||
| congenital afibrinogenemia | FGA* | Fga | Alliance of Genome Resources | ||||
| congenital afibrinogenemia | FGB* | Fgb | Alliance of Genome Resources | ||||
| disseminated intravascular coagulation | F13A1* | F13a1 | Alliance of Genome Resources | ||||
| disseminated intravascular coagulation | F3* | F3 | Alliance of Genome Resources | ||||
| disseminated intravascular coagulation | SERPINC1* | Serpinc1 | Alliance of Genome Resources | ||||
| disseminated intravascular coagulation | TFPI* | Tfpi | Alliance of Genome Resources | ||||
| disseminated intravascular coagulation | THBD* | Thbd | Alliance of Genome Resources | ||||
| factor V deficiency | LMAN1* | Lman1 | Alliance of Genome Resources | ||||
| factor V deficiency | F5* | F5 | Alliance of Genome Resources | ||||
| factor VII deficiency | F7* | F7 | Alliance of Genome Resources | ||||
| factor VIII deficiency | TGFB1* | Tgfb1 | Alliance of Genome Resources | ||||
| factor VIII deficiency | HLA-DQA1*, HLA-DQA2 | H2-Aa | Alliance of Genome Resources | ||||
| factor VIII deficiency | F2* | F2 | Alliance of Genome Resources | ||||
| factor VIII deficiency | HMOX1* | Hmox1 | Alliance of Genome Resources | ||||
| factor VIII deficiency | TFPI* | Tfpi | Alliance of Genome Resources | ||||
| factor VIII deficiency | IL10* | Il10 | Alliance of Genome Resources | ||||
| factor VIII deficiency | PLAT* | Plat | Alliance of Genome Resources | ||||
| factor VIII deficiency | FCGR2A*, FCGR2B, FCGR2C | Fcgr2b, Fcgr3 | Alliance of Genome Resources | ||||
| factor VIII deficiency | IFNG* | Ifng | Alliance of Genome Resources | ||||
| factor VIII deficiency | MTHFR* | Mthfr | Alliance of Genome Resources | ||||
| factor X deficiency | F10* | F10 | Alliance of Genome Resources | ||||
| factor XIII deficiency | LMAN1* | Lman1 | Alliance of Genome Resources | ||||
| Glanzmann's thrombasthenia | ITGA2* | Itga2 | Alliance of Genome Resources | ||||
| Glanzmann's thrombasthenia | ITGA2B* | Itga2b | Alliance of Genome Resources | ||||
| gray platelet syndrome | GFI1B* | Gfi1b | Alliance of Genome Resources | ||||
| hemophilia B | F2* | F2 | Alliance of Genome Resources | ||||
| heparin cofactor II deficiency | SERPIND1* | Serpind1 | Alliance of Genome Resources | ||||
| high molecular weight kininogen deficiency | KNG1* | Kng1, Kng2 | Alliance of Genome Resources | ||||
| platelet-type bleeding disorder 11 | GP6* | Gp6 | Alliance of Genome Resources | ||||
| platelet-type bleeding disorder 15 | ACTN1* | Actn1 | Alliance of Genome Resources | ||||
| platelet-type bleeding disorder 17 | GFI1B* | Gfi1b | Alliance of Genome Resources | ||||
| platelet-type bleeding disorder 18 | RASGRP2* | Rasgrp2 | Alliance of Genome Resources | ||||
| platelet-type bleeding disorder 19 | PRKACG* | ||||||
| platelet-type bleeding disorder 20 | SLFN14* | Slfn14 | Alliance of Genome Resources | ||||
| platelet-type bleeding disorder 3 | GP1BA* | Gp1ba | Alliance of Genome Resources | ||||
| protein C deficiency | PROC* | Proc | Alliance of Genome Resources | ||||
| protein S deficiency | TFPI* | Tfpi | Alliance of Genome Resources | ||||
| protein S deficiency | PROS1* | Pros1 | Alliance of Genome Resources | ||||
| prothrombin deficiency | F2* | F2 | Alliance of Genome Resources | ||||
| purpura | IL13* | Il13 | Alliance of Genome Resources | ||||
| Quebec platelet disorder | PLAU* | Plau | Alliance of Genome Resources | ||||
| Scott syndrome | ANO6* | Ano6 | Alliance of Genome Resources | ||||
| thrombocytopenia | ITGA2B* | Itga2b | Alliance of Genome Resources | ||||
| thrombocytopenia | TUBA8* | Tuba8 | Alliance of Genome Resources | ||||
| thrombocytopenia | TNF* | Tnf | Alliance of Genome Resources | ||||
| thrombocytopenia | THPO* | Thpo | Alliance of Genome Resources | ||||
| thrombocytopenia | SRC* | Src | Alliance of Genome Resources | ||||
| thrombocytopenia | RAP1B*, RAP1BL | Rap1b | Alliance of Genome Resources | ||||
| thrombocytopenia | PTPRJ* | Ptprj | Alliance of Genome Resources | ||||
| thrombocytopenia | MYH9* | Myh9 | Alliance of Genome Resources | ||||
| thrombocytopenia | MTHFR* | Mthfr | Alliance of Genome Resources | ||||
| thrombocytopenia | MPL* | Mpl | Alliance of Genome Resources | ||||
| thrombocytopenia | MBL2* | Mbl2 | Alliance of Genome Resources | ||||
| thrombocytopenia | MASTL* | Mastl | Alliance of Genome Resources | ||||
| thrombocytopenia | ITPA* | Itpa | Alliance of Genome Resources | ||||
| thrombocytopenia | ITGB3* | Itgb3 | Alliance of Genome Resources | ||||
| thrombocytopenia | WAS* | Was | Alliance of Genome Resources | ||||
| thrombocytopenia | ITGA2* | Itga2 | Alliance of Genome Resources | ||||
| thrombocytopenia | IL10* | Il10 | Alliance of Genome Resources | ||||
| thrombocytopenia | IL1B* | Il1b | Alliance of Genome Resources | ||||
| thrombocytopenia | IKZF5* | Ikzf5 | Alliance of Genome Resources | ||||
| thrombocytopenia | IFNL3*, IFNL1, IFNL2 | Ifnl2, Ifnl3 | Alliance of Genome Resources | ||||
| thrombocytopenia | FYB1* | Fyb1 | Alliance of Genome Resources | ||||
| thrombocytopenia | FLI1* | Fli1 | Alliance of Genome Resources | ||||
| thrombocytopenia | FCGR2A*, FCGR2B, FCGR2C | Fcgr2b, Fcgr3 | Alliance of Genome Resources | ||||
| thrombocytopenia | F7* | F7 | Alliance of Genome Resources | ||||
| thrombocytopenia | ETV6* | Etv6 | Alliance of Genome Resources | ||||
| thrombocytopenia | CYCS* | Cycs | Alliance of Genome Resources | ||||
| thrombocytopenia | CCL2*, CCL13 | Ccl2, Ccl12 | Alliance of Genome Resources | ||||
| thrombocytopenia | BRIP1* | Brip1 | Alliance of Genome Resources | ||||
| thrombocytopenia | ANKRD26* | Ankrd26 | Alliance of Genome Resources | ||||
| thrombocytopenia | ACTB* | Actb | Alliance of Genome Resources | ||||
| thrombocytopenia due to platelet alloimmunization | FCGR3A*, FCGR3B | Fcgr4 | Alliance of Genome Resources | ||||
| thrombocytosis | CALR* | Calr | Alliance of Genome Resources | ||||
| thrombocytosis | THPO* | Thpo | Alliance of Genome Resources | ||||
| thrombocytosis | MPL* | Mpl | Alliance of Genome Resources | ||||
| thrombocytosis | IL1B* | Il1b | Alliance of Genome Resources | ||||
| thrombocytosis | JAK2* | Jak2 | Alliance of Genome Resources | ||||
| thrombophilia | MTHFR* | Mthfr | Alliance of Genome Resources | ||||
| thrombophilia | PLG* | Plg | Alliance of Genome Resources | ||||
| thrombophilia | PROC* | Proc | Alliance of Genome Resources | ||||
| thrombophilia | SERPINA10* | Serpina10 | Alliance of Genome Resources | ||||
| thrombophilia | FGA* | Fga | Alliance of Genome Resources | ||||
| thrombophilia | HLA-DQA1*, HLA-DQA2 | H2-Aa | Alliance of Genome Resources | ||||
| thrombophilia due to activated protein C resistance | F5* | F5 | Alliance of Genome Resources | ||||
| thrombophilia due to activated protein C resistance | PROC* | Proc | Alliance of Genome Resources | ||||
| thrombophilia due to HRG deficiency | HRG* | Hrg | Alliance of Genome Resources | ||||
| thrombophilia due to thrombin defect | HABP2* | Habp2 | Alliance of Genome Resources | ||||
| thrombophilia due to thrombin defect | MTHFR* | Mthfr | Alliance of Genome Resources | ||||
| thrombophilia due to thrombin defect | F13A1* | F13a1 | Alliance of Genome Resources | ||||
| thrombophilia due to thrombin defect | F2* | F2 | Alliance of Genome Resources | ||||
| thrombophilia due to thrombomodulin defect | THBD* | Thbd | Alliance of Genome Resources | ||||
| thrombotic thrombocytopenic purpura | HLA-DQB1*, HLA-DQB2 | H2-Ab1 | Alliance of Genome Resources | ||||
| thrombotic thrombocytopenic purpura | ADAMTS13* | Adamts13 | Alliance of Genome Resources | ||||
| von Willebrand's disease | F3* | F3 | Alliance of Genome Resources | ||||
| von Willebrand's disease 1 | ITGA2B* | Itga2b | Alliance of Genome Resources | ||||
| von Willebrand's disease 1 | ITGA2* | Itga2 | Alliance of Genome Resources | ||||
| von Willebrand's disease 1 | VWF* | Vwf | Alliance of Genome Resources | ||||
| von Willebrand's disease 1 | PLAT* | Plat | Alliance of Genome Resources | ||||
| von Willebrand's disease 2 | ITGA2* | Itga2 | Alliance of Genome Resources | ||||
| von Willebrand's disease 3 | VWF* | Vwf | Alliance of Genome Resources | ||||
| X-linked thrombophilia due to factor IX defect | F9* | F9 | Alliance of Genome Resources | ||||
Excel File
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Transgenes and other genome features developed in mice to model this disease.
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| Disease Term | Transgenes and Other Genome Features | Mouse Models | |
| blood coagulation disease | Tg(JAK2*V617F)FF1Rsko | 1 model | |
| thrombocytopenia | Tg(Gata1*V205G)1Mym | 1 model | |