Disease Term | Human Homologs | Mouse Homologs | Mouse Models | Homology Source | |||
atypical teratoid rhabdoid tumor | SMARCB1* | Smarcb1* | 3 models | Alliance of Genome Resources | |||
medulloblastoma | PTCH1 | Ptch1* | 12 models | Alliance of Genome Resources | |||
medulloblastoma | IFNG | Ifng* | 2 models | Alliance of Genome Resources | |||
medulloblastoma | SMO | Smo* | 8 models | Alliance of Genome Resources | |||
brain cancer | TERT* | Tert | Alliance of Genome Resources | ||||
brain cancer | CCDC26* | ||||||
brain cancer | CDKN2B-AS1* | ||||||
brain glioma | ADAM3A* | Adam3 | Alliance of Genome Resources | ||||
brain glioma | XRCC3* | Xrcc3 | Alliance of Genome Resources | ||||
brain glioma | XRCC1* | Xrcc1 | Alliance of Genome Resources | ||||
brain glioma | PTPRB* | Ptprb | Alliance of Genome Resources | ||||
chordoid glioma | PRKCA* | Prkca | Alliance of Genome Resources | ||||
medulloblastoma | SUFU* | Sufu | 1 model | Alliance of Genome Resources | |||
medulloblastoma | TSC2* | Tsc2 | Alliance of Genome Resources | ||||
medulloblastoma | BRCA2* | Brca2 | 2 models | Alliance of Genome Resources | |||
medulloblastoma | CTNNB1* | Ctnnb1 | Alliance of Genome Resources | ||||
medulloblastoma | ELP1* | Elp1 | Alliance of Genome Resources | ||||
medulloblastoma | GPR161* | Gpr161 | Alliance of Genome Resources | ||||
medulloblastoma | GSTM1*, GSTM5 | Gstm1, Gstm2, Gstm3, Gstm6 | Alliance of Genome Resources | ||||
medulloblastoma | GSTT1* | Gstt1 | Alliance of Genome Resources | ||||
medulloblastoma | PTCH2* | Ptch2 | 2 models | Alliance of Genome Resources | |||
medulloblastoma | APC* | Apc | Alliance of Genome Resources | ||||
optic nerve glioma | NF1* | Nf1 | Alliance of Genome Resources |
Transgenes and other genome features developed in mice to model this disease.
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Disease Term | Transgenes and Other Genome Features | Mouse Models | |
medulloblastoma | Tg(Neurod2-Smo*A1)199Jols | 3 models | |
medulloblastoma | Tg(Neurod2-Smo*A2)#Jols | 1 model | |
medulloblastoma | Tg(tetO-Ifng)184Pop | 2 models | |
medulloblastoma | Tg(tetO-MYCN,-luc)#Waw | 2 models | |
medulloblastoma | Tg(tetO-TAg,CMV-rtTA)123Yihu | 1 model |