| Disease Term | Human Homologs | Mouse Homologs | Mouse Models | Homology Source | |||
  | melanoma | BRAF* | Braf* | 1 model | Alliance of Genome Resources | ||
| | skin melanoma | GRM1 | Grm1* | 2 models | Alliance of Genome Resources | ||
| uveal melanoma | GRM1 | Grm1* | 1 model | Alliance of Genome Resources | |||
| | familial melanoma | XRCC3* | Xrcc3 | Alliance of Genome Resources | |||
| familial melanoma | TERT* | Tert | Alliance of Genome Resources | ||||
| familial melanoma | STK11* | Stk11 | Alliance of Genome Resources | ||||
| familial melanoma | POT1* | Pot1a, Pot1b | Alliance of Genome Resources | ||||
| familial melanoma | BRAF* | Braf | Alliance of Genome Resources | ||||
| familial melanoma | CDK4* | Cdk4 | Alliance of Genome Resources | ||||
| familial melanoma | CDKN2A* | Cdkn2a | Alliance of Genome Resources | ||||
| familial melanoma | MC1R* | Mc1r | Alliance of Genome Resources | ||||
| familial melanoma | MITF* | Mitf | Alliance of Genome Resources | ||||
| melanoma | ERCC2* | Ercc2 | Alliance of Genome Resources | ||||
| melanoma | ERCC5* | Ercc5 | Alliance of Genome Resources | ||||
| melanoma | FAS* | Fas | Alliance of Genome Resources | ||||
| melanoma | FASLG* | Fasl | Alliance of Genome Resources | ||||
| melanoma | GSTP1* | Gstp1, Gstp2, Gstp3, Gstp-ps | Alliance of Genome Resources | ||||
| melanoma | HLA-DQA1*, HLA-DQA2 | H2-Aa | Alliance of Genome Resources | ||||
| melanoma | IL1RN* | Il1rn | Alliance of Genome Resources | ||||
| melanoma | JUNB* | Junb | Alliance of Genome Resources | ||||
| melanoma | KDM7A* | Kdm7a | Alliance of Genome Resources | ||||
| melanoma | MAPK1* | Mapk1 | Alliance of Genome Resources | ||||
| melanoma | MC1R* | Mc1r | Alliance of Genome Resources | ||||
| melanoma | NAF1* | Naf1 | Alliance of Genome Resources | ||||
| melanoma | NFKB1* | Nfkb1 | Alliance of Genome Resources | ||||
| melanoma | NFKBIA* | Nfkbia | Alliance of Genome Resources | ||||
| melanoma | NRAS* | Nras | Alliance of Genome Resources | ||||
| melanoma | RNASET2* | Rnaset2a, Rnaset2b | Alliance of Genome Resources | ||||
| melanoma | RTEL1* | Rtel1 | Alliance of Genome Resources | ||||
| melanoma | SPP1* | Spp1 | Alliance of Genome Resources | ||||
| melanoma | STN1* | Stn1 | Alliance of Genome Resources | ||||
| melanoma | TERC* | ||||||
| melanoma | TERT* | Tert | Alliance of Genome Resources | ||||
| melanoma | TLR4* | Tlr4 | Alliance of Genome Resources | ||||
| melanoma | TP53* | Trp53 | Alliance of Genome Resources | ||||
| melanoma | TYR* | Tyr | Alliance of Genome Resources | ||||
| melanoma | VDR* | Vdr | Alliance of Genome Resources | ||||
| melanoma | LRP1B* | Lrp1b | Alliance of Genome Resources | ||||
| melanoma | AGER* | Ager | Alliance of Genome Resources | ||||
| melanoma | ASS1* | Ass1 | Alliance of Genome Resources | ||||
| melanoma | BMP4* | Bmp4 | Alliance of Genome Resources | ||||
| melanoma | BRCA2* | Brca2 | Alliance of Genome Resources | ||||
| melanoma | CAT* | Cat | Alliance of Genome Resources | ||||
| melanoma | CD40* | Cd40 | Alliance of Genome Resources | ||||
| melanoma | CDKN2A* | Cdkn2a | 5 models | Alliance of Genome Resources | |||
| melanoma | CTLA4* | Ctla4 | Alliance of Genome Resources | ||||
| skin melanoma | CCL2*, CCL13 | Ccl2, Ccl12 | Alliance of Genome Resources | ||||
| skin melanoma | CDKN2A* | Cdkn2a | 5 models | Alliance of Genome Resources | |||
| skin melanoma | CTCF* | Ctcf | Alliance of Genome Resources | ||||
| skin melanoma | DDR1* | Ddr1 | Alliance of Genome Resources | ||||
| skin melanoma | FANCA* | Fanca | Alliance of Genome Resources | ||||
| skin melanoma | GSTM1*, GSTM5 | Gstm1, Gstm2, Gstm3, Gstm6 | Alliance of Genome Resources | ||||
| skin melanoma | GSTT1* | Gstt1 | Alliance of Genome Resources | ||||
| skin melanoma | ICAM1* | Icam1 | Alliance of Genome Resources | ||||
| skin melanoma | MMP1* | Mmp1a, Mmp1b | Alliance of Genome Resources | ||||
| skin melanoma | MMP9* | Mmp9 | Alliance of Genome Resources | ||||
| skin melanoma | OCA2* | Oca2 | Alliance of Genome Resources | ||||
| skin melanoma | TYR* | Tyr | Alliance of Genome Resources | ||||
| skin melanoma | VDR* | Vdr | Alliance of Genome Resources | ||||
| skin melanoma | ARHGAP44* | Arhgap44 | Alliance of Genome Resources | ||||
| skin melanoma | BRCA2* | Brca2 | Alliance of Genome Resources | ||||
| uveal melanoma | SERPINE1* | Serpine1 | Alliance of Genome Resources | ||||
| uveal melanoma | BRCA2* | Brca2 | Alliance of Genome Resources | ||||
| uveal melanoma | BAP1* | Bap1 | Alliance of Genome Resources | ||||
| uveal melanoma | MBD4* | Mbd4 | Alliance of Genome Resources | ||||
Excel File
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Transgenes and other genome features developed in mice to model this disease.
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| Disease Term | Transgenes and Other Genome Features | Mouse Models | |
| melanoma | Tg(Mt1-RET)304Ina | 3 models | |
| skin melanoma | Tg(CAG-Ptafr)1Tksh | 1 model | |
| skin melanoma | Tg(Dct-Grm1)ESzc | 1 model | |
| skin melanoma | Tg(Mt1-RET)304Ina | 1 model | |
| uveal melanoma | Tg(Dct-Grm1)ESzc | 1 model | |