Disease Term | Human Homologs | Mouse Homologs | Mouse Models | Homology Source | |||
![]() ![]() | osteosarcoma | TP53* | Trp53* | 10 models | Alliance of Genome Resources | ||
![]() | liposarcoma | IL22 | Il22*, Il22b | 1 model | Alliance of Genome Resources | ||
![]() | chondrosarcoma | EXT1* | Ext1 | Alliance of Genome Resources | |||
chondrosarcoma | TAF15* | Taf15 | Alliance of Genome Resources | ||||
chondrosarcoma | COL2A1* | Col2a1 | Alliance of Genome Resources | ||||
dermatofibrosarcoma protuberans | PDGFB* | Pdgfb | Alliance of Genome Resources | ||||
dermatofibrosarcoma protuberans | COL1A1* | Col1a1 | Alliance of Genome Resources | ||||
Ewing sarcoma | EWSR1* | Ewsr1 | Alliance of Genome Resources | ||||
extraskeletal myxoid chondrosarcoma | TAF15* | Taf15 | Alliance of Genome Resources | ||||
extraskeletal myxoid chondrosarcoma | NR4A3* | Nr4a3 | Alliance of Genome Resources | ||||
fibrosarcoma | TNFRSF1A* | Tnfrsf1a | Alliance of Genome Resources | ||||
fibrosarcoma | CDC42* | Cdc42 | Alliance of Genome Resources | ||||
glomus tumor | GLMN* | Glmn | Alliance of Genome Resources | ||||
Kaposi's sarcoma | IL6* | Il6 | Alliance of Genome Resources | ||||
liposarcoma | FUS* | Fus | Alliance of Genome Resources | ||||
localized osteosarcoma | CCNG1* | Ccng1 | Alliance of Genome Resources | ||||
malignant pleural mesothelioma | SMO* | Smo | Alliance of Genome Resources | ||||
malignant pleural mesothelioma | CHRNA7*, CHRFAM7A | Chrna7 | Alliance of Genome Resources | ||||
malignant pleural mesothelioma | NF2* | Nf2 | Alliance of Genome Resources | ||||
malignant pleural mesothelioma | SETD2* | Setd2 | Alliance of Genome Resources | ||||
myxoid liposarcoma | DDIT3* | Ddit3 | Alliance of Genome Resources | ||||
osteosarcoma | GSTM3* | Gstm5 | Alliance of Genome Resources | ||||
osteosarcoma | EZH2* | Ezh2 | Alliance of Genome Resources | ||||
osteosarcoma | ERCC1* | Ercc1 | Alliance of Genome Resources | ||||
osteosarcoma | EFEMP2* | Efemp2 | Alliance of Genome Resources | ||||
osteosarcoma | E2F1* | E2f1 | Alliance of Genome Resources | ||||
osteosarcoma | SERPINF1* | Serpinf1 | Alliance of Genome Resources | ||||
osteosarcoma | RB1* | Rb1 | 6 models | Alliance of Genome Resources | |||
osteosarcoma | PTH* | Pth | Alliance of Genome Resources | ||||
osteosarcoma | MTHFR* | Mthfr | Alliance of Genome Resources | ||||
osteosarcoma | MIR624* | ||||||
osteosarcoma | MIR494* | Mir494 | Alliance of Genome Resources | ||||
osteosarcoma | CXCR4* | Cxcr4 | Alliance of Genome Resources | ||||
osteosarcoma | CHEK2* | Chek2 | Alliance of Genome Resources | ||||
osteosarcoma | CDC5L* | Cdc5l, Cdc5lrt1, Cdc5lrt4, Cdc5lrt5, Cdc5lrt6, Cdc5lrt7, Cdc5lrt8, Cdc5lrt9, Cdc5lrt10 | Alliance of Genome Resources | ||||
osteosarcoma | DDR1* | Ddr1 | Alliance of Genome Resources | ||||
synovial sarcoma | SSX2*, SSX1, SSX2B, SSX3, SSX4, SSX4B, SSX5, SSX6P, SSX7, SSX8P, SSX9P | Ssxa1, Ssxb1, Ssxb2, Ssxb3, Ssxb5, Ssxb6, Ssxb8, Ssxb9, Ssxb10, Ssxb13, Ssxb14, Ssxb15, Ssxb16 | Alliance of Genome Resources | ||||
synovial sarcoma | SS18* | Ss18 | Alliance of Genome Resources |
Transgenes and other genome features developed in mice to model this disease.
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Disease Term | Transgenes and Other Genome Features | Mouse Models | |
Kaposi's sarcoma | Tg(Acta2-RAC1*G12V)33Pjgc | 2 models | |
liposarcoma | Tg(Fabp4-Il22)#Ychn | 1 model | |
osteosarcoma | Tg(Bglap2-TAg)1Rkho | 2 models | |
osteosarcoma | Tg(tetO-RNAi:Trp53)ASlowe | 2 models |