| Disease Term | Human Homologs | Mouse Homologs | Mouse Models | Homology Source | |||
  | essential thrombocythemia | JAK2* | Jak2* | 2 models | Alliance of Genome Resources | ||
| myeloproliferative neoplasm | PDGFRB* | Pdgfrb* | 1 model | Alliance of Genome Resources | |||
| polycythemia vera | JAK2* | Jak2* | 6 models | Alliance of Genome Resources | |||
| | essential thrombocythemia | MYB | Myb* | 1 model | Alliance of Genome Resources | ||
| myeloproliferative neoplasm | ASXL1 | Asxl1* | 1 model | Alliance of Genome Resources | |||
| myeloproliferative neoplasm | JAK2 | Jak2* | 1 model | Alliance of Genome Resources | |||
| | essential thrombocythemia | THPO* | Thpo | Alliance of Genome Resources | |||
| essential thrombocythemia | CALR* | Calr | Alliance of Genome Resources | ||||
| essential thrombocythemia | VWF* | Vwf | Alliance of Genome Resources | ||||
| essential thrombocythemia | MPL* | Mpl | Alliance of Genome Resources | ||||
| essential thrombocythemia | SH2B3* | Sh2b3 | Alliance of Genome Resources | ||||
| myeloproliferative disorder with eosinophilia | PDGFRB* | Pdgfrb | Alliance of Genome Resources | ||||
| myeloproliferative neoplasm | DDX41* | Ddx41 | Alliance of Genome Resources | ||||
| myeloproliferative neoplasm | ETV6* | Etv6 | Alliance of Genome Resources | ||||
| myeloproliferative neoplasm | TET2* | Tet2 | Alliance of Genome Resources | ||||
| polycythemia vera | HFE* | Hfe | Alliance of Genome Resources | ||||
| polycythemia vera | GSTM1*, GSTM5 | Gstm1, Gstm2, Gstm3, Gstm6 | Alliance of Genome Resources | ||||
| transient myeloproliferative syndrome | GATA1* | Gata1 | 2 models | Alliance of Genome Resources | |||
Excel File
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Transgenes and other genome features developed in mice to model this disease.
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| Disease Term | Transgenes and Other Genome Features | Mouse Models | |
| essential thrombocythemia | Tg(Vav1-JAK2*V617F)AZjz | 1 model | |
| essential thrombocythemia | Tg(JAK2*V617F)FF1Rsko | 1 model | |
| myeloproliferative neoplasm | Tg(Vav1-Asxl1*Y588X)#Fcy | 1 model | |
| polycythemia vera | Tg(JAK2*V617F)FF1Rsko | 1 model | |
| polycythemia vera | Tg(Vav1-JAK2*V617F)AZjz | 1 model | |