Excel File Text File *Disease is associated/modeled with this Gene or a homolog. More...
      Disease Term Human Homologs Mouse Homologs Mouse Models Homology Source
     17-beta hydroxysteroid dehydrogenase 3 deficiency HSD17B3* Hsd17b3* 1 model Alliance of Genome Resources
46,XY sex reversal DHH* Dhh* 1 model Alliance of Genome Resources
androgen insensitivity syndrome AR* Ar* 8 models Alliance of Genome Resources
cryptorchidism INSL3* Insl3* 5 models Alliance of Genome Resources
hypogonadotropic hypogonadism 11 with or without anosmia TACR3* Tacr3* 1 model Alliance of Genome Resources
hypogonadotropic hypogonadism 12 with or without anosmia GNRH1* Gnrh1* 1 model Alliance of Genome Resources
hypogonadotropic hypogonadism 13 with or without anosmia KISS1* Kiss1* 2 models Alliance of Genome Resources
hypogonadotropic hypogonadism 7 with or without anosmia GNRHR* Gnrhr* 1 model Alliance of Genome Resources
hypogonadotropic hypogonadism 8 with or without anosmia KISS1R* Kiss1r* 4 models Alliance of Genome Resources
Kallmann syndrome SOX10* Sox10* 1 model Alliance of Genome Resources
ovarian cancer CTNNB1* Ctnnb1* 6 models Alliance of Genome Resources
persistent Mullerian duct syndrome AMHR2* Amhr2* 1 model Alliance of Genome Resources
primary ovarian insufficiency 12 SYCE1* Syce1* 1 model Alliance of Genome Resources
primary ovarian insufficiency 13 MSH5* Msh5* 1 model Alliance of Genome Resources
primary ovarian insufficiency 19 HSF2BP* Hsf2bp* 1 model Alliance of Genome Resources
     46 XX gonadal dysgenesis FANCL Fancl* 1 model Alliance of Genome Resources
androgen insensitivity syndrome FKBP4 Fkbp4* 2 models Alliance of Genome Resources
dermoid cyst of ovary FOXO3, FOXO3B Foxo3* 1 model Alliance of Genome Resources
hyperandrogenism Prl3c1* 1 model
hypogonadotropic hypogonadism NR5A1 Nr5a1* 1 model Alliance of Genome Resources
Kallmann syndrome WDR11 Wdr11* 1 model Alliance of Genome Resources
ovarian cancer APC Apc* 2 models Alliance of Genome Resources
ovarian disease PATL2 Patl2* 1 model Alliance of Genome Resources
ovarian hyperstimulation syndrome NR1H3 Nr1h3* 1 model Alliance of Genome Resources
polycystic ovary syndrome AKT2 Akt2* 1 model Alliance of Genome Resources
primary ovarian insufficiency FANCF Fancf* 1 model Alliance of Genome Resources
primary ovarian insufficiency POLR3H Polr3h* 1 model Alliance of Genome Resources
     46 XX gonadal dysgenesis ZSWIM7* Zswim7   Alliance of Genome Resources
46 XX gonadal dysgenesis FSHR* Fshr   Alliance of Genome Resources
46 XX gonadal dysgenesis SPIDR* Spidr   Alliance of Genome Resources
46,XX sex reversal 1 SRY* Sry   Alliance of Genome Resources
46,XX sex reversal 4 NR5A1* Nr5a1   Alliance of Genome Resources
46,XX sex reversal 5 NR2F2* Nr2f2   Alliance of Genome Resources
46,XY sex reversal SRY* Sry   Alliance of Genome Resources
46,XY sex reversal DHX37* Dhx37   Alliance of Genome Resources
46,XY sex reversal 1 SRY* Sry   Alliance of Genome Resources
46,XY sex reversal 2 NR0B1* Nr0b1   Alliance of Genome Resources
46,XY sex reversal 3 NR5A1* Nr5a1   Alliance of Genome Resources
46,XY sex reversal 5 CBX2* Cbx2   Alliance of Genome Resources
46,XY sex reversal 6 MAP3K1* Map3k1   Alliance of Genome Resources
46,XY sex reversal 7 DHH* Dhh   Alliance of Genome Resources
46,XY sex reversal 8 AKR1C2*, AKR1C4*, AKR1C1, AKR1C3 Akr1c6, Akr1c12, Akr1c13, Akr1c14, Akr1c18, Akr1c19, Akr1c20, Akr1c21, Akr1cl   Alliance of Genome Resources
46,XY sex reversal 9 ZFPM2* Zfpm2   Alliance of Genome Resources
cryptorchidism HOXD13* Hoxd13   Alliance of Genome Resources
cryptorchidism AR* Ar 1 model Alliance of Genome Resources
cryptorchidism RXFP2* Rxfp2 2 models Alliance of Genome Resources
disorder of sexual development HSD17B3* Hsd17b3   Alliance of Genome Resources
disorder of sexual development AMH* Amh   Alliance of Genome Resources
dysgerminoma FGFR2* Fgfr2   Alliance of Genome Resources
dysgerminoma KIT* Kit   Alliance of Genome Resources
gonadal disease LHCGR* Lhcgr   Alliance of Genome Resources
gonadal dysgenesis TSPYL1*, TSPYL6 Tspyl1   Alliance of Genome Resources
hyperandrogenism IL6ST* Il6st   Alliance of Genome Resources
hypogonadism KISS1R* Kiss1r   Alliance of Genome Resources
hypogonadism PROP1* Prop1   Alliance of Genome Resources
hypogonadotropic hypogonadism NHLH2* Nhlh2   Alliance of Genome Resources
hypogonadotropic hypogonadism TCF12* Tcf12   Alliance of Genome Resources
hypogonadotropic hypogonadism NDNF* Ndnf   Alliance of Genome Resources
hypogonadotropic hypogonadism 10 with or without anosmia TAC3* Tac2   Alliance of Genome Resources
hypogonadotropic hypogonadism 14 with or without anosmia WDR11* Wdr11   Alliance of Genome Resources
hypogonadotropic hypogonadism 15 with or without anosmia HS6ST1* Hs6st1   Alliance of Genome Resources
hypogonadotropic hypogonadism 16 with or without anosmia SEMA3A* Sema3a   Alliance of Genome Resources
hypogonadotropic hypogonadism 17 with or without anosmia SPRY4* Spry4   Alliance of Genome Resources
hypogonadotropic hypogonadism 18 with or without anosmia IL17RD* Il17rd   Alliance of Genome Resources
hypogonadotropic hypogonadism 19 with or without anosmia DUSP6* Dusp6   Alliance of Genome Resources
hypogonadotropic hypogonadism 1 with or without anosmia ANOS1*  
hypogonadotropic hypogonadism 20 with or without anosmia FGF17* Fgf17   Alliance of Genome Resources
hypogonadotropic hypogonadism 21 with or without anosmia FLRT3* Flrt3   Alliance of Genome Resources
hypogonadotropic hypogonadism 22 with or without anosmia FEZF1* Fezf1   Alliance of Genome Resources
hypogonadotropic hypogonadism 23 with or without anosmia LHB*, CGB1, CGB2, CGB3, CGB5, CGB7, CGB8 Lhb   Alliance of Genome Resources
hypogonadotropic hypogonadism 24 without anosmia FSHB* Fshb   Alliance of Genome Resources
hypogonadotropic hypogonadism 2 with or without anosmia FGFR1* Fgfr1   Alliance of Genome Resources
hypogonadotropic hypogonadism 3 with or without anosmia PROKR2* Prokr2   Alliance of Genome Resources
hypogonadotropic hypogonadism 4 with or without anosmia PROK2* Prok2   Alliance of Genome Resources
hypogonadotropic hypogonadism 5 with or without anosmia CHD7* Chd7   Alliance of Genome Resources
hypogonadotropic hypogonadism 6 with or without anosmia FGF8* Fgf8   Alliance of Genome Resources
hypogonadotropic hypogonadism 7 with or without anosmia NSMF* Nsmf   Alliance of Genome Resources
hypogonadotropic hypogonadism 7 with or without anosmia FGFR1* Fgfr1   Alliance of Genome Resources
hypogonadotropic hypogonadism 9 with or without anosmia NSMF* Nsmf   Alliance of Genome Resources
Leydig cell hypoplasia LHCGR* Lhcgr   Alliance of Genome Resources
methemoglobinemia and ambiguous genitalia CYB5A* Cyb5a   Alliance of Genome Resources
Mullerian aplasia and hyperandrogenism WNT4* Wnt4   Alliance of Genome Resources
ovarian cancer HFE* Hfe   Alliance of Genome Resources
ovarian cancer HMGA2* Hmga2   Alliance of Genome Resources
ovarian cancer ITGA8* Itga8   Alliance of Genome Resources
ovarian cancer JAK1* Jak1   Alliance of Genome Resources
ovarian cancer JUP* Jup   Alliance of Genome Resources
ovarian cancer LEF1* Lef1   Alliance of Genome Resources
ovarian cancer MBL2* Mbl2   Alliance of Genome Resources
ovarian cancer MIR1271*  
ovarian cancer MMP1* Mmp1a, Mmp1b   Alliance of Genome Resources
ovarian cancer MSLN* Msln   Alliance of Genome Resources
ovarian cancer MUC16* Muc16   Alliance of Genome Resources
ovarian cancer MYO6* Myo6   Alliance of Genome Resources
ovarian cancer NBN* Nbn   Alliance of Genome Resources
ovarian cancer NOD2* Nod2   Alliance of Genome Resources
ovarian cancer NOS3* Nos3   Alliance of Genome Resources
ovarian cancer OGG1* Ogg1   Alliance of Genome Resources
ovarian cancer OIP5-AS1*  
ovarian cancer OPCML* Opcml   Alliance of Genome Resources
ovarian cancer PIK3CA* Pik3ca 1 model Alliance of Genome Resources
ovarian cancer PMS2*, PMS2P1, PMS2P2, PMS2P6 Pms2   Alliance of Genome Resources
ovarian cancer POT1* Pot1a, Pot1b   Alliance of Genome Resources
ovarian cancer PRKCA* Prkca   Alliance of Genome Resources
ovarian cancer PRKN* Prkn   Alliance of Genome Resources
ovarian cancer PTEN* Pten 8 models Alliance of Genome Resources
ovarian cancer RAD51* Rad51   Alliance of Genome Resources
ovarian cancer RASSF1* Rassf1   Alliance of Genome Resources
ovarian cancer RUNX3* Runx3   Alliance of Genome Resources
ovarian cancer SMAD2* Smad2   Alliance of Genome Resources
ovarian cancer SMAD4* Smad4   Alliance of Genome Resources
ovarian cancer SOD2* Sod2   Alliance of Genome Resources
ovarian cancer STAT3* Stat3   Alliance of Genome Resources
ovarian cancer TFRC* Tfrc   Alliance of Genome Resources
ovarian cancer UGT1A1* Ugt1a1   Alliance of Genome Resources
ovarian cancer WRAP53* Wrap53   Alliance of Genome Resources
ovarian cancer BARD1* Bard1   Alliance of Genome Resources
ovarian cancer AURKA* Aurka   Alliance of Genome Resources
ovarian cancer APOB* Apob   Alliance of Genome Resources
ovarian cancer APEX1* Apex1   Alliance of Genome Resources
ovarian cancer AKT1* Akt1   Alliance of Genome Resources
ovarian cancer BRCA2* Brca2 1 model Alliance of Genome Resources
ovarian cancer CAMK2N1* Camk2n1   Alliance of Genome Resources
ovarian cancer CCNG1* Ccng1   Alliance of Genome Resources
ovarian cancer CD59* Cd59a, Cd59b   Alliance of Genome Resources
ovarian cancer CDH1* Cdh1   Alliance of Genome Resources
ovarian cancer CDH13* Cdh13   Alliance of Genome Resources
ovarian cancer CLDN4* Cldn4, Cldn13   Alliance of Genome Resources
ovarian cancer COMT* Comt   Alliance of Genome Resources
ovarian cancer CYP19A1* Cyp19a1   Alliance of Genome Resources
ovarian cancer EEF1A2* Eef1a2   Alliance of Genome Resources
ovarian cancer ERBB2* Erbb2   Alliance of Genome Resources
ovarian cancer FANCA* Fanca   Alliance of Genome Resources
ovarian cancer GHRH* Ghrh   Alliance of Genome Resources
ovarian cancer GSTA1*, GSTA2, GSTA3, GSTA5 Gsta1, Gsta2, Gsta3, Gsta5, Gsta13   Alliance of Genome Resources
ovarian cancer GSTP1* Gstp1, Gstp2, Gstp3, Gstp-ps   Alliance of Genome Resources
ovarian cancer BRCA1* Brca1 2 models Alliance of Genome Resources
ovarian carcinoma CASP6* Casp6   Alliance of Genome Resources
ovarian carcinoma STK11* Stk11   Alliance of Genome Resources
ovarian carcinoma CABIN1* Cabin1   Alliance of Genome Resources
ovarian carcinoma SOCS2* Socs2   Alliance of Genome Resources
ovarian carcinoma AMH* Amh   Alliance of Genome Resources
ovarian carcinoma MMP13* Mmp13   Alliance of Genome Resources
ovarian carcinoma MIR23B* Mir23b   Alliance of Genome Resources
ovarian carcinoma MAP2K6* Map2k6   Alliance of Genome Resources
ovarian carcinoma SOCS1* Socs1   Alliance of Genome Resources
ovarian carcinoma AKT2* Akt2   Alliance of Genome Resources
ovarian carcinoma L1CAM* L1cam   Alliance of Genome Resources
ovarian carcinoma CYTB* mt-Cytb   Alliance of Genome Resources
ovarian carcinoma CCNG1* Ccng1   Alliance of Genome Resources
ovarian carcinoma CCND1* Ccnd1   Alliance of Genome Resources
ovarian carcinoma CAMK2N1* Camk2n1   Alliance of Genome Resources
ovarian clear cell carcinoma ARID1A* Arid1a   Alliance of Genome Resources
ovarian dysgenesis 1 FSHR* Fshr   Alliance of Genome Resources
ovarian dysgenesis 2 BMP15* Bmp15   Alliance of Genome Resources
ovarian dysgenesis 3 PSMC3IP* Psmc3ip   Alliance of Genome Resources
ovarian dysgenesis 4 MCM9* Mcm9   Alliance of Genome Resources
ovarian dysgenesis 5 SOHLH1* Sohlh1   Alliance of Genome Resources
ovarian dysgenesis 6 NUP107* Nup107   Alliance of Genome Resources
ovarian dysgenesis 7 MRPS22* Mrps22   Alliance of Genome Resources
ovarian dysgenesis 8 ESR2* Esr2   Alliance of Genome Resources
ovarian endometrial cancer ARHGEF10L* Arhgef10l   Alliance of Genome Resources
ovarian hyperstimulation syndrome SERPINF1* Serpinf1   Alliance of Genome Resources
ovarian hyperstimulation syndrome FSHR* Fshr   Alliance of Genome Resources
ovarian serous carcinoma MAP2K4* Map2k4   Alliance of Genome Resources
ovarian serous carcinoma ARHGEF10L* Arhgef10l   Alliance of Genome Resources
ovary epithelial cancer NME1* Nme1   Alliance of Genome Resources
ovary epithelial cancer AKAP6* Akap6   Alliance of Genome Resources
ovary epithelial cancer CCR3* Ccr3   Alliance of Genome Resources
ovary epithelial cancer DAXX* Daxx   Alliance of Genome Resources
ovary epithelial cancer ERCC1* Ercc1   Alliance of Genome Resources
ovary epithelial cancer ERCC2* Ercc2   Alliance of Genome Resources
ovary epithelial cancer GSTT1* Gstt1   Alliance of Genome Resources
ovary epithelial cancer H19*  
ovary epithelial cancer KIF1B* Kif1b   Alliance of Genome Resources
ovary epithelial cancer TAB2* Tab2   Alliance of Genome Resources
ovary epithelial cancer GSTM1*, GSTM5 Gstm1, Gstm2, Gstm3, Gstm6   Alliance of Genome Resources
ovary serous adenocarcinoma TP53* Trp53   Alliance of Genome Resources
partial androgen insensitivity syndrome AR* Ar   Alliance of Genome Resources
persistent Mullerian duct syndrome AMH* Amh   Alliance of Genome Resources
polycystic ovary syndrome CYP1A1* Cyp1a1   Alliance of Genome Resources
polycystic ovary syndrome VDR* Vdr   Alliance of Genome Resources
polycystic ovary syndrome FST* Fst   Alliance of Genome Resources
polycystic ovary syndrome CYP19A1* Cyp19a1   Alliance of Genome Resources
polycystic ovary syndrome CAPN10* Capn10   Alliance of Genome Resources
premature menopause POLG* Polg   Alliance of Genome Resources
primary ovarian insufficiency FANCA* Fanca   Alliance of Genome Resources
primary ovarian insufficiency BMP15* Bmp15   Alliance of Genome Resources
primary ovarian insufficiency DIAPH2* Diaph2   Alliance of Genome Resources
primary ovarian insufficiency TP63* Trp63   Alliance of Genome Resources
primary ovarian insufficiency MSH4* Msh4   Alliance of Genome Resources
primary ovarian insufficiency POLG* Polg   Alliance of Genome Resources
primary ovarian insufficiency XPO5* Xpo5   Alliance of Genome Resources
primary ovarian insufficiency MEIOB* Meiob   Alliance of Genome Resources
primary ovarian insufficiency KASH5* Kash5   Alliance of Genome Resources
primary ovarian insufficiency BBS9* Bbs9   Alliance of Genome Resources
primary ovarian insufficiency 1 FMR1* Fmr1   Alliance of Genome Resources
primary ovarian insufficiency 10 MCM8* Mcm8   Alliance of Genome Resources
primary ovarian insufficiency 11 ERCC6* Ercc6   Alliance of Genome Resources
primary ovarian insufficiency 14 GDF9* Gdf9   Alliance of Genome Resources
primary ovarian insufficiency 15 FANCM* Fancm   Alliance of Genome Resources
primary ovarian insufficiency 16 BNC1* Bnc1   Alliance of Genome Resources
primary ovarian insufficiency 17 XRCC2* Xrcc2   Alliance of Genome Resources
primary ovarian insufficiency 18 C14orf39* 4930447C04Rik   Alliance of Genome Resources
primary ovarian insufficiency 2A DIAPH2* Diaph2   Alliance of Genome Resources
primary ovarian insufficiency 2B POF1B* Pof1b   Alliance of Genome Resources
primary ovarian insufficiency 3 FOXL2* Foxl2   Alliance of Genome Resources
primary ovarian insufficiency 5 NOBOX* Nobox   Alliance of Genome Resources
primary ovarian insufficiency 6 FIGLA* Figla   Alliance of Genome Resources
primary ovarian insufficiency 7 NR5A1* Nr5a1   Alliance of Genome Resources
primary ovarian insufficiency 8 STAG3* Stag3   Alliance of Genome Resources
primary ovarian insufficiency 9 HFM1* Hfm1   Alliance of Genome Resources
testicular cancer GSTP1* Gstp1, Gstp2, Gstp3, Gstp-ps   Alliance of Genome Resources
testicular lymphoma MYD88* Myd88   Alliance of Genome Resources
Turner syndrome VDR* Vdr   Alliance of Genome Resources
Turner syndrome IGFBP3* Igfbp3   Alliance of Genome Resources

 
Transgenes and other genome features developed in mice to model this disease.
     Disease Term Transgenes and Other Genome Features Mouse Models
  dermoid cyst of ovary Tg(Amh-SMAD2*)#Jebu 1 model
  ovarian cancer Tg(Amhr2-SV40TAg)1Dcco 1 model
  ovarian cancer Tg(CAG-lacZ,-SV40)#Bcv 1 model
  polycystic ovary syndrome Tg(Cyp17a1-NGF)2456Oje 1 model