| Disease Term | Human Homologs | Mouse Homologs | Mouse Models | Homology Source | |||
  | GM1 gangliosidosis | GLB1* | Glb1* | 3 models | Alliance of Genome Resources | ||
| GM2 gangliosidosis, AB variant | GM2A* | Gm2a* | 1 model | Alliance of Genome Resources | |||
| Sandhoff disease | HEXB* | Hexb* | 9 models | Alliance of Genome Resources | |||
| Tay-Sachs disease | HEXA* | Hexa* | 3 models | Alliance of Genome Resources | |||
| | GM1 gangliosidosis type 1 | GLB1* | Glb1 | Alliance of Genome Resources | |||
| GM1 gangliosidosis type 2 | GLB1* | Glb1 | Alliance of Genome Resources | ||||
| GM1 gangliosidosis type 3 | GLB1* | Glb1 | Alliance of Genome Resources | ||||
| GM2 gangliosidosis | GM2A* | Gm2a | Alliance of Genome Resources | ||||
Excel File
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Transgenes and other genome features developed in mice to model this disease.
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| Disease Term | Transgenes and Other Genome Features | Mouse Models | |
| Sandhoff disease | Tg(SYN1-tTA2S,tetO-Hexb)#Tjsa | 1 model | |
| Sandhoff disease | Tg(Hexb-tTA2S,tetO-Hexb)#Tjsa | 1 model | |