Disease Term | Human Homologs | Mouse Homologs | Mouse Models | Homology Source | |||
schizophrenia | AKT1* | Akt1* | 1 model | Alliance of Genome Resources | |||
schizophrenia | CHRNA7*, CHRFAM7A | Chrna7* | 1 model | Alliance of Genome Resources | |||
schizophrenia | DISC1* | Disc1* | 7 models | Alliance of Genome Resources | |||
schizophrenia | DTNBP1* | Dtnbp1* | 2 models | Alliance of Genome Resources | |||
schizophrenia | NCSTN* | Ncstn* | 1 model | Alliance of Genome Resources | |||
schizoaffective disorder | GRIA1 | Gria1* | 2 models | Alliance of Genome Resources | |||
schizophrenia | NRXN1 | Nrxn1* | 1 model | Alliance of Genome Resources | |||
schizophrenia | AVPR1A | Avpr1a* | 1 model | Alliance of Genome Resources | |||
schizophrenia | BACE1 | Bace1* | 1 model | Alliance of Genome Resources | |||
schizophrenia | CHST3 | Chst3* | 1 model | Alliance of Genome Resources | |||
schizophrenia | ckr* | 1 model | |||||
schizophrenia | CPLX2 | Cplx2* | 1 model | Alliance of Genome Resources | |||
schizophrenia | CSMD1 | Csmd1* | 1 model | Alliance of Genome Resources | |||
schizophrenia | CTSC | Ctsc* | 1 model | Alliance of Genome Resources | |||
schizophrenia | GNAS | Gnas* | 1 model | Alliance of Genome Resources | |||
schizophrenia | GRIN1 | Grin1* | 1 model | Alliance of Genome Resources | |||
schizophrenia | GRM5 | Grm5* | 1 model | Alliance of Genome Resources | |||
schizophrenia | HIVEP2 | Hivep2* | 2 models | Alliance of Genome Resources | |||
schizophrenia | KIF3B | Kif3b* | 1 model | Alliance of Genome Resources | |||
schizophrenia | LRRTM1 | Lrrtm1* | 1 model | Alliance of Genome Resources | |||
schizophrenia | MAGI2 | Magi2* | 1 model | Alliance of Genome Resources | |||
schizophrenia | MAP2K7 | Map2k7* | 1 model | Alliance of Genome Resources | |||
schizophrenia | MAP6 | Map6* | 3 models | Alliance of Genome Resources | |||
schizophrenia | MDK | Mdk* | 1 model | Alliance of Genome Resources | |||
schizophrenia | NLGN2 | Nlgn2* | 1 model | Alliance of Genome Resources | |||
schizophrenia | NR4A2 | Nr4a2* | 1 model | Alliance of Genome Resources | |||
schizophrenia | NRG1 | Nrg1* | 1 model | Alliance of Genome Resources | |||
schizophrenia | NRG3 | Nrg3* | 1 model | Alliance of Genome Resources | |||
schizophrenia | PDGFRB | Pdgfrb* | 1 model | Alliance of Genome Resources | |||
schizophrenia | PLCB1 | Plcb1* | 1 model | Alliance of Genome Resources | |||
schizophrenia | PPARA | Ppara* | 1 model | Alliance of Genome Resources | |||
schizophrenia | PPM1G | Ppm1g* | 1 model | Alliance of Genome Resources | |||
schizophrenia | PPP3R1 | Ppp3r1* | 1 model | Alliance of Genome Resources | |||
schizophrenia | RELN | Reln* | 2 models | Alliance of Genome Resources | |||
schizophrenia | SETD1A | Setd1a* | 1 model | Alliance of Genome Resources | |||
schizophrenia | SHANK3 | Shank3* | 1 model | Alliance of Genome Resources | |||
schizophrenia | SLC6A1 | Slc6a1* | 1 model | Alliance of Genome Resources | |||
schizophrenia | SLC6A3 | Slc6a3* | 1 model | Alliance of Genome Resources | |||
schizophrenia | SNAP25 | Snap25* | 1 model | Alliance of Genome Resources | |||
schizophrenia | SP4 | Sp4* | 1 model | Alliance of Genome Resources | |||
schizophrenia | SRGAP3 | Srgap3* | 1 model | Alliance of Genome Resources | |||
schizophrenia | SRR | Srr* | 2 models | Alliance of Genome Resources | |||
schizophrenia | SYNGAP1 | Syngap1* | 1 model | Alliance of Genome Resources | |||
schizophrenia | TAAR1 | Taar1* | 1 model | Alliance of Genome Resources | |||
schizophrenia | TCF4 | Tcf4* | 1 model | Alliance of Genome Resources | |||
schizophrenia | YWHAZ | Ywhaz* | 1 model | Alliance of Genome Resources | |||
schizophrenia | ZNF521 | Zfp521* | 1 model | Alliance of Genome Resources | |||
schizophrenia | ZNF804A | Zfp804a* | 1 model | Alliance of Genome Resources | |||
schizophrenia | ZIC2 | Zic2* | 1 model | Alliance of Genome Resources | |||
alcoholic psychosis | HTR2A* | Htr2a | Alliance of Genome Resources | ||||
alcohol-induced mental disorder | ANKK1* | Ankk1 | Alliance of Genome Resources | ||||
alcohol-induced mental disorder | DRD2* | Drd2 | Alliance of Genome Resources | ||||
drug psychosis | GAD2* | Gad2 | Alliance of Genome Resources | ||||
drug psychosis | GAD1* | Gad1 | Alliance of Genome Resources | ||||
drug psychosis | OPRM1* | Oprm1 | Alliance of Genome Resources | ||||
paranoid schizophrenia | KCNN3* | Kcnn3 | Alliance of Genome Resources | ||||
paranoid schizophrenia | HSPA1A*, HSPA1B | Hspa1a, Hspa1b | Alliance of Genome Resources | ||||
paranoid schizophrenia | PAX6* | Pax6 | Alliance of Genome Resources | ||||
psychotic disorder | GDI1* | Gdi1 | Alliance of Genome Resources | ||||
psychotic disorder | DISC1* | Disc1 | Alliance of Genome Resources | ||||
psychotic disorder | NRG1* | Nrg1 | Alliance of Genome Resources | ||||
schizophrenia | CLDN5* | Cldn5 | 1 model | Alliance of Genome Resources | |||
schizophrenia | CNP* | Cnp | Alliance of Genome Resources | ||||
schizophrenia | CNR1* | Cnr1 | Alliance of Genome Resources | ||||
schizophrenia | CNTNAP2* | Cntnap2 | Alliance of Genome Resources | ||||
schizophrenia | COMT* | Comt | 1 model | Alliance of Genome Resources | |||
schizophrenia | CTNND2* | Ctnnd2 | Alliance of Genome Resources | ||||
schizophrenia | CYFIP1* | Cyfip1 | Alliance of Genome Resources | ||||
schizophrenia | DAO* | Dao | Alliance of Genome Resources | ||||
schizophrenia | DAOA* | ||||||
schizophrenia | DISC2* | ||||||
schizophrenia | DNMT3B* | Dnmt3b | Alliance of Genome Resources | ||||
schizophrenia | DRD3* | Drd3 | Alliance of Genome Resources | ||||
schizophrenia | FGF1* | Fgf1 | Alliance of Genome Resources | ||||
schizophrenia | FOXP1* | Foxp1 | Alliance of Genome Resources | ||||
schizophrenia | FOXP2* | Foxp2 | Alliance of Genome Resources | ||||
schizophrenia | FYN* | Fyn | Alliance of Genome Resources | ||||
schizophrenia | FZD3* | Fzd3 | Alliance of Genome Resources | ||||
schizophrenia | GAD1* | Gad1 | Alliance of Genome Resources | ||||
schizophrenia | GAD2* | Gad2 | Alliance of Genome Resources | ||||
schizophrenia | GRIA4* | Gria4 | Alliance of Genome Resources | ||||
schizophrenia | GRIN2A* | Grin2a | Alliance of Genome Resources | ||||
schizophrenia | GRIN2B* | Grin2b | Alliance of Genome Resources | ||||
schizophrenia | GRM8* | Grm8 | Alliance of Genome Resources | ||||
schizophrenia | GSK3B* | Gsk3b | Alliance of Genome Resources | ||||
schizophrenia | GSTM1*, GSTM5 | Gstm1, Gstm2, Gstm3, Gstm6 | Alliance of Genome Resources | ||||
schizophrenia | HPS4* | Hps4 | Alliance of Genome Resources | ||||
schizophrenia | HSPA1A*, HSPA1B* | Hspa1a, Hspa1b | Alliance of Genome Resources | ||||
schizophrenia | HSPA1L* | Hspa1l | Alliance of Genome Resources | ||||
schizophrenia | HTR2A* | Htr2a | Alliance of Genome Resources | ||||
schizophrenia | HTR2C* | Htr2c | Alliance of Genome Resources | ||||
schizophrenia | IL10* | Il10 | Alliance of Genome Resources | ||||
schizophrenia | IMPA2* | Impa2 | Alliance of Genome Resources | ||||
schizophrenia | ITGA8* | Itga8 | Alliance of Genome Resources | ||||
schizophrenia | KCNN3* | Kcnn3 | Alliance of Genome Resources | ||||
schizophrenia | KIF5C* | Kif5c | Alliance of Genome Resources | ||||
schizophrenia | L1CAM* | L1cam | Alliance of Genome Resources | ||||
schizophrenia | LRP8* | Lrp8 | Alliance of Genome Resources | ||||
schizophrenia | MBD2* | Mbd2 | Alliance of Genome Resources | ||||
schizophrenia | MED15* | Med15 | Alliance of Genome Resources | ||||
schizophrenia | MIR30E* | Mir30e | Alliance of Genome Resources | ||||
schizophrenia | ND4* | mt-Nd4 | Alliance of Genome Resources | ||||
schizophrenia | MTHFR* | Mthfr | Alliance of Genome Resources | ||||
schizophrenia | NOTCH4* | Notch4 | Alliance of Genome Resources | ||||
schizophrenia | NTRK1* | Ntrk1 | Alliance of Genome Resources | ||||
schizophrenia | NTSR1* | Ntsr1 | Alliance of Genome Resources | ||||
schizophrenia | OPRM1* | Oprm1 | Alliance of Genome Resources | ||||
schizophrenia | PAICS* | Paics | Alliance of Genome Resources | ||||
schizophrenia | PAK1* | Pak1 | Alliance of Genome Resources | ||||
schizophrenia | PIK3CD* | Pik3cd | Alliance of Genome Resources | ||||
schizophrenia | PPP1R1B* | Ppp1r1b | Alliance of Genome Resources | ||||
schizophrenia | PPP3CC* | Ppp3cc | Alliance of Genome Resources | ||||
schizophrenia | RTN4R* | Rtn4r | 1 model | Alliance of Genome Resources | |||
schizophrenia | S100B* | S100b | Alliance of Genome Resources | ||||
schizophrenia | SLC18A1* | Slc18a1 | Alliance of Genome Resources | ||||
schizophrenia | SLC25A27* | Slc25a27 | Alliance of Genome Resources | ||||
schizophrenia | SYN2* | Syn2 | Alliance of Genome Resources | ||||
schizophrenia | TAP1* | Tap1 | Alliance of Genome Resources | ||||
schizophrenia | TBP* | Tbp | Alliance of Genome Resources | ||||
schizophrenia | TNF* | Tnf | Alliance of Genome Resources | ||||
schizophrenia | TPH1* | Tph1 | Alliance of Genome Resources | ||||
schizophrenia | TRPV3* | Trpv3 | Alliance of Genome Resources | ||||
schizophrenia | UFD1* | Ufd1 | 1 model | Alliance of Genome Resources | |||
schizophrenia | AGER* | Ager | Alliance of Genome Resources | ||||
schizophrenia | ANK3* | Ank3 | Alliance of Genome Resources | ||||
schizophrenia | APOL2*, APOL4*, APOL1, APOL3 | Apol7a, Apol7b, Apol7c, Apol7e, Apol8, Apol9a, Apol9b, Apol10a, Apol10b, Apol11a, Apol11b | Alliance of Genome Resources | ||||
schizophrenia | ARHGAP18* | Arhgap18 | Alliance of Genome Resources | ||||
schizophrenia | ATN1* | Atn1 | Alliance of Genome Resources | ||||
schizophrenia | B3GAT2* | B3gat2 | Alliance of Genome Resources | ||||
schizophrenia | BCL11A* | Bcl11a | Alliance of Genome Resources | ||||
schizophrenia | BRD1* | Brd1 | Alliance of Genome Resources | ||||
schizophrenia | CACNA1I* | Cacna1i | Alliance of Genome Resources | ||||
schizophrenia | CHI3L1* | Chi3l1 | Alliance of Genome Resources | ||||
schizophrenia | CHL1* | Chl1 | Alliance of Genome Resources | ||||
schizophrenia | CHRM2* | Chrm2 | Alliance of Genome Resources | ||||
schizophrenia 15 | SHANK3* | Shank3 | Alliance of Genome Resources | ||||
schizophrenia 18 | SLC1A1* | Slc1a1 | Alliance of Genome Resources | ||||
schizophrenia 19 | RBM12* | Rbm12 | Alliance of Genome Resources | ||||
schizophrenia 4 | PRODH* | Prodh | Alliance of Genome Resources | ||||
schizophrenia 6 | NRG1* | Nrg1 | Alliance of Genome Resources | ||||
schizophrenia 9 | DISC1* | Disc1 | Alliance of Genome Resources | ||||
subacute delirium | ACHE* | Ache | Alliance of Genome Resources |
Transgenes and other genome features developed in mice to model this disease.
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Disease Term | Transgenes and Other Genome Features | Mouse Models | |
schizophrenia | Tg(Camk2a-DISC1)10Asaw | 1 model | |
schizophrenia | Tg(Camk2a-DISC1)37Asaw | 2 models | |
schizophrenia | Tg(Camk2a-ESR1/Disc1*)2698.1Sva | 1 model | |
schizophrenia | Tg(Camk2a-Magi2)1Shlee | 1 model | |
schizophrenia | Tg(Disc1/EGFP)M19Sshe | 1 model | |
schizophrenia | Tg(tetO-Gnas)1593Mpke | 1 model | |
schizophrenia | Tg(tetO-HMOX1)6Hyms | 1 model | |
schizophrenia | Tg(tetO-NRG1_i4)6Ajla | 1 model | |
schizophrenia | Tg(Thy1-Tcf4)1Mjro | 1 model | |
schizophrenia | Del(16Dgcr2-Hira)3Aam | 1 model | |
schizophrenia 9 | Tg(tetO-DISC1*)70Plet | 1 model | |
schizophrenia 9 | Tg(tetO-DISC1*)1001Plet | 1 model |