Disease Term | Human Homologs | Mouse Homologs | Mouse Models | Homology Source | |||
Mahvash Disease | GCGR* | Gcgr* | 1 model | Alliance of Genome Resources | |||
annular pancreas | GDF1 | Gdf1* | 1 model | Alliance of Genome Resources | |||
annular pancreas | IHH | Ihh* | 1 model | Alliance of Genome Resources | |||
pancreatic carcinoma | KRAS | Kras* | 13 models | Alliance of Genome Resources | |||
pancreatic carcinoma | MYC | Myc*, Bmyc | 3 models | Alliance of Genome Resources | |||
pancreatitis | Prss3b* | 1 model | |||||
pancreatitis | CPA1 | Cpa1* | 1 model | Alliance of Genome Resources | |||
acute necrotizing pancreatitis | IL1RN* | Il1rn | Alliance of Genome Resources | ||||
acute pancreatitis | IL10* | Il10 | Alliance of Genome Resources | ||||
acute pancreatitis | F7* | F7 | Alliance of Genome Resources | ||||
alcoholic pancreatitis | CFTR* | Cftr | Alliance of Genome Resources | ||||
alcoholic pancreatitis | UGT1A7*, UGT1A8, UGT1A9, UGT1A10 | Ugt1a7c, Ugt1a8, Ugt1a9, Ugt1a10 | Alliance of Genome Resources | ||||
autoimmune pancreatitis | HLA-DQB1*, HLA-DQB2 | H2-Ab1 | Alliance of Genome Resources | ||||
exocrine pancreatic insufficiency | CFTR* | Cftr | Alliance of Genome Resources | ||||
hyperinsulinism | AGT* | Agt | Alliance of Genome Resources | ||||
hyperinsulinism | GCK* | Gck | Alliance of Genome Resources | ||||
hyperinsulinism | GLUD1*, GLUD2 | Glud1 | Alliance of Genome Resources | ||||
hyperinsulinism | IL6* | Il6 | Alliance of Genome Resources | ||||
hyperinsulinism | INS* | Ins1, Ins2 | Alliance of Genome Resources | ||||
hyperinsulinism | KCNJ11* | Kcnj11 | Alliance of Genome Resources | ||||
hyperinsulinism | LTA* | Lta | Alliance of Genome Resources | ||||
hyperinsulinism | MTTP* | Mttp | Alliance of Genome Resources | ||||
hyperinsulinism | PARL* | Parl | Alliance of Genome Resources | ||||
hyperinsulinism | PTPRF* | Ptprf | Alliance of Genome Resources | ||||
hyperinsulinism | CDKN1C* | Cdkn1c | Alliance of Genome Resources | ||||
hyperinsulinism | ABCC8* | Abcc8 | Alliance of Genome Resources | ||||
insulinoma | INS* | Ins1, Ins2 | Alliance of Genome Resources | ||||
islet cell tumor | DAXX* | Daxx | Alliance of Genome Resources | ||||
opisthorchiasis | ACTR3* | Actr3 | Alliance of Genome Resources | ||||
pancreas disease | MSLN* | Msln | Alliance of Genome Resources | ||||
pancreas disease | HNF1B* | Hnf1b | Alliance of Genome Resources | ||||
pancreatic acinar cell adenocarcinoma | BRAF* | Braf | Alliance of Genome Resources | ||||
pancreatic adenocarcinoma | CDK4* | Cdk4 | Alliance of Genome Resources | ||||
pancreatic adenocarcinoma | SMAD7* | Smad7 | Alliance of Genome Resources | ||||
pancreatic adenocarcinoma | RALBP1* | Ralbp1 | Alliance of Genome Resources | ||||
pancreatic adenocarcinoma | RALB* | Ralb | Alliance of Genome Resources | ||||
pancreatic adenocarcinoma | RAF1* | Raf1 | Alliance of Genome Resources | ||||
pancreatic adenocarcinoma | RAC1* | Rac1 | Alliance of Genome Resources | ||||
pancreatic adenocarcinoma | MAPK10* | Mapk10 | Alliance of Genome Resources | ||||
pancreatic adenocarcinoma | MAPK9* | Mapk9 | Alliance of Genome Resources | ||||
pancreatic adenocarcinoma | MAP2K1* | Map2k1 | Alliance of Genome Resources | ||||
pancreatic adenocarcinoma | JAK1* | Jak1 | Alliance of Genome Resources | ||||
pancreatic adenocarcinoma | GSTT1* | Gstt1 | Alliance of Genome Resources | ||||
pancreatic adenocarcinoma | E2F1* | E2f1 | Alliance of Genome Resources | ||||
pancreatic adenocarcinoma | CXCR4* | Cxcr4 | Alliance of Genome Resources | ||||
pancreatic adenocarcinoma | CDK6* | Cdk6 | Alliance of Genome Resources | ||||
pancreatic adenocarcinoma | CDKN2A* | Cdkn2a | Alliance of Genome Resources | ||||
pancreatic adenosquamous carcinoma | TGFB2* | Tgfb2 | Alliance of Genome Resources | ||||
pancreatic agenesis | PTF1A* | Ptf1a | Alliance of Genome Resources | ||||
pancreatic agenesis | PDX1* | Pdx1 | Alliance of Genome Resources | ||||
pancreatic cancer | IL2* | Il2 | Alliance of Genome Resources | ||||
pancreatic cancer | IL4* | Il4 | Alliance of Genome Resources | ||||
pancreatic cancer | IL10* | Il10 | Alliance of Genome Resources | ||||
pancreatic cancer | IL13* | Il13 | Alliance of Genome Resources | ||||
pancreatic cancer | IL13RA2* | Il13ra2 | Alliance of Genome Resources | ||||
pancreatic cancer | ILK* | Ilk | Alliance of Genome Resources | ||||
pancreatic cancer | INS* | Ins1, Ins2 | Alliance of Genome Resources | ||||
pancreatic cancer | ITGA4* | Itga4 | Alliance of Genome Resources | ||||
pancreatic cancer | ITGA9* | Itga9 | Alliance of Genome Resources | ||||
pancreatic cancer | ITGA11* | Itga11 | Alliance of Genome Resources | ||||
pancreatic cancer | KDR* | Kdr | Alliance of Genome Resources | ||||
pancreatic cancer | KRAS* | Kras | Alliance of Genome Resources | ||||
pancreatic cancer | L1CAM* | L1cam | Alliance of Genome Resources | ||||
pancreatic cancer | LIG3* | Lig3 | Alliance of Genome Resources | ||||
pancreatic cancer | LIG4* | Lig4 | Alliance of Genome Resources | ||||
pancreatic cancer | LUM* | Lum | Alliance of Genome Resources | ||||
pancreatic cancer | MANF* | Manf | Alliance of Genome Resources | ||||
pancreatic cancer | MAP2K4* | Map2k4 | Alliance of Genome Resources | ||||
pancreatic cancer | MEN1* | Men1 | Alliance of Genome Resources | ||||
pancreatic cancer | MKI67* | Mki67 | Alliance of Genome Resources | ||||
pancreatic cancer | MPO* | Mpo | Alliance of Genome Resources | ||||
pancreatic cancer | MSLN* | Msln | Alliance of Genome Resources | ||||
pancreatic cancer | MTHFR* | Mthfr | Alliance of Genome Resources | ||||
pancreatic cancer | MTR* | Mtr | Alliance of Genome Resources | ||||
pancreatic cancer | MTRR* | Mtrr | Alliance of Genome Resources | ||||
pancreatic cancer | MUC1* | Muc1 | Alliance of Genome Resources | ||||
pancreatic cancer | MUC4* | Muc4 | Alliance of Genome Resources | ||||
pancreatic cancer | NAP1L1* | Nap1l1 | Alliance of Genome Resources | ||||
pancreatic cancer | NAT1*, NAT2* | Nat1, Nat2, Nat3 | Alliance of Genome Resources | ||||
pancreatic cancer | NCAM1* | Ncam1 | Alliance of Genome Resources | ||||
pancreatic cancer | NUF2* | Nuf2 | Alliance of Genome Resources | ||||
pancreatic cancer | OGG1* | Ogg1 | Alliance of Genome Resources | ||||
pancreatic cancer | PALB2* | Palb2 | Alliance of Genome Resources | ||||
pancreatic cancer | PALLD* | Palld | Alliance of Genome Resources | ||||
pancreatic cancer | PDGFRA* | Pdgfra | Alliance of Genome Resources | ||||
pancreatic cancer | PPARG* | Pparg | Alliance of Genome Resources | ||||
pancreatic cancer | PTGS2* | Ptgs2 | Alliance of Genome Resources | ||||
pancreatic cancer | RABL3* | Rabl3 | Alliance of Genome Resources | ||||
pancreatic cancer | RAD54L* | Rad54l | Alliance of Genome Resources | ||||
pancreatic cancer | RECQL* | Recql | Alliance of Genome Resources | ||||
pancreatic cancer | RRM2* | Rrm2 | Alliance of Genome Resources | ||||
pancreatic cancer | RUNX3* | Runx3 | Alliance of Genome Resources | ||||
pancreatic cancer | RXRA* | Rxra | Alliance of Genome Resources | ||||
pancreatic cancer | SEL1L* | Sel1l | Alliance of Genome Resources | ||||
pancreatic cancer | SMAD3* | Smad3 | Alliance of Genome Resources | ||||
pancreatic cancer | SMAD4* | Smad4 | Alliance of Genome Resources | ||||
pancreatic cancer | SMO* | Smo | Alliance of Genome Resources | ||||
pancreatic cancer | SNW1* | Snw1 | Alliance of Genome Resources | ||||
pancreatic cancer | SOD2* | Sod2 | Alliance of Genome Resources | ||||
pancreatic cancer | SPP1* | Spp1 | Alliance of Genome Resources | ||||
pancreatic cancer | STK11* | Stk11 | Alliance of Genome Resources | ||||
pancreatic cancer | TCF7L2* | Tcf7l2 | Alliance of Genome Resources | ||||
pancreatic cancer | TGFBR2* | Tgfbr2 | Alliance of Genome Resources | ||||
pancreatic cancer | THBS1* | Thbs1 | Alliance of Genome Resources | ||||
pancreatic cancer | TP53* | Trp53 | Alliance of Genome Resources | ||||
pancreatic cancer | TYMP* | Tymp | Alliance of Genome Resources | ||||
pancreatic cancer | UGT1A7*, UGT1A8, UGT1A9, UGT1A10 | Ugt1a7c, Ugt1a8, Ugt1a9, Ugt1a10 | Alliance of Genome Resources | ||||
pancreatic cancer | VHL*, VHLL | Vhl | Alliance of Genome Resources | ||||
pancreatic cancer | WNT9A* | Wnt9a | Alliance of Genome Resources | ||||
pancreatic cancer | XPC* | Xpc | Alliance of Genome Resources | ||||
pancreatic cancer | XRCC1* | Xrcc1 | Alliance of Genome Resources | ||||
pancreatic cancer | XRCC2* | Xrcc2 | Alliance of Genome Resources | ||||
pancreatic cancer | XRCC3* | Xrcc3 | Alliance of Genome Resources | ||||
pancreatic cancer | POLB* | Polb | Alliance of Genome Resources | ||||
pancreatic cancer | ABO* | Abo | Alliance of Genome Resources | ||||
pancreatic cancer | ACVR1B* | Acvr1b | Alliance of Genome Resources | ||||
pancreatic cancer | ADH1C*, ADH1A, ADH1B | Adh1 | Alliance of Genome Resources | ||||
pancreatic cancer | ADM* | Adm | Alliance of Genome Resources | ||||
pancreatic cancer | AKT1* | Akt1 | Alliance of Genome Resources | ||||
pancreatic cancer | ALDH2* | Aldh2 | Alliance of Genome Resources | ||||
pancreatic cancer | ALOX5* | Alox5 | Alliance of Genome Resources | ||||
pancreatic cancer | ANXA1* | Anxa1 | Alliance of Genome Resources | ||||
pancreatic cancer | APC* | Apc | Alliance of Genome Resources | ||||
pancreatic cancer | ARPC1A* | Arpc1a | Alliance of Genome Resources | ||||
pancreatic cancer | ATM* | Atm | Alliance of Genome Resources | ||||
pancreatic cancer | ATR* | Atr | Alliance of Genome Resources | ||||
pancreatic cancer | BAD* | Bad | Alliance of Genome Resources | ||||
pancreatic cancer | BCL2L1* | Bcl2l1 | Alliance of Genome Resources | ||||
pancreatic cancer | BID* | Bid | Alliance of Genome Resources | ||||
pancreatic cancer | BRAF* | Braf | Alliance of Genome Resources | ||||
pancreatic cancer | BRCA1* | Brca1 | Alliance of Genome Resources | ||||
pancreatic cancer | BRCA2* | Brca2 | Alliance of Genome Resources | ||||
pancreatic cancer | CAPN10* | Capn10 | Alliance of Genome Resources | ||||
pancreatic cancer | CASP8* | Casp8 | Alliance of Genome Resources | ||||
pancreatic cancer | CASP9* | Casp9 | Alliance of Genome Resources | ||||
pancreatic cancer | CCKBR* | Cckbr | Alliance of Genome Resources | ||||
pancreatic cancer | CCND1* | Ccnd1 | Alliance of Genome Resources | ||||
pancreatic cancer | CCNG1* | Ccng1 | Alliance of Genome Resources | ||||
pancreatic cancer | CDKN2A* | Cdkn2a | Alliance of Genome Resources | ||||
pancreatic cancer | CFTR* | Cftr | Alliance of Genome Resources | ||||
pancreatic cancer | CHEK1* | Chek1 | Alliance of Genome Resources | ||||
pancreatic cancer | CLDN4* | Cldn4, Cldn13 | Alliance of Genome Resources | ||||
pancreatic cancer | CYCS* | Cycs | Alliance of Genome Resources | ||||
pancreatic cancer | CYP17A1* | Cyp17a1 | Alliance of Genome Resources | ||||
pancreatic cancer | DPYD* | Dpyd | Alliance of Genome Resources | ||||
pancreatic cancer | EGFR* | Egfr | Alliance of Genome Resources | ||||
pancreatic cancer | EPHA3* | Epha3 | Alliance of Genome Resources | ||||
pancreatic cancer | ERCC1* | Ercc1 | Alliance of Genome Resources | ||||
pancreatic cancer | ERCC2* | Ercc2 | Alliance of Genome Resources | ||||
pancreatic cancer | ERCC4* | Ercc4 | Alliance of Genome Resources | ||||
pancreatic cancer | FANCA* | Fanca | Alliance of Genome Resources | ||||
pancreatic cancer | FANCC* | Fancc | Alliance of Genome Resources | ||||
pancreatic cancer | FANCG* | Fancg | Alliance of Genome Resources | ||||
pancreatic cancer | FASLG* | Fasl | Alliance of Genome Resources | ||||
pancreatic cancer | FGF2* | Fgf2 | Alliance of Genome Resources | ||||
pancreatic cancer | GSTP1* | Gstp1, Gstp2, Gstp3, Gstp-ps | Alliance of Genome Resources | ||||
pancreatic cancer | HS3ST2* | Hs3st2 | Alliance of Genome Resources | ||||
pancreatic cancer | HSPB1* | Hspb1 | Alliance of Genome Resources | ||||
pancreatic cancer | IGF1* | Igf1 | Alliance of Genome Resources | ||||
pancreatic cancer | IGF1R* | Igf1r | Alliance of Genome Resources | ||||
pancreatic cancer | IL1B* | Il1b | Alliance of Genome Resources | ||||
pancreatic carcinoma | KDR* | Kdr | Alliance of Genome Resources | ||||
pancreatic carcinoma | CDKN2A* | Cdkn2a | 1 model | Alliance of Genome Resources | |||
pancreatic ductal adenocarcinoma | TGFBR1* | Tgfbr1 | Alliance of Genome Resources | ||||
pancreatic ductal adenocarcinoma | PIK3R2* | Pik3r2 | Alliance of Genome Resources | ||||
pancreatic ductal adenocarcinoma | MIR494* | Mir494 | Alliance of Genome Resources | ||||
pancreatic ductal adenocarcinoma | GOT1* | Got1 | Alliance of Genome Resources | ||||
pancreatic ductal adenocarcinoma | E2F1* | E2f1 | Alliance of Genome Resources | ||||
pancreatic ductal adenocarcinoma | CCND1* | Ccnd1 | Alliance of Genome Resources | ||||
pancreatic ductal adenocarcinoma | CALR* | Calr | Alliance of Genome Resources | ||||
pancreatic ductal carcinoma | MDM2* | Mdm2 | Alliance of Genome Resources | ||||
pancreatic ductal carcinoma | THBS1* | Thbs1 | Alliance of Genome Resources | ||||
pancreatic ductal carcinoma | SMO* | Smo | Alliance of Genome Resources | ||||
pancreatic ductal carcinoma | PMS1* | Pms1 | Alliance of Genome Resources | ||||
pancreatic ductal carcinoma | MUC1* | Muc1 | Alliance of Genome Resources | ||||
pancreatic ductal carcinoma | MSLN* | Msln | Alliance of Genome Resources | ||||
pancreatic ductal carcinoma | MGMT* | Mgmt | Alliance of Genome Resources | ||||
pancreatic ductal carcinoma | MEN1* | Men1 | Alliance of Genome Resources | ||||
pancreatic ductal carcinoma | VHL*, VHLL | Vhl | Alliance of Genome Resources | ||||
pancreatic ductal carcinoma | MAPK3* | Mapk3 | Alliance of Genome Resources | ||||
pancreatic ductal carcinoma | IL4* | Il4 | Alliance of Genome Resources | ||||
pancreatic ductal carcinoma | HEATR1* | Heatr1 | Alliance of Genome Resources | ||||
pancreatic ductal carcinoma | GSTP1* | Gstp1, Gstp2, Gstp3, Gstp-ps | Alliance of Genome Resources | ||||
pancreatic ductal carcinoma | FASLG* | Fasl | Alliance of Genome Resources | ||||
pancreatic ductal carcinoma | CDK6* | Cdk6 | Alliance of Genome Resources | ||||
pancreatic ductal carcinoma | CD40* | Cd40 | Alliance of Genome Resources | ||||
pancreatic endocrine carcinoma | PGF* | Pgf | Alliance of Genome Resources | ||||
pancreatic endocrine carcinoma | MGMT* | Mgmt | Alliance of Genome Resources | ||||
pancreatic endocrine carcinoma | DAXX* | Daxx | Alliance of Genome Resources | ||||
pancreatic intraductal papillary-mucinous neoplasm | TP53* | Trp53 | Alliance of Genome Resources | ||||
pancreatic intraductal papillary-mucinous neoplasm | AKT1* | Akt1 | Alliance of Genome Resources | ||||
pancreatic mucinous cystadenoma | KRAS* | Kras | Alliance of Genome Resources | ||||
pancreatitis | SERPING1* | Serping1 | Alliance of Genome Resources | ||||
pancreatitis | PRSS1*, PRSS2, PRSS3, PRSS3P2 | Prss1, Prss1l, Prss2, Prss3, Prss3l, Try4, Try5, Try10 | Alliance of Genome Resources | ||||
pancreatitis | CCL5* | Ccl5 | Alliance of Genome Resources | ||||
pancreatitis | SPINK1* | Spink1 | Alliance of Genome Resources | ||||
pancreatitis | CCL2*, CCL13 | Ccl2, Ccl12 | Alliance of Genome Resources |
Transgenes and other genome features developed in mice to model this disease.
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Disease Term | Transgenes and Other Genome Features | Mouse Models | |
insulinoma | Tg(RIP1-Tag)2Dh | 1 model | |
pancreatic carcinoma | Tg(RIR-Tag)87Dh | 1 model | |
pancreatic carcinoma | Tg(RIP1-Tag)2Dh | 3 models | |
pancreatic carcinoma | Tg(Ins2-Tag*,-flpe)#Gne | 2 models | |
pancreatic carcinoma | Tg(Ela1-TAg)19Bri | 1 model | |
pancreatic carcinoma | Tg(Ela1-TAg)18Bri | 1 model | |
pancreatic carcinoma | Tg(Ela1-Myc)160Bri | 1 model | |
pancreatic carcinoma | Tg(Ela1-Myc)159Bri | 1 model | |
pancreatic carcinoma | Tg(Ela1-Myc)158Bri | 1 model | |
pancreatic carcinoma | Tg(Cela1-luc,Cela1-TAg)#Nzh | 1 model | |
pancreatic carcinoma | Tg(tetO-MYC)36Bop | 1 model |