| Disease Term | Human Homologs | Mouse Homologs | Mouse Models | Homology Source | |||
  | atopic dermatitis | IL4* | Il4* | 1 model | Alliance of Genome Resources | ||
| atopic dermatitis | IL13* | Il13* | 1 model | Alliance of Genome Resources | |||
| atopic dermatitis | IL18* | Il18* | 1 model | Alliance of Genome Resources | |||
| epidermolysis bullosa simplex | KRT14* | Krt14* | 2 models | Alliance of Genome Resources | |||
| epidermolysis bullosa simplex Ogna type | PLEC* | Plec* | 4 models | Alliance of Genome Resources | |||
| junctional epidermolysis bullosa | COL17A1* | Col17a1* | 4 models | Alliance of Genome Resources | |||
| junctional epidermolysis bullosa | LAMA3* | Lama3* | 1 model | Alliance of Genome Resources | |||
| junctional epidermolysis bullosa with pyloric atresia | ITGB4* | Itgb4* | 1 model | Alliance of Genome Resources | |||
| | atopic dermatitis | ADAM17 | Adam17* | 1 model | Alliance of Genome Resources | ||
| atopic dermatitis | CASP8 | Casp8* | 1 model | Alliance of Genome Resources | |||
| atopic dermatitis | CTSE | Ctse* | 1 model | Alliance of Genome Resources | |||
| atopic dermatitis | NFKBIA | Nfkbia* | 1 model | Alliance of Genome Resources | |||
| atopic dermatitis | NFKBIZ | Nfkbiz* | 1 model | Alliance of Genome Resources | |||
| atopic dermatitis | Noa* | 1 model | |||||
| atopic dermatitis | RELB | Relb* | 1 model | Alliance of Genome Resources | |||
| atopic dermatitis | SHARPIN | Sharpin* | 1 model | Alliance of Genome Resources | |||
| atopic dermatitis | TMEM79 | Tmem79* | 2 models | Alliance of Genome Resources | |||
| atopic dermatitis | TRAF3IP2 | Traf3ip2* | 5 models | Alliance of Genome Resources | |||
| atopic dermatitis | TRPV3 | Trpv3* | 1 model | Alliance of Genome Resources | |||
| atopic dermatitis | TSLP | Tslp* | 1 model | Alliance of Genome Resources | |||
| atopic dermatitis | WASL | Wasl* | 1 model | Alliance of Genome Resources | |||
| atopic dermatitis 2 | Flg* | 1 model | |||||
| epidermolysis bullosa simplex Dowling-Meara type | KRT14 | Krt14* | 3 models | Alliance of Genome Resources | |||
| epidermolysis bullosa simplex Dowling-Meara type | KRT5 | Krt5* | 1 model | Alliance of Genome Resources | |||
| junctional epidermolysis bullosa Herlitz type | LAMC2 | Lamc2* | 1 model | Alliance of Genome Resources | |||
| junctional epidermolysis bullosa Herlitz type | ITGA6 | Itga6* | 1 model | Alliance of Genome Resources | |||
| junctional epidermolysis bullosa Herlitz type | LAMB3 | Lamb3* | 2 models | Alliance of Genome Resources | |||
| junctional epidermolysis bullosa non-Herlitz type | ITGB4 | Itgb4* | 1 model | Alliance of Genome Resources | |||
| junctional epidermolysis bullosa non-Herlitz type | COL17A1 | Col17a1* | 1 model | Alliance of Genome Resources | |||
| junctional epidermolysis bullosa non-Herlitz type | LAMC2 | Lamc2* | 1 model | Alliance of Genome Resources | |||
| junctional epidermolysis bullosa non-Herlitz type | LAMB3 | Lamb3* | 1 model | Alliance of Genome Resources | |||
| junctional epidermolysis bullosa non-Herlitz type | LAMA3 | Lama3* | 1 model | Alliance of Genome Resources | |||
| pemphigus vulgaris | DSG3 | Dsg3* | 3 models | Alliance of Genome Resources | |||
| recessive dystrophic epidermolysis bullosa | GRIP1 | Grip1* | 1 model | Alliance of Genome Resources | |||
| recessive dystrophic epidermolysis bullosa | COL7A1 | Col7a1* | 5 models | Alliance of Genome Resources | |||
| | allergic contact dermatitis | CCR1* | Ccr1, Ccr1l1 | Alliance of Genome Resources | |||
| allergic contact dermatitis | TLR4* | Tlr4 | Alliance of Genome Resources | ||||
| allergic contact dermatitis | TAP2* | Tap2 | Alliance of Genome Resources | ||||
| allergic contact dermatitis | NAT1*, NAT2* | Nat1, Nat2, Nat3 | Alliance of Genome Resources | ||||
| allergic contact dermatitis | IL18BP* | Il18bp | Alliance of Genome Resources | ||||
| atopic dermatitis | CTLA4* | Ctla4 | Alliance of Genome Resources | ||||
| atopic dermatitis | APOE* | Apoe | Alliance of Genome Resources | ||||
| atopic dermatitis | BDNF* | Bdnf | Alliance of Genome Resources | ||||
| atopic dermatitis | CLDN1* | Cldn1 | Alliance of Genome Resources | ||||
| atopic dermatitis | CMA1* | Cma1 | Alliance of Genome Resources | ||||
| atopic dermatitis | DOCK8* | Dock8 | 1 model | Alliance of Genome Resources | |||
| atopic dermatitis | GSTM1*, GSTM5 | Gstm1, Gstm2, Gstm3, Gstm6 | Alliance of Genome Resources | ||||
| atopic dermatitis | GSTP1* | Gstp1, Gstp2, Gstp3, Gstp-ps | Alliance of Genome Resources | ||||
| atopic dermatitis | GSTT1* | Gstt1 | Alliance of Genome Resources | ||||
| atopic dermatitis | HAVCR1* | Havcr1, Timd2, Timd5, Timd6 | Alliance of Genome Resources | ||||
| atopic dermatitis | HNMT* | Hnmt | Alliance of Genome Resources | ||||
| atopic dermatitis | IL2* | Il2 | Alliance of Genome Resources | ||||
| atopic dermatitis | IL4R* | Il4ra | Alliance of Genome Resources | ||||
| atopic dermatitis | MBL2* | Mbl2 | Alliance of Genome Resources | ||||
| atopic dermatitis | MS4A2* | Ms4a2 | Alliance of Genome Resources | ||||
| atopic dermatitis | NAT2*, NAT1 | Nat1, Nat2, Nat3 | Alliance of Genome Resources | ||||
| atopic dermatitis | SELP* | Selp | Alliance of Genome Resources | ||||
| atopic dermatitis | SHOC2* | Shoc2 | Alliance of Genome Resources | ||||
| atopic dermatitis | TGFB1* | Tgfb1 | Alliance of Genome Resources | ||||
| atopic dermatitis | TLR2* | Tlr2 | Alliance of Genome Resources | ||||
| atopic dermatitis | TLR4* | Tlr4 | Alliance of Genome Resources | ||||
| atopic dermatitis | TNF* | Tnf | Alliance of Genome Resources | ||||
| atopic dermatitis | VDR* | Vdr | Alliance of Genome Resources | ||||
| atopic dermatitis 2 | FLG* | ||||||
| autosomal dominant dystrophic epidermolysis bullosa | COL7A1* | Col7a1 | Alliance of Genome Resources | ||||
| bullous pemphigoid | IL2* | Il2 | Alliance of Genome Resources | ||||
| cicatricial pemphigoid | HLA-DRB1*, HLA-DRB3, HLA-DRB4, HLA-DRB5 | H2-Eb1, H2-Eb2 | Alliance of Genome Resources | ||||
| cicatricial pemphigoid | HLA-DQB1*, HLA-DQB2 | H2-Ab1 | Alliance of Genome Resources | ||||
| contact dermatitis | CD46* | Cd46 | Alliance of Genome Resources | ||||
| contact dermatitis | XRCC1* | Xrcc1 | Alliance of Genome Resources | ||||
| dermatitis | IL13* | Il13 | Alliance of Genome Resources | ||||
| dermatitis | ADRB2* | Adrb2 | Alliance of Genome Resources | ||||
| dermatitis | FGF2* | Fgf2 | Alliance of Genome Resources | ||||
| dermatitis | HLA-B*, HLA-A, HLA-C, HLA-E, HLA-F, HLA-G, HLA-H | H2-D1, H2-K1, H2-L, H2-M1, H2-M2, H2-M3, H2-M5, H2-M9, H2-M10.1, H2-M10.2, H2-M10.3, H2-M10.4, H2-M10.5, H2-M10.6, H2-M11, H2-Q1, H2-Q2, H2-Q4, H2-Q6, H2-Q7, H2-Q8, H2-Q10, H2-T3, H2-T10, H2-T22, H2-T23 | Alliance of Genome Resources | ||||
| dermatitis | TNF* | Tnf | Alliance of Genome Resources | ||||
| dermatitis | IKBKB* | Ikbkb | Alliance of Genome Resources | ||||
| dermatitis herpetiformis | ELN* | Eln | Alliance of Genome Resources | ||||
| dermatitis herpetiformis | TNF* | Tnf | Alliance of Genome Resources | ||||
| dermatitis herpetiformis | LTA* | Lta | Alliance of Genome Resources | ||||
| epidermolysis bullosa dystrophica | MMP1* | Mmp1a, Mmp1b | Alliance of Genome Resources | ||||
| epidermolysis bullosa dystrophica | COL7A1* | Col7a1 | Alliance of Genome Resources | ||||
| epidermolysis bullosa simplex | EXPH5* | Exph5 | Alliance of Genome Resources | ||||
| epidermolysis bullosa simplex | KLHL24* | Klhl24 | Alliance of Genome Resources | ||||
| epidermolysis bullosa simplex | KRT5* | Krt5 | Alliance of Genome Resources | ||||
| epidermolysis bullosa simplex | PLEC* | Plec | Alliance of Genome Resources | ||||
| epidermolysis bullosa simplex | CD151* | Cd151 | Alliance of Genome Resources | ||||
| epidermolysis bullosa simplex | DST* | Dst | Alliance of Genome Resources | ||||
| epidermolysis bullosa simplex with mottled pigmentation | KRT5* | Krt5 | Alliance of Genome Resources | ||||
| epidermolysis bullosa with congenital localized absence of skin and deformity of nails | COL7A1* | Col7a1 | Alliance of Genome Resources | ||||
| Hailey-Hailey disease | ATP2C1* | Atp2c1 | 1 "NOT" model | Alliance of Genome Resources | |||
| junctional epidermolysis bullosa | LAMC2* | Lamc2 | 3 models | Alliance of Genome Resources | |||
| junctional epidermolysis bullosa | LAMB3* | Lamb3 | Alliance of Genome Resources | ||||
| junctional epidermolysis bullosa | ITGA3* | Itga3 | Alliance of Genome Resources | ||||
| junctional epidermolysis bullosa | ITGA6* | Itga6 | Alliance of Genome Resources | ||||
| junctional epidermolysis bullosa | ITGB4* | Itgb4 | Alliance of Genome Resources | ||||
| junctional epidermolysis bullosa with pyloric atresia | ITGA6* | Itga6 | Alliance of Genome Resources | ||||
| occupational dermatitis | NAT1*, NAT2* | Nat1, Nat2, Nat3 | Alliance of Genome Resources | ||||
| pemphigus | HLA-DRB1*, HLA-DRB3, HLA-DRB4, HLA-DRB5 | H2-Eb1, H2-Eb2 | Alliance of Genome Resources | ||||
| pemphigus | IL2* | Il2 | Alliance of Genome Resources | ||||
| pemphigus | CD40* | Cd40 | Alliance of Genome Resources | ||||
| pemphigus | CD36* | Cd36 | Alliance of Genome Resources | ||||
| pemphigus | CAST* | Cast | Alliance of Genome Resources | ||||
| pemphigus | HLA-DQB1*, HLA-DQB2 | H2-Ab1 | Alliance of Genome Resources | ||||
| pemphigus | HLA-DQA1*, HLA-DQA2 | H2-Aa | Alliance of Genome Resources | ||||
| pemphigus vulgaris | HLA-DQB1*, HLA-DQB2 | H2-Ab1 | Alliance of Genome Resources | ||||
| photosensitivity disease | BRD2* | Brd2 | Alliance of Genome Resources | ||||
| pretibial dystrophic epidermolysis bullosa | COL7A1* | Col7a1 | Alliance of Genome Resources | ||||
| pustulosis of palm and sole | LTA* | Lta | Alliance of Genome Resources | ||||
| pustulosis of palm and sole | TNF* | Tnf | Alliance of Genome Resources | ||||
| seborrheic dermatitis | TLR2* | Tlr2 | Alliance of Genome Resources | ||||
| transient bullous dermolysis of the newborn | COL7A1* | Col7a1 | Alliance of Genome Resources | ||||
| vesiculobullous skin disease | FERMT1* | Fermt1 | Alliance of Genome Resources | ||||
Excel File
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Transgenes and other genome features developed in mice to model this disease.
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| Disease Term | Transgenes and Other Genome Features | Mouse Models | |
| atopic dermatitis | Tg(KRT14-VP16/NR1I2)13Sdub | 1 model | |
| atopic dermatitis | Tg(APOC1)1Lmh | 1 model | |
| atopic dermatitis | Tg(CD2-Stat6*V625A*T626A)78Mhk | 1 model | |
| atopic dermatitis | Tg(KRT14-CASP1)1Miz | 1 model | |
| atopic dermatitis | Tg(KRT14-Il4)#Lsch | 1 model | |
| atopic dermatitis | Tg(KRT14-Il18)#Knak | 1 model | |
| atopic dermatitis | Tg(SV40-KLK7)1010Teg | 1 model | |
| atopic dermatitis | Tg(tetO-Il13)1Tazh | 1 model | |
| atopic dermatitis | Tg(tetO/CMV-Tslp)#Sfz | 1 model | |
| dermatitis | Tg(KRT5-IKBKB)2Armz | 1 model | |
| dermatitis | Tg(KRT5-IKBKB)1Armz | 1 model | |