Excel File Text File *Disease is associated/modeled with this Gene or a homolog. More...
      Disease Term Human Homologs Mouse Homologs Mouse Models Homology Source
     intrahepatic cholangiocarcinoma KRAS* Kras* 4 models Alliance of Genome Resources
papillary thyroid carcinoma BRAF* Braf* 2 models Alliance of Genome Resources
     follicular thyroid carcinoma THRB Thrb* 2 models Alliance of Genome Resources
follicular thyroid carcinoma PTEN Pten* 3 models Alliance of Genome Resources
follicular thyroid carcinoma PRKAR1A Prkar1a* 2 models Alliance of Genome Resources
     adenocarcinoma STRAP* Strap   Alliance of Genome Resources
adenocarcinoma APC* Apc   Alliance of Genome Resources
adenocarcinoma HMOX1* Hmox1   Alliance of Genome Resources
adenocarcinoma NAT1*, NAT2 Nat1, Nat2, Nat3   Alliance of Genome Resources
Barrett's adenocarcinoma GPX3* Gpx3   Alliance of Genome Resources
Barrett's adenocarcinoma GPX7* Gpx7   Alliance of Genome Resources
breast adenocarcinoma BRCA1* Brca1   Alliance of Genome Resources
breast adenocarcinoma CCNE1* Ccne1   Alliance of Genome Resources
breast adenocarcinoma KSR1* Ksr1   Alliance of Genome Resources
breast adenocarcinoma TNF* Tnf   Alliance of Genome Resources
bronchiolo-alveolar adenocarcinoma ALX4* Alx4   Alliance of Genome Resources
bronchiolo-alveolar adenocarcinoma EGFR* Egfr   Alliance of Genome Resources
bronchiolo-alveolar adenocarcinoma GSTP1* Gstp1, Gstp2, Gstp3, Gstp-ps   Alliance of Genome Resources
cervical mucinous adenocarcinoma STK11* Stk11   Alliance of Genome Resources
cholangiocarcinoma WDHD1* Wdhd1   Alliance of Genome Resources
cholangiocarcinoma ABCC2* Abcc2   Alliance of Genome Resources
cholangiocarcinoma APC* Apc   Alliance of Genome Resources
cholangiocarcinoma ASPH* Asph   Alliance of Genome Resources
cholangiocarcinoma BRAF* Braf   Alliance of Genome Resources
cholangiocarcinoma CYCS* Cycs   Alliance of Genome Resources
cholangiocarcinoma EZH2* Ezh2   Alliance of Genome Resources
cholangiocarcinoma GNAS* Gnas   Alliance of Genome Resources
cholangiocarcinoma FASLG* Fasl   Alliance of Genome Resources
cholangiocarcinoma GSTM1*, GSTM5 Gstm1, Gstm2, Gstm3, Gstm6   Alliance of Genome Resources
cholangiocarcinoma GSTP1* Gstp1, Gstp2, Gstp3, Gstp-ps   Alliance of Genome Resources
cholangiocarcinoma MGMT* Mgmt   Alliance of Genome Resources
cholangiocarcinoma MIR494* Mir494   Alliance of Genome Resources
cholangiocarcinoma MTHFR* Mthfr   Alliance of Genome Resources
cholangiocarcinoma NAT2*, NAT1 Nat1, Nat2, Nat3   Alliance of Genome Resources
cholangiocarcinoma OGG1* Ogg1   Alliance of Genome Resources
cholangiocarcinoma PPIA* Ppia   Alliance of Genome Resources
cholangiocarcinoma PREX2* Prex2   Alliance of Genome Resources
cholangiocarcinoma RNF43* Rnf43   Alliance of Genome Resources
cholangiocarcinoma SLC7A5* Slc7a5   Alliance of Genome Resources
cholangiocarcinoma THBS1* Thbs1   Alliance of Genome Resources
cholangiocarcinoma ALB* Alb   Alliance of Genome Resources
colon adenocarcinoma STAT6* Stat6   Alliance of Genome Resources
colon adenocarcinoma UBR5* Ubr5   Alliance of Genome Resources
colon adenocarcinoma ABHD5* Abhd5   Alliance of Genome Resources
colon adenocarcinoma BAX* Bax   Alliance of Genome Resources
colon adenocarcinoma CHD4* Chd4   Alliance of Genome Resources
colon adenocarcinoma CSF1R* Csf1r   Alliance of Genome Resources
colon adenocarcinoma GATA1* Gata1   Alliance of Genome Resources
colon adenocarcinoma JAK2* Jak2   Alliance of Genome Resources
colon adenocarcinoma KDM6A* Kdm6a   Alliance of Genome Resources
colon adenocarcinoma LOX* Lox   Alliance of Genome Resources
colon adenocarcinoma MAP2K7* Map2k7   Alliance of Genome Resources
colon adenocarcinoma MAPK1* Mapk1   Alliance of Genome Resources
colon adenocarcinoma MAPK3* Mapk3   Alliance of Genome Resources
colon adenocarcinoma MIR155* Mir155   Alliance of Genome Resources
colon adenocarcinoma MYD88* Myd88   Alliance of Genome Resources
colon adenocarcinoma PIK3CA* Pik3ca   Alliance of Genome Resources
colon adenocarcinoma PIK3R3* Pik3r3   Alliance of Genome Resources
colon adenocarcinoma RAC1* Rac1   Alliance of Genome Resources
colon adenocarcinoma RNASET2* Rnaset2a, Rnaset2b   Alliance of Genome Resources
colon adenocarcinoma SMC2* Smc2   Alliance of Genome Resources
colon adenocarcinoma SRC* Src   Alliance of Genome Resources
colon adenocarcinoma STAT1* Stat1   Alliance of Genome Resources
colon adenocarcinoma STAT3* Stat3   Alliance of Genome Resources
colon adenocarcinoma STAT5A* Stat5a   Alliance of Genome Resources
colon adenocarcinoma STAT5B* Stat5b   Alliance of Genome Resources
colon adenocarcinoma TGFB1* Tgfb1   Alliance of Genome Resources
colorectal adenocarcinoma RSPH1* Rsph1   Alliance of Genome Resources
colorectal adenocarcinoma TPRX1*  
colorectal adenocarcinoma TPST1* Tpst1   Alliance of Genome Resources
colorectal adenocarcinoma UTP23* Utp23   Alliance of Genome Resources
colorectal adenocarcinoma XRCC1* Xrcc1   Alliance of Genome Resources
colorectal adenocarcinoma BORCS5* Borcs5   Alliance of Genome Resources
colorectal adenocarcinoma BRAF* Braf   Alliance of Genome Resources
colorectal adenocarcinoma CCDC17* Ccdc17   Alliance of Genome Resources
colorectal adenocarcinoma CD44* Cd44   Alliance of Genome Resources
colorectal adenocarcinoma CYP4F8*, CYP4F2, CYP4F3, CYP4F11, CYP4F12 Cyp4f13, Cyp4f14, Cyp4f15, Cyp4f18, Cyp4f40   Alliance of Genome Resources
colorectal adenocarcinoma CYP24A1* Cyp24a1   Alliance of Genome Resources
colorectal adenocarcinoma DNMT3B* Dnmt3b   Alliance of Genome Resources
colorectal adenocarcinoma DOK3* Dok3   Alliance of Genome Resources
colorectal adenocarcinoma EZH2* Ezh2   Alliance of Genome Resources
colorectal adenocarcinoma FAM151A* Fam151a   Alliance of Genome Resources
colorectal adenocarcinoma FGFR2* Fgfr2   Alliance of Genome Resources
colorectal adenocarcinoma FLT3* Flt3   Alliance of Genome Resources
colorectal adenocarcinoma GATA6* Gata6   Alliance of Genome Resources
colorectal adenocarcinoma GJB3* Gjb3   Alliance of Genome Resources
colorectal adenocarcinoma GPX4* Gpx4   Alliance of Genome Resources
colorectal adenocarcinoma GSTM1*, GSTM5 Gstm1, Gstm2, Gstm3, Gstm6   Alliance of Genome Resources
colorectal adenocarcinoma GSTT1* Gstt1   Alliance of Genome Resources
colorectal adenocarcinoma IL16* Il16   Alliance of Genome Resources
colorectal adenocarcinoma KCNH1* Kcnh1   Alliance of Genome Resources
colorectal adenocarcinoma KDR* Kdr   Alliance of Genome Resources
colorectal adenocarcinoma KMT2B* Kmt2b   Alliance of Genome Resources
colorectal adenocarcinoma ABCB1* Abcb1a, Abcb1b   Alliance of Genome Resources
colorectal adenocarcinoma MAPK1* Mapk1   Alliance of Genome Resources
colorectal adenocarcinoma MAPK3* Mapk3   Alliance of Genome Resources
colorectal adenocarcinoma NOD2* Nod2   Alliance of Genome Resources
colorectal adenocarcinoma PCSK4* Pcsk4   Alliance of Genome Resources
colorectal adenocarcinoma RAB24* Rab24   Alliance of Genome Resources
colorectal adenocarcinoma RGS5* Rgs5   Alliance of Genome Resources
colorectal adenocarcinoma RNASET2* Rnaset2a, Rnaset2b   Alliance of Genome Resources
colorectal adenocarcinoma STAT5B* Stat5b   Alliance of Genome Resources
endometrial adenocarcinoma MAPK3* Mapk3   Alliance of Genome Resources
endometrial adenocarcinoma TSG101* Tsg101   Alliance of Genome Resources
endometrial adenocarcinoma TP53* Trp53   Alliance of Genome Resources
endometrial adenocarcinoma AXIN2* Axin2   Alliance of Genome Resources
endometrial adenocarcinoma ARID1A* Arid1a   Alliance of Genome Resources
endometrial adenocarcinoma MAPK1* Mapk1   Alliance of Genome Resources
endometrial adenocarcinoma PIK3R1* Pik3r1   Alliance of Genome Resources
esophagus adenocarcinoma TNFRSF10A*, TNFRSF10B, TNFRSF10C, TNFRSF10D Tnfrsf10b   Alliance of Genome Resources
esophagus adenocarcinoma VDR* Vdr   Alliance of Genome Resources
esophagus adenocarcinoma SLC22A18* Slc22a18   Alliance of Genome Resources
esophagus adenocarcinoma BIRC3* Birc3   Alliance of Genome Resources
esophagus adenocarcinoma CYP19A1* Cyp19a1   Alliance of Genome Resources
esophagus adenocarcinoma ERCC1* Ercc1   Alliance of Genome Resources
esophagus adenocarcinoma NOS3* Nos3   Alliance of Genome Resources
esophagus adenocarcinoma MMP14* Mmp14   Alliance of Genome Resources
esophagus adenocarcinoma MMP12* Mmp12   Alliance of Genome Resources
esophagus adenocarcinoma MMP3* Mmp3   Alliance of Genome Resources
esophagus adenocarcinoma GPX3* Gpx3   Alliance of Genome Resources
esophagus adenocarcinoma GHRL* Ghrl   Alliance of Genome Resources
esophagus adenocarcinoma FOXP1* Foxp1   Alliance of Genome Resources
esophagus adenocarcinoma ABL1* Abl1   Alliance of Genome Resources
esophagus adenocarcinoma BCL2* Bcl2   Alliance of Genome Resources
esophagus adenocarcinoma CASP8* Casp8   Alliance of Genome Resources
esophagus adenocarcinoma MMP1* Mmp1a, Mmp1b   Alliance of Genome Resources
esophagus adenocarcinoma KDR* Kdr   Alliance of Genome Resources
esophagus adenocarcinoma GSTT1* Gstt1   Alliance of Genome Resources
esophagus adenocarcinoma GSTM1*, GSTM5 Gstm1, Gstm2, Gstm3, Gstm6   Alliance of Genome Resources
esophagus adenocarcinoma GRB7* Grb7   Alliance of Genome Resources
extrahepatic bile duct adenocarcinoma PBRM1* Pbrm1   Alliance of Genome Resources
extrahepatic bile duct adenocarcinoma BAP1* Bap1   Alliance of Genome Resources
gallbladder adenocarcinoma DDR2* Ddr2   Alliance of Genome Resources
gallbladder adenocarcinoma ACE* Ace   Alliance of Genome Resources
gallbladder adenocarcinoma IFITM1* Ifitm1   Alliance of Genome Resources
gastric adenocarcinoma ABCA13* Abca13   Alliance of Genome Resources
gastric adenocarcinoma XPO1* Xpo1   Alliance of Genome Resources
gastric adenocarcinoma UBR5* Ubr5   Alliance of Genome Resources
gastric adenocarcinoma TP53* Trp53   Alliance of Genome Resources
gastric adenocarcinoma RTEL1* Rtel1   Alliance of Genome Resources
gastric adenocarcinoma RNF43* Rnf43   Alliance of Genome Resources
gastric adenocarcinoma PLCE1* Plce1   Alliance of Genome Resources
gastric adenocarcinoma KMT2D* Kmt2d   Alliance of Genome Resources
gastric adenocarcinoma IRF1* Irf1   Alliance of Genome Resources
gastric adenocarcinoma HLA-DQA1*, HLA-DQA2 H2-Aa   Alliance of Genome Resources
gastric adenocarcinoma CD44* Cd44   Alliance of Genome Resources
gastric cardia adenocarcinoma XRCC1* Xrcc1   Alliance of Genome Resources
intrahepatic cholangiocarcinoma IDH2* Idh2   Alliance of Genome Resources
intrahepatic cholangiocarcinoma LRP1B* Lrp1b   Alliance of Genome Resources
intrahepatic cholangiocarcinoma BRAF* Braf   Alliance of Genome Resources
Klatskin's tumor PREX2* Prex2   Alliance of Genome Resources
Klatskin's tumor KRAS* Kras   Alliance of Genome Resources
Klatskin's tumor KMT2C* Kmt2c   Alliance of Genome Resources
Klatskin's tumor GATA6* Gata6   Alliance of Genome Resources
Klatskin's tumor ARID1A* Arid1a   Alliance of Genome Resources
lung adenocarcinoma FGFR4* Fgfr4   Alliance of Genome Resources
lung adenocarcinoma ADAM28* Adam28   Alliance of Genome Resources
lung adenocarcinoma ALX4* Alx4   Alliance of Genome Resources
lung adenocarcinoma AXIN2* Axin2   Alliance of Genome Resources
lung adenocarcinoma MYC* Bmyc, Myc   Alliance of Genome Resources
lung adenocarcinoma CALR* Calr   Alliance of Genome Resources
lung adenocarcinoma CCND1* Ccnd1   Alliance of Genome Resources
lung adenocarcinoma CCND2* Ccnd2   Alliance of Genome Resources
lung adenocarcinoma CHD4* Chd4   Alliance of Genome Resources
lung adenocarcinoma CHRNA3* Chrna3   Alliance of Genome Resources
lung adenocarcinoma CHRNA5* Chrna5   Alliance of Genome Resources
lung adenocarcinoma CHRNB4* Chrnb4   Alliance of Genome Resources
lung adenocarcinoma CLPTM1L* Clptm1l   Alliance of Genome Resources
lung adenocarcinoma CYP24A1* Cyp24a1   Alliance of Genome Resources
lung adenocarcinoma DNMT3B* Dnmt3b   Alliance of Genome Resources
lung adenocarcinoma EGF* Egf   Alliance of Genome Resources
lung adenocarcinoma EGFR* Egfr   Alliance of Genome Resources
lung adenocarcinoma ERBB2* Erbb2   Alliance of Genome Resources
lung adenocarcinoma ERBB3* Erbb3   Alliance of Genome Resources
lung adenocarcinoma ERBB4* Erbb4   Alliance of Genome Resources
lung adenocarcinoma ESCO2* Esco2   Alliance of Genome Resources
lung adenocarcinoma FES* Fes   Alliance of Genome Resources
lung adenocarcinoma HTRA1* Htra1   Alliance of Genome Resources
lung adenocarcinoma IQSEC1* Iqsec1   Alliance of Genome Resources
lung adenocarcinoma JAK2* Jak2   Alliance of Genome Resources
lung adenocarcinoma KMT2C* Kmt2c   Alliance of Genome Resources
lung adenocarcinoma KRAS* Kras   Alliance of Genome Resources
lung adenocarcinoma LECT2* Lect2   Alliance of Genome Resources
lung adenocarcinoma LRP1B* Lrp1b   Alliance of Genome Resources
lung adenocarcinoma MAP2K7* Map2k7   Alliance of Genome Resources
lung adenocarcinoma MAP4K4* Map4k4   Alliance of Genome Resources
lung adenocarcinoma MCL1* Mcl1   Alliance of Genome Resources
lung adenocarcinoma MIR127* Mir127   Alliance of Genome Resources
lung adenocarcinoma MIR432* Mir432   Alliance of Genome Resources
lung adenocarcinoma MSH2* Msh2   Alliance of Genome Resources
lung adenocarcinoma PRDM1* Prdm1   Alliance of Genome Resources
lung adenocarcinoma PTCH1* Ptch1   Alliance of Genome Resources
lung adenocarcinoma PTPN13* Ptpn13   Alliance of Genome Resources
lung adenocarcinoma PTPRJ* Ptprj   Alliance of Genome Resources
lung adenocarcinoma RARB* Rarb   Alliance of Genome Resources
lung adenocarcinoma RBM10* Rbm10   Alliance of Genome Resources
lung adenocarcinoma RNF43* Rnf43   Alliance of Genome Resources
lung adenocarcinoma SETD2* Setd2   Alliance of Genome Resources
lung adenocarcinoma SPOP* Spop   Alliance of Genome Resources
lung adenocarcinoma SULT1A1*, SULT1A2, SULT1A3, SULT1A4 Sult1a1   Alliance of Genome Resources
lung adenocarcinoma TERT* Tert   Alliance of Genome Resources
lung adenocarcinoma UBR5* Ubr5   Alliance of Genome Resources
lung adenocarcinoma XRCC1* Xrcc1   Alliance of Genome Resources
lung adenocarcinoma ZFHX3* Zfhx3   Alliance of Genome Resources
mammary Paget's disease ERBB2* Erbb2   Alliance of Genome Resources
mucinous adenocarcinoma MUC1* Muc1   Alliance of Genome Resources
oncocytic carcinoma of the thyroid NDUFA13* Ndufa13   Alliance of Genome Resources
ovary serous adenocarcinoma TP53* Trp53   Alliance of Genome Resources
pancreatic acinar cell adenocarcinoma BRAF* Braf   Alliance of Genome Resources
pancreatic adenocarcinoma GSTT1* Gstt1   Alliance of Genome Resources
pancreatic adenocarcinoma E2F1* E2f1   Alliance of Genome Resources
pancreatic adenocarcinoma CXCR4* Cxcr4   Alliance of Genome Resources
pancreatic adenocarcinoma CDKN2A* Cdkn2a   Alliance of Genome Resources
pancreatic adenocarcinoma CDK6* Cdk6   Alliance of Genome Resources
pancreatic adenocarcinoma CDK4* Cdk4   Alliance of Genome Resources
pancreatic adenocarcinoma SMAD7* Smad7   Alliance of Genome Resources
pancreatic adenocarcinoma RALBP1* Ralbp1   Alliance of Genome Resources
pancreatic adenocarcinoma RALB* Ralb   Alliance of Genome Resources
pancreatic adenocarcinoma RAC1* Rac1   Alliance of Genome Resources
pancreatic adenocarcinoma RAF1* Raf1   Alliance of Genome Resources
pancreatic adenocarcinoma MAPK10* Mapk10   Alliance of Genome Resources
pancreatic adenocarcinoma MAPK9* Mapk9   Alliance of Genome Resources
pancreatic adenocarcinoma MAP2K1* Map2k1   Alliance of Genome Resources
pancreatic adenocarcinoma JAK1* Jak1   Alliance of Genome Resources
pancreatic ductal adenocarcinoma TGFBR1* Tgfbr1   Alliance of Genome Resources
pancreatic ductal adenocarcinoma PIK3R2* Pik3r2   Alliance of Genome Resources
pancreatic ductal adenocarcinoma MIR494* Mir494   Alliance of Genome Resources
pancreatic ductal adenocarcinoma GOT1* Got1   Alliance of Genome Resources
pancreatic ductal adenocarcinoma E2F1* E2f1   Alliance of Genome Resources
pancreatic ductal adenocarcinoma CCND1* Ccnd1   Alliance of Genome Resources
pancreatic ductal adenocarcinoma CALR* Calr   Alliance of Genome Resources
papillary thyroid carcinoma XRCC1* Xrcc1   Alliance of Genome Resources
papillary thyroid carcinoma WDR3* Wdr3   Alliance of Genome Resources
papillary thyroid carcinoma TP53* Trp53   Alliance of Genome Resources
papillary thyroid carcinoma SRGAP1* Srgap1   Alliance of Genome Resources
papillary thyroid carcinoma NRAS* Nras   Alliance of Genome Resources
papillary thyroid carcinoma NKX2-1* Nkx2-1   Alliance of Genome Resources
papillary thyroid carcinoma MINPP1* Minpp1   Alliance of Genome Resources
papillary thyroid carcinoma KMT2D* Kmt2d   Alliance of Genome Resources
papillary thyroid carcinoma HRAS* Hras   Alliance of Genome Resources
papillary thyroid carcinoma HABP2* Habp2   Alliance of Genome Resources
papillary thyroid carcinoma FOXE1* Foxe1   Alliance of Genome Resources
papillary thyroid carcinoma ATM* Atm   Alliance of Genome Resources
prostate adenocarcinoma MYC* Bmyc, Myc   Alliance of Genome Resources
prostate adenocarcinoma ADIPOQ* Adipoq   Alliance of Genome Resources
prostate adenocarcinoma STAT1* Stat1   Alliance of Genome Resources
prostate adenocarcinoma BIN1* Bin1   Alliance of Genome Resources
prostate adenocarcinoma AKT3* Akt3   Alliance of Genome Resources
prostate adenocarcinoma AKT2* Akt2   Alliance of Genome Resources
prostate adenocarcinoma AKT1* Akt1   Alliance of Genome Resources
prostate adenocarcinoma ADIPOR1* Adipor1   Alliance of Genome Resources
prostate adenocarcinoma BRAF* Braf   Alliance of Genome Resources
prostate adenocarcinoma CAMK2N1* Camk2n1   Alliance of Genome Resources
prostate adenocarcinoma CD9* Cd9   Alliance of Genome Resources
prostate adenocarcinoma FGF2* Fgf2   Alliance of Genome Resources
prostate adenocarcinoma GRB2* Grb2   Alliance of Genome Resources
prostate adenocarcinoma IGF1R* Igf1r   Alliance of Genome Resources
prostate adenocarcinoma IKBKB* Ikbkb   Alliance of Genome Resources
prostate adenocarcinoma INSR* Insr   Alliance of Genome Resources
prostate adenocarcinoma MAPK1* Mapk1   Alliance of Genome Resources
prostate adenocarcinoma NCOA2* Ncoa2   Alliance of Genome Resources
prostate adenocarcinoma PIK3CB* Pik3cb   Alliance of Genome Resources
prostate adenocarcinoma RAF1* Raf1   Alliance of Genome Resources
rectum adenocarcinoma STAT3* Stat3   Alliance of Genome Resources
rectum adenocarcinoma STAT6* Stat6   Alliance of Genome Resources
rectum adenocarcinoma STAT4* Stat4   Alliance of Genome Resources
small intestine adenocarcinoma GSTM1*, GSTM5 Gstm1, Gstm2, Gstm3, Gstm6   Alliance of Genome Resources
small intestine adenocarcinoma MAP2K2* Map2k2   Alliance of Genome Resources
small intestine adenocarcinoma MAP2K1* Map2k1   Alliance of Genome Resources

 
Transgenes and other genome features developed in mice to model this disease.
     Disease Term Transgenes and Other Genome Features Mouse Models
  follicular thyroid carcinoma Tg(TG-NRAS*Q61K)#Msnt 1 model
  lung adenocarcinoma Tg(SFTPC-env)1Yhch 1 model
  lung adenocarcinoma Tg(tetO-Kras2)12Hev 1 model
  papillary thyroid carcinoma Tg(TG-TPR/NTRK1)5215Rstn 1 model
  papillary thyroid carcinoma Tg(tetO-BRAF*V600E)26Jaf 1 model
  papillary thyroid carcinoma Tg(TG-BRAF*V600E)2Jaf 1 model
  papillary thyroid carcinoma Tg(TG-RET/CCDC6)42Cled 1 model
  papillary thyroid carcinoma Tg(TG-RET/NCOA4)3209Rstn 1 model
  prostate adenocarcinoma Tg(Pbsn-Tag)12T10Rjm 1 model