Disease Term | Human Homologs | Mouse Homologs | Mouse Models | Homology Source | |||
glioblastoma | TP53 | Trp53* | 2 models | Alliance of Genome Resources | |||
malignant astrocytoma | HRAS | Hras* | 1 model | Alliance of Genome Resources | |||
astroblastoma | PIK3R1* | Pik3r1 | Alliance of Genome Resources | ||||
childhood astrocytic tumor | RTEL1* | Rtel1 | Alliance of Genome Resources | ||||
glioblastoma | XRCC1* | Xrcc1 | Alliance of Genome Resources | ||||
glioblastoma | RPL5* | Rpl5 | Alliance of Genome Resources | ||||
glioblastoma | RB1* | Rb1 | Alliance of Genome Resources | ||||
glioblastoma | PTPRB* | Ptprb | Alliance of Genome Resources | ||||
glioblastoma | PIK3CB* | Pik3cb | Alliance of Genome Resources | ||||
glioblastoma | PGF* | Pgf | Alliance of Genome Resources | ||||
glioblastoma | PDGFRB* | Pdgfrb | Alliance of Genome Resources | ||||
glioblastoma | ADGRB1* | Adgrb1 | Alliance of Genome Resources | ||||
glioblastoma | AKT3* | Akt3 | Alliance of Genome Resources | ||||
glioblastoma | ARRB2* | Arrb2 | Alliance of Genome Resources | ||||
glioblastoma | CDK4* | Cdk4 | Alliance of Genome Resources | ||||
glioblastoma | CDKN2A* | Cdkn2a | Alliance of Genome Resources | ||||
glioblastoma | DMBT1* | Dmbt1 | Alliance of Genome Resources | ||||
glioblastoma | EGF* | Egf | Alliance of Genome Resources | ||||
glioblastoma | EZH2* | Ezh2 | Alliance of Genome Resources | ||||
glioblastoma | FLT3LG* | Flt3l | Alliance of Genome Resources | ||||
glioblastoma | FXN* | Fxn | Alliance of Genome Resources | ||||
glioblastoma | IDH1* | Idh1 | Alliance of Genome Resources | ||||
glioblastoma | KDR* | Kdr | Alliance of Genome Resources | ||||
glioblastoma | LZTR1* | Lztr1 | Alliance of Genome Resources | ||||
glioblastoma | MAP1LC3A* | Map1lc3a | Alliance of Genome Resources | ||||
glioblastoma | MDM2* | Mdm2 | Alliance of Genome Resources | ||||
glioblastoma | MGMT* | Mgmt | Alliance of Genome Resources | ||||
glioblastoma | MMP9* | Mmp9 | Alliance of Genome Resources | ||||
glioblastoma | NRAS* | Nras | Alliance of Genome Resources | ||||
glioblastoma | NFKBIA* | Nfkbia | Alliance of Genome Resources | ||||
glioblastoma | PDGFB* | Pdgfb | Alliance of Genome Resources | ||||
malignant astrocytoma | BRAF* | Braf | Alliance of Genome Resources | ||||
malignant astrocytoma | CADM2* | Cadm2 | Alliance of Genome Resources | ||||
malignant astrocytoma | GSTM1*, GSTM5 | Gstm1, Gstm2, Gstm3, Gstm6 | Alliance of Genome Resources | ||||
malignant astrocytoma | GSTP1* | Gstp1, Gstp2, Gstp3, Gstp-ps | Alliance of Genome Resources | ||||
malignant astrocytoma | KRAS* | Kras | Alliance of Genome Resources |
Transgenes and other genome features developed in mice to model this disease.
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Disease Term | Transgenes and Other Genome Features | Mouse Models | |
malignant astrocytoma | Tg(GFAP-Hras1)2Agu | 1 model | |
malignant astrocytoma | Tg(GFAP-SRC)1Aag | 1 model | |
malignant astrocytoma | Tg(GFAP-SRC)2Aag | 1 model | |
malignant astrocytoma | Tg(GFAP-TAg121)1Tvd | 2 models |