| Disease Term | Human Homologs | Mouse Homologs | Mouse Models | Homology Source | |||
 | glioblastoma | TP53 | Trp53* | 2 models | Alliance of Genome Resources | ||
| high grade glioma | HRAS | Hras* | 1 model | Alliance of Genome Resources | |||
| malignant astrocytoma | HRAS | Hras* | 1 model | Alliance of Genome Resources | |||
 | astroblastoma | PIK3R1* | Pik3r1 | Alliance of Genome Resources | |||
| childhood astrocytic tumor | RTEL1* | Rtel1 | Alliance of Genome Resources | ||||
| chordoid glioma | PRKCA* | Prkca | Alliance of Genome Resources | ||||
| glioblastoma | NRAS* | Nras | Alliance of Genome Resources | ||||
| glioblastoma | PDGFRB* | Pdgfrb | Alliance of Genome Resources | ||||
| glioblastoma | NFKBIA* | Nfkbia | Alliance of Genome Resources | ||||
| glioblastoma | PDGFB* | Pdgfb | Alliance of Genome Resources | ||||
| glioblastoma | XRCC1* | Xrcc1 | Alliance of Genome Resources | ||||
| glioblastoma | RPL5* | Rpl5 | Alliance of Genome Resources | ||||
| glioblastoma | RB1* | Rb1 | Alliance of Genome Resources | ||||
| glioblastoma | PTPRB* | Ptprb | Alliance of Genome Resources | ||||
| glioblastoma | PIK3CB* | Pik3cb | Alliance of Genome Resources | ||||
| glioblastoma | PGF* | Pgf | Alliance of Genome Resources | ||||
| glioblastoma | ADGRB1* | Adgrb1 | Alliance of Genome Resources | ||||
| glioblastoma | AKT3* | Akt3 | Alliance of Genome Resources | ||||
| glioblastoma | ARRB2* | Arrb2 | Alliance of Genome Resources | ||||
| glioblastoma | CDK4* | Cdk4 | Alliance of Genome Resources | ||||
| glioblastoma | CDKN2A* | Cdkn2a | Alliance of Genome Resources | ||||
| glioblastoma | DMBT1* | Dmbt1 | Alliance of Genome Resources | ||||
| glioblastoma | EGF* | Egf | Alliance of Genome Resources | ||||
| glioblastoma | EZH2* | Ezh2 | Alliance of Genome Resources | ||||
| glioblastoma | FLT3LG* | Flt3l | Alliance of Genome Resources | ||||
| glioblastoma | FXN* | Fxn | Alliance of Genome Resources | ||||
| glioblastoma | IDH1* | Idh1 | Alliance of Genome Resources | ||||
| glioblastoma | KDR* | Kdr | Alliance of Genome Resources | ||||
| glioblastoma | LZTR1* | Lztr1 | Alliance of Genome Resources | ||||
| glioblastoma | MAP1LC3A* | Map1lc3a | Alliance of Genome Resources | ||||
| glioblastoma | MDM2* | Mdm2 | Alliance of Genome Resources | ||||
| glioblastoma | MGMT* | Mgmt | Alliance of Genome Resources | ||||
| glioblastoma | MMP9* | Mmp9 | Alliance of Genome Resources | ||||
| high grade glioma | NF1* | Nf1 | Alliance of Genome Resources | ||||
| high grade glioma | GSTM1*, GSTM5 | Gstm1, Gstm2, Gstm3, Gstm6 | Alliance of Genome Resources | ||||
| high grade glioma | GSTM3* | Gstm5 | Alliance of Genome Resources | ||||
| high grade glioma | GSTP1* | Gstp1, Gstp2, Gstp3, Gstp-ps | Alliance of Genome Resources | ||||
| high grade glioma | IDH1* | Idh1 | Alliance of Genome Resources | ||||
| high grade glioma | IGF1R* | Igf1r | Alliance of Genome Resources | ||||
| high grade glioma | IL2* | Il2 | Alliance of Genome Resources | ||||
| high grade glioma | IL10* | Il10 | Alliance of Genome Resources | ||||
| high grade glioma | KDM5B* | Kdm5b | Alliance of Genome Resources | ||||
| high grade glioma | LIG4* | Lig4 | Alliance of Genome Resources | ||||
| high grade glioma | LTA* | Lta | Alliance of Genome Resources | ||||
| high grade glioma | MAP2K1* | Map2k1 | Alliance of Genome Resources | ||||
| high grade glioma | NADSYN1* | Nadsyn1 | Alliance of Genome Resources | ||||
| high grade glioma | PDGFA* | Pdgfa | Alliance of Genome Resources | ||||
| high grade glioma | PDGFB* | Pdgfb | Alliance of Genome Resources | ||||
| high grade glioma | PRKCA* | Prkca | Alliance of Genome Resources | ||||
| high grade glioma | PTEN* | Pten | 5 models | Alliance of Genome Resources | |||
| high grade glioma | SH3GL1* | Sh3gl1 | Alliance of Genome Resources | ||||
| high grade glioma | SLC44A1* | Slc44a1 | Alliance of Genome Resources | ||||
| high grade glioma | SOX6* | Sox6 | Alliance of Genome Resources | ||||
| high grade glioma | TNF* | Tnf | Alliance of Genome Resources | ||||
| high grade glioma | TP53* | Trp53 | 3 models | Alliance of Genome Resources | |||
| high grade glioma | XRCC1* | Xrcc1 | Alliance of Genome Resources | ||||
| high grade glioma | XRCC3* | Xrcc3 | Alliance of Genome Resources | ||||
| high grade glioma | ATRX* | Atrx | Alliance of Genome Resources | ||||
| high grade glioma | BRCA2* | Brca2 | Alliance of Genome Resources | ||||
| high grade glioma | CCDC26* | ||||||
| high grade glioma | CCN1* | Ccn1 | Alliance of Genome Resources | ||||
| high grade glioma | CCND1* | Ccnd1 | Alliance of Genome Resources | ||||
| high grade glioma | CDK6* | Cdk6 | Alliance of Genome Resources | ||||
| high grade glioma | CDKN1A* | Cdkn1a | Alliance of Genome Resources | ||||
| high grade glioma | CDKN2A* | Cdkn2a | 3 models | Alliance of Genome Resources | |||
| high grade glioma | CHAF1A* | Chaf1a | Alliance of Genome Resources | ||||
| high grade glioma | CYP2E1* | Cyp2e1 | Alliance of Genome Resources | ||||
| high grade glioma | DCN* | Dcn | Alliance of Genome Resources | ||||
| high grade glioma | EGF* | Egf | Alliance of Genome Resources | ||||
| high grade glioma | ENTPD2* | Entpd2 | Alliance of Genome Resources | ||||
| high grade glioma | EPO* | Epo | Alliance of Genome Resources | ||||
| high grade glioma | EPOR* | Epor | Alliance of Genome Resources | ||||
| high grade glioma | ERBB2* | Erbb2 | Alliance of Genome Resources | ||||
| high grade glioma | ERCC1* | Ercc1 | Alliance of Genome Resources | ||||
| high grade glioma | ERCC2* | Ercc2 | Alliance of Genome Resources | ||||
| high grade glioma | ERCC5* | Ercc5 | Alliance of Genome Resources | ||||
| high grade glioma | FLT3LG* | Flt3l | Alliance of Genome Resources | ||||
| malignant astrocytoma | BRAF* | Braf | Alliance of Genome Resources | ||||
| malignant astrocytoma | CADM2* | Cadm2 | Alliance of Genome Resources | ||||
| malignant astrocytoma | GSTM1*, GSTM5 | Gstm1, Gstm2, Gstm3, Gstm6 | Alliance of Genome Resources | ||||
| malignant astrocytoma | GSTP1* | Gstp1, Gstp2, Gstp3, Gstp-ps | Alliance of Genome Resources | ||||
| malignant astrocytoma | KRAS* | Kras | Alliance of Genome Resources | ||||
| mixed glioma | RTEL1* | Rtel1 | Alliance of Genome Resources | ||||
| oligodendroglioma | EGF* | Egf | Alliance of Genome Resources | ||||
| oligodendroglioma | MGMT* | Mgmt | Alliance of Genome Resources | ||||
| oligodendroglioma | RB1* | Rb1 | Alliance of Genome Resources | ||||
Excel File
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Transgenes and other genome features developed in mice to model this disease.
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| Disease Term | Transgenes and Other Genome Features | Mouse Models | |
| high grade glioma | Tg(GFAP-Hras1)2Agu | 1 model | |
| malignant astrocytoma | Tg(GFAP-SRC)2Aag | 1 model | |
| malignant astrocytoma | Tg(GFAP-TAg121)1Tvd | 2 models | |
| malignant astrocytoma | Tg(GFAP-Hras1)2Agu | 1 model | |
| malignant astrocytoma | Tg(GFAP-SRC)1Aag | 1 model | |
| oligodendroglioma | Tg(S100b-v-erbB)4496Waw | 4 models | |