| Disease Term | Human Homologs | Mouse Homologs | Mouse Models | Homology Source | |||
 | pulmonary emphysema | BLOC1S6 | Bloc1s6* | 1 model | Alliance of Genome Resources | ||
| pulmonary emphysema | FSTL1 | Fstl1* | 1 model | Alliance of Genome Resources | |||
| pulmonary emphysema | FUT8 | Fut8* | 1 model | Alliance of Genome Resources | |||
| pulmonary emphysema | ITGB6 | Itgb6* | 1 model | Alliance of Genome Resources | |||
| pulmonary emphysema | JUN | Jun* | 1 model | Alliance of Genome Resources | |||
| pulmonary emphysema | KL | Kl* | 1 model | Alliance of Genome Resources | |||
| pulmonary emphysema | MUS81 | Mus81* | 1 model | Alliance of Genome Resources | |||
| pulmonary emphysema | PTMA | Ptma* | 2 models | Alliance of Genome Resources | |||
| pulmonary emphysema | SMO | Smo* | 1 model | Alliance of Genome Resources | |||
| pulmonary emphysema | TLR4 | Tlr4* | 1 model | Alliance of Genome Resources | |||
 | chronic obstructive pulmonary disease | ELN* | Eln | Alliance of Genome Resources | |||
| chronic obstructive pulmonary disease | ACE* | Ace | Alliance of Genome Resources | ||||
| chronic obstructive pulmonary disease | ADAM33* | Adam33 | Alliance of Genome Resources | ||||
| chronic obstructive pulmonary disease | ADRB1* | Adrb1 | Alliance of Genome Resources | ||||
| chronic obstructive pulmonary disease | ADRB2* | Adrb2 | Alliance of Genome Resources | ||||
| chronic obstructive pulmonary disease | BDKRB2* | Bdkrb2 | Alliance of Genome Resources | ||||
| chronic obstructive pulmonary disease | CCL1* | Ccl1 | Alliance of Genome Resources | ||||
| chronic obstructive pulmonary disease | CD86* | Cd86 | Alliance of Genome Resources | ||||
| chronic obstructive pulmonary disease | CFTR* | Cftr | Alliance of Genome Resources | ||||
| chronic obstructive pulmonary disease | CHRM3* | Chrm3 | Alliance of Genome Resources | ||||
| chronic obstructive pulmonary disease | CHRNA3* | Chrna3 | Alliance of Genome Resources | ||||
| chronic obstructive pulmonary disease | CHRNA5* | Chrna5 | Alliance of Genome Resources | ||||
| chronic obstructive pulmonary disease | CHRNA7*, CHRFAM7A | Chrna7 | Alliance of Genome Resources | ||||
| chronic obstructive pulmonary disease | CLCA1* | Clca1 | Alliance of Genome Resources | ||||
| chronic obstructive pulmonary disease | CRHR1*, LINC02210-CRHR1 | Crhr1 | Alliance of Genome Resources | ||||
| chronic obstructive pulmonary disease | CTLA4* | Ctla4 | Alliance of Genome Resources | ||||
| chronic obstructive pulmonary disease | CYBA* | Cyba | Alliance of Genome Resources | ||||
| chronic obstructive pulmonary disease | CYP1A1* | Cyp1a1 | Alliance of Genome Resources | ||||
| chronic obstructive pulmonary disease | CYP1A2* | Cyp1a2 | Alliance of Genome Resources | ||||
| chronic obstructive pulmonary disease | CYP2E1* | Cyp2e1 | Alliance of Genome Resources | ||||
| chronic obstructive pulmonary disease | DEFB1* | Defb1, Defb37 | Alliance of Genome Resources | ||||
| chronic obstructive pulmonary disease | EDN1* | Edn1 | Alliance of Genome Resources | ||||
| chronic obstructive pulmonary disease | ABCC1* | Abcc1 | Alliance of Genome Resources | ||||
| chronic obstructive pulmonary disease | EPHX1* | Ephx1 | Alliance of Genome Resources | ||||
| chronic obstructive pulmonary disease | F2RL1* | F2rl1 | Alliance of Genome Resources | ||||
| chronic obstructive pulmonary disease | FAM13A* | Fam13a | Alliance of Genome Resources | ||||
| chronic obstructive pulmonary disease | GC* | Gc | Alliance of Genome Resources | ||||
| chronic obstructive pulmonary disease | GRIK5* | Grik5 | Alliance of Genome Resources | ||||
| chronic obstructive pulmonary disease | GRIN2B* | Grin2b | Alliance of Genome Resources | ||||
| chronic obstructive pulmonary disease | GSTM1*, GSTM5 | Gstm1, Gstm2, Gstm3, Gstm6 | Alliance of Genome Resources | ||||
| chronic obstructive pulmonary disease | GSTP1* | Gstp1, Gstp2, Gstp3, Gstp-ps | Alliance of Genome Resources | ||||
| chronic obstructive pulmonary disease | GSTT1* | Gstt1 | Alliance of Genome Resources | ||||
| chronic obstructive pulmonary disease | HHIP* | Hhip | Alliance of Genome Resources | ||||
| chronic obstructive pulmonary disease | HLA-DPB1* | ||||||
| chronic obstructive pulmonary disease | HMOX1* | Hmox1 | Alliance of Genome Resources | ||||
| chronic obstructive pulmonary disease | HTR2A* | Htr2a | Alliance of Genome Resources | ||||
| chronic obstructive pulmonary disease | IL1B* | Il1b | Alliance of Genome Resources | ||||
| chronic obstructive pulmonary disease | IL1RN* | Il1rn | Alliance of Genome Resources | ||||
| chronic obstructive pulmonary disease | IL12B* | Il12b | Alliance of Genome Resources | ||||
| chronic obstructive pulmonary disease | IL13* | Il13 | Alliance of Genome Resources | ||||
| chronic obstructive pulmonary disease | IL13RA1* | Il13ra1 | Alliance of Genome Resources | ||||
| chronic obstructive pulmonary disease | IL27* | Il27 | Alliance of Genome Resources | ||||
| chronic obstructive pulmonary disease | LEP* | Lep | Alliance of Genome Resources | ||||
| chronic obstructive pulmonary disease | LEPR* | Lepr | Alliance of Genome Resources | ||||
| chronic obstructive pulmonary disease | LRP1B* | Lrp1b | Alliance of Genome Resources | ||||
| chronic obstructive pulmonary disease | MBL2* | Mbl2 | Alliance of Genome Resources | ||||
| chronic obstructive pulmonary disease | MMP9* | Mmp9 | Alliance of Genome Resources | ||||
| chronic obstructive pulmonary disease | NAT2*, NAT1 | Nat1, Nat2, Nat3 | Alliance of Genome Resources | ||||
| chronic obstructive pulmonary disease | NOD2* | Nod2 | Alliance of Genome Resources | ||||
| chronic obstructive pulmonary disease | NQO1* | Nqo1 | Alliance of Genome Resources | ||||
| chronic obstructive pulmonary disease | NR3C1* | Nr3c1 | Alliance of Genome Resources | ||||
| chronic obstructive pulmonary disease | PTGS2* | Ptgs2 | Alliance of Genome Resources | ||||
| chronic obstructive pulmonary disease | RTEL1* | Rtel1 | Alliance of Genome Resources | ||||
| chronic obstructive pulmonary disease | SERPINA1* | Serpina1a, Serpina1b, Serpina1c, Serpina1d, Serpina1e | Alliance of Genome Resources | ||||
| chronic obstructive pulmonary disease | SERPINA3* | Serpina3a, Serpina3b, Serpina3c, Serpina3f, Serpina3g, Serpina3i, Serpina3j, Serpina3k, Serpina3m, Serpina3n | Alliance of Genome Resources | ||||
| chronic obstructive pulmonary disease | SFTPA1*, SFTPA2 | Sftpa1 | Alliance of Genome Resources | ||||
| chronic obstructive pulmonary disease | SFTPB* | Sftpb | Alliance of Genome Resources | ||||
| chronic obstructive pulmonary disease | SFTPC* | Sftpc | Alliance of Genome Resources | ||||
| chronic obstructive pulmonary disease | SFTPD* | Sftpd | Alliance of Genome Resources | ||||
| chronic obstructive pulmonary disease | SLC6A4* | Slc6a4 | Alliance of Genome Resources | ||||
| chronic obstructive pulmonary disease | SOD3* | Sod3 | Alliance of Genome Resources | ||||
| chronic obstructive pulmonary disease | TGFB1* | Tgfb1 | Alliance of Genome Resources | ||||
| chronic obstructive pulmonary disease | TLR4* | Tlr4 | Alliance of Genome Resources | ||||
| chronic obstructive pulmonary disease | TNF* | Tnf | Alliance of Genome Resources | ||||
| chronic obstructive pulmonary disease | XRCC5* | Xrcc5 | Alliance of Genome Resources | ||||
| pulmonary emphysema | CSF3* | Csf3 | Alliance of Genome Resources | ||||
| pulmonary emphysema | EPHX1* | Ephx1 | Alliance of Genome Resources | ||||
| pulmonary emphysema | GSTM1*, GSTM5 | Gstm1, Gstm2, Gstm3, Gstm6 | Alliance of Genome Resources | ||||
| pulmonary emphysema | GSTP1* | Gstp1, Gstp2, Gstp3, Gstp-ps | Alliance of Genome Resources | ||||
| pulmonary emphysema | HMOX1* | Hmox1 | Alliance of Genome Resources | ||||
| pulmonary emphysema | MMP1* | Mmp1a, Mmp1b | Alliance of Genome Resources | ||||
| pulmonary emphysema | MMP9* | Mmp9 | Alliance of Genome Resources | ||||
| pulmonary emphysema | SERPINA1* | Serpina1a, Serpina1b, Serpina1c, Serpina1d, Serpina1e | 4 models | Alliance of Genome Resources | |||
| pulmonary emphysema | SFTPC* | Sftpc | Alliance of Genome Resources | ||||
| pulmonary emphysema | TGFB1* | Tgfb1 | 1 model | Alliance of Genome Resources | |||
| pulmonary emphysema | CLPTM1L* | Clptm1l | Alliance of Genome Resources | ||||
Excel File
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Transgenes and other genome features developed in mice to model this disease.
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| Disease Term | Transgenes and Other Genome Features | Mouse Models | |
| pulmonary emphysema | Serpina1 | 4 models | |
| pulmonary emphysema | Tg(Actb-Ptma)T12Clwu | 2 models | |
| pulmonary emphysema | Tg(HP-MMP1a)34-1Cha | 2 models | |
| pulmonary emphysema | Tg(Msr1-MMP9)#Apar | 1 model | |
| pulmonary emphysema | Tg(tetO-PLAGL2)P3Ysy | 1 model | |