| Disease Term | Human Homologs | Mouse Homologs | Mouse Models | Homology Source | |||
  | multiple sclerosis | PRF1* | Prf1* | 1 model | Alliance of Genome Resources | ||
| multiple sclerosis | TNF* | Tnf* | 2 models | Alliance of Genome Resources | |||
| | multiple sclerosis | LRCH1 | Lrch1* | 1 model | Alliance of Genome Resources | ||
| | demyelinating disease | MYC* | Bmyc, Myc | Alliance of Genome Resources | |||
| demyelinating disease | KLK6* | Klk6 | Alliance of Genome Resources | ||||
| multiple sclerosis | A2M* | A2m | Alliance of Genome Resources | ||||
| multiple sclerosis | AGER* | Ager | Alliance of Genome Resources | ||||
| multiple sclerosis | APOC2* | Apoc2, Apoc2l | Alliance of Genome Resources | ||||
| multiple sclerosis | ATP6* | Atp6-ps, mt-Atp6 | Alliance of Genome Resources | ||||
| multiple sclerosis | CAV1* | Cav1 | Alliance of Genome Resources | ||||
| multiple sclerosis | CCL1* | Ccl1 | Alliance of Genome Resources | ||||
| multiple sclerosis | CCL2*, CCL13* | Ccl2, Ccl12 | Alliance of Genome Resources | ||||
| multiple sclerosis | CCL7* | Ccl7 | Alliance of Genome Resources | ||||
| multiple sclerosis | CCR5* | Ccr5 | Alliance of Genome Resources | ||||
| multiple sclerosis | CD24* | Cd24a | Alliance of Genome Resources | ||||
| multiple sclerosis | CD28* | Cd28 | Alliance of Genome Resources | ||||
| multiple sclerosis | CD40* | Cd40 | Alliance of Genome Resources | ||||
| multiple sclerosis | CD46* | Cd46 | Alliance of Genome Resources | ||||
| multiple sclerosis | CD86* | Cd86 | Alliance of Genome Resources | ||||
| multiple sclerosis | CIITA* | Ciita | Alliance of Genome Resources | ||||
| multiple sclerosis | CLEC16A* | Clec16a | Alliance of Genome Resources | ||||
| multiple sclerosis | CNP* | Cnp | Alliance of Genome Resources | ||||
| multiple sclerosis | CNTF* | Cntf | Alliance of Genome Resources | ||||
| multiple sclerosis | CTLA4* | Ctla4 | Alliance of Genome Resources | ||||
| multiple sclerosis | FAS* | Fas | Alliance of Genome Resources | ||||
| multiple sclerosis | FASLG* | Fasl | Alliance of Genome Resources | ||||
| multiple sclerosis | GABRA3* | Gabra3 | Alliance of Genome Resources | ||||
| multiple sclerosis | GC* | Gc | Alliance of Genome Resources | ||||
| multiple sclerosis | GSTM1*, GSTM5 | Gstm1, Gstm2, Gstm3, Gstm6 | Alliance of Genome Resources | ||||
| multiple sclerosis | GSTM3* | Gstm5 | Alliance of Genome Resources | ||||
| multiple sclerosis | GSTP1* | Gstp1, Gstp2, Gstp3, Gstp-ps | Alliance of Genome Resources | ||||
| multiple sclerosis | GSTT1* | Gstt1 | Alliance of Genome Resources | ||||
| multiple sclerosis | HLA-DQA1*, HLA-DQA2 | H2-Aa | 1 model | Alliance of Genome Resources | |||
| multiple sclerosis | HLA-DQB1*, HLA-DQB2 | H2-Ab1 | 1 model | Alliance of Genome Resources | |||
| multiple sclerosis | HLA-DRA* | H2-Ea | 1 model | Alliance of Genome Resources | |||
| multiple sclerosis | HLA-DRB1*, HLA-DRB3*, HLA-DRB4, HLA-DRB5 | H2-Eb1, H2-Eb2 | 1 model | Alliance of Genome Resources | |||
| multiple sclerosis | H6PD* | H6pd | Alliance of Genome Resources | ||||
| multiple sclerosis | HLA-DPB1* | ||||||
| multiple sclerosis | HSP90AB1*, HSP90AB2P, HSP90AB3P, HSP90AB4P | Hsp90ab1 | Alliance of Genome Resources | ||||
| multiple sclerosis | IFNB1* | Ifnb1 | Alliance of Genome Resources | ||||
| multiple sclerosis | IFNG* | Ifng | Alliance of Genome Resources | ||||
| multiple sclerosis | IL1B* | Il1b | Alliance of Genome Resources | ||||
| multiple sclerosis | IL2RA* | Il2ra | Alliance of Genome Resources | ||||
| multiple sclerosis | IL4* | Il4 | Alliance of Genome Resources | ||||
| multiple sclerosis | IL4R* | Il4ra | Alliance of Genome Resources | ||||
| multiple sclerosis | IL6* | Il6 | Alliance of Genome Resources | ||||
| multiple sclerosis | IL21R* | Il21r | Alliance of Genome Resources | ||||
| multiple sclerosis | IL23R* | Il23r | Alliance of Genome Resources | ||||
| multiple sclerosis | IRF5* | Irf5 | Alliance of Genome Resources | ||||
| multiple sclerosis | JAG1* | Jag1 | Alliance of Genome Resources | ||||
| multiple sclerosis | KIF1B* | Kif1b | Alliance of Genome Resources | ||||
| multiple sclerosis | KIF5A* | Kif5a | Alliance of Genome Resources | ||||
| multiple sclerosis | MBP* | Mbp | Alliance of Genome Resources | ||||
| multiple sclerosis | MMP9* | Mmp9 | Alliance of Genome Resources | ||||
| multiple sclerosis | MMP12* | Mmp12 | Alliance of Genome Resources | ||||
| multiple sclerosis | MOG* | Mog | 4 models | Alliance of Genome Resources | |||
| multiple sclerosis | MPHOSPH9* | Mphosph9 | Alliance of Genome Resources | ||||
| multiple sclerosis | ATP8* | mt-Atp8 | Alliance of Genome Resources | ||||
| multiple sclerosis | ND2* | mt-Nd2 | Alliance of Genome Resources | ||||
| multiple sclerosis | NDUFS2* | Ndufs2 | Alliance of Genome Resources | ||||
| multiple sclerosis | NECTIN2* | Nectin2 | Alliance of Genome Resources | ||||
| multiple sclerosis | NOTCH4* | Notch4 | Alliance of Genome Resources | ||||
| multiple sclerosis | PDCD1* | Pdcd1 | Alliance of Genome Resources | ||||
| multiple sclerosis | PHACTR2* | Phactr2 | Alliance of Genome Resources | ||||
| multiple sclerosis | PNMT* | Pnmt | Alliance of Genome Resources | ||||
| multiple sclerosis | POLG* | Polg | Alliance of Genome Resources | ||||
| multiple sclerosis | PSMB9* | Psmb9 | Alliance of Genome Resources | ||||
| multiple sclerosis | PTPRC* | Ptprc | Alliance of Genome Resources | ||||
| multiple sclerosis | RGMA* | Rgma | Alliance of Genome Resources | ||||
| multiple sclerosis | SH2D2A* | Sh2d2a | Alliance of Genome Resources | ||||
| multiple sclerosis | SLC11A1* | Slc11a1 | Alliance of Genome Resources | ||||
| multiple sclerosis | SPP1* | Spp1 | Alliance of Genome Resources | ||||
| multiple sclerosis | TAP2* | Tap2 | Alliance of Genome Resources | ||||
| multiple sclerosis | TNFRSF1A* | Tnfrsf1a | 1 model | Alliance of Genome Resources | |||
| multiple sclerosis | VDR* | Vdr | Alliance of Genome Resources | ||||
| primary progressive multiple sclerosis | HLA-DRB1*, HLA-DRB3, HLA-DRB4, HLA-DRB5 | H2-Eb1, H2-Eb2 | Alliance of Genome Resources | ||||
| primary progressive multiple sclerosis | IL4R* | Il4ra | Alliance of Genome Resources | ||||
| primary progressive multiple sclerosis | HLA-DQB1*, HLA-DQB2 | H2-Ab1 | Alliance of Genome Resources | ||||
| primary progressive multiple sclerosis | GRN* | Grn | Alliance of Genome Resources | ||||
| primary progressive multiple sclerosis | ADAMTS14* | Adamts14 | Alliance of Genome Resources | ||||
| relapsing-remitting multiple sclerosis | CSPG4* | Cspg4 | Alliance of Genome Resources | ||||
| relapsing-remitting multiple sclerosis | ADAMTS14* | Adamts14 | Alliance of Genome Resources | ||||
| relapsing-remitting multiple sclerosis | FAS* | Fas | Alliance of Genome Resources | ||||
| relapsing-remitting multiple sclerosis | KLC1* | Klc1 | Alliance of Genome Resources | ||||
| relapsing-remitting multiple sclerosis | NOD2* | Nod2 | Alliance of Genome Resources | ||||
Excel File
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Transgenes and other genome features developed in mice to model this disease.
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| Disease Term | Transgenes and Other Genome Features | Mouse Models | |
| multiple sclerosis | Tg(H2-Kb-Tcra,-Tcrb)1640Kurs | 1 model | |
| multiple sclerosis | Tg(Mbp-Pad2)28Fgm | 2 models | |
| multiple sclerosis | Tg(PLP1*)4Rsj | 1 model | |
| multiple sclerosis | Tg(Tnf)6074Gkl | 2 models | |
| multiple sclerosis | Tg(Gfap-TNF*)K21Gkl | 2 models | |