Disease Term | Human Homologs | Mouse Homologs | Mouse Models | Homology Source | |||
Noonan syndrome 1 | PTPN11* | Ptpn11* | 3 models | Alliance of Genome Resources | |||
Noonan syndrome 10 | LZTR1* | Lztr1* | 1 model | Alliance of Genome Resources | |||
Noonan syndrome 3 | KRAS* | Kras* | 1 model | Alliance of Genome Resources | |||
Noonan syndrome 4 | SOS1* | Sos1* | 2 models | Alliance of Genome Resources | |||
Noonan syndrome 5 | RAF1* | Raf1* | 2 models | Alliance of Genome Resources | |||
Noonan syndrome 8 | RIT1* | Rit1* | 1 model | Alliance of Genome Resources | |||
Noonan syndrome | KAT6B | Kat6b* | 1 model | Alliance of Genome Resources | |||
Noonan syndrome | APAF1 | Apaf1* | 1 model | Alliance of Genome Resources | |||
Noonan syndrome | KRAS* | Kras | Alliance of Genome Resources | ||||
Noonan syndrome | LZTR1* | Lztr1 | Alliance of Genome Resources | ||||
Noonan syndrome | PTPN11* | Ptpn11 | Alliance of Genome Resources | ||||
Noonan syndrome | RAF1* | Raf1 | Alliance of Genome Resources | ||||
Noonan syndrome | RASA2* | Rasa2 | Alliance of Genome Resources | ||||
Noonan syndrome | RIT1* | Rit1 | Alliance of Genome Resources | ||||
Noonan syndrome | SOS1* | Sos1 | Alliance of Genome Resources | ||||
Noonan syndrome | SPRED2* | Spred2 | Alliance of Genome Resources | ||||
Noonan syndrome 11 | MRAS* | Mras | Alliance of Genome Resources | ||||
Noonan syndrome 12 | RRAS2* | Rras2 | Alliance of Genome Resources | ||||
Noonan syndrome 13 | MAPK1* | Mapk1 | Alliance of Genome Resources | ||||
Noonan syndrome 2 | LZTR1* | Lztr1 | Alliance of Genome Resources | ||||
Noonan syndrome 6 | NRAS* | Nras | Alliance of Genome Resources | ||||
Noonan syndrome 7 | BRAF* | Braf | Alliance of Genome Resources | ||||
Noonan syndrome 9 | SOS2* | Sos2 | Alliance of Genome Resources |
Transgenes and other genome features developed in mice to model this disease.
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Disease Term | Transgenes and Other Genome Features | Mouse Models | |
Noonan syndrome 1 | Tg(CAG-cat,-Ptpn11*Q97R)1Rbns | 2 models | |
Noonan syndrome 1 | Tg(Myh7-Ptpn11*Q79R)11Rbns | 1 model |