| Disease Term | Human Homologs | Mouse Homologs | Mouse Models | Homology Source | |||
  | atypical teratoid rhabdoid tumor | SMARCB1* | Smarcb1* | 3 models | Alliance of Genome Resources | ||
| | glioblastoma | TP53 | Trp53* | 2 models | Alliance of Genome Resources | ||
| malignant astrocytoma | HRAS | Hras* | 1 model | Alliance of Genome Resources | |||
| medulloblastoma | SMO | Smo* | 8 models | Alliance of Genome Resources | |||
| medulloblastoma | PTCH1 | Ptch1* | 12 models | Alliance of Genome Resources | |||
| medulloblastoma | IFNG | Ifng* | 2 models | Alliance of Genome Resources | |||
| | astroblastoma | PIK3R1* | Pik3r1 | Alliance of Genome Resources | |||
| brain cancer | CDKN2B-AS1* | ||||||
| brain cancer | TERT* | Tert | Alliance of Genome Resources | ||||
| brain cancer | CCDC26* | ||||||
| brain glioma | PTPRB* | Ptprb | Alliance of Genome Resources | ||||
| brain glioma | ADAM3A* | Adam3 | Alliance of Genome Resources | ||||
| brain glioma | XRCC3* | Xrcc3 | Alliance of Genome Resources | ||||
| brain glioma | XRCC1* | Xrcc1 | Alliance of Genome Resources | ||||
| central nervous system cancer | XRCC3* | Xrcc3 | Alliance of Genome Resources | ||||
| central nervous system cancer | XRCC1* | Xrcc1 | Alliance of Genome Resources | ||||
| central nervous system lymphoma | MYD88* | Myd88 | Alliance of Genome Resources | ||||
| central nervous system lymphoma | IL10* | Il10 | Alliance of Genome Resources | ||||
| central nervous system lymphoma | CD79B* | Cd79b | Alliance of Genome Resources | ||||
| central nervous system lymphoma | BTK* | Btk | Alliance of Genome Resources | ||||
| childhood astrocytic tumor | RTEL1* | Rtel1 | Alliance of Genome Resources | ||||
| chordoid glioma | PRKCA* | Prkca | Alliance of Genome Resources | ||||
| familial meningioma | PTEN* | Pten | Alliance of Genome Resources | ||||
| familial meningioma | SMARCE1* | Smarce1 | Alliance of Genome Resources | ||||
| familial meningioma | PDGFB* | Pdgfb | Alliance of Genome Resources | ||||
| familial meningioma | MN1* | Mn1 | Alliance of Genome Resources | ||||
| familial meningioma | SUFU* | Sufu | Alliance of Genome Resources | ||||
| familial meningioma | NF2* | Nf2 | 1 model | Alliance of Genome Resources | |||
| glioblastoma | RB1* | Rb1 | Alliance of Genome Resources | ||||
| glioblastoma | ADGRB1* | Adgrb1 | Alliance of Genome Resources | ||||
| glioblastoma | AKT3* | Akt3 | Alliance of Genome Resources | ||||
| glioblastoma | ARRB2* | Arrb2 | Alliance of Genome Resources | ||||
| glioblastoma | CDK4* | Cdk4 | Alliance of Genome Resources | ||||
| glioblastoma | CDKN2A* | Cdkn2a | Alliance of Genome Resources | ||||
| glioblastoma | DMBT1* | Dmbt1 | Alliance of Genome Resources | ||||
| glioblastoma | EGF* | Egf | Alliance of Genome Resources | ||||
| glioblastoma | EZH2* | Ezh2 | Alliance of Genome Resources | ||||
| glioblastoma | FLT3LG* | Flt3l | Alliance of Genome Resources | ||||
| glioblastoma | FXN* | Fxn | Alliance of Genome Resources | ||||
| glioblastoma | IDH1* | Idh1 | Alliance of Genome Resources | ||||
| glioblastoma | KDR* | Kdr | Alliance of Genome Resources | ||||
| glioblastoma | LZTR1* | Lztr1 | Alliance of Genome Resources | ||||
| glioblastoma | MAP1LC3A* | Map1lc3a | Alliance of Genome Resources | ||||
| glioblastoma | MDM2* | Mdm2 | Alliance of Genome Resources | ||||
| glioblastoma | MGMT* | Mgmt | Alliance of Genome Resources | ||||
| glioblastoma | MMP9* | Mmp9 | Alliance of Genome Resources | ||||
| glioblastoma | NFKBIA* | Nfkbia | Alliance of Genome Resources | ||||
| glioblastoma | NRAS* | Nras | Alliance of Genome Resources | ||||
| glioblastoma | PDGFB* | Pdgfb | Alliance of Genome Resources | ||||
| glioblastoma | PDGFRB* | Pdgfrb | Alliance of Genome Resources | ||||
| glioblastoma | PGF* | Pgf | Alliance of Genome Resources | ||||
| glioblastoma | PIK3CB* | Pik3cb | Alliance of Genome Resources | ||||
| glioblastoma | PTPRB* | Ptprb | Alliance of Genome Resources | ||||
| glioblastoma | RPL5* | Rpl5 | Alliance of Genome Resources | ||||
| glioblastoma | XRCC1* | Xrcc1 | Alliance of Genome Resources | ||||
| malignant astrocytoma | BRAF* | Braf | Alliance of Genome Resources | ||||
| malignant astrocytoma | CADM2* | Cadm2 | Alliance of Genome Resources | ||||
| malignant astrocytoma | GSTP1* | Gstp1, Gstp2, Gstp3, Gstp-ps | Alliance of Genome Resources | ||||
| malignant astrocytoma | GSTM1*, GSTM5 | Gstm1, Gstm2, Gstm3, Gstm6 | Alliance of Genome Resources | ||||
| malignant astrocytoma | KRAS* | Kras | Alliance of Genome Resources | ||||
| medulloblastoma | BRCA2* | Brca2 | 2 models | Alliance of Genome Resources | |||
| medulloblastoma | CTNNB1* | Ctnnb1 | Alliance of Genome Resources | ||||
| medulloblastoma | ELP1* | Elp1 | Alliance of Genome Resources | ||||
| medulloblastoma | GPR161* | Gpr161 | Alliance of Genome Resources | ||||
| medulloblastoma | GSTM1*, GSTM5 | Gstm1, Gstm2, Gstm3, Gstm6 | Alliance of Genome Resources | ||||
| medulloblastoma | GSTT1* | Gstt1 | Alliance of Genome Resources | ||||
| medulloblastoma | PTCH2* | Ptch2 | 2 models | Alliance of Genome Resources | |||
| medulloblastoma | SUFU* | Sufu | 1 model | Alliance of Genome Resources | |||
| medulloblastoma | TSC2* | Tsc2 | Alliance of Genome Resources | ||||
| medulloblastoma | APC* | Apc | Alliance of Genome Resources | ||||
| meningioma | NF2* | Nf2 | Alliance of Genome Resources | ||||
| meningioma | SMARCE1* | Smarce1 | Alliance of Genome Resources | ||||
| meningioma | MTRR* | Mtrr | Alliance of Genome Resources | ||||
| meningioma | XRCC1* | Xrcc1 | Alliance of Genome Resources | ||||
| meningioma | XRCC3* | Xrcc3 | Alliance of Genome Resources | ||||
| meningioma | SMARCB1* | Smarcb1 | Alliance of Genome Resources | ||||
| meningioma | MN1* | Mn1 | Alliance of Genome Resources | ||||
| meningioma | GSTM3* | Gstm5 | Alliance of Genome Resources | ||||
| optic nerve glioma | NF1* | Nf1 | Alliance of Genome Resources | ||||
Excel File
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Transgenes and other genome features developed in mice to model this disease.
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| Disease Term | Transgenes and Other Genome Features | Mouse Models | |
| malignant astrocytoma | Tg(GFAP-Hras1)2Agu | 1 model | |
| malignant astrocytoma | Tg(GFAP-SRC)1Aag | 1 model | |
| malignant astrocytoma | Tg(GFAP-SRC)2Aag | 1 model | |
| malignant astrocytoma | Tg(GFAP-TAg121)1Tvd | 2 models | |
| medulloblastoma | Tg(Neurod2-Smo*A1)199Jols | 3 models | |
| medulloblastoma | Tg(Neurod2-Smo*A2)#Jols | 1 model | |
| medulloblastoma | Tg(tetO-Ifng)184Pop | 2 models | |
| medulloblastoma | Tg(tetO-MYCN,-luc)#Waw | 2 models | |
| medulloblastoma | Tg(tetO-TAg,CMV-rtTA)123Yihu | 1 model | |