Disease Term | Human Homologs | Mouse Homologs | Mouse Models | Homology Source | |||
progeria | LMNA* | Lmna* | 14 models | Alliance of Genome Resources | |||
progeria | SIRT6 | Sirt6* | 1 model | Alliance of Genome Resources | |||
progeria | VCPIP1 | Vcpip1* | 1 model | Alliance of Genome Resources | |||
progeria | ZMPSTE24 | Zmpste24* | 3 models | Alliance of Genome Resources | |||
progeria | GH1*, CSH1, CSH2, CSHL1, GH2 | Gh | Alliance of Genome Resources |
Transgenes and other genome features developed in mice to model this disease.
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Disease Term | Transgenes and Other Genome Features | Mouse Models | |
progeria | Tg(LMNA*G608G)HClns | 1 model | |
progeria | Tg(tetO-LMNA*G608G,-EGFP)VF1-07Maer | 1 model |