| Disease Term | Human Homologs | Mouse Homologs | Mouse Models | Homology Source | |||
  | amelogenesis imperfecta hypomaturation type 2A2 | MMP20* | Mmp20* | 1 model | Alliance of Genome Resources | ||
| amelogenesis imperfecta hypomaturation type 2A3 | WDR72* | Wdr72* | 1 model | Alliance of Genome Resources | |||
| amelogenesis imperfecta type 1B | ENAM* | Enam* | 6 models | Alliance of Genome Resources | |||
| amelogenesis imperfecta type 1E | AMELX*, AMELY | Amelx* | 6 models | Alliance of Genome Resources | |||
| amelogenesis imperfecta type 3C | RELT* | Relt* | 1 model | Alliance of Genome Resources | |||
| cleft lip | IRF6* | Irf6* | 1 model | Alliance of Genome Resources | |||
| dentinogenesis imperfecta | DSPP* | Dspp* | 1 model | Alliance of Genome Resources | |||
| tooth agenesis | MSX1* | Msx1* | 3 models | Alliance of Genome Resources | |||
| tooth agenesis | PAX9* | Pax9* | 2 models | Alliance of Genome Resources | |||
| | aggressive periodontitis | POSTN | Postn* | 1 model | Alliance of Genome Resources | ||
| ankyloglossia | LGR5 | Lgr5* | 1 model | Alliance of Genome Resources | |||
| dentin dysplasia | SSUH2 | Ssu2* | 2 models | Alliance of Genome Resources | |||
| periodontal disease | DSPP | Dspp* | 1 model | Alliance of Genome Resources | |||
| salivary gland cancer | GON4L, YY1AP1 | Gon4l* | 1 model | Alliance of Genome Resources | |||
| | aggressive periodontitis | CTSC* | Ctsc | Alliance of Genome Resources | |||
| aggressive periodontitis | GSTM1*, GSTM5 | Gstm1, Gstm2, Gstm3, Gstm6 | Alliance of Genome Resources | ||||
| aggressive periodontitis | IL6* | Il6 | Alliance of Genome Resources | ||||
| aggressive periodontitis | CCL2*, CCL13 | Ccl2, Ccl12 | Alliance of Genome Resources | ||||
| aggressive periodontitis | IL1R2* | Il1r2 | Alliance of Genome Resources | ||||
| aggressive periodontitis | GSTT1* | Gstt1 | Alliance of Genome Resources | ||||
| aggressive periodontitis | CCR2* | Ccr2 | Alliance of Genome Resources | ||||
| aggressive periodontitis | IL10* | Il10 | Alliance of Genome Resources | ||||
| aggressive periodontitis | COL1A1* | Col1a1 | Alliance of Genome Resources | ||||
| amelogenesis imperfecta | AMELX*, AMELY | Amelx | Alliance of Genome Resources | ||||
| amelogenesis imperfecta | FAM20C* | Fam20c | Alliance of Genome Resources | ||||
| amelogenesis imperfecta hypomaturation type 2A4 | ODAPH* | Odaph | Alliance of Genome Resources | ||||
| amelogenesis imperfecta hypomaturation type 2A5 | SLC24A4* | Slc24a4 | Alliance of Genome Resources | ||||
| amelogenesis imperfecta type 1A | LAMB3* | Lamb3 | Alliance of Genome Resources | ||||
| amelogenesis imperfecta type 1C | ENAM* | Enam | Alliance of Genome Resources | ||||
| amelogenesis imperfecta type 1F | AMBN* | Ambn | Alliance of Genome Resources | ||||
| amelogenesis imperfecta type 1G | FAM20A* | Fam20a | Alliance of Genome Resources | ||||
| amelogenesis imperfecta type 1H | ITGB6* | Itgb6 | Alliance of Genome Resources | ||||
| amelogenesis imperfecta type 1J | ACP4* | Acp4 | Alliance of Genome Resources | ||||
| amelogenesis imperfecta type 1K | SP6* | Sp6 | Alliance of Genome Resources | ||||
| amelogenesis imperfecta type 2A1 | KLK4* | Klk4 | Alliance of Genome Resources | ||||
| amelogenesis imperfecta type 2A6 | GPR68* | Gpr68 | Alliance of Genome Resources | ||||
| amelogenesis imperfecta type 3A | FAM83H* | Fam83h | Alliance of Genome Resources | ||||
| amelogenesis imperfecta type 3B | AMTN* | Amtn | Alliance of Genome Resources | ||||
| amelogenesis imperfecta type 4 | DLX3* | Dlx3 | Alliance of Genome Resources | ||||
| anodontia | MSX1* | Msx1 | Alliance of Genome Resources | ||||
| anodontia | MMP13* | Mmp13 | Alliance of Genome Resources | ||||
| anodontia | MMP9* | Mmp9 | Alliance of Genome Resources | ||||
| anodontia | GLI3* | Gli3 | Alliance of Genome Resources | ||||
| anodontia | DKK1* | Dkk1 | Alliance of Genome Resources | ||||
| aphthous stomatitis | HFE* | Hfe | Alliance of Genome Resources | ||||
| aphthous stomatitis | TGFB1* | Tgfb1 | Alliance of Genome Resources | ||||
| aphthous stomatitis | MTHFR* | Mthfr | Alliance of Genome Resources | ||||
| aphthous stomatitis | IL10* | Il10 | Alliance of Genome Resources | ||||
| cleft lip | KIF7* | Kif7 | Alliance of Genome Resources | ||||
| cleft lip | SDC2* | Sdc2 | Alliance of Genome Resources | ||||
| cleft lip | BMP4* | Bmp4 | Alliance of Genome Resources | ||||
| cleft lip | CDH1* | Cdh1 | Alliance of Genome Resources | ||||
| cleft lip | FGF1* | Fgf1 | Alliance of Genome Resources | ||||
| cleft lip | FGFR1* | Fgfr1 | Alliance of Genome Resources | ||||
| cleft lip | GDF6* | Gdf6 | Alliance of Genome Resources | ||||
| cleft lip | MSX1* | Msx1 | Alliance of Genome Resources | ||||
| cleft lip | MTHFD1* | Mthfd1 | Alliance of Genome Resources | ||||
| cleft lip | MTHFR* | Mthfr | Alliance of Genome Resources | ||||
| cleft lip | NECTIN1* | Nectin1 | Alliance of Genome Resources | ||||
| cleft lip | NOG* | Nog | Alliance of Genome Resources | ||||
| cleft lip | POMT1* | Pomt1 | Alliance of Genome Resources | ||||
| cleft lip | SLC19A1* | Slc19a1 | Alliance of Genome Resources | ||||
| dental caries | HLA-DQB1*, HLA-DQB2 | H2-Ab1 | Alliance of Genome Resources | ||||
| dental caries | BCOR*, BCORP1 | Bcor | Alliance of Genome Resources | ||||
| dental caries | IL1B* | Il1b | Alliance of Genome Resources | ||||
| dentinogenesis imperfecta | COL1A1* | Col1a1 | Alliance of Genome Resources | ||||
| gingival fibromatosis | SOS1* | Sos1 | Alliance of Genome Resources | ||||
| gingival fibromatosis 5 | REST* | Rest | Alliance of Genome Resources | ||||
| oral cavity cancer | CYP1A1* | Cyp1a1 | Alliance of Genome Resources | ||||
| oral cavity cancer | CHRNB4* | Chrnb4 | Alliance of Genome Resources | ||||
| oral cavity cancer | CYP2E1* | Cyp2e1 | Alliance of Genome Resources | ||||
| oral cavity cancer | GSTM1*, GSTM5 | Gstm1, Gstm2, Gstm3, Gstm6 | Alliance of Genome Resources | ||||
| oral cavity cancer | GSTT1* | Gstt1 | Alliance of Genome Resources | ||||
| oral cavity cancer | SOD3* | Sod3 | Alliance of Genome Resources | ||||
| oral mucosa leukoplakia | XRCC1* | Xrcc1 | Alliance of Genome Resources | ||||
| oral mucosa leukoplakia | CDKN1A* | Cdkn1a | Alliance of Genome Resources | ||||
| oral mucosa leukoplakia | ERCC2* | Ercc2 | Alliance of Genome Resources | ||||
| oral mucosa leukoplakia | GSTM1*, GSTM5 | Gstm1, Gstm2, Gstm3, Gstm6 | Alliance of Genome Resources | ||||
| oral mucosa leukoplakia | GSTT1* | Gstt1 | Alliance of Genome Resources | ||||
| oral mucosa leukoplakia | NAT2*, NAT1 | Nat1, Nat2, Nat3 | Alliance of Genome Resources | ||||
| oral squamous cell carcinoma | BARHL2* | Barhl2 | Alliance of Genome Resources | ||||
| oral squamous cell carcinoma | FGFR3* | Fgfr3 | Alliance of Genome Resources | ||||
| oral squamous cell carcinoma | FAT1* | Fat1 | Alliance of Genome Resources | ||||
| oral squamous cell carcinoma | EZH2* | Ezh2 | Alliance of Genome Resources | ||||
| oral squamous cell carcinoma | DNMT3B* | Dnmt3b | Alliance of Genome Resources | ||||
| oral squamous cell carcinoma | DDR2* | Ddr2 | Alliance of Genome Resources | ||||
| oral squamous cell carcinoma | DAXX* | Daxx | Alliance of Genome Resources | ||||
| oral squamous cell carcinoma | CYP24A1* | Cyp24a1 | Alliance of Genome Resources | ||||
| oral squamous cell carcinoma | CYP2E1* | Cyp2e1 | Alliance of Genome Resources | ||||
| oral squamous cell carcinoma | CYP1A1* | Cyp1a1 | Alliance of Genome Resources | ||||
| oral squamous cell carcinoma | CLPTM1L* | Clptm1l | Alliance of Genome Resources | ||||
| oral squamous cell carcinoma | CDKN1A* | Cdkn1a | Alliance of Genome Resources | ||||
| oral squamous cell carcinoma | CCR2* | Ccr2 | Alliance of Genome Resources | ||||
| oral squamous cell carcinoma | CCL2*, CCL13 | Ccl2, Ccl12 | Alliance of Genome Resources | ||||
| oral squamous cell carcinoma | BRINP2* | Brinp2 | Alliance of Genome Resources | ||||
| oral squamous cell carcinoma | FGFR4* | Fgfr4 | Alliance of Genome Resources | ||||
| oral squamous cell carcinoma | AXIN2* | Axin2 | Alliance of Genome Resources | ||||
| oral squamous cell carcinoma | ABL1* | Abl1 | Alliance of Genome Resources | ||||
| oral squamous cell carcinoma | WNT11* | Wnt11 | Alliance of Genome Resources | ||||
| oral squamous cell carcinoma | TP53* | Trp53 | Alliance of Genome Resources | ||||
| oral squamous cell carcinoma | TERT* | Tert | Alliance of Genome Resources | ||||
| oral squamous cell carcinoma | MTHFR* | Mthfr | Alliance of Genome Resources | ||||
| oral squamous cell carcinoma | MIR222* | Mir222 | Alliance of Genome Resources | ||||
| oral squamous cell carcinoma | MIR221* | Mir221 | Alliance of Genome Resources | ||||
| oral squamous cell carcinoma | IL10* | Il10 | Alliance of Genome Resources | ||||
| oral squamous cell carcinoma | IL2* | Il2 | Alliance of Genome Resources | ||||
| oral squamous cell carcinoma | GSTM1*, GSTM5 | Gstm1, Gstm2, Gstm3, Gstm6 | Alliance of Genome Resources | ||||
| oral squamous cell carcinoma | GSK3B* | Gsk3b | Alliance of Genome Resources | ||||
| oral submucous fibrosis | GSTT1* | Gstt1 | Alliance of Genome Resources | ||||
| oral submucous fibrosis | GSTM1*, GSTM5 | Gstm1, Gstm2, Gstm3, Gstm6 | Alliance of Genome Resources | ||||
| Papillon-Lefevre disease | CTSC* | Ctsc | Alliance of Genome Resources | ||||
| periodontal disease | IL6* | Il6 | Alliance of Genome Resources | ||||
| periodontitis | ELANE* | Elane | Alliance of Genome Resources | ||||
| periodontitis | GNRH1* | Gnrh1 | Alliance of Genome Resources | ||||
| periodontitis | GSTM1*, GSTM5 | Gstm1, Gstm2, Gstm3, Gstm6 | Alliance of Genome Resources | ||||
| periodontitis | IL1RN* | Il1rn | Alliance of Genome Resources | ||||
| periodontitis | CYP1A1* | Cyp1a1 | Alliance of Genome Resources | ||||
| periodontitis | IL6* | Il6 | Alliance of Genome Resources | ||||
| periodontitis | ADRB1* | Adrb1 | Alliance of Genome Resources | ||||
| primary failure of tooth eruption | PTH1R* | Pth1r | Alliance of Genome Resources | ||||
| salivary gland adenoid cystic carcinoma | XRCC4* | Xrcc4 | Alliance of Genome Resources | ||||
| salivary gland carcinoma | RAD52* | Rad52 | Alliance of Genome Resources | ||||
| salivary gland carcinoma | XRCC4* | Xrcc4 | Alliance of Genome Resources | ||||
| solitary median maxillary central incisor | SHH* | Shh | Alliance of Genome Resources | ||||
| tooth agenesis | BMP4* | Bmp4 | Alliance of Genome Resources | ||||
| tooth agenesis | BMP2* | Bmp2 | Alliance of Genome Resources | ||||
| tooth agenesis | WNT10B* | Wnt10b | Alliance of Genome Resources | ||||
| tooth agenesis | WNT10A* | Wnt10a | Alliance of Genome Resources | ||||
| tooth agenesis | LRP6* | Lrp6 | Alliance of Genome Resources | ||||
| tooth agenesis | GREM2* | Grem2 | Alliance of Genome Resources | ||||
| tooth agenesis | EDA* | Eda | Alliance of Genome Resources | ||||
| tooth agenesis | TSPEAR* | Tspear | Alliance of Genome Resources | ||||
Excel File
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Transgenes and other genome features developed in mice to model this disease.
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| Disease Term | Transgenes and Other Genome Features | Mouse Models | |
| amelogenesis imperfecta | Tg(Amelx-Ambn)1Mlp | 1 model | |
| amelogenesis imperfecta type 1E | Tg(AMELX*P70T)2Gibs | 2 models | |
| dentin dysplasia | Tg(Dspp-TGFB1)3Kul | 1 model | |