| Disease Term | Human Homologs | Mouse Homologs | Mouse Models | Homology Source | |||
  | age related macular degeneration 12 | CX3CR1* | Cx3cr1* | 2 models | Alliance of Genome Resources | ||
| age related macular degeneration 4 | CFH* | Cfh*, Cfhr4 | 1 model | Alliance of Genome Resources | |||
| bestrophinopathy | BEST1* | Best1* | 2 models | Alliance of Genome Resources | |||
| Doyne honeycomb retinal dystrophy | EFEMP1* | Efemp1* | 4 models | Alliance of Genome Resources | |||
| patterned macular dystrophy 1 | PRPH2* | Prph2* | 4 models | Alliance of Genome Resources | |||
| patterned macular dystrophy 2 | CTNNA1* | Ctnna1* | 2 models | Alliance of Genome Resources | |||
| vitelliform macular dystrophy | BEST1* | Best1* | 2 models | Alliance of Genome Resources | |||
| vitelliform macular dystrophy | IMPG2* | Impg2* | 1 model | Alliance of Genome Resources | |||
| | age related macular degeneration | CCR2 | Ccr2* | 1 model | Alliance of Genome Resources | ||
| age related macular degeneration | PPARGC1A | Ppargc1a* | 1 model | Alliance of Genome Resources | |||
| age related macular degeneration | CCL2, CCL13 | Ccl2*, Ccl12 | 3 models | Alliance of Genome Resources | |||
| age related macular degeneration | CD46 | Cd46* | 1 model | Alliance of Genome Resources | |||
| age related macular degeneration 1 | VLDLR | Vldlr* | 1 model | Alliance of Genome Resources | |||
| age related macular degeneration 1 | CRYBA1 | Cryba1* | 1 model | Alliance of Genome Resources | |||
| Stargardt disease | ELOVL4 | Elovl4* | 2 models | Alliance of Genome Resources | |||
| Stargardt disease | ABCA4 | Abca4* | 5 models | Alliance of Genome Resources | |||
| | age related macular degeneration | HTRA1* | Htra1 | Alliance of Genome Resources | |||
| age related macular degeneration | FBLN5* | Fbln5 | Alliance of Genome Resources | ||||
| age related macular degeneration 1 | APOE* | Apoe | 1 model | Alliance of Genome Resources | |||
| age related macular degeneration 1 | CFHR1*, CFHR2 | Cfhr1 | Alliance of Genome Resources | ||||
| age related macular degeneration 1 | CFHR3* | Cfhr2 | Alliance of Genome Resources | ||||
| age related macular degeneration 1 | HMCN1* | Hmcn1 | Alliance of Genome Resources | ||||
| age related macular degeneration 11 | CST3* | Cst3 | Alliance of Genome Resources | ||||
| age related macular degeneration 13 | CFI* | Cfi | Alliance of Genome Resources | ||||
| age related macular degeneration 14 | CFB* | Cfb | Alliance of Genome Resources | ||||
| age related macular degeneration 14 | C2* | C2 | Alliance of Genome Resources | ||||
| age related macular degeneration 15 | C9* | C9 | Alliance of Genome Resources | ||||
| age related macular degeneration 2 | ABCA4* | Abca4 | 1 model | Alliance of Genome Resources | |||
| age related macular degeneration 5 | ERCC6* | Ercc6 | Alliance of Genome Resources | ||||
| age related macular degeneration 6 | RAX2* | ||||||
| age related macular degeneration 7 | HTRA1* | Htra1 | Alliance of Genome Resources | ||||
| age related macular degeneration 7 | C3* | C3 | Alliance of Genome Resources | ||||
| age related macular degeneration 8 | ARMS2* | ||||||
| age related macular degeneration 9 | C3* | C3 | Alliance of Genome Resources | ||||
| basal laminar drusen | CFH* | Cfh, Cfhr4 | Alliance of Genome Resources | ||||
| Kuhnt-Junius degeneration | GSTT1* | Gstt1 | Alliance of Genome Resources | ||||
| Kuhnt-Junius degeneration | HTRA1* | Htra1 | Alliance of Genome Resources | ||||
| Kuhnt-Junius degeneration | C3* | C3 | Alliance of Genome Resources | ||||
| Kuhnt-Junius degeneration | LOXL1* | Loxl1 | Alliance of Genome Resources | ||||
| Kuhnt-Junius degeneration | MTHFR* | Mthfr | Alliance of Genome Resources | ||||
| Kuhnt-Junius degeneration | NOS3* | Nos3 | Alliance of Genome Resources | ||||
| Kuhnt-Junius degeneration | PON1* | Pon1 | Alliance of Genome Resources | ||||
| Kuhnt-Junius degeneration | SOD2* | Sod2 | Alliance of Genome Resources | ||||
| Kuhnt-Junius degeneration | VEGFA* | Vegfa | Alliance of Genome Resources | ||||
| Kuhnt-Junius degeneration | KDR* | Kdr | Alliance of Genome Resources | ||||
| Kuhnt-Junius degeneration | APOE* | Apoe | Alliance of Genome Resources | ||||
| Kuhnt-Junius degeneration | CFI* | Cfi | Alliance of Genome Resources | ||||
| Kuhnt-Junius degeneration | CRP* | Crp | Alliance of Genome Resources | ||||
| Kuhnt-Junius degeneration | ELN* | Eln | Alliance of Genome Resources | ||||
| Kuhnt-Junius degeneration | FLT1* | Flt1 | Alliance of Genome Resources | ||||
| Kuhnt-Junius degeneration | GSTM1*, GSTM5 | Gstm1, Gstm2, Gstm3, Gstm6 | Alliance of Genome Resources | ||||
| Kuhnt-Junius degeneration | GSTP1* | Gstp1, Gstp2, Gstp3, Gstp-ps | Alliance of Genome Resources | ||||
| macular degeneration | IL17A* | Il17a | Alliance of Genome Resources | ||||
| macular degeneration | ABCA4* | Abca4 | Alliance of Genome Resources | ||||
| macular degeneration | ADIPOR1* | Adipor1 | Alliance of Genome Resources | ||||
| macular degeneration | APOE* | Apoe | Alliance of Genome Resources | ||||
| macular degeneration | BEST1* | Best1 | Alliance of Genome Resources | ||||
| macular degeneration | C2* | C2 | Alliance of Genome Resources | ||||
| macular degeneration | C3* | C3 | Alliance of Genome Resources | ||||
| macular degeneration | CACNG3* | Cacng3 | Alliance of Genome Resources | ||||
| macular degeneration | CFB* | Cfb | Alliance of Genome Resources | ||||
| macular degeneration | CFH* | Cfh, Cfhr4 | Alliance of Genome Resources | ||||
| macular degeneration | CFI* | Cfi | Alliance of Genome Resources | ||||
| macular degeneration | CRP* | Crp | Alliance of Genome Resources | ||||
| macular degeneration | CX3CR1* | Cx3cr1 | Alliance of Genome Resources | ||||
| macular degeneration | ERCC2* | Ercc2 | Alliance of Genome Resources | ||||
| macular degeneration | ESR1* | Esr1 | Alliance of Genome Resources | ||||
| macular degeneration | GSR* | Gsr | Alliance of Genome Resources | ||||
| macular degeneration | GSTM1*, GSTM5 | Gstm1, Gstm2, Gstm3, Gstm6 | Alliance of Genome Resources | ||||
| macular degeneration | KDR* | Kdr | Alliance of Genome Resources | ||||
| macular degeneration | MMP2* | Mmp2 | Alliance of Genome Resources | ||||
| macular degeneration | ND4* | mt-Nd4 | Alliance of Genome Resources | ||||
| macular degeneration | NFE2L2* | Nfe2l2 | Alliance of Genome Resources | ||||
| macular degeneration | NQO1* | Nqo1 | Alliance of Genome Resources | ||||
| macular degeneration | PON1* | Pon1 | Alliance of Genome Resources | ||||
| macular degeneration | PPARGC1A* | Ppargc1a | Alliance of Genome Resources | ||||
| macular degeneration | PRPH2* | Prph2 | Alliance of Genome Resources | ||||
| macular degeneration | SAMD7* | Samd7 | Alliance of Genome Resources | ||||
| macular degeneration | SERPING1* | Serping1 | Alliance of Genome Resources | ||||
| macular degeneration | TLR4* | Tlr4 | Alliance of Genome Resources | ||||
| occult macular dystrophy | RP1L1* | Rp1l1 | Alliance of Genome Resources | ||||
| patterned macular dystrophy | HTRA1* | Htra1 | Alliance of Genome Resources | ||||
| patterned macular dystrophy | PRPH2* | Prph2 | Alliance of Genome Resources | ||||
| patterned macular dystrophy 3 | MAPKAPK3* | Mapkapk3 | Alliance of Genome Resources | ||||
| retinal drusen | CFH* | Cfh, Cfhr4 | Alliance of Genome Resources | ||||
| retinal macular dystrophy 2 | PROM1* | Prom1 | Alliance of Genome Resources | ||||
| retinal macular dystrophy 4 | CLEC3B* | Clec3b | Alliance of Genome Resources | ||||
| vitelliform macular dystrophy | HTRA1* | Htra1 | Alliance of Genome Resources | ||||
| vitelliform macular dystrophy | PRPH2* | Prph2 | Alliance of Genome Resources | ||||
| vitelliform macular dystrophy | IMPG1* | Impg1 | Alliance of Genome Resources | ||||
| X-linked atrophic macular degeneration | RPGR* | Rpgr | Alliance of Genome Resources | ||||
Excel File
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Transgenes and other genome features developed in mice to model this disease.
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| Disease Term | Transgenes and Other Genome Features | Mouse Models | |
| age related macular degeneration 1 | Tg(APOB)1102Sgy | 1 model | |
| Stargardt disease | Tg(RBP3-ELOVL4*)2Kzh | 1 model | |
| Stargardt disease | Tg(RBP3-ELOVL4*)1Kzh | 1 model | |
| Stargardt disease | Tg(RBP3-ELOVL4*)3Kzh | 1 model | |