Disease Term | Human Homologs | Mouse Homologs | Mouse Models | Homology Source | |||
adrenocorticotropic hormone deficiency | TBX19* | Tbx19* | 1 model | Alliance of Genome Resources | |||
hypopituitarism | PROP1* | Prop1* | 2 models | Alliance of Genome Resources | |||
isolated growth hormone deficiency type II | GH1*, CSH1, CSH2, CSHL1, GH2 | Gh* | 2 models | Alliance of Genome Resources | |||
growth hormone secreting pituitary adenoma | MEN1 | Men1* | 1 model | Alliance of Genome Resources | |||
hypopituitarism | SMPD3 | Smpd3* | 1 model | Alliance of Genome Resources | |||
hypopituitarism | LHX3 | Lhx3* | 1 model | Alliance of Genome Resources | |||
hypopituitarism | HESX1 | Hesx1* | 1 model | Alliance of Genome Resources | |||
isolated growth hormone deficiency type IA | GHRH | Ghrh* | 1 model | Alliance of Genome Resources | |||
pituitary-dependent Cushing's disease | SCG5 | Scg5* | 1 model | Alliance of Genome Resources | |||
prolactinoma | MEN1 | Men1* | 1 model | Alliance of Genome Resources | |||
ACTH-secreting pituitary adenoma | USP8* | Usp8 | Alliance of Genome Resources | ||||
growth hormone secreting pituitary adenoma 2 | GPR101* | Gpr101 | Alliance of Genome Resources | ||||
hypopituitarism | MTHFR* | Mthfr | Alliance of Genome Resources | ||||
isolated growth hormone deficiency | GH1*, CSH1, CSH2, CSHL1, GH2 | Gh | Alliance of Genome Resources | ||||
isolated growth hormone deficiency | GHR* | Ghr | Alliance of Genome Resources | ||||
isolated growth hormone deficiency | GHRHR* | Ghrhr | Alliance of Genome Resources | ||||
isolated growth hormone deficiency type IA | GH1*, CSH1, CSH2, CSHL1, GH2 | Gh | Alliance of Genome Resources | ||||
isolated growth hormone deficiency type IA | DNA2* | Dna2 | Alliance of Genome Resources | ||||
isolated growth hormone deficiency type IB | GH1*, CSH1, CSH2, CSHL1, GH2 | Gh | Alliance of Genome Resources | ||||
isolated growth hormone deficiency type IB | GHRHR* | Ghrhr | Alliance of Genome Resources | ||||
isolated growth hormone deficiency type III | BTK* | Btk | Alliance of Genome Resources | ||||
panhypopituitarism | POU1F1* | Pou1f1 | Alliance of Genome Resources | ||||
panhypopituitarism | RNPC3* | Rnpc3 | Alliance of Genome Resources | ||||
panhypopituitarism | ROBO1* | Robo1 | Alliance of Genome Resources | ||||
panhypopituitarism | OTX2* | Otx2 | Alliance of Genome Resources | ||||
panhypopituitarism | LHX4* | Lhx4 | Alliance of Genome Resources | ||||
panhypopituitarism | LHX3* | Lhx3 | Alliance of Genome Resources | ||||
panhypopituitarism | PROP1* | Prop1 | Alliance of Genome Resources | ||||
pituitary adenoma 1 | AIP* | Aip | Alliance of Genome Resources | ||||
pituitary adenoma 3 | GNAS* | Gnas | Alliance of Genome Resources | ||||
pituitary adenoma 5 | CDH23* | Cdh23 | Alliance of Genome Resources | ||||
pituitary gland disease | POU1F1* | Pou1f1 | Alliance of Genome Resources | ||||
X-linked panhypopituitarism | SOX3* | Sox3 | Alliance of Genome Resources |
Transgenes and other genome features developed in mice to model this disease.
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Disease Term | Transgenes and Other Genome Features | Mouse Models | |
acromegaly | Tg(Mt1-GH1)#Jjk | 1 model | |
ACTH-secreting pituitary adenoma | Tg(PyLT)1Vb | 1 model | |
prolactinoma | Tg(Prl-EGFR)#Sme | 1 model |