| Disease Term | Human Homologs | Mouse Homologs | Mouse Models | Homology Source | |||
  | congenital nystagmus 1 | FRMD7* | Frmd7* | 2 models | Alliance of Genome Resources | ||
| Duane retraction syndrome | CHN1* | Chn1* | 1 model | Alliance of Genome Resources | |||
| Duane retraction syndrome | MAFB* | Mafb* | 2 models | Alliance of Genome Resources | |||
| Leber hereditary optic neuropathy | ND6* | mt-Nd6* | 1 model | Alliance of Genome Resources | |||
| optic atrophy | OPA1* | Opa1* | 3 models | Alliance of Genome Resources | |||
| | congenital fibrosis of the extraocular muscles | KIF21A | Kif21a* | 3 models | Alliance of Genome Resources | ||
| congenital fibrosis of the extraocular muscles | TUBB3 | Tubb3* | 1 model | Alliance of Genome Resources | |||
| congenital nystagmus | AHR | Ahr* | 1 model | Alliance of Genome Resources | |||
| optic atrophy | RPL24 | Rpl24* | 1 model | Alliance of Genome Resources | |||
| trigeminal neuralgia | GABRG1 | Gabrg1* | 1 model | Alliance of Genome Resources | |||
| | anterior ischemic optic neuropathy | CSF3* | Csf3 | Alliance of Genome Resources | |||
| anterior ischemic optic neuropathy | ND1* | mt-Nd1 | Alliance of Genome Resources | ||||
| anterior ischemic optic neuropathy | NOS3* | Nos3 | Alliance of Genome Resources | ||||
| autosomal recessive congenital nystagmus | ROBO1* | Robo1 | Alliance of Genome Resources | ||||
| bilateral optic nerve hypoplasia | PAX6* | Pax6 | Alliance of Genome Resources | ||||
| congenital fibrosis of the extraocular muscles 1 | KIF21A* | Kif21a | Alliance of Genome Resources | ||||
| congenital fibrosis of the extraocular muscles 2 | PHOX2A* | Phox2a | Alliance of Genome Resources | ||||
| congenital fibrosis of the extraocular muscles 3A | TUBB3* | Tubb3 | Alliance of Genome Resources | ||||
| congenital fibrosis of the extraocular muscles 5 | COL25A1* | Col25a1 | Alliance of Genome Resources | ||||
| congenital nystagmus | ROBO1* | Robo1 | Alliance of Genome Resources | ||||
| congenital nystagmus | PAX6* | Pax6 | Alliance of Genome Resources | ||||
| congenital nystagmus | MYO7A* | Myo7a | Alliance of Genome Resources | ||||
| congenital nystagmus 6 | GPR143* | Gpr143 | Alliance of Genome Resources | ||||
| Duane retraction syndrome | SALL4* | Sall4 | Alliance of Genome Resources | ||||
| Leber hereditary optic neuropathy | RPGRIP1* | Rpgrip1 | Alliance of Genome Resources | ||||
| Leber hereditary optic neuropathy | TP53* | Trp53 | Alliance of Genome Resources | ||||
| Leber hereditary optic neuropathy | ATP6* | Atp6-ps, mt-Atp6 | Alliance of Genome Resources | ||||
| Leber hereditary optic neuropathy | EPHX1* | Ephx1 | Alliance of Genome Resources | ||||
| Leber hereditary optic neuropathy | ND1* | mt-Nd1 | Alliance of Genome Resources | ||||
| Leber hereditary optic neuropathy | ND2* | mt-Nd2 | Alliance of Genome Resources | ||||
| Leber hereditary optic neuropathy | ND3* | mt-Nd3 | Alliance of Genome Resources | ||||
| Leber hereditary optic neuropathy | ND4* | mt-Nd4 | Alliance of Genome Resources | ||||
| Leber hereditary optic neuropathy | ND4L* | mt-Nd4l | Alliance of Genome Resources | ||||
| Leber hereditary optic neuropathy | ND5* | mt-Nd5 | Alliance of Genome Resources | ||||
| Leber hereditary optic neuropathy | PARL* | Parl | Alliance of Genome Resources | ||||
| Leber hereditary optic neuropathy | RDH12* | Rdh12 | Alliance of Genome Resources | ||||
| Leber hereditary optic neuropathy | SOD2* | Sod2 | Alliance of Genome Resources | ||||
| neuromyelitis optica | AQP4* | Aqp4 | Alliance of Genome Resources | ||||
| neuromyelitis optica | HLA-DRB1*, HLA-DRB3, HLA-DRB4, HLA-DRB5 | H2-Eb1, H2-Eb2 | Alliance of Genome Resources | ||||
| neuromyelitis optica | HLA-DQB1*, HLA-DQB2 | H2-Ab1 | Alliance of Genome Resources | ||||
| non-arteritic anterior ischemic optic neuropathy | ACE* | Ace | Alliance of Genome Resources | ||||
| non-arteritic anterior ischemic optic neuropathy | F5* | F5 | Alliance of Genome Resources | ||||
| non-arteritic anterior ischemic optic neuropathy | GP1BA* | Gp1ba | Alliance of Genome Resources | ||||
| non-arteritic anterior ischemic optic neuropathy | ITGB3* | Itgb3 | Alliance of Genome Resources | ||||
| non-arteritic anterior ischemic optic neuropathy | MTHFR* | Mthfr | Alliance of Genome Resources | ||||
| optic atrophy | WFS1* | Wfs1 | Alliance of Genome Resources | ||||
| optic atrophy | SSBP1* | Ssbp1 | Alliance of Genome Resources | ||||
| optic atrophy | MIEF1* | Mief1 | Alliance of Genome Resources | ||||
| optic atrophy | MECR* | Mecr | Alliance of Genome Resources | ||||
| optic atrophy | MCAT* | Mcat | Alliance of Genome Resources | ||||
| optic atrophy 1 | WFS1* | Wfs1 | Alliance of Genome Resources | ||||
| optic atrophy 1 | OPA1* | Opa1 | Alliance of Genome Resources | ||||
| optic atrophy 10 | RTN4IP1* | Rtn4ip1 | Alliance of Genome Resources | ||||
| optic atrophy 11 | YME1L1* | Yme1l1 | Alliance of Genome Resources | ||||
| optic atrophy 12 | AFG3L2* | Afg3l2 | Alliance of Genome Resources | ||||
| optic atrophy 3 | OPA3* | Opa3 | Alliance of Genome Resources | ||||
| optic atrophy 5 | DNM1L* | Dnm1l | Alliance of Genome Resources | ||||
| optic atrophy 7 | TMEM126A* | Tmem126a | Alliance of Genome Resources | ||||
| optic atrophy 9 | ACO2* | Aco2 | Alliance of Genome Resources | ||||
| optic nerve disease | EDN1* | Edn1 | Alliance of Genome Resources | ||||
| optic nerve glioma | NF1* | Nf1 | Alliance of Genome Resources | ||||
| optic neuritis | AQP4* | Aqp4 | Alliance of Genome Resources | ||||
| optic neuritis | HLA-DRB1*, HLA-DRB3, HLA-DRB4, HLA-DRB5 | H2-Eb1, H2-Eb2 | Alliance of Genome Resources | ||||
| optic neuritis | HLA-DQB1*, HLA-DQB2 | H2-Ab1 | Alliance of Genome Resources | ||||
| optic neuritis | GSTT1* | Gstt1 | Alliance of Genome Resources | ||||
| optic neuritis | MOG* | Mog | Alliance of Genome Resources | ||||
| optic neuritis | GSTM1*, GSTM5 | Gstm1, Gstm2, Gstm3, Gstm6 | Alliance of Genome Resources | ||||
| optic neuritis | CAT* | Cat | Alliance of Genome Resources | ||||
| optic neuritis | SOD2* | Sod2 | Alliance of Genome Resources | ||||
Excel File
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Transgenes and other genome features developed in mice to model this disease.
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| Disease Term | Transgenes and Other Genome Features | Mouse Models | |
| Leber hereditary optic neuropathy | Tg(LONP1-mt-ND4*,-mCherry*)#Jguy | 1 model | |