Disease Term | Human Homologs | Mouse Homologs | Mouse Models | Homology Source | |||
congestive heart failure | GNAQ* | Gnaq* | 2 models | Alliance of Genome Resources | |||
primary pulmonary hypertension | BMPR2* | Bmpr2* | 4 models | Alliance of Genome Resources | |||
primary pulmonary hypertension | SMAD9* | Smad9* | 1 model | Alliance of Genome Resources | |||
congestive heart failure | ACE2 | Ace2* | 1 model | Alliance of Genome Resources | |||
congestive heart failure | CALR | Calr* | 1 model | Alliance of Genome Resources | |||
congestive heart failure | CSRP3 | Csrp3* | 1 model | Alliance of Genome Resources | |||
congestive heart failure | CXCR4 | Cxcr4* | 1 model | Alliance of Genome Resources | |||
congestive heart failure | MED1 | Med1* | 2 models | Alliance of Genome Resources | |||
congestive heart failure | MTPN | Mtpn* | 1 model | Alliance of Genome Resources | |||
congestive heart failure | PPARGC1A | Ppargc1a* | 1 model | Alliance of Genome Resources | |||
congestive heart failure | SOD2 | Sod2* | 2 models | Alliance of Genome Resources | |||
congestive heart failure | TNF | Tnf* | 2 models | Alliance of Genome Resources | |||
primary pulmonary hypertension | ADORA2A | Adora2a* | 1 model | Alliance of Genome Resources | |||
primary pulmonary hypertension | PPARG | Pparg* | 1 model | Alliance of Genome Resources | |||
primary pulmonary hypertension | TNFSF4 | Tnfsf4* | 1 model | Alliance of Genome Resources | |||
primary pulmonary hypertension | VIP | Vip* | 1 model | Alliance of Genome Resources | |||
congestive heart failure | SLC6A4* | Slc6a4 | Alliance of Genome Resources | ||||
congestive heart failure | SLC9A1* | Slc9a1 | Alliance of Genome Resources | ||||
congestive heart failure | SMC1A* | Smc1a | Alliance of Genome Resources | ||||
congestive heart failure | SRSF2* | Srsf2 | Alliance of Genome Resources | ||||
congestive heart failure | TNFRSF1B* | Tnfrsf1b | Alliance of Genome Resources | ||||
congestive heart failure | YY1* | Yy1 | Alliance of Genome Resources | ||||
congestive heart failure | ADRA2C* | Adra2c | Alliance of Genome Resources | ||||
congestive heart failure | ADRB1* | Adrb1 | Alliance of Genome Resources | ||||
congestive heart failure | AGT* | Agt | Alliance of Genome Resources | ||||
congestive heart failure | AGXT2* | Agxt2 | Alliance of Genome Resources | ||||
congestive heart failure | AMPD1* | Ampd1 | Alliance of Genome Resources | ||||
congestive heart failure | APOE* | Apoe | Alliance of Genome Resources | ||||
congestive heart failure | CBL* | Cbl | Alliance of Genome Resources | ||||
congestive heart failure | CCR2* | Ccr2 | Alliance of Genome Resources | ||||
congestive heart failure | EDN1* | Edn1 | Alliance of Genome Resources | ||||
congestive heart failure | EP300* | Ep300 | Alliance of Genome Resources | ||||
congestive heart failure | EPO* | Epo | Alliance of Genome Resources | ||||
congestive heart failure | EYA4* | Eya4 | Alliance of Genome Resources | ||||
congestive heart failure | EZH2* | Ezh2 | Alliance of Genome Resources | ||||
congestive heart failure | GNB1* | Gnb1 | Alliance of Genome Resources | ||||
congestive heart failure | MMP1* | Mmp1a, Mmp1b | Alliance of Genome Resources | ||||
congestive heart failure | NISCH* | Nisch | Alliance of Genome Resources | ||||
congestive heart failure | PHF6* | Phf6 | Alliance of Genome Resources | ||||
congestive heart failure | PRKACA* | Prkaca | Alliance of Genome Resources | ||||
congestive heart failure | PRKAR2A* | Prkar2a | Alliance of Genome Resources | ||||
congestive heart failure | RYR1* | Ryr1 | Alliance of Genome Resources | ||||
Cor pulmonale | CX3CL1* | Cx3cl1 | Alliance of Genome Resources | ||||
diastolic heart failure | ACE* | Ace | Alliance of Genome Resources | ||||
primary pulmonary hypertension | PTGIS* | Ptgis | Alliance of Genome Resources | ||||
primary pulmonary hypertension | RYR1* | Ryr1 | Alliance of Genome Resources | ||||
primary pulmonary hypertension | ATP13A3* | Atp13a3 | Alliance of Genome Resources | ||||
primary pulmonary hypertension | CAV1* | Cav1 | Alliance of Genome Resources | ||||
primary pulmonary hypertension | KCNK3* | Kcnk3 | Alliance of Genome Resources | ||||
systolic heart failure | NPPB* | Nppb | Alliance of Genome Resources |
Transgenes and other genome features developed in mice to model this disease.
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Disease Term | Transgenes and Other Genome Features | Mouse Models | |
congestive heart failure | Tg(tetO-TPR/MET,-EGFP)12Tcre | 1 model | |
congestive heart failure | Tg(CAG-Calr)#Mlk | 1 model | |
congestive heart failure | Tg(Myh6-CACNA1C)M1Aschw | 1 model | |
congestive heart failure | Tg(Myh6-Camk2d_ic)#Jhb | 1 model | |
congestive heart failure | Tg(Myh6-Camk2d_ic)LJhb | 1 model | |
congestive heart failure | Tg(Myh6-Camk2d_ic)MJhb | 1 model | |
congestive heart failure | Tg(Myh6-cre)TG9Pjay | 1 model | |
congestive heart failure | Tg(Myh6-Gnaq)40Gwd | 1 model | |
congestive heart failure | Tg(Myh6-Gnaq*Q209L/Esr1*)7Rzl | 1 model | |
congestive heart failure | Tg(Myh6-HBEGF)#Iko | 1 model | |
congestive heart failure | Tg(Myh6-Mtpn)4Ssen | 1 model | |
congestive heart failure | Tg(Myh6-Tnf)1Brgi | 1 model | |
congestive heart failure | Tg(Myh6-Tnf)2Brgi | 1 model | |
congestive heart failure | Tg(tetO-Ppargc1a)1Dpk | 1 model | |
primary pulmonary hypertension | Tg(Lck-Tnfsf4)1Nish | 1 model | |
primary pulmonary hypertension | Tg(Scgb1a1-IL6)9Flv | 1 model | |
primary pulmonary hypertension | Tg(Tagln-SLC6A4)#Edd | 1 model | |
primary pulmonary hypertension | Tg(tetO-Bmpr2*R899X)#Jwst | 1 model | |
primary pulmonary hypertension | Tg(tetO-BMPR2*T504)1Jwst | 1 model |