Disease Term | Human Homologs | Mouse Homologs | Mouse Models | Homology Source | |||
achalasia | SPRY2 | Spry2* | 1 model | Alliance of Genome Resources | |||
achalasia | NOS1 | Nos1* | 1 model | Alliance of Genome Resources | |||
achalasia | LMNA | Lmna* | 2 models | Alliance of Genome Resources | |||
achalasia | VIPR1* | Vipr1 | Alliance of Genome Resources | ||||
achalasia | AAAS* | Aaas | Alliance of Genome Resources | ||||
achalasia | HLA-DQA1*, HLA-DQA2 | H2-Aa | Alliance of Genome Resources | ||||
achalasia | HLA-DQB1*, HLA-DQB2 | H2-Ab1 | Alliance of Genome Resources | ||||
Barrett's adenocarcinoma | GPX3* | Gpx3 | Alliance of Genome Resources | ||||
Barrett's adenocarcinoma | GPX7* | Gpx7 | Alliance of Genome Resources | ||||
Barrett's esophagus | MMP1* | Mmp1a, Mmp1b | Alliance of Genome Resources | ||||
Barrett's esophagus | GPX7* | Gpx7 | Alliance of Genome Resources | ||||
Barrett's esophagus | GPX3* | Gpx3 | Alliance of Genome Resources | ||||
Barrett's esophagus | FOXP1* | Foxp1 | Alliance of Genome Resources | ||||
Barrett's esophagus | CTHRC1* | Cthrc1 | Alliance of Genome Resources | ||||
Barrett's esophagus | B3GAT2* | B3gat2 | Alliance of Genome Resources | ||||
Barrett's esophagus | ASCC1* | Ascc1 | Alliance of Genome Resources | ||||
Barrett's esophagus | MSR1* | Msr1 | Alliance of Genome Resources | ||||
Barrett's esophagus | VDR* | Vdr | Alliance of Genome Resources | ||||
Barrett's esophagus | ZNF793* | ||||||
Barrett's esophagus | MMP12* | Mmp12 | Alliance of Genome Resources | ||||
eosinophilic esophagitis | ANKRD27* | Ankrd27 | Alliance of Genome Resources | ||||
eosinophilic esophagitis | CAPN14* | ||||||
eosinophilic esophagitis | CCL26* | Ccl26 | Alliance of Genome Resources | ||||
eosinophilic esophagitis | CYP2C19*, CYP2C8, CYP2C9, CYP2C18 | Cyp2c29, Cyp2c37, Cyp2c38, Cyp2c39, Cyp2c50, Cyp2c55, Cyp2c65, Cyp2c66 | Alliance of Genome Resources | ||||
eosinophilic esophagitis | TGFB1* | Tgfb1 | Alliance of Genome Resources | ||||
esophageal atresia | EFTUD2* | Eftud2 | Alliance of Genome Resources | ||||
esophageal atresia | GSTM1*, GSTM5 | Gstm1, Gstm2, Gstm3, Gstm6 | Alliance of Genome Resources | ||||
esophageal cancer | GSTM1*, GSTM5 | Gstm1, Gstm2, Gstm3, Gstm6 | Alliance of Genome Resources | ||||
esophageal cancer | GPX3* | Gpx3 | Alliance of Genome Resources | ||||
esophageal cancer | CYP1A1* | Cyp1a1 | Alliance of Genome Resources | ||||
esophageal cancer | XRCC1* | Xrcc1 | Alliance of Genome Resources | ||||
esophageal cancer | GSTT1* | Gstt1 | Alliance of Genome Resources | ||||
esophageal cancer | IL1R2* | Il1r2 | Alliance of Genome Resources | ||||
esophageal cancer | LZTS1* | Lzts1 | Alliance of Genome Resources | ||||
esophageal cancer | PTEN* | Pten | Alliance of Genome Resources | ||||
esophageal cancer | TNFAIP3* | Tnfaip3 | Alliance of Genome Resources | ||||
esophageal carcinoma | JAK2* | Jak2 | Alliance of Genome Resources | ||||
esophageal carcinoma | STAT3* | Stat3 | Alliance of Genome Resources | ||||
esophagitis | TNF* | Tnf | Alliance of Genome Resources | ||||
esophagitis | IL4R* | Il4ra | Alliance of Genome Resources | ||||
esophagitis | PTGS2* | Ptgs2 | Alliance of Genome Resources | ||||
esophagus adenocarcinoma | GPX3* | Gpx3 | Alliance of Genome Resources | ||||
esophagus adenocarcinoma | BCL2* | Bcl2 | Alliance of Genome Resources | ||||
esophagus adenocarcinoma | GHRL* | Ghrl | Alliance of Genome Resources | ||||
esophagus adenocarcinoma | FOXP1* | Foxp1 | Alliance of Genome Resources | ||||
esophagus adenocarcinoma | ERCC1* | Ercc1 | Alliance of Genome Resources | ||||
esophagus adenocarcinoma | CYP19A1* | Cyp19a1 | Alliance of Genome Resources | ||||
esophagus adenocarcinoma | TNFRSF10A*, TNFRSF10B, TNFRSF10C, TNFRSF10D | Tnfrsf10b | Alliance of Genome Resources | ||||
esophagus adenocarcinoma | CASP8* | Casp8 | Alliance of Genome Resources | ||||
esophagus adenocarcinoma | VDR* | Vdr | Alliance of Genome Resources | ||||
esophagus adenocarcinoma | BIRC3* | Birc3 | Alliance of Genome Resources | ||||
esophagus adenocarcinoma | ABL1* | Abl1 | Alliance of Genome Resources | ||||
esophagus adenocarcinoma | SLC22A18* | Slc22a18 | Alliance of Genome Resources | ||||
esophagus adenocarcinoma | NOS3* | Nos3 | Alliance of Genome Resources | ||||
esophagus adenocarcinoma | MMP14* | Mmp14 | Alliance of Genome Resources | ||||
esophagus adenocarcinoma | MMP12* | Mmp12 | Alliance of Genome Resources | ||||
esophagus adenocarcinoma | MMP1* | Mmp1a, Mmp1b | Alliance of Genome Resources | ||||
esophagus adenocarcinoma | MMP3* | Mmp3 | Alliance of Genome Resources | ||||
esophagus adenocarcinoma | KDR* | Kdr | Alliance of Genome Resources | ||||
esophagus adenocarcinoma | GSTT1* | Gstt1 | Alliance of Genome Resources | ||||
esophagus adenocarcinoma | GSTM1*, GSTM5 | Gstm1, Gstm2, Gstm3, Gstm6 | Alliance of Genome Resources | ||||
esophagus adenocarcinoma | GRB7* | Grb7 | Alliance of Genome Resources | ||||
esophagus squamous cell carcinoma | TET2* | Tet2 | Alliance of Genome Resources | ||||
esophagus squamous cell carcinoma | AZIN1* | Azin1 | Alliance of Genome Resources | ||||
esophagus squamous cell carcinoma | BRCA1* | Brca1 | Alliance of Genome Resources | ||||
esophagus squamous cell carcinoma | BRCA2* | Brca2 | Alliance of Genome Resources | ||||
esophagus squamous cell carcinoma | CALR* | Calr | Alliance of Genome Resources | ||||
esophagus squamous cell carcinoma | CDKN2B* | Cdkn2b | Alliance of Genome Resources | ||||
esophagus squamous cell carcinoma | CHRNA5* | Chrna5 | Alliance of Genome Resources | ||||
esophagus squamous cell carcinoma | CHRNA7*, CHRFAM7A | Chrna7 | Alliance of Genome Resources | ||||
esophagus squamous cell carcinoma | CLPTM1L* | Clptm1l | Alliance of Genome Resources | ||||
esophagus squamous cell carcinoma | COL14A1* | Col14a1 | Alliance of Genome Resources | ||||
esophagus squamous cell carcinoma | CYP1A1* | Cyp1a1 | Alliance of Genome Resources | ||||
esophagus squamous cell carcinoma | CYP24A1* | Cyp24a1 | Alliance of Genome Resources | ||||
esophagus squamous cell carcinoma | DCC* | Dcc | Alliance of Genome Resources | ||||
esophagus squamous cell carcinoma | EFNB2* | Efnb2 | Alliance of Genome Resources | ||||
esophagus squamous cell carcinoma | EPB41L3* | Epb41l3 | Alliance of Genome Resources | ||||
esophagus squamous cell carcinoma | ERBB4* | Erbb4 | Alliance of Genome Resources | ||||
esophagus squamous cell carcinoma | FANCA* | Fanca | Alliance of Genome Resources | ||||
esophagus squamous cell carcinoma | FAT1* | Fat1 | Alliance of Genome Resources | ||||
esophagus squamous cell carcinoma | FES* | Fes | Alliance of Genome Resources | ||||
esophagus squamous cell carcinoma | FGFR4* | Fgfr4 | Alliance of Genome Resources | ||||
esophagus squamous cell carcinoma | FOXA1* | Foxa1 | Alliance of Genome Resources | ||||
esophagus squamous cell carcinoma | GPX3* | Gpx3 | Alliance of Genome Resources | ||||
esophagus squamous cell carcinoma | GSTM1*, GSTM5 | Gstm1, Gstm2, Gstm3, Gstm6 | Alliance of Genome Resources | ||||
esophagus squamous cell carcinoma | GSTP1* | Gstp1, Gstp2, Gstp3, Gstp-ps | Alliance of Genome Resources | ||||
esophagus squamous cell carcinoma | GSTT1* | Gstt1 | Alliance of Genome Resources | ||||
esophagus squamous cell carcinoma | HTRA1* | Htra1 | Alliance of Genome Resources | ||||
esophagus squamous cell carcinoma | IDH2* | Idh2 | Alliance of Genome Resources | ||||
esophagus squamous cell carcinoma | KDM4C* | Kdm4c | Alliance of Genome Resources | ||||
esophagus squamous cell carcinoma | KDM6A* | Kdm6a | Alliance of Genome Resources | ||||
esophagus squamous cell carcinoma | KMT2C* | Kmt2c | Alliance of Genome Resources | ||||
esophagus squamous cell carcinoma | KMT2D* | Kmt2d | Alliance of Genome Resources | ||||
esophagus squamous cell carcinoma | LZTS1* | Lzts1 | Alliance of Genome Resources | ||||
esophagus squamous cell carcinoma | MAP3K1* | Map3k1 | Alliance of Genome Resources | ||||
esophagus squamous cell carcinoma | MBD4* | Mbd4 | Alliance of Genome Resources | ||||
esophagus squamous cell carcinoma | MGMT* | Mgmt | Alliance of Genome Resources | ||||
esophagus squamous cell carcinoma | MLH1* | Mlh1 | Alliance of Genome Resources | ||||
esophagus squamous cell carcinoma | MSH2* | Msh2 | Alliance of Genome Resources | ||||
esophagus squamous cell carcinoma | PTPRT* | Ptprt | Alliance of Genome Resources | ||||
esophagus squamous cell carcinoma | RICTOR* | Rictor | Alliance of Genome Resources | ||||
esophagus squamous cell carcinoma | RNF6* | Rnf6 | Alliance of Genome Resources | ||||
esophagus squamous cell carcinoma | RUNX1* | Runx1 | Alliance of Genome Resources | ||||
esophagus squamous cell carcinoma | SPEN* | Spen | Alliance of Genome Resources | ||||
esophagus squamous cell carcinoma | SULT1A1*, SULT1A2, SULT1A3, SULT1A4 | Sult1a1 | Alliance of Genome Resources | ||||
esophagus squamous cell carcinoma | TERT* | Tert | Alliance of Genome Resources | ||||
esophagus squamous cell carcinoma | TGFBR2* | Tgfbr2 | Alliance of Genome Resources | ||||
esophagus squamous cell carcinoma | TP53* | Trp53 | Alliance of Genome Resources | ||||
esophagus squamous cell carcinoma | WWOX* | Wwox | Alliance of Genome Resources | ||||
esophagus squamous cell carcinoma | XRCC1* | Xrcc1 | Alliance of Genome Resources | ||||
peptic esophagitis | VDR* | Vdr | Alliance of Genome Resources |
Transgenes and other genome features developed in mice to model this disease.
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Disease Term | Transgenes and Other Genome Features | Mouse Models | |
Barrett's esophagus | Tg(ED-L2-IL1RN/IL1B)#Tcw | 1 model | |
esophageal cancer | Tg(ED-L2-IL1RN/IL1B)#Tcw | 1 model |