| Disease Term | Human Homologs | Mouse Homologs | Mouse Models | Homology Source | |||
  | Creutzfeldt-Jakob disease | PRNP* | Prnp* | 8 models | Alliance of Genome Resources | ||
| fatal familial insomnia | PRNP* | Prnp* | 1 model | Alliance of Genome Resources | |||
| Gerstmann-Straussler-Scheinker syndrome | PRNP* | Prnp* | 7 models | Alliance of Genome Resources | |||
| | Creutzfeldt-Jakob disease | STX1A* | Stx1a | Alliance of Genome Resources | |||
| Creutzfeldt-Jakob disease | HLA-DQB1*, HLA-DQB2 | H2-Ab1 | Alliance of Genome Resources | ||||
| fatal familial insomnia | MIR146A* | Mir146 | Alliance of Genome Resources | ||||
| Huntington's disease-like 1 | PRNP* | Prnp | Alliance of Genome Resources | ||||
| kuru | PRNP* | Prnp | Alliance of Genome Resources | ||||
| prion disease | SOD1* | Sod1 | Alliance of Genome Resources | ||||
Excel File
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Transgenes and other genome features developed in mice to model this disease.
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| Disease Term | Transgenes and Other Genome Features | Mouse Models | |
| Creutzfeldt-Jakob disease | Tg(Prnp*D177N*M128V)A21Rchi | 4 models | |
| Creutzfeldt-Jakob disease | Tg(Prnp*)#Rgab | 2 models | |
| Gerstmann-Straussler-Scheinker syndrome | Tg(Prnp*P101L)174Sbp | 1 model | |
| Gerstmann-Straussler-Scheinker syndrome | Tg(Prnp*P101L)2866Sbp | 3 models | |
| Gerstmann-Straussler-Scheinker syndrome | Tg(Prnp*P101L)2862Sbp | 1 model | |
| Gerstmann-Straussler-Scheinker syndrome | Tg(Prnp*A116V*M128V)1309Jama | 1 model | |
| Gerstmann-Straussler-Scheinker syndrome | Tg(Prnp*P101L)2247Sbp | 1 model | |