| Disease Term | Human Homologs | Mouse Homologs | Mouse Models | Homology Source | |||
  | hepatocellular carcinoma | APC* | Apc* | 1 model | Alliance of Genome Resources | ||
| hepatocellular carcinoma | NR1H4* | Nr1h4* | 2 models | Alliance of Genome Resources | |||
| | hepatocellular carcinoma | ABCB4 | Abcb4* | 1 model | Alliance of Genome Resources | ||
| hepatocellular carcinoma | CDKN1A | Cdkn1a* | 4 models | Alliance of Genome Resources | |||
| hepatocellular carcinoma | FOXM1 | Foxm1* | 1 model | Alliance of Genome Resources | |||
| hepatocellular carcinoma | GNMT | Gnmt* | 1 model | Alliance of Genome Resources | |||
| hepatocellular carcinoma | IQGAP2 | Iqgap2* | 1 model | Alliance of Genome Resources | |||
| hepatocellular carcinoma | KRT18 | Krt18* | 1 model | Alliance of Genome Resources | |||
| hepatocellular carcinoma | MCM9 | Mcm9* | 3 models | Alliance of Genome Resources | |||
| hepatocellular carcinoma | MYC | Myc*, Bmyc | 8 models | Alliance of Genome Resources | |||
| hepatocellular carcinoma | NFE2L1 | Nfe2l1* | 1 model | Alliance of Genome Resources | |||
| hepatocellular carcinoma | PLAU | Plau* | 1 model | Alliance of Genome Resources | |||
| hepatocellular carcinoma | PTEN | Pten* | 3 models | Alliance of Genome Resources | |||
| hepatocellular carcinoma | SAV1 | Sav1* | 1 model | Alliance of Genome Resources | |||
| hepatocellular carcinoma | TXNIP | Txnip* | 3 models | Alliance of Genome Resources | |||
| hepatocellular carcinoma | UACA | Uaca* | 1 model | Alliance of Genome Resources | |||
| | fibrolamellar carcinoma | CTNNB1* | Ctnnb1 | Alliance of Genome Resources | |||
| fibrolamellar carcinoma | PRKACA* | Prkaca | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | ABCB1* | Abcb1a, Abcb1b | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | ACE* | Ace | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | ADIPOQ* | Adipoq | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | ALB* | Alb | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | ALDH2* | Aldh2 | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | ALX4* | Alx4 | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | APOC3* | Apoc3 | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | ARG1* | Arg1 | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | ARID1A* | Arid1a | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | ARID2* | Arid2 | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | ASS1* | Ass1 | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | AXIN1* | Axin1 | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | AZIN1* | Azin1 | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | BIRC3* | Birc3 | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | BMI1*, COMMD3-BMI1 | Bmi1 | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | CAB39* | Cab39 | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | CALR* | Calr | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | CASP8* | Casp8 | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | CAT* | Cat | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | CBX4* | Cbx4 | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | CCL2*, CCL13 | Ccl2, Ccl12 | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | CCL5* | Ccl5 | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | CCND1* | Ccnd1 | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | CCND2* | Ccnd2 | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | CCNG1* | Ccng1 | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | CDH1* | Cdh1 | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | CDK13* | Cdk13 | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | CDKN3* | Cdkn3 | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | CEP164* | Cep164 | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | CLPTM1L* | Clptm1l | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | CSF1R* | Csf1r | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | CTLA4* | Ctla4 | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | CTNNB1* | Ctnnb1 | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | CXCL8* | ||||||
| hepatocellular carcinoma | CYP2C19*, CYP2C8, CYP2C9, CYP2C18 | Cyp2c29, Cyp2c37, Cyp2c38, Cyp2c39, Cyp2c50, Cyp2c55, Cyp2c65, Cyp2c66 | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | CYP2E1* | Cyp2e1 | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | DICER1* | Dicer1 | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | EFTUD2* | Eftud2 | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | EGF* | Egf | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | ERBB4* | Erbb4 | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | ERCC2* | Ercc2 | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | ERN1* | Ern1 | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | EZH2* | Ezh2 | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | FES* | Fes | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | FGFR1* | Fgfr1 | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | FGFR2* | Fgfr2 | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | FLT3* | Flt3 | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | FOXA1* | Foxa1 | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | FUBP1* | Fubp1 | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | G6PC1* | G6pc1 | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | GC* | Gc | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | GPX1* | Gpx1 | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | GPX3* | Gpx3 | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | GSTM1*, GSTM5 | Gstm1, Gstm2, Gstm3, Gstm6 | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | GSTT1* | Gstt1 | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | HLA-DQA1*, HLA-DQA2 | H2-Aa | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | HLA-DQB1*, HLA-DQB2 | H2-Ab1 | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | HAMP* | Hamp, Hamp2 | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | HAVCR2* | Havcr2 | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | HFE* | Hfe | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | HILPDA* | Hilpda | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | HLA-DPA1* | ||||||
| hepatocellular carcinoma | HNF1A* | Hnf1a | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | HNRNPAB* | Hnrnpab | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | HNRNPL* | Hnrnpl | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | HRAS* | Hras | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | IER2* | Ier2 | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | IFNA1*, IFNA2*, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA21 | Ifna1, Ifna2, Ifna4, Ifna5, Ifna6, Ifna7, Ifna9, Ifna11, Ifna12, Ifna13, Ifna14, Ifna15, Ifna16, Ifnab | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | IFNL1*, IFNL2, IFNL3 | Ifnl2, Ifnl3 | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | IGF1R* | Igf1r | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | IGF2* | Igf2 | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | IGF2R* | Igf2r | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | IL1B* | Il1b | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | IL2* | Il2 | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | IL6* | Il6 | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | IL10* | Il10 | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | IL12A* | Il12a | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | IL18* | Il18 | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | IL21* | Il21 | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | JAK1* | Jak1 | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | KDM6A* | Kdm6a | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | KDR* | Kdr | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | KIF1B* | Kif1b | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | KIR3DS1*, KIR2DL1, KIR2DL2, KIR2DL3, KIR2DL4, KIR2DL5A, KIR2DL5B, KIR2DP1, KIR2DS1, KIR2DS2, KIR2DS3, KIR2DS4, KIR2DS5, KIR3DL1, KIR3DL2, KIR3DL3, KIR3DP1 | Kir3dl1, Kir3dl2 | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | KLF4* | Klf4 | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | KMT2B* | Kmt2b | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | LECT2* | Lect2 | 1 model | Alliance of Genome Resources | |||
| hepatocellular carcinoma | LEP* | Lep | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | LEPR* | Lepr | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | LRP1B* | Lrp1b | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | LZTR1* | Lztr1 | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | MAP4K4* | Map4k4 | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | MBL2* | Mbl2 | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | MCM7* | Mcm7 | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | MDM2* | Mdm2 | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | MET* | Met | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | MIR23B* | Mir23b | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | MIR27A* | Mir27a | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | MIR34A* | Mir34a | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | MIR122* | Mir122 | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | MIR133A1* | Mir133a-1 | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | MIR146A* | Mir146 | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | MIR155* | Mir155 | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | MIR193A* | Mir193a | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | MIR195* | Mir195a | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | MIR196A2* | Mir196a-2 | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | MIR200B* | Mir200b | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | MIR212* | Mir212 | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | MIR221* | Mir221 | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | MIR302D* | Mir302d | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | MIR432* | Mir432 | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | MIR665* | Mir665 | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | MIR766* | ||||||
| hepatocellular carcinoma | MPO* | Mpo | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | MTDH* | Mtdh | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | MTHFR* | Mthfr | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | MTRR* | Mtrr | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | MYD88* | Myd88 | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | NF2* | Nf2 | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | NFE2L2* | Nfe2l2 | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | NFKB1* | Nfkb1 | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | NFKBIA* | Nfkbia | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | NKX3-1* | Nkx3-1 | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | NRAS* | Nras | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | PDCD1* | Pdcd1 | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | PDGFRL* | Pdgfrl | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | PIK3CA* | Pik3ca | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | PINX1* | Pinx1 | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | PLCG1* | Plcg1 | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | PNPLA3* | Pnpla3 | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | POLG* | Polg | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | POT1* | Pot1a, Pot1b | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | PPARA* | Ppara | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | PRDM1* | Prdm1 | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | PTGS2* | Ptgs2 | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | PTPN13* | Ptpn13 | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | PVT1* | Pvt1 | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | RAD21* | Rad21 | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | RAD52* | Rad52 | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | RECQL* | Recql | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | RIT1* | Rit1 | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | RNF43* | Rnf43 | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | RYR3* | Ryr3 | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | SF3B1* | Sf3b1 | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | SF3B4* | Sf3b4 | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | SLC7A5* | Slc7a5 | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | SLC38A1* | Slc38a1 | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | SMARCA4* | Smarca4 | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | SMC3* | Smc3 | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | SMO* | Smo | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | SNRPE* | Snrpe, Snrpert | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | SOAT2* | Soat2 | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | SOCS1* | Socs1 | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | SOD2* | Sod2 | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | SOX30* | Sox30 | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | SPAG9* | Spag9 | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | SPOCK1* | Spock1 | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | SPOP* | Spop | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | SPP1* | Spp1 | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | SRSF2* | Srsf2 | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | STAT4* | Stat4 | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | TEP1* | Tep1 | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | TERT* | Tert | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | TET2* | Tet2 | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | TLR2* | Tlr2 | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | TLR4* | Tlr4 | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | TLR9* | Tlr9 | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | TNF* | Tnf | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | TRAF7* | Traf7 | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | TP53* | Trp53 | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | TYMS* | Tyms | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | VDR* | Vdr | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | VEGFA* | Vegfa | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | WNT2* | Wnt2 | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | XPO1* | Xpo1 | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | XPO5* | Xpo5 | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | XRCC1* | Xrcc1 | Alliance of Genome Resources | ||||
| hepatocellular carcinoma | ZFHX3* | Zfhx3 | Alliance of Genome Resources | ||||
| hepatocellular clear cell carcinoma | IDH2* | Idh2 | Alliance of Genome Resources | ||||
| hepatocellular clear cell carcinoma | IDH1* | Idh1 | Alliance of Genome Resources | ||||
Excel File
|
Transgenes and other genome features developed in mice to model this disease.
|
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| Disease Term | Transgenes and Other Genome Features | Mouse Models | |
| hepatocellular carcinoma | Tg(Alb1HBV)44Bri | 1 model | |
| hepatocellular carcinoma | Tg(Alb-E2F1)8Sst | 2 models | |
| hepatocellular carcinoma | Tg(Alb-HBx)A112Tfts | 1 model | |
| hepatocellular carcinoma | Tg(Alb-HRAS*G12V)28Yu | 1 model | |
| hepatocellular carcinoma | Tg(Alb-PDGFC)#Jcam | 1 model | |
| hepatocellular carcinoma | Tg(Alb-SND1)3aDsar | 1 model | |
| hepatocellular carcinoma | Tg(Alb-TAg)1Gjh | 1 model | |
| hepatocellular carcinoma | Tg(Alb-TAg)#Arnd | 1 model | |
| hepatocellular carcinoma | Tg(HBV-HCV)Kko | 1 model | |
| hepatocellular carcinoma | Tg(HBVX*,-Myc)#Skp | 1 model | |
| hepatocellular carcinoma | Tg(HBx)3Yu | 1 model | |
| hepatocellular carcinoma | Tg(Mup3-Plau)350-2Eps | 1 model | |
| hepatocellular carcinoma | Tg(Myl2-FGF19)1Dfre | 1 model | |
| hepatocellular carcinoma | Tg(Pklr-Myc)73Ak | 4 models | |
| hepatocellular carcinoma | Tg(SERPINA1-TAg)1812Jtsb | 1 model | |
| hepatocellular carcinoma | Tg(SERPINC1-SV40)A1Pbr | 2 models | |
| hepatocellular carcinoma | Tg(SERPINC1-SV40)BPbr | 1 model | |
| hepatocellular carcinoma | Tg(tetO-MET)23Rwng | 1 model | |
| hepatocellular carcinoma | Tg(tetO-MYC)36aBop | 2 models | |
| hepatocellular carcinoma | Tg(tetO-MYC,-OVAL)#Gtgm | 1 model | |