| Disease Term | Human Homologs | Mouse Homologs | Mouse Models | Homology Source | |||
  | B-cell lymphoma | EZH2* | Ezh2* | 1 model | Alliance of Genome Resources | ||
| Burkitt lymphoma | MYC* | Myc*, Bmyc | 4 models | Alliance of Genome Resources | |||
| familial hemophagocytic lymphohistiocytosis 2 | PRF1* | Prf1* | 1 model | Alliance of Genome Resources | |||
| familial hemophagocytic lymphohistiocytosis 3 | UNC13D* | Unc13d* | 1 model | Alliance of Genome Resources | |||
| familial hemophagocytic lymphohistiocytosis 4 | STX11* | Stx11* | 1 model | Alliance of Genome Resources | |||
| | central conducting lymphatic anomaly | MDFIC | Mdfic* | 1 model | Alliance of Genome Resources | ||
| diffuse large B-cell lymphoma | SMURF2 | Smurf2* | 1 model | Alliance of Genome Resources | |||
| diffuse large B-cell lymphoma | TP53 | Trp53* | 2 models | Alliance of Genome Resources | |||
| follicular lymphoma | RARRES1 | Rarres1* | 3 models | Alliance of Genome Resources | |||
| hemophagocytic lymphohistiocytosis | ELP1 | Elp1* | 1 model | Alliance of Genome Resources | |||
| hemophagocytic lymphohistiocytosis | RAB27A | Rab27a* | 1 model | Alliance of Genome Resources | |||
| hereditary lymphedema | VEGFC | Vegfc* | 1 model | Alliance of Genome Resources | |||
| hereditary lymphedema | FLT4 | Flt4* | 1 model | Alliance of Genome Resources | |||
| Langerhans-cell histiocytosis | BRAF | Braf* | 2 models | Alliance of Genome Resources | |||
| lymphatic system disease | LGMN | Lgmn* | 1 model | Alliance of Genome Resources | |||
| lymphoma | MIR155 | Mir155* | 1 model | Alliance of Genome Resources | |||
| lymphoma | HMGA1 | Hmga1*, Hmga1b | 1 model | Alliance of Genome Resources | |||
| malignant histiocytic disease | RCBTB2 | Rcbtb2* | 2 models | Alliance of Genome Resources | |||
| non-Hodgkin lymphoma | S1PR2 | S1pr2* | 2 models | Alliance of Genome Resources | |||
| non-Hodgkin lymphoma | MTSS1 | Mtss1* | 1 model | Alliance of Genome Resources | |||
| peripheral T-cell lymphoma | RC3H1 | Rc3h1* | 1 model | Alliance of Genome Resources | |||
| T-cell acute lymphoblastic leukemia | HMGA1 | Hmga1*, Hmga1b | 1 model | Alliance of Genome Resources | |||
| T-cell acute lymphoblastic leukemia | NBN | Nbn* | 1 model | Alliance of Genome Resources | |||
| T-cell adult acute lymphocytic leukemia | CNTN2 | Cntn2* | 1 model | Alliance of Genome Resources | |||
| T-cell adult acute lymphocytic leukemia | ZEB2 | Zeb2* | 2 models | Alliance of Genome Resources | |||
| | acute biphenotypic leukemia | DOT1L* | Dot1l | Alliance of Genome Resources | |||
| adenoid cystic carcinoma | ATR* | Atr | Alliance of Genome Resources | ||||
| adenoid cystic carcinoma | KMT2C* | Kmt2c | Alliance of Genome Resources | ||||
| adenoid cystic carcinoma | XRN2* | Xrn2 | Alliance of Genome Resources | ||||
| adenoid cystic carcinoma | NTRK3* | Ntrk3 | Alliance of Genome Resources | ||||
| adenoid cystic carcinoma | KDM6A* | Kdm6a | Alliance of Genome Resources | ||||
| adult T-cell leukemia/lymphoma | FAS* | Fas | Alliance of Genome Resources | ||||
| adult T-cell leukemia/lymphoma | JAK3* | Jak3 | Alliance of Genome Resources | ||||
| adult T-cell leukemia/lymphoma | NOTCH1* | Notch1 | Alliance of Genome Resources | ||||
| adult T-cell leukemia/lymphoma | TAL2* | Tal2 | Alliance of Genome Resources | ||||
| adult T-cell leukemia/lymphoma | TLX1* | Tlx1 | Alliance of Genome Resources | ||||
| anaplastic large cell lymphoma | IRF4* | Irf4 | Alliance of Genome Resources | ||||
| B-cell lymphoma | ABCG2* | Abcg2, Abcg3 | Alliance of Genome Resources | ||||
| B-cell lymphoma | BRD2* | Brd2 | Alliance of Genome Resources | ||||
| B-cell lymphoma | BCL6* | Bcl6 | Alliance of Genome Resources | ||||
| B-cell lymphoma | IL21R* | Il21r | Alliance of Genome Resources | ||||
| B-cell lymphoma | BTK* | Btk | Alliance of Genome Resources | ||||
| B-cell lymphoma | CD40* | Cd40 | Alliance of Genome Resources | ||||
| B-lymphoblastic leukemia/lymphoma | F3* | F3 | Alliance of Genome Resources | ||||
| B-lymphoblastic leukemia/lymphoma | ABL1* | Abl1 | Alliance of Genome Resources | ||||
| B-lymphoblastic leukemia/lymphoma | TP53* | Trp53 | Alliance of Genome Resources | ||||
| B-lymphoblastic leukemia/lymphoma | TNFSF13* | Tnfsf13 | Alliance of Genome Resources | ||||
| B-lymphoblastic leukemia/lymphoma | TFPI* | Tfpi | Alliance of Genome Resources | ||||
| B-lymphoblastic leukemia/lymphoma | IKZF1* | Ikzf1 | Alliance of Genome Resources | ||||
| B-lymphoblastic leukemia/lymphoma | AKR1C3*, AKR1C1, AKR1C2, AKR1C4 | Akr1c6, Akr1c12, Akr1c13, Akr1c14, Akr1c18, Akr1c19, Akr1c20, Akr1c21, Akr1cl | Alliance of Genome Resources | ||||
| B-lymphoblastic leukemia/lymphoma | BRD2* | Brd2 | Alliance of Genome Resources | ||||
| B-lymphoblastic leukemia/lymphoma | CDKN2A* | Cdkn2a | Alliance of Genome Resources | ||||
| B-lymphoblastic leukemia/lymphoma | CYP3A5*, CYP3A4, CYP3A7, CYP3A7-CYP3A51P, CYP3A43 | Cyp3a11, Cyp3a13, Cyp3a16, Cyp3a25, Cyp3a41a, Cyp3a41b, Cyp3a44, Cyp3a57, Cyp3a59 | Alliance of Genome Resources | ||||
| Burkitt lymphoma | BTK* | Btk | Alliance of Genome Resources | ||||
| Burkitt lymphoma | CALR* | Calr | Alliance of Genome Resources | ||||
| Burkitt lymphoma | CD79B* | Cd79b | Alliance of Genome Resources | ||||
| Burkitt lymphoma | CD40* | Cd40 | Alliance of Genome Resources | ||||
| central conducting lymphatic anomaly | EPHB4* | Ephb4 | Alliance of Genome Resources | ||||
| central nervous system lymphoma | BTK* | Btk | Alliance of Genome Resources | ||||
| central nervous system lymphoma | MYD88* | Myd88 | Alliance of Genome Resources | ||||
| central nervous system lymphoma | IL10* | Il10 | Alliance of Genome Resources | ||||
| central nervous system lymphoma | CD79B* | Cd79b | Alliance of Genome Resources | ||||
| chronic lymphocytic leukemia | PON1* | Pon1 | Alliance of Genome Resources | ||||
| chronic lymphocytic leukemia | IRF4* | Irf4 | Alliance of Genome Resources | ||||
| chronic lymphocytic leukemia | PTPN22* | Ptpn22 | Alliance of Genome Resources | ||||
| chronic lymphocytic leukemia | CD79B* | Cd79b | Alliance of Genome Resources | ||||
| chronic lymphocytic leukemia | CD86* | Cd86 | Alliance of Genome Resources | ||||
| diffuse large B-cell lymphoma | CD40* | Cd40 | Alliance of Genome Resources | ||||
| diffuse large B-cell lymphoma | BCL6* | Bcl6 | Alliance of Genome Resources | ||||
| diffuse large B-cell lymphoma | CARD11* | Card11 | Alliance of Genome Resources | ||||
| diffuse large B-cell lymphoma | MYD88* | Myd88 | Alliance of Genome Resources | ||||
| diffuse large B-cell lymphoma | MTHFR* | Mthfr | Alliance of Genome Resources | ||||
| diffuse large B-cell lymphoma | IL21R* | Il21r | Alliance of Genome Resources | ||||
| diffuse large B-cell lymphoma | GSTT1* | Gstt1 | Alliance of Genome Resources | ||||
| diffuse large B-cell lymphoma | GSTP1* | Gstp1, Gstp2, Gstp3, Gstp-ps | Alliance of Genome Resources | ||||
| diffuse large B-cell lymphoma | CD22* | Cd22 | Alliance of Genome Resources | ||||
| diffuse large B-cell lymphoma | GSTM1*, GSTM5 | Gstm1, Gstm2, Gstm3, Gstm6 | Alliance of Genome Resources | ||||
| diffuse large B-cell lymphoma | FCGR2A*, FCGR2B, FCGR2C | Fcgr2b, Fcgr3 | Alliance of Genome Resources | ||||
| diffuse large B-cell lymphoma | CD79B* | Cd79b | Alliance of Genome Resources | ||||
| extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue | BIRC3* | Birc3 | Alliance of Genome Resources | ||||
| extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue | BCL10* | Bcl10 | Alliance of Genome Resources | ||||
| extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue | HLA-DQA1*, HLA-DQA2 | H2-Aa | Alliance of Genome Resources | ||||
| familial hemophagocytic lymphohistiocytosis 5 | STXBP2* | Stxbp2 | Alliance of Genome Resources | ||||
| follicular lymphoma | CD79B* | Cd79b | Alliance of Genome Resources | ||||
| follicular lymphoma | BCL2* | Bcl2 | Alliance of Genome Resources | ||||
| follicular lymphoma | CD40* | Cd40 | Alliance of Genome Resources | ||||
| follicular lymphoma | CD40LG* | Cd40lg | Alliance of Genome Resources | ||||
| follicular lymphoma | KDSR* | Kdsr | Alliance of Genome Resources | ||||
| hairy cell leukemia | GPX1* | Gpx1 | Alliance of Genome Resources | ||||
| Hennekam syndrome | CCBE1* | Ccbe1 | Alliance of Genome Resources | ||||
| Hennekam syndrome | FAT4* | Fat4 | Alliance of Genome Resources | ||||
| Hennekam syndrome | ADAMTS3* | Adamts3 | Alliance of Genome Resources | ||||
| hereditary lymphedema | TIE1* | Tie1 | Alliance of Genome Resources | ||||
| hereditary lymphedema | THSD1* | Thsd1 | Alliance of Genome Resources | ||||
| hereditary lymphedema | PIEZO1* | Piezo1 | Alliance of Genome Resources | ||||
| hereditary lymphedema | MDFIC* | Mdfic | Alliance of Genome Resources | ||||
| hereditary lymphedema | ERG* | Erg | Alliance of Genome Resources | ||||
| hereditary lymphedema | CELSR1* | Celsr1 | Alliance of Genome Resources | ||||
| hereditary lymphedema | CALCRL* | Calcrl | Alliance of Genome Resources | ||||
| hereditary lymphedema | ANGPT2* | Angpt2 | Alliance of Genome Resources | ||||
| hereditary lymphedema IA | FLT4* | Flt4 | Alliance of Genome Resources | ||||
| hereditary lymphedema IC | GJC2* | Gjc2 | Alliance of Genome Resources | ||||
| hereditary lymphedema ID | VEGFC* | Vegfc | Alliance of Genome Resources | ||||
| Hodgkin's lymphoma | GSTT1* | Gstt1 | Alliance of Genome Resources | ||||
| Hodgkin's lymphoma | KLHDC8B* | Klhdc8b | Alliance of Genome Resources | ||||
| Hodgkin's lymphoma | GSTM1*, GSTM5 | Gstm1, Gstm2, Gstm3, Gstm6 | Alliance of Genome Resources | ||||
| Hodgkin's lymphoma | NFKBIA* | Nfkbia | Alliance of Genome Resources | ||||
| Hodgkin's lymphoma | IL6* | Il6 | Alliance of Genome Resources | ||||
| Kawasaki disease | CD40LG* | Cd40lg | Alliance of Genome Resources | ||||
| Kawasaki disease | CD40* | Cd40 | Alliance of Genome Resources | ||||
| Kawasaki disease | CCR5* | Ccr5 | Alliance of Genome Resources | ||||
| Kawasaki disease | CCR2* | Ccr2 | Alliance of Genome Resources | ||||
| Kawasaki disease | VEGFA* | Vegfa | Alliance of Genome Resources | ||||
| Kawasaki disease | BTNL2* | Btnl2 | Alliance of Genome Resources | ||||
| Kawasaki disease | TNF* | Tnf | Alliance of Genome Resources | ||||
| Kawasaki disease | MBL2* | Mbl2 | Alliance of Genome Resources | ||||
| Kawasaki disease | IL18* | Il18 | Alliance of Genome Resources | ||||
| Kawasaki disease | HSPA1L* | Hspa1l | Alliance of Genome Resources | ||||
| Kawasaki disease | HSPA1A*, HSPA1B | Hspa1a, Hspa1b | Alliance of Genome Resources | ||||
| Kawasaki disease | CRP* | Crp | Alliance of Genome Resources | ||||
| lymphedema | GJC2* | Gjc2 | Alliance of Genome Resources | ||||
| lymphedema | FOXC2* | Foxc2 | Alliance of Genome Resources | ||||
| lymphoma | MALT1* | Malt1 | Alliance of Genome Resources | ||||
| lymphoma | PAFAH1B2* | Pafah1b2 | Alliance of Genome Resources | ||||
| lymphoma | PSMB9* | Psmb9 | Alliance of Genome Resources | ||||
| lymphoma | RELA* | Rela | Alliance of Genome Resources | ||||
| lymphoma | CHD4* | Chd4 | Alliance of Genome Resources | ||||
| lymphoma | MAD1L1* | Mad1l1 | Alliance of Genome Resources | ||||
| lymphoplasmacytic lymphoma | FCGR3A*, FCGR3B | Fcgr4 | Alliance of Genome Resources | ||||
| lymphoplasmacytic lymphoma | CXCR4* | Cxcr4 | Alliance of Genome Resources | ||||
| lymphoplasmacytic lymphoma | IL6* | Il6 | Alliance of Genome Resources | ||||
| lymphoplasmacytic lymphoma | IL10* | Il10 | Alliance of Genome Resources | ||||
| lymphoplasmacytic lymphoma | MYD88* | Myd88 | Alliance of Genome Resources | ||||
| mantle cell lymphoma | CCDC50* | Ccdc50 | Alliance of Genome Resources | ||||
| mantle cell lymphoma | BTK* | Btk | Alliance of Genome Resources | ||||
| mantle cell lymphoma | TNFRSF10A*, TNFRSF10B, TNFRSF10C, TNFRSF10D | Tnfrsf10b | Alliance of Genome Resources | ||||
| mantle cell lymphoma | CD79B* | Cd79b | Alliance of Genome Resources | ||||
| marginal zone lymphoma | HLA-DQA1*, HLA-DQA2 | H2-Aa | Alliance of Genome Resources | ||||
| marginal zone lymphoma | HLA-DQB1*, HLA-DQB2 | H2-Ab1 | Alliance of Genome Resources | ||||
| mature T-cell and NK-cell lymphoma | H19* | ||||||
| mycosis fungoides | HLA-DQB1*, HLA-DQB2 | H2-Ab1 | Alliance of Genome Resources | ||||
| nasal type extranodal NK/T-cell lymphoma | FAS* | Fas | Alliance of Genome Resources | ||||
| non-Hodgkin lymphoma | BCL10* | Bcl10 | Alliance of Genome Resources | ||||
| non-Hodgkin lymphoma | CTLA4* | Ctla4 | Alliance of Genome Resources | ||||
| non-Hodgkin lymphoma | CD79B* | Cd79b | Alliance of Genome Resources | ||||
| non-Hodgkin lymphoma | FCGR2A*, FCGR2B, FCGR2C | Fcgr2b, Fcgr3 | Alliance of Genome Resources | ||||
| non-Hodgkin lymphoma | CD40* | Cd40 | Alliance of Genome Resources | ||||
| non-Hodgkin lymphoma | CCND1* | Ccnd1 | Alliance of Genome Resources | ||||
| non-Hodgkin lymphoma | CASP10* | ||||||
| non-Hodgkin lymphoma | GPX1* | Gpx1 | Alliance of Genome Resources | ||||
| non-Hodgkin lymphoma | KMT2A* | Kmt2a | Alliance of Genome Resources | ||||
| non-Hodgkin lymphoma | MALT1* | Malt1 | Alliance of Genome Resources | ||||
| non-Hodgkin lymphoma | MTRR* | Mtrr | Alliance of Genome Resources | ||||
| non-Hodgkin lymphoma | PON1* | Pon1 | Alliance of Genome Resources | ||||
| non-Hodgkin lymphoma | PRF1* | Prf1 | Alliance of Genome Resources | ||||
| non-Hodgkin lymphoma | RAD54B* | Rad54b | Alliance of Genome Resources | ||||
| non-Hodgkin lymphoma | RAD54L* | Rad54l | Alliance of Genome Resources | ||||
| non-Hodgkin lymphoma | TMEM260* | Tmem260 | Alliance of Genome Resources | ||||
| non-Hodgkin lymphoma | EPHX1* | Ephx1 | Alliance of Genome Resources | ||||
| non-Langerhans-cell histiocytosis | RAB27A* | Rab27a | Alliance of Genome Resources | ||||
| non-Langerhans-cell histiocytosis | PRF1* | Prf1 | Alliance of Genome Resources | ||||
| peripheral T-cell lymphoma | IRF4* | Irf4 | Alliance of Genome Resources | ||||
| plasma cell leukemia | CD40* | Cd40 | Alliance of Genome Resources | ||||
| plasmacytoma | BCL2* | Bcl2 | Alliance of Genome Resources | ||||
| plasmacytoma | ROBO1* | Robo1 | Alliance of Genome Resources | ||||
| primary cutaneous T-cell non-Hodgkin lymphoma | CDKN2B* | Cdkn2b | Alliance of Genome Resources | ||||
| primary cutaneous T-cell non-Hodgkin lymphoma | CDKN2A* | Cdkn2a | Alliance of Genome Resources | ||||
| T-cell acute lymphoblastic leukemia | NUP98* | Nup98 | Alliance of Genome Resources | ||||
| T-cell acute lymphoblastic leukemia | RPL11* | Rpl11 | Alliance of Genome Resources | ||||
| T-cell acute lymphoblastic leukemia | LYL1* | Lyl1 | Alliance of Genome Resources | ||||
| T-cell acute lymphoblastic leukemia | JAK3* | Jak3 | Alliance of Genome Resources | ||||
| T-cell acute lymphoblastic leukemia | JAK1* | Jak1 | Alliance of Genome Resources | ||||
| T-cell acute lymphoblastic leukemia | DNMT3A* | Dnmt3a | Alliance of Genome Resources | ||||
| T-cell acute lymphoblastic leukemia | CXCR4* | Cxcr4 | Alliance of Genome Resources | ||||
| T-cell acute lymphoblastic leukemia | CDKN2A* | Cdkn2a | Alliance of Genome Resources | ||||
| T-cell acute lymphoblastic leukemia | AKR1C3*, AKR1C1, AKR1C2, AKR1C4 | Akr1c6, Akr1c12, Akr1c13, Akr1c14, Akr1c18, Akr1c19, Akr1c20, Akr1c21, Akr1cl | Alliance of Genome Resources | ||||
| T-cell acute lymphoblastic leukemia | RPL5* | Rpl5 | Alliance of Genome Resources | ||||
| T-cell acute lymphoblastic leukemia | PDGFRA* | Pdgfra | Alliance of Genome Resources | ||||
| T-cell non-Hodgkin lymphoma | TMEM260* | Tmem260 | Alliance of Genome Resources | ||||
| T-cell non-Hodgkin lymphoma | FGFR1* | Fgfr1 | Alliance of Genome Resources | ||||
| T-cell non-Hodgkin lymphoma | IER3* | Ier3 | Alliance of Genome Resources | ||||
| T-cell non-Hodgkin lymphoma | JAK3* | Jak3 | Alliance of Genome Resources | ||||
| T-cell prolymphocytic leukemia | JAK3* | Jak3 | Alliance of Genome Resources | ||||
| testicular lymphoma | MYD88* | Myd88 | Alliance of Genome Resources | ||||
| thymoma | DNMT3B* | Dnmt3b | Alliance of Genome Resources | ||||
| visceral leishmaniasis | CXCL8* | ||||||
| visceral leishmaniasis | IL32* | ||||||
| visceral leishmaniasis | LTA* | Lta | Alliance of Genome Resources | ||||
| visceral leishmaniasis | MBL2* | Mbl2 | Alliance of Genome Resources | ||||
| visceral leishmaniasis | SLC11A1* | Slc11a1 | Alliance of Genome Resources | ||||
| visceral leishmaniasis | HLA-DQA1*, HLA-DQA2 | H2-Aa | Alliance of Genome Resources | ||||
| visceral leishmaniasis | TNF* | Tnf | Alliance of Genome Resources | ||||
| visceral leishmaniasis | IL2RB* | Il2rb | Alliance of Genome Resources | ||||
| visceral leishmaniasis | CSF2* | Csf2 | Alliance of Genome Resources | ||||
Excel File
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Transgenes and other genome features developed in mice to model this disease.
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| Disease Term | Transgenes and Other Genome Features | Mouse Models | |
| Burkitt lymphoma | Tg(IGL-MYC)3Hm | 1 model | |
| Burkitt lymphoma | Tg(IghMyc)22Bri | 1 model | |
| chronic lymphocytic leukemia | Tg(Lck-TNFSF13)3919Mhah | 1 model | |
| chronic lymphocytic leukemia | Tg(Igh-V186.2-TCL1A)3Cro | 4 models | |
| chronic lymphocytic leukemia | Tg(Igh-TCL1A)1Ypek | 1 model | |
| chronic lymphocytic leukemia | Tg(Igh-ROR1)1Kip | 2 models | |
| chronic lymphocytic leukemia | Tg(Igh-Mir29a,-Mir29b-1,-hrGFP)#Cro | 2 models | |
| chronic lymphocytic leukemia | Mirc30 | 6 models | |
| chronic lymphocytic leukemia | Del(14Trim13-Rnaseh2b)6Rdf | 2 models | |
| chronic lymphocytic leukemia | Del(14Trim13-Dleu2)4Rdf | 2 models | |
| extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue | Tg(Ly6e-MALT1)#Isg | 1 model | |
| follicular lymphoma | Tg(Vav-BCL2)69Jad | 1 model | |
| hereditary lymphedema | Del(8A4-B3)7H | 1 model | |
| lymphoma | Tg(Vav1-STAT5B*N642H)726Biat | 1 model | |
| lymphoma | Tg(H2-K-Hmga1)#Lmsr | 1 model | |
| non-Hodgkin lymphoma | Tg(EmuSR-HDAC9)1468Kpet | 1 model | |
| non-Hodgkin lymphoma | Tg(tetO-NPM1/ALK,-luc)2Gde | 1 model | |
| non-Hodgkin lymphoma | Tg(tetO-TPM3/ALK,-luc)2Gde | 1 model | |
| plasmacytoma | Tg(H2-L-IL6)46Kish | 1 model | |
| T-cell acute lymphoblastic leukemia | Tg(H2-K-Hmga1)#Lmsr | 1 model | |
| T-cell adult acute lymphocytic leukemia | Tg(Lck-Tax)53Hall | 1 model | |