| Disease Term | Human Homologs | Mouse Homologs | Mouse Models | Homology Source | |||
  | hereditary neutrophilia | CSF3R* | Csf3r* | 1 model | Alliance of Genome Resources | ||
| leukocyte adhesion deficiency 1 | ITGB2* | Itgb2*, Itgb2l | 3 models | Alliance of Genome Resources | |||
| leukocyte adhesion deficiency 3 | FERMT3* | Fermt3* | 1 model | Alliance of Genome Resources | |||
| mastocytosis | KIT* | Kit* | 5 models | Alliance of Genome Resources | |||
| | leukocyte adhesion deficiency 3 | RASGRP2 | Rasgrp2* | 1 model | Alliance of Genome Resources | ||
| leukopenia | NUDT15 | Nudt15* | 2 models | Alliance of Genome Resources | |||
| multiple myeloma | MAF | Maf* | 2 models | Alliance of Genome Resources | |||
| neutropenia | NUDT15 | Nudt15* | 2 models | Alliance of Genome Resources | |||
| severe congenital neutropenia | GFI1 | Gfi1* | 1 model | Alliance of Genome Resources | |||
| | agranulocytosis | HLA-DQB1*, HLA-DQB2 | H2-Ab1 | Alliance of Genome Resources | |||
| agranulocytosis | NQO2* | Nqo2 | Alliance of Genome Resources | ||||
| agranulocytosis | IL1B* | Il1b | Alliance of Genome Resources | ||||
| cyclic hematopoiesis | ELANE* | Elane | Alliance of Genome Resources | ||||
| hypereosinophilic syndrome | PDGFRA* | Pdgfra | Alliance of Genome Resources | ||||
| hypereosinophilic syndrome | F5* | F5 | Alliance of Genome Resources | ||||
| leukocyte adhesion deficiency | ITGB2* | Itgb2, Itgb2l | Alliance of Genome Resources | ||||
| leukocyte adhesion deficiency 1 | FERMT3* | Fermt3 | Alliance of Genome Resources | ||||
| leukopenia | GSTM1*, GSTM5 | Gstm1, Gstm2, Gstm3, Gstm6 | Alliance of Genome Resources | ||||
| leukopenia | CXCR4* | Cxcr4 | Alliance of Genome Resources | ||||
| leukopenia | TPMT* | Tpmt | Alliance of Genome Resources | ||||
| leukopenia | GSTT1* | Gstt1 | Alliance of Genome Resources | ||||
| leukostasis | SERPINF1* | Serpinf1 | Alliance of Genome Resources | ||||
| lymphopenia | FCGR2A*, FCGR2B, FCGR2C | Fcgr2b, Fcgr3 | Alliance of Genome Resources | ||||
| lymphopenia | IL2RA* | Il2ra | Alliance of Genome Resources | ||||
| lymphopenia | FCGR3A*, FCGR3B | Fcgr4 | Alliance of Genome Resources | ||||
| mastocytosis | IL13* | Il13 | Alliance of Genome Resources | ||||
| multiple myeloma | TYMS* | Tyms | Alliance of Genome Resources | ||||
| multiple myeloma | PF4*, PF4V1 | Pf4 | Alliance of Genome Resources | ||||
| multiple myeloma | POLR1G* | Polr1g | Alliance of Genome Resources | ||||
| multiple myeloma | PON1* | Pon1 | Alliance of Genome Resources | ||||
| multiple myeloma | RBP1* | Rbp1 | Alliance of Genome Resources | ||||
| multiple myeloma | ROBO1* | Robo1 | Alliance of Genome Resources | ||||
| multiple myeloma | SOD2* | Sod2 | Alliance of Genome Resources | ||||
| multiple myeloma | SPARC* | Sparc | Alliance of Genome Resources | ||||
| multiple myeloma | SPP1* | Spp1 | Alliance of Genome Resources | ||||
| multiple myeloma | TFRC* | Tfrc | Alliance of Genome Resources | ||||
| multiple myeloma | TGFB1* | Tgfb1 | Alliance of Genome Resources | ||||
| multiple myeloma | TNF* | Tnf | Alliance of Genome Resources | ||||
| multiple myeloma | TNFRSF10A*, TNFRSF10B, TNFRSF10C, TNFRSF10D | Tnfrsf10b | Alliance of Genome Resources | ||||
| multiple myeloma | TNFRSF17* | Tnfrsf17 | Alliance of Genome Resources | ||||
| multiple myeloma | TP53* | Trp53 | Alliance of Genome Resources | ||||
| multiple myeloma | VEGFA* | Vegfa | Alliance of Genome Resources | ||||
| multiple myeloma | XPO5* | Xpo5 | Alliance of Genome Resources | ||||
| multiple myeloma | XRCC3* | Xrcc3 | Alliance of Genome Resources | ||||
| multiple myeloma | XRCC4* | Xrcc4 | Alliance of Genome Resources | ||||
| multiple myeloma | XRCC5* | Xrcc5 | Alliance of Genome Resources | ||||
| multiple myeloma | ABCG2* | Abcg2, Abcg3 | Alliance of Genome Resources | ||||
| multiple myeloma | ACE* | Ace | Alliance of Genome Resources | ||||
| multiple myeloma | APOE* | Apoe | Alliance of Genome Resources | ||||
| multiple myeloma | BCL2L10* | Bcl2l10 | Alliance of Genome Resources | ||||
| multiple myeloma | CBX7* | Cbx7 | Alliance of Genome Resources | ||||
| multiple myeloma | CCND1* | Ccnd1 | Alliance of Genome Resources | ||||
| multiple myeloma | CD40* | Cd40 | Alliance of Genome Resources | ||||
| multiple myeloma | CD40LG* | Cd40lg | Alliance of Genome Resources | ||||
| multiple myeloma | CDKN2A* | Cdkn2a | Alliance of Genome Resources | ||||
| multiple myeloma | CFHR1*, CFHR2 | Cfhr1 | Alliance of Genome Resources | ||||
| multiple myeloma | CTLA4* | Ctla4 | Alliance of Genome Resources | ||||
| multiple myeloma | CYP1A1* | Cyp1a1 | Alliance of Genome Resources | ||||
| multiple myeloma | CYP2C19*, CYP2C8, CYP2C9, CYP2C18 | Cyp2c29, Cyp2c37, Cyp2c38, Cyp2c39, Cyp2c50, Cyp2c55, Cyp2c65, Cyp2c66 | Alliance of Genome Resources | ||||
| multiple myeloma | EPHX1* | Ephx1 | Alliance of Genome Resources | ||||
| multiple myeloma | ERCC1* | Ercc1 | Alliance of Genome Resources | ||||
| multiple myeloma | ERCC2* | Ercc2 | Alliance of Genome Resources | ||||
| multiple myeloma | FCGR2A*, FCGR2B, FCGR2C | Fcgr2b, Fcgr3 | Alliance of Genome Resources | ||||
| multiple myeloma | FGG* | Fgg | Alliance of Genome Resources | ||||
| multiple myeloma | GPX1* | Gpx1 | Alliance of Genome Resources | ||||
| multiple myeloma | GPX3* | Gpx3 | Alliance of Genome Resources | ||||
| multiple myeloma | GSTM1*, GSTM5 | Gstm1, Gstm2, Gstm3, Gstm6 | Alliance of Genome Resources | ||||
| multiple myeloma | GSTP1* | Gstp1, Gstp2, Gstp3, Gstp-ps | Alliance of Genome Resources | ||||
| multiple myeloma | GSTT1* | Gstt1 | Alliance of Genome Resources | ||||
| multiple myeloma | HFE* | Hfe | Alliance of Genome Resources | ||||
| multiple myeloma | HK1* | Hk1 | Alliance of Genome Resources | ||||
| multiple myeloma | ICAM1* | Icam1 | Alliance of Genome Resources | ||||
| multiple myeloma | IL1A* | Il1a | Alliance of Genome Resources | ||||
| multiple myeloma | IL1B* | Il1b | Alliance of Genome Resources | ||||
| multiple myeloma | IL1RN* | Il1rn | Alliance of Genome Resources | ||||
| multiple myeloma | IL4R* | Il4ra | Alliance of Genome Resources | ||||
| multiple myeloma | IL10* | Il10 | Alliance of Genome Resources | ||||
| multiple myeloma | IRF4* | Irf4 | Alliance of Genome Resources | ||||
| multiple myeloma | IRF8* | Irf8 | Alliance of Genome Resources | ||||
| multiple myeloma | KRAS* | Kras | Alliance of Genome Resources | ||||
| multiple myeloma | LIG4* | Lig4 | Alliance of Genome Resources | ||||
| multiple myeloma | MEFV* | Mefv | Alliance of Genome Resources | ||||
| multiple myeloma | MET* | Met | Alliance of Genome Resources | ||||
| multiple myeloma | MIR320A* | Mir320 | Alliance of Genome Resources | ||||
| multiple myeloma | MTHFR* | Mthfr | Alliance of Genome Resources | ||||
| multiple myeloma | MTR* | Mtr | Alliance of Genome Resources | ||||
| multiple myeloma | MTRR* | Mtrr | Alliance of Genome Resources | ||||
| multiple myeloma | NFKBIA* | Nfkbia | Alliance of Genome Resources | ||||
| multiple myeloma | NQO1* | Nqo1 | Alliance of Genome Resources | ||||
| multiple myeloma | NRAS* | Nras | Alliance of Genome Resources | ||||
| neutropenia | FCGR2A*, FCGR2B, FCGR2C | Fcgr2b, Fcgr3 | Alliance of Genome Resources | ||||
| neutropenia | CSF3* | Csf3 | Alliance of Genome Resources | ||||
| neutropenia | CSF2* | Csf2 | Alliance of Genome Resources | ||||
| neutropenia | GSTT1* | Gstt1 | Alliance of Genome Resources | ||||
| neutropenia | TNF* | Tnf | Alliance of Genome Resources | ||||
| neutropenia | AP3B1* | Ap3b1 | Alliance of Genome Resources | ||||
| neutropenia | STAT2* | Stat2 | Alliance of Genome Resources | ||||
| neutropenia | C5* | Hc | Alliance of Genome Resources | ||||
| severe congenital neutropenia | SRP68* | Srp68 | Alliance of Genome Resources | ||||
| severe congenital neutropenia | ELANE* | Elane | Alliance of Genome Resources | ||||
| severe congenital neutropenia | CSF3R* | Csf3r | Alliance of Genome Resources | ||||
| severe congenital neutropenia | CLPB* | Clpb | Alliance of Genome Resources | ||||
| severe congenital neutropenia | SEC61A1* | Sec61a1 | Alliance of Genome Resources | ||||
| severe congenital neutropenia 1 | ELANE* | Elane | Alliance of Genome Resources | ||||
| severe congenital neutropenia 2 | GFI1* | Gfi1 | Alliance of Genome Resources | ||||
| severe congenital neutropenia 3 | HAX1* | Hax1 | Alliance of Genome Resources | ||||
| severe congenital neutropenia 4 | G6PC3* | G6pc3 | Alliance of Genome Resources | ||||
| severe congenital neutropenia 5 | VPS45* | Vps45 | Alliance of Genome Resources | ||||
| severe congenital neutropenia 6 | JAGN1* | Jagn1 | Alliance of Genome Resources | ||||
| severe congenital neutropenia 7 | CSF3R* | Csf3r | Alliance of Genome Resources | ||||
| severe congenital neutropenia 8 | SRP54* | Srp54a, Srp54b, Srp54c | Alliance of Genome Resources | ||||
| SM-AHNMD | ASXL1* | Asxl1 | Alliance of Genome Resources | ||||
| X-linked severe congenital neutropenia | WAS* | Was | Alliance of Genome Resources | ||||
Excel File
|
Transgenes and other genome features developed in mice to model this disease.
|
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| Disease Term | Transgenes and Other Genome Features | Mouse Models | |
| mastocytosis | Tg(Kit*D814V)1Roer | 2 models | |
| mastocytosis | Tg(Kit*D814V)2Roer | 1 model | |
| mastocytosis | Tg(Kit*D814V)3Roer | 2 models | |
| multiple myeloma | Tg(Cd4-NPM/ALK)N1Ingh | 1 model | |
| multiple myeloma | Tg(Igh-Maf)68Staka | 1 model | |
| multiple myeloma | Tg(Igh-Maf)524Staka | 1 model | |
| multiple myeloma | Tg(Igkv3-5*-MYC)24Plbe | 1 model | |