 Excel File
Text File
All mouse models of Charcot-Marie-Tooth disease type 2 with phenotypic similarity to the human disease
|
||||||||
| Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
  | Charcot-Marie-Tooth disease axonal type 2K | Gdap1tm1.2Geno/Gdap1tm1.2Geno | involves: 129 * C57BL/6 | J:224701 | View | |||
| Charcot-Marie-Tooth disease axonal type 2O | Dync1h1tm1.1Sjki/Dync1h1+ | involves: 129 * 129S1/SvImJ * C57BL/6 * C57BL/6J | J:264493 | View | ||||
| Charcot-Marie-Tooth disease axonal type 2P | Lrsam1Gt(RRK461)Byg/Lrsam1Gt(RRK461)Byg | involves: 129P2/OlaHsd | J:196447 | View | ||||
| Charcot-Marie-Tooth disease axonal type 2Q | Dhtkd1tm1Mmgu/Dhtkd1tm1Mmgu | involves: 129S6/SvEvTac * C57BL/6J | J:288186 | View | ||||
| Charcot-Marie-Tooth disease axonal type 2Q | Dhtkd1tm1Zgwg/Dhtkd1tm1Zgwg | involves: C57BL/6 | J:267178 | View | ||||
| Charcot-Marie-Tooth disease axonal type 2S | Ighmbp2em1Cx/Ighmbp2em1Cx | C57BL/6J-Ighmbp2em1Cx/Cx | J:337488 | View | ||||
| Charcot-Marie-Tooth disease axonal type 2S | Ighmbp2em5Cx/Ighmbp2em5Cx | C57BL/6J-Ighmbp2em5Cx/Cx | J:337488 | View | ||||
| Charcot-Marie-Tooth disease axonal type 2Z | Morc2aem1Snupy/Morc2a+ | involves: C57BL/6 | J:341847 | View | ||||
| Charcot-Marie-Tooth disease type 2A1 | Kif1btm1Noh/Kif1b+ | involves: 129S4/SvJae * C57BL/6J | J:69772 | View | ||||
| Charcot-Marie-Tooth disease type 2A2A | Tg(Mnx1-Mfn2*T105M,-EGFP)1Dcc/Tg(Mnx1-Mfn2*T105M,-EGFP)1Dcc | Not Specified | J:132035 | View | ||||
| Charcot-Marie-Tooth disease type 2B | Rab7em2Rwb/Rab7+ | C57BL/6J-Rab7em2Rwb/RwbJ | J:346904 | View | ||||
| Charcot-Marie-Tooth disease type 2B1 | Lmnatm1Stw/Lmnatm1Stw | involves: 129S1/Sv | J:75378 | View | ||||
| Charcot-Marie-Tooth disease type 2D | Gars1C201R/Gars1+ | involves: BALB/cAnN * C3H/HeH * C57BL/6J | J:149830, J:179811 | View | ||||
| Charcot-Marie-Tooth disease type 2D | Gars1em1Rwb/Gars1em2Rwb | involves: C57BL/6NJ * FVB/NJ | J:284948 | View | ||||
| Charcot-Marie-Tooth disease type 2D | Gars1Nmf249/Gars1+ | C57BL/6J-Gars1Nmf249/J | J:112221 | View | ||||
| Charcot-Marie-Tooth disease type 2D | Gars1Nmf249/Gars1+ | involves: C57BL/6J * CAST/Ei | J:179811 | View | ||||
| Charcot-Marie-Tooth disease type 2E | Nefltm2.1Liem/Nefl+ | B6.Cg-Nefltm2.1Liem | J:220605 | View | ||||
| Transgenes and Other Mutations | Charcot-Marie-Tooth disease axonal type 2F | Tg(Thy1-HSPB1*S135F)#Lvdb/0 | involves: FVB/N | J:174508 | View | |||
| Charcot-Marie-Tooth disease type 2A2A | Tg(Eno2-MFN2*R94Q)L51Ugfm/0 | involves: C57BL/6 * C57BL/6J * DBA/2 | J:158936 | View | ||||
| Charcot-Marie-Tooth disease type 2A2A | Tg(Eno2-MFN2*R94Q)L51Ugfm/0 | involves: C57BL/6 * DBA/2 | J:173431 | View | ||||
| Charcot-Marie-Tooth disease type 2A2A | Tg(Eno2-MFN2*R94Q)L87Ugfm/Tg(Eno2-MFN2*R94Q)L87Ugfm | involves: C57BL/6 * DBA/2 | J:173431 | View | ||||
| Charcot-Marie-Tooth disease type 2E | Tg(NEFL*E397K)#Milg/0 | Not Specified | J:173771 | View | ||||
| Charcot-Marie-Tooth disease type 2E |
Tg(tetO-NEFL)173.2Jpj/0 Tg(THY1-tTA)177Jpj/0 |
involves: C3H * C57BL/6 | J:160704 | View | ||||
| Additional Complex Models | Charcot-Marie-Tooth disease type 2A2A |
Gt(ROSA)26Sortm1(CAG-MFN2*T105M)Dple/Gt(ROSA)26Sor+ Tg(Nes-cre)1Kln/0 |
involves: C57BL/6 * SJL | J:251584 | View | |||
|
No similarity to the expected human disease phenotype was found.
|
||||||||
| Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
| NOT Models | Charcot-Marie-Tooth disease type 2B1 | Lmnatm1.1Vde/Lmnatm1.1Vde | B6.129(Cg)-Lmnatm1.1Vde | J:322912 | View | |||