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All mouse models of inflammatory bowel disease with phenotypic similarity to the human disease
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| Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
  | inflammatory bowel disease | Il10tm1Cgn/Il10tm1Cgn | B6.129P2-Il10tm1Cgn/J | J:124308, J:149347 | View | |||
| inflammatory bowel disease | Il10tm1Cgn/Il10tm1Cgn | involves: 129P2/OlaHsd * C57BL/6 | J:15222, J:35020 | View | ||||
| inflammatory bowel disease |
Il10tm1Cgn/Il10tm1Cgn Tg(MUC1)79.24Gend/0 |
B6.Cg-Il10tm1Cgn Tg(MUC1)79.24Gend | J:149347 | View | ||||
| inflammatory bowel disease 10 | Atg16l1Gt(BC0122)Wtsi/Atg16l1Gt(BC0122)Wtsi | involves: 129P2/OlaHsd * C57BL/6 | J:141419 | View | ||||
| inflammatory bowel disease 10 | Atg16l1Gt(XR0164)Wtsi/Atg16l1Gt(XR0164)Wtsi | involves: 129P2/OlaHsd * C57BL/6 | J:141419 | View | ||||
| inflammatory bowel disease 13 | Abcb1atm1Bor/Abcb1atm1Bor | FVB.129P2-Abcb1atm1Bor/TacImx | J:51190 | View | ||||
| | Crohn's disease | Efstm1Kale/Efstm1Kale | either: (involves: 129X1/SvJ) or (involves: 129X1/SvJ * C57BL/6J) | J:103757 | View | |||
| Crohn's disease |
Pikfyvetm2.1Tssk/Pikfyvetm2.1Tssk Tg(Vil1-cre)20Syr/0 |
involves: 129P2/OlaHsd * C57BL/6 * DBA/2 | J:193689 | View | ||||
| inflammatory bowel disease |
B2mtm1Unc/B2mtm1Unc Il2tm1Hor/Il2tm1Hor |
involves: 129 * C57BL/6 | J:51450 | View | ||||
| inflammatory bowel disease | Il2tm1Hor/Il2tm1Hor | involves: 129P2/OlaHsd * C57BL/6 | J:15223 | View | ||||
| inflammatory bowel disease | Il2ratm1Dw/Il2ratm1Dw | involves: 129S4/SvJae * C57BL/6 | J:64279 | View | ||||
| inflammatory bowel disease | Muc2eey/Muc2eey | C57BL/6-Muc2eey | J:194148 | View | ||||
| inflammatory bowel disease | Muc2tm1Avel/Muc2tm1Avel | involves: 129P2/OlaHsd * C57BL/6 | J:216831 | View | ||||
| inflammatory bowel disease | Muc2wnn/Muc2wnn | C57BL/6-Muc2wnn | J:194148 | View | ||||
| inflammatory bowel disease | Nfil3tm1Pbro/Nfil3tm1Pbro | B6.129S6-Nfil3tm1Pbro | J:209365 | View | ||||
| inflammatory bowel disease | Runx3tm1Yg/Runx3tm1Yg | either: (involves: 129S1/Sv * 129X1/SvJ * ICR) or (involves: 129S1/Sv * 129X1/SvJ * MF1) | J:93240 | View | ||||
| inflammatory bowel disease | St6galnac1em1Len/St6galnac1em1Len | Not Specified | J:324883 | View | ||||
| inflammatory bowel disease |
Stat3tm1Dlv/Stat3tm1Dlv Tg(Csf1r-icre)1Jwp/0 |
involves: 129P2/OlaHsd * C57BL/6 * FVB | J:156593 | View | ||||
| inflammatory bowel disease |
Stat3tm1Flv/Stat3tm1Flv Tg(Tek-cre)1Xyfu/0 |
involves: C57BL/6 | J:86655 | View | ||||
| inflammatory bowel disease |
Stat3tm1Flv/Stat3tm1Flv Tg(Tek-cre)12Flv/0 |
involves: 129 * C3H * C57BL/6 | J:81973 | View | ||||
| inflammatory bowel disease | Tg(Igh-V-CD40lg)#Tsub/0 | involves: C57BL/6 | J:89855 | View | ||||
| inflammatory bowel disease | Tnftm1Gkl/Tnftm2Gkl | involves: 129S/SvEv * C57BL/6 | J:54056 | View | ||||
| inflammatory bowel disease |
Tnftm2.1Gkl/Tnftm2.1Gkl Tg(Fabp1-cre)1Jig/0 |
involves: 129S/SvEv * FVB/N | J:204557 | View | ||||
| inflammatory bowel disease | Tnftm2Gkl/Tnf+ | involves: 129S/SvEv * C57BL/6 | J:54056, J:136667, J:204922 | View | ||||
| inflammatory bowel disease | Tnftm2Gkl/Tnftm2Gkl | involves: 129S/SvEv * C57BL/6 | J:54056 | View | ||||
| inflammatory bowel disease |
Xbp1tm2Glm/Xbp1tm2Glm Tg(Vil1-cre)997Gum/0 |
involves: 129S6/SvEvTac * C57BL/6J * FVB/N * SJL | J:188627 | View | ||||
| inflammatory bowel disease 1 | Nod2tm1Mka/Nod2tm1Mka | involves: C57BL/6 | J:96128 | View | ||||
| inflammatory bowel disease 12 | Gnai2tm1Lbi/Gnai2tm1Lbi | involves: 129S7/SvEvBrd | J:24434, J:30507 | View | ||||
| inflammatory bowel disease 12 | Gnai2tm1Lbi/Gnai2tm1Lbi | involves: 129S7/SvEvBrd * C57BL/6 | J:91100 | View | ||||
| inflammatory bowel disease 12 | Gnai2tm1Lbi/Gnai2tm1Lbi | involves: 129S7/SvEvBrd * C57BL/6J | J:24434 | View | ||||
| inflammatory bowel disease 16 | Tg(Csf1r-Tnfsf15,-EGFP)#Targ/0 | involves: C57BL/6 | J:169462 | View | ||||
| inflammatory bowel disease 16 | Tg(Lck-Tnfsf15,-EGFP)#Targ/0 | involves: C57BL/6 | J:169462 | View | ||||
| Transgenes and Other Mutations | inflammatory bowel disease | Tcratm1Mom/Tcratm1Mom | B6.129S2-Tcratm1Mom | J:135597 | View | |||
| inflammatory bowel disease | Tcratm1Mom/Tcratm1Mom | involves: 129S2/SvPas * C57BL/6 | J:15221 | View | ||||
| Additional Complex Models | inflammatory bowel disease |
Gpx1tm1Ysh/Gpx1+ Gpx2tm2Coh/Gpx2tm2Coh |
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J | J:71506 | View | |||
| inflammatory bowel disease |
Gpx1tm1Ysh/Gpx1tm1Ysh Gpx2tm2Coh/Gpx2tm2Coh |
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J | J:71506 | View | ||||
| inflammatory bowel disease |
Il10rbtm1Agt/Il10rbtm1Agt Tg(Cd4-TGFBR2)16Flv/? |
involves: 129S2/SvPas * C3H * C57BL/6 | J:134156 | View | ||||
| ulcerative colitis |
Rag2tm1Fwa/Rag2tm1Fwa Tbx21tm1Glm/Tbx21tm1Glm |
involves: 129S/SvEv * 129S6/SvEvTac | J:141481 | View | ||||
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No similarity to the expected human disease phenotype was found.
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| Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
| NOT Models | inflammatory bowel disease 12 | Gnai2tm1Lbi/Gnai2tm1Lbi | 129-Gnai2tm1Lbi | J:91100 | View | |||