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All mouse models of respiratory system cancer with phenotypic similarity to the human disease
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| Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
  | lung cancer |
Cdk6tm1Bbd/Cdk6tm1Bbd Krastm1Bbd/Kras+ Polr2atm1(cre/ERT2)Bbd/Polr2atm1(cre/ERT2)Bbd |
involves: 129S1/Sv * 129X1/SvJ | J:161780 | View | |||
| lung cancer |
Cdkn2atm4Rdp/Cdkn2atm4Rdp Krastm4Tyj/Kras+ |
involves: 129S4/SvJae | J:195492 | View | ||||
| lung cancer | Krastm1Bbd/Kras+ | involves: 129S1/Sv * 129X1/SvJ | J:172200 | View | ||||
| lung cancer |
Krastm1Bbd/Kras+ Polr2atm1(cre/ERT2)Bbd/Polr2atm1(cre/ERT2)Bbd |
involves: 129S1/Sv * 129X1/SvJ | J:161780 | View | ||||
| lung cancer |
Krastm1Bbd/Krastm2Bbd Polr2atm1(cre/ERT2)Bbd/Polr2atm1(cre/ERT2)Bbd |
involves: 129S1/Sv * 129X1/SvJ | J:161780 | View | ||||
| lung cancer | Krastm2Tyj/Kras+ | involves: 129S2/SvPas | J:68981, J:136369 | View | ||||
| lung cancer | Krastm2Tyj/Kras+ | involves: 129S2/SvPas * C57BL/6 | J:68981 | View | ||||
| lung cancer |
Krastm2Tyj/Kras+ Trp53tm1Glo/Trp53+ |
involves: 129S2/SvPas * 129S7/SvEvBrd | J:129627 | View | ||||
| lung cancer | Krastm3Tyj/Kras+ | involves: 129S4/SvJae | J:68981 | View | ||||
| lung cancer | Krastm3Tyj/Kras+ | involves: 129S4/SvJae * C57BL/6 | J:68981 | View | ||||
| lung cancer | Krastm4Tyj/Kras+ | involves: 129S4/SvJae | J:207982 | View | ||||
| lung cancer | Krastm4Tyj/Kras+ | involves: 129S4/SvJae * C57BL/6 | J:203686 | View | ||||
| lung cancer |
Krastm4Tyj/Kras+ Scribtm1.1Phum/Scrib+ |
involves: 129S4/SvJae | J:216266 | View | ||||
| lung cancer |
Krastm4Tyj/Kras+ Scribtm1.1Phum/Scribtm1.1Phum |
involves: 129S4/SvJae | J:216266 | View | ||||
| lung cancer |
Krastm4Tyj/Kras+ Tgfbr2tm1.2Hlm/Tgfbr2tm1.2Hlm |
B6.129-Krastm4Tyj Tgfbr2tm1.2Hlm | J:177379 | View | ||||
| lung cancer |
Krastm4Tyj/Kras+ Trp53tm1Brn/Trp53tm1Brn |
involves: 129P2/OlaHsd * 129S4/SvJae | J:103407, J:154041, J:195492, J:203686 | View | ||||
| lung cancer |
Krastm4Tyj/Kras+ Trp53tm1Lejo/Trp53tm1Lejo |
involves: 129S4/SvJae | J:187012 | View | ||||
| lung cancer |
Krastm4Tyj/Kras+ Trp53tm2Tyj/Trp53+ |
involves: 129S4/SvJae | J:191425 | View | ||||
| lung cancer | Krastm5Tyj/Kras+ | involves: 129S4/SvJae * C57BL/6 | J:172206 | View | ||||
| | lung cancer |
Foxm1tm1Rhc/Foxm1tm1Rhc Tg(Tek-cre)1Ywa/0 |
involves: 129X1/SvJ * C57BL/6 * SJL | J:167773 | View | |||
| lung cancer |
Gadd45atm1Ajf/Gadd45atm1Ajf Xpctm1Ecf/Xpctm1Ecf |
either: (involves: 129/Sv * 129P2/OlaHsd * C57BL/6) or (involves: 129/Sv * 129X1/SvJ * C57BL/6) | J:101421 | View | ||||
| lung cancer | Robo1tm1Phr/Robo1+ | involves: 129P2/OlaHsd * C57BL/6 | J:93666 | View | ||||
| lung cancer |
Tg(SFTPC-rtTA)5Jaw/0 Tg(tetO-Fgf9,-EGFP)#Dor/0 |
involves: FVB | J:204282 | View | ||||
| lung cancer | Xpctm1Ecf/Xpctm1Ecf | involves: 129 * C57BL/6 | J:101421 | View | ||||
| pleuropulmonary blastoma |
Tg(SFTPC-rtTA)5Jaw/0 Tg(tetO-Fgf9,-EGFP)#Dor/0 |
involves: FVB | J:224791 | View | ||||
| pleuropulmonary blastoma |
Yy1tm2.1Yshi/Yy1tm2.1Yshi Tg(Nkx2-1-cre)2Sand/0 |
involves: 129S4/SvJae * C57BL/6J | J:239777 | View | ||||
| Transgenes and Other Mutations | adenosquamous lung carcinoma |
Tg(Scgb1a1-rtTA)1Jaw/0 Tg(tetO-ERBB2*)5BKkw/0 |
involves: FVB/N | J:143874 | View | |||
| adenosquamous lung carcinoma |
Tg(Scgb1a1-rtTA)1Jaw/0 Tg(tetO-ERBB2*)26Kkw/0 |
involves: FVB/N | J:143874 | View | ||||
| lung adenocarcinoma |
Tg(Scgb1a1-rtTA)1Jaw/0 Tg(tetO-Kras2)12Hev/0 |
involves: 129 * C57BL/6 * FVB/N | J:73468 | View | ||||
| lung adenocarcinoma | Tg(SFTPC-env)1Yhch/0 | FVB/N-Tg(SFTPC-env)1Yhch | J:247986 | View | ||||
| lung cancer | Tg(ACTB-KRAS*G12V,-luc)#Lche/0 | involves: C57BL/6 * FVB/N | J:199528 | View | ||||
| lung cancer |
Tg(Scgb1a1-rtTA)1Jaw/0 Tg(tetO-EGFR*)#Kkw/0 |
involves: 129 * C57BL/6 * FVB/N | J:156440, J:235747 | View | ||||
| lung cancer |
Tg(Scgb1a1-rtTA)1Jaw/0 Tg(tetO-EGFR*delta19)11Hev/0 |
involves: C57BL/6 * CBA | J:109092 | View | ||||
| lung cancer |
Tg(Scgb1a1-rtTA)1Jaw/0 Tg(tetO-EGFR*L858R)56Hev/0 |
involves: C57BL/6 * CBA | J:109092 | View | ||||
| lung cancer |
Tg(Scgb1a1-rtTA)1Jaw/0 Tg(tetO-EGFR*L858R)57Hev/0 |
involves: C57BL/6 * CBA | J:109092 | View | ||||
| lung cancer |
Tg(Scgb1a1-rtTA)1Jaw/0 Tg(tetO-EGFR*L858R)#Hev/0 |
involves: 129 * C57BL/6 * CBA | J:128700, J:213447 | View | ||||
| lung cancer |
Tg(Scgb1a1-rtTA)1Jaw/0 Tg(tetO-EGFR*T790M)8Paow/0 |
involves: 129 * C57BL/6 * FVB/N | J:128700 | View | ||||
| lung cancer |
Tg(Scgb1a1-rtTA)1Jaw/0 Tg(tetO-EGFR*T790M*L858R)19Kkw/0 |
involves: 129 * C57BL/6 * FVB/N | J:122849, J:156440, J:235747 | View | ||||
| lung cancer |
Tg(Scgb1a1-rtTA)1Jaw/0 Tg(tetO-EGFR*T790M*L858R)51Paow/0 |
involves: 129 * C57BL/6 * FVB/N | J:128700 | View | ||||
| lung cancer |
Tg(Scgb1a1-rtTA)1Jaw/0 Tg(tetO-IGF1R)1Ramo/0 |
involves: 129 * C57BL/6 * FVB | J:271820 | View | ||||
| lung cancer |
Tg(Scgb1a1-rtTA)1Jaw/0 Tg(tetO-PIK3CA*H1047R)13Lca/0 |
involves: 129 * C57BL/6 * FVB/N | J:142254 | View | ||||
| lung cancer |
Tg(Scgb1a1-rtTA)1Jaw/0 Tg(tetO-PTPN11*E76K)#Jiwu/0 |
involves: 129 * C57BL/6 * FVB/N | J:212505 | View | ||||
| lung cancer | Tg(SFTPC-CD74/ROS1)125Tno/0 | C57BL/6J-Tg(SFTPC-CD74/ROS1)125Tno | J:231770 | View | ||||
| lung cancer | Tg(SFTPC-EGFR*L858R)4-3Kkiu/0 | involves: C57BL/6Cr | J:152157 | View | ||||
| lung cancer | Tg(SFTPC-EML4/ALK)502-4Hima/0 | involves: C57BL/6J | J:142679 | View | ||||
| lung cancer | Tg(SFTPC-env)1Yhch/0 | FVB/N-Tg(SFTPC-env)1Yhch | J:153538 | View | ||||
| lung cancer | Tg(SFTPC-EZR/ROS1)AShiba/0 | C57BL/6-Tg(SFTPC-EZR/ROS1)AShiba | J:199415 | View | ||||
| lung cancer | Tg(SFTPC-KIF5B/RET)1Tkoh/0 | involves: C57BL/6J | J:215989 | View | ||||
| lung cancer |
Tg(SFTPC-rtTA)5Jaw/0 Tg(tetO-IGF1R)1Ramo/0 |
involves: FVB | J:271820 | View | ||||
| lung cancer | Tg(SFTPC-SDC4/ROS1)141Tno/0 | C57BL/6J-Tg(SFTPC-SDC4/ROS1)141Tno | J:231770 | View | ||||
| lung cancer | Tg(Utg-TAg)7593Fjd/? | involves: FVB | J:70785 | View | ||||
| lung cancer | Tg(Utg-TAg)7736Fjd/? | involves: FVB | J:70785 | View | ||||
| lung cancer | Tg(Utg-TAg)#Fjd/? | involves: FVB | J:70785 | View | ||||
| Additional Complex Models | lung cancer | Col1a1tm1(CAG-EGFR*T790M*C797S*L858R)Mje/Col1a1+ | involves: 129S4/SvJae * BALB/c * C57BL/6 | J:235747 | View | |||
| lung cancer |
Col1a1tm1(tetO-EML4/ALK)Kkw/Col1a1+ Tg(Scgb1a1-rtTA)1Jaw/0 |
involves: 129 * C57BL/6 | J:166724 | View | ||||
| lung cancer | Col1a1tm4(CAG-FGFR2_iIIIb*K660N)Kkw/Col1a1+ | involves: 129S4/SvJae * BALB/c * C57BL/6 | J:214230 | View | ||||
| lung cancer |
Col1a1tm4(CAG-FGFR2_iIIIb*K660N)Kkw/Col1a1+ Trp53tm1Brn/Trp53tm1Brn |
involves: 129P2/OlaHsd * 129S4/SvJae * BALB/c * C57BL/6 | J:214230 | View | ||||
| lung cancer |
Col1a1tm5(CAG-FGFR2_iIIIb*W290C)Kkw/Col1a1+ Trp53tm1Brn/Trp53tm1Brn |
involves: 129P2/OlaHsd * 129S4/SvJae * BALB/c * C57BL/6 | J:214230 | View | ||||
| lung cancer |
Ctnnb1tm1Mmt/Ctnnb1+ Fgfr3tm4Cxd/Fgfr3+ Tg(Upk2-cre)6Xrw/0 |
involves: 129S6/SvEvTac * 129X1/SvJ * FVB/N | J:174242 | View | ||||
| lung non-small cell carcinoma |
Col1a1tm1(tetO-EML4/ALK)Kkw/Col1a1+ Tg(Scgb1a1-rtTA)1Jaw/0 |
involves: 129 * C57BL/6 | J:166724 | View | ||||
| lung non-small cell carcinoma |
Krastm4Tyj/Kras+ Stk11tm1.1Rdp/Stk11tm1.1Rdp |
involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6 * FVB/N | J:124682 | View | ||||
| lung non-small cell carcinoma |
Krastm4Tyj/Kras+ Stk11tm1.1Rdp/Stk11tm1.2Rdp |
involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6 * FVB/N | J:124682 | View | ||||
| lung small cell carcinoma |
Rb1tm2Brn/Rb1tm2Brn Trp53tm1Brn/Trp53tm1Brn |
involves: 129P2/OlaHsd | J:86077, J:157319 | View | ||||
| lung small cell carcinoma |
Rb1tm2Brn/Rb1tm2Brn Trp53tm1Lejo/Trp53tm1Lejo |
involves: 129 | J:187012 | View | ||||
| lung small cell carcinoma |
Rb1tm3Tyj/Rb1tm3Tyj Rbl2tm2Tyj/Rbl2tm2Tyj Trp53tm1Brn/Trp53tm1Brn |
involves: 129P2/OlaHsd * 129S4/SvJae | J:160148 | View | ||||
| lung small cell carcinoma |
Rb1tm3Tyj/Rb1tm3Tyj Trp53tm1Brn/Trp53tm1Brn |
involves: 129P2/OlaHsd * 129S4/SvJae | J:160148 | View | ||||
| lung squamous cell carcinoma |
Nr1h2tm1.1Gstr/Nr1h2tm1.1Gstr Nr1h3tm1.1Gstr/Nr1h3tm1.1Gstr |
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 | J:234268 | View | ||||