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All mouse models of artery disease with phenotypic similarity to the human disease
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| Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
  | aortic aneurysm |
Agtr2tm1Tin/Y Efemp2tm1.1Hiya/Efemp2tm1.2Hiya Tg(Tagln-cre)1Her/0 |
involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6 * SJL | J:213282 | View | |||
| aortic aneurysm |
Efemp2tm1.1Hiya/Efemp2tm1.2Hiya Tg(Tagln-cre)1Her/0 |
involves: 129S6/SvEvTac * C57BL/6 * SJL | J:213282 | View | ||||
| arterial calcification of infancy | Enpp1asj-2J/Enpp1asj-2J | BALB/cJ-Enpp1asj-2J/GrsrJ | J:215824 | View | ||||
| arterial calcification of infancy | Enpp1asj/Enpp1asj | C57BL/6J-Enpp1asj/GrsrJ | J:201689 | View | ||||
| essential hypertension | Nos3tm1Gdk/Nos3tm1Gdk | involves: 129P2/OlaHsd * C57BL/6 | J:46061 | View | ||||
| essential hypertension | Nos3tm1Plh/Nos3tm1Plh | involves: 129S4/SvJae | J:28778 | View | ||||
| essential hypertension | Nos3tm1Unc/Nos3tm1Unc | involves: 129P2/OlaHsd | J:103153 | View | ||||
| Marfan syndrome | Fbn1tm1Hcd/Fbn1+ | involves: 129S1/Sv * 129X1/SvJ * C57BL/6J | J:91349, J:94428 | View | ||||
| Marfan syndrome | Fbn1tm1Lper/Fbn1+ | involves: 129/Sv * C57BL/6 * CD-1 | J:167276 | View | ||||
| Marfan syndrome | Fbn1tm1Lper/Fbn1+ | involves: 129/Sv * CD-1 | J:167276 | View | ||||
| Marfan syndrome | Fbn1tm1Rmz/Fbn1tm1Rmz | involves: 129S4/SvJae * C57BL/6J | J:43199 | View | ||||
| Marfan syndrome | Fbn1tm2Rmz/Fbn1tm2Rmz | involves: 129S1/Sv * 129X1/SvJ | J:54081 | View | ||||
| Marfan syndrome | Fbn1tm3Rmz/Fbn1tm3Rmz | Not Specified | J:110586 | View | ||||
| Marfan syndrome | Fbn1Tsk/Fbn1+ | B6.Cg-Fbn1Tsk | J:30961 | View | ||||
| Marfan syndrome | Fbn1Tsk/Fbn1+ | B10.D2/(58N)Sn | J:21512 | View | ||||
| persistent fetal circulation syndrome | Foxf1em1Vvk/Foxf1+ | involves: C57BL/6 * DBA/2 | J:296328 | View | ||||
| supravalvular aortic stenosis | Elntm1Dyl/Eln+ | B6.129-Elntm1Dyl | J:86535 | View | ||||
| supravalvular aortic stenosis | Elntm1Dyl/Eln+ | involves: 129S1/Sv * 129X1/SvJ * C57BL/6J | J:51109 | View | ||||
| | aortic aneurysm | Atp7aMo-blo/Atp7a+ | Not Specified | J:5516 | View | |||
| aortic aneurysm | Atp7aMo-blo/Y | Not Specified | J:5516, J:15796 | View | ||||
| aortic aneurysm | Klf15tm1Jain/Klf15tm1Jain | B6.129X1-Klf15tm1Jain | J:167880 | View | ||||
| aortic dissection |
Best3tm1.1Zhoj/Best3tm1.1Zhoj Tg(Tagln-cre)1Her/0 |
involves: C57BL/6 * SJL | J:338981 | View | ||||
| aortic valve disease | Adamts19tm4a(EUCOMM)Wtsi/Adamts19tm4a(EUCOMM)Wtsi | C57BL/6N-Adamts19tm4a(EUCOMM)Wtsi | J:287334 | View | ||||
| aortic valve disease | Adamts19tm4b(EUCOMM)Wtsi/Adamts19tm4b(EUCOMM)Wtsi | B6N(Cg)-Adamts19tm4b(EUCOMM)Wtsi | J:287334 | View | ||||
| aortic valve disease | Egfrwa2/Egfrwa2 | involves: C57BL/6 | J:241813 | View | ||||
| aortic valve disease | Egfrwa2/Egfrwa2 | STOCK Egfrwa2 | J:60750 | View | ||||
| aortic valve disease | Elntm1Dyl/Eln+ | involves: 129S1/Sv * 129X1/SvJ * C57BL/6 | J:184494 | View | ||||
| aortic valve disease | Hey2tm1Kkb/Hey2tm1Kkb | involves: 129S7/SvEvBrd * C57BL/6 | J:216895 | View | ||||
| aortic valve disease | Nos3tm1Unc/Nos3tm1Unc | B6.129P2-Nos3tm1Unc/J | J:103340 | View | ||||
| aortic valve disease | Rbpjtm1Kyo/Rbpj+ | involves: 129S2/SvPas * CD-1 | J:187551 | View | ||||
| aortic valve stenosis | Tnftm2Gkl/Tnf+ | involves: 129S/SvEv * C57BL/6J | J:264147 | View | ||||
| coronary artery disease | Kcnj8tm1Sse/Kcnj8tm1Sse | involves: 129S1/Sv * 129X1/SvJ * C57BL/6 | J:76195 | View | ||||
| essential hypertension | Elntm1Dyl/Eln+ | B6.129-Elntm1Dyl | J:86535 | View | ||||
| essential hypertension | Gata5tm1.2Nemr/Gata5tm1.2Nemr | Not Specified | J:227997 | View | ||||
| hypertension | Nppatm1Unc/Nppa+ | involves: 129P2/OlaHsd * C57BL/6J | J:76312 | View | ||||
| hypertension | Nppatm1Unc/Nppatm1Unc | involves: 129P2/OlaHsd * C57BL/6 | J:76312 | View | ||||
| Marfan syndrome | Mus81tm1Esse/Mus81tm1Esse | involves: 129P2/OlaHsd * C57BL/6 | J:133703 | View | ||||
| persistent fetal circulation syndrome | Nos3tm1Unc/Nos3tm1Unc | B6.129P2-Nos3tm1Unc/J | J:98913 | View | ||||
| persistent fetal circulation syndrome |
Ptentm1Hwu/Ptentm1Hwu Twist2tm1.1(cre)Dor/Twist2+ |
B6.129-Twist2tm1.1(cre)Dor Ptentm1Hwu | J:192736 | View | ||||
| pre-eclampsia | Apelatm1.2Brre/Apelatm1.2Brre | B6(Cg)-Apelatm1.2Brre | J:244834 | View | ||||
| pre-eclampsia | Asb4tm1.2Cpat/Asb4tm1.2Cpat | involves: 129/SvEv | J:238841 | View | ||||
| pre-eclampsia | Cdkn1ctm1Kat/Cdkn1c+ | involves: 129P2/OlaHsd | J:102331 | View | ||||
| pre-eclampsia | Cdkn1ctm1Kat/Cdkn1ctm1Kat | involves: 129P2/OlaHsd | J:102331 | View | ||||
| pre-eclampsia | Comttm1Kara/Comttm1Kara | involves: 129S4/SvJaeSor | J:137276 | View | ||||
| pre-eclampsia | Ido1tm1.1Mkks/Ido1tm1.1Mkks | B6.Cg-Ido1tm1.1Mkks | J:229059 | View | ||||
| pre-eclampsia |
Notch2tm3Grid/Notch2tm3Grid Tg(Tpbpa-cre,-EGFP)5Jcc/0 |
involves: 129S1/Sv | J:173527 | View | ||||
| pre-eclampsia | Ptgs1tm1Fun/Ptgs1tm1Fun | involves: 129S6/SvEvTac * C57BL/6 | J:97351 | View | ||||
| pulmonary hypertension | Cavin1tm1Pfp/Cavin1tm1Pfp | B6.129S6-Cavin1tm1Pfp/J | J:217258 | View | ||||
| | coronary artery disease |
Apoetm1Unc/Apoetm1Unc Scarb1tm1Kri/Scarb1tm1Kri |
involves: 129P2/OlaHsd * 129S2/SvPas * BALB/c * C57BL/6 | J:201999 | View | |||
| Additional Complex Models | aortic valve disease |
Apobtm2Sgy/Apobtm2Sgy Ldlrtm1Her/Ldlrtm1Her Tg(Ins-Igf2)1Fbos/? |
involves: 129S7/SvEvBrd * C57BL/6 * C57BL/6J * SJL | J:227165 | View | |||
| coronary artery disease | Abcc9tm1Cfb/Abcc9tm1Cfb | Not Specified | J:78066 | View | ||||
| pre-eclampsia |
Adatm1Mw/Adatm1Mw Tg(Afp-ADA)#Xiay/0 |
involves: 129S7/SvEvBrd * C3H/HeJ * C57BL/6J | J:234143 | View | ||||
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No similarity to the expected human disease phenotype was found.
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| Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
| NOT Models | coronary artery disease |
Apoetm1Unc/Apoetm1Unc Svep1em1Nost/Svep1em1Nost |
involves: 129P2/OlaHsd * C57BL/6 | J:304349 | View | |||
| essential hypertension | Tnfrsf1btm1Imx/Tnfrsf1btm1Imx | involves: 129S7/SvEvBrd * C57BL/6 | J:45147 | View | ||||
| Marfan syndrome | Fbn1tm3.2Lysa/Fbn1+ | Not Specified | J:181493 | View | ||||
| Marfan syndrome | Fbn1tm3.2Lysa/Fbn1tm3.2Lysa | Not Specified | J:181493 | View | ||||
| Moyamoya disease | Rnf213tm1.1Mfuji/Rnf213tm1.1Mfuji | involves: C57BL/6 | J:229422 | View | ||||