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All mouse models of medulloblastoma with phenotypic similarity to the human disease
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| Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
 | medulloblastoma |
Cdkn1btm1Mlf/Cdkn1b+ Ptch1tm1Mps/Ptch1+ |
involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ * C57BL/6 | J:205254 | View | |||
| medulloblastoma |
Cdkn1btm1Mlf/Cdkn1btm1Mlf Ptch1tm1Mps/Ptch1+ |
involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ * C57BL/6 | J:205254 | View | ||||
| medulloblastoma |
Cdkn2ctm1Bbd/Cdkn2ctm1Bbd Ptch1tm1Mps/Ptch1+ |
involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ | J:102702 | View | ||||
| medulloblastoma |
Gt(ROSA)26Sortm1(Smo/EYFP)Amc/Gt(ROSA)26Sortm1(Smo/EYFP)Amc Olig2tm2(TVA,cre)Rth/Olig2+ |
involves: 129 * 129X1/SvJ | J:139574 | View | ||||
| medulloblastoma |
Gt(ROSA)26Sortm1(Smo/EYFP)Amc/Gt(ROSA)26Sortm1(Smo/EYFP)Amc Tg(Atoh1-cre/Esr1*)14Fsh/0 |
involves: 129X1/SvJ * FVB/N | J:139574 | View | ||||
| medulloblastoma |
Gt(ROSA)26Sortm1(Smo/EYFP)Amc/Gt(ROSA)26Sortm1(Smo/EYFP)Amc Tg(GFAP-cre)25Mes/0 |
involves: 129X1/SvJ * FVB/N | J:139574 | View | ||||
| medulloblastoma |
Gt(ROSA)26Sortm1(Smo/EYFP)Amc/Gt(ROSA)26Sortm1(Smo/EYFP)Amc Tlx3tm1(cre)Qima/Tlx3+ |
involves: 129X1/SvJ | J:139574 | View | ||||
| medulloblastoma |
Ptch1tm1Bjw/Ptch1tm1Bjw Tg(Atoh1-cre)1Bfri/0 |
involves: 129T2/SvEms * C57BL/6 * CBA | J:139573 | View | ||||
| medulloblastoma |
Ptch1tm1Bjw/Ptch1tm1Bjw Tg(Atoh1-cre/Esr1*)14Fsh/0 |
involves: 129T2/SvEms * FVB/N | J:139573 | View | ||||
| medulloblastoma |
Ptch1tm1Bjw/Ptch1tm1Bjw Tg(GFAP-cre)25Mes/0 |
involves: 129T2/SvEms * FVB/N | J:139573 | View | ||||
| medulloblastoma | Ptch1tm1Mps/Ptch1+ | involves: 129S1/Sv * 129X1/SvJ | J:144811 | View | ||||
| medulloblastoma |
Ptch1tm1Mps/Ptch1+ Ptch2tm1Pmc/Ptch2+ |
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 | J:112118 | View | ||||
| medulloblastoma |
Ptch1tm1Mps/Ptch1+ Ptch2tm1Pmc/Ptch2tm1Pmc |
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 | J:112118 | View | ||||
| medulloblastoma |
Ptch1tm1Mps/Ptch1+ Tg(Atoh1-GFP)1Jejo/? |
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2 | J:144811 | View | ||||
| medulloblastoma |
Ptch1tm1Mps/Ptch1+ Trp53tm1Tyj/Trp53tm1Tyj |
involves: 129 * 129S2/SvPas * C57BL/6 | J:67452 | View | ||||
| medulloblastoma | Ptch1tm1Zim/Ptch1+ | involves: 129 * CD-1 | J:79666 | View | ||||
| medulloblastoma |
Tg(GFAP-tTA)67Pop/0 Tg(tetO-Ifng)184Pop/0 |
B6.Cg-Tg(GFAP-tTA)67Pop Tg(tetO-Ifng)184Pop | J:94092 | View | ||||
| medulloblastoma |
Tg(GFAP-tTA)67Pop/0 Tg(tetO-Ifng)184Pop/0 |
involves: 129S/SvEv * C57BL/6 * DBA/2 | J:94092 | View | ||||
| medulloblastoma | Tg(Neurod2-Smo*A1)199Jols/0 | C57BL/6-Tg(Neurod2-Smo*A1)199Jols | J:93861 | View | ||||
| medulloblastoma | Tg(Neurod2-Smo*A1)199Jols/0 | involves: C57BL/6 | J:221990 | View | ||||
| medulloblastoma | Tg(Neurod2-Smo*A1)199Jols/Tg(Neurod2-Smo*A1)199Jols | C57BL/6-Tg(Neurod2-Smo*A1)199Jols | J:189258 | View | ||||
| medulloblastoma | Tg(Neurod2-Smo*A2)#Jols/0 | C57BL/6-Tg(Neurod2-Smo*A2)#Jols | J:189258 | View | ||||
 | medulloblastoma |
Brca2tm1Brn/Brca2tm1Brn Trp53tm1Tyj/Trp53+ Tg(Nes-cre)1Kln/0 |
involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6 * SJL | J:144617 | View | |||
| medulloblastoma |
Brca2tm1Brn/Brca2tm1Brn Trp53tm1Tyj/Trp53tm1Tyj Tg(Nes-cre)1Kln/0 |
involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6 * SJL | J:144617 | View | ||||
| medulloblastoma |
SufuGt(XB699)Byg/Sufu+ Trp53tm1Tyj/Trp53tm1Tyj |
involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6 | J:173443 | View | ||||
| Transgenes and Other Mutations | medulloblastoma |
Tg(Slc1a2-tTA)#Waw/0 Tg(tetO-MYCN,-luc)#Waw/0 |
involves: FVB/NJ | J:160518 | View | |||
| medulloblastoma |
Tg(Slc1a2-tTA)#Waw/0 Tg(tetO-MYCN,-luc)#Waw/Tg(tetO-MYCN,-luc)#Waw |
involves: FVB/NJ | J:160518 | View | ||||
| medulloblastoma | Tg(tetO-TAg,CMV-rtTA)123Yihu/0 | involves: FVB/N | J:141623 | View | ||||
| Additional Complex Models | medulloblastoma |
Cdkn2ctm1Bbd/Cdkn2c+ Trp53tm1Tyj/Trp53tm1Tyj |
involves: 129S1/Sv * 129S2/SvPas * C57BL/6 | J:102702 | View | |||
| medulloblastoma |
Cdkn2ctm1Bbd/Cdkn2ctm1Bbd Trp53tm1Brn/Trp53tm1Tyj Tg(Nes-cre)1Kln/0 |
involves: 129P2/OlaHsd * 129S1/Sv * 129S2/SvPas * C57BL/6 * SJL | J:102702 | View | ||||
| medulloblastoma |
Cdkn2ctm1Bbd/Cdkn2ctm1Bbd Trp53tm1Tyj/Trp53tm1Tyj |
involves: 129S1/Sv * 129S2/SvPas * C57BL/6 | J:102702 | View | ||||
| medulloblastoma |
Lig4tm1Icrf/Lig4tm1Icrf Trp53tm1Tyj/Trp53tm1Tyj |
either: (involves: 129P2/OlaHsd * 129S2/SvPas) or (involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ) | J:173443 | View | ||||
| medulloblastoma |
Ptentm2Mak/Ptentm2Mak Trp53tm1Brn/Trp53tm1Brn Tg(Nes-cre/ERT2,-ALPP)1Sbk/0 |
involves: 129P2/OlaHsd | J:237990 | View | ||||
| medulloblastoma |
Rag1tm1Mom/Rag1tm1Mom Trp53tm1Brd/Trp53tm1Brd Xrcc5tm1Dbr/Xrcc5tm1Dbr |
involves: 129S7/SvEvBrd * C57BL | J:141515 | View | ||||
| medulloblastoma |
Rb1tm2Brn/Rb1tm2Brn Trp53tm1Brd/Trp53tm1Brd Tg(Gfap-cre)2Brn/0 |
involves: 129 * 129S7/SvEvBrd * FVB/N | J:61961 | View | ||||
| medulloblastoma |
Rb1tm2Brn/Rb1tm2Brn Trp53tm1Brn/Trp53tm1Brn Tg(Gfap-cre)2Brn/0 |
involves: 129P2/OlaHsd * FVB/N | J:61961 | View | ||||
| medulloblastoma |
Trp53tm1Brd/Trp53tm1Brd Xrcc4tm2.1Fwa/Xrcc4tm2Fwa Tg(Nes-cre)1Kln/0 |
involves: 129S6/SvEvTac * 129S7/SvEvBrd * C57BL/6 * SJL | J:109585 | View | ||||