Excel File Text File All mouse models of autoimmune disease of endocrine system with phenotypic similarity to the human disease
        Disease Term Allelic Composition Genetic Background Reference Phenotypes
      autoimmune polyendocrine syndrome type 1 Airetm1.1Doi/Airetm1.1Doi B6.129S2-Airetm1.1Doi/Doi J:107432 View
autoimmune polyendocrine syndrome type 1 Airetm1.1Doi/Airetm1.1Doi C.129S2-Airetm1.1Doi/Doi J:107432 View
autoimmune polyendocrine syndrome type 1 Airetm1.1Doi/Airetm1.1Doi involves: 129S2/SvPas * C57BL/6 J:83422 View
autoimmune polyendocrine syndrome type 1 Airetm1.1Doi/Airetm1.1Doi NOD.129S2(B6)-Airetm1.1Doi/Doi J:107432 View
autoimmune polyendocrine syndrome type 1 Airetm1.1Doi/Airetm1.1Doi SJL.129S2-Airetm1.1Doi/Doi J:107432 View
autoimmune polyendocrine syndrome type 1 Airetm1Mmat/Airetm1Mmat B6.Cg-Airetm1Mmat J:96580 View
autoimmune polyendocrine syndrome type 1 Airetm1Mmat/Airetm1Mmat C.Cg-Airetm1Mmat J:96580 View
autoimmune polyendocrine syndrome type 1 Airetm1Mmat/Airetm1Mmat involves: C57BL/6 * CBA J:96580 View
autoimmune polyendocrine syndrome type 1 Airetm1Pltn/Airetm1Pltn involves: 129S4/SvJae * C57BL/6 J:77873 View
type 1 diabetes mellitus Cd38tm1Lnd/Cd38tm1Lnd NOD.129P2(B6)-Cd38tm1Lnd/LtJ J:108097 View
type 1 diabetes mellitus Gad2tm1Miya/Gad2tm1Miya NOD.129P2-Gad2tm1Miya J:88785 View
type 1 diabetes mellitus H2g7/H2g7
Ins2tm1Jja/Ins2tm1Jja
Rag1tm1Mom/Rag1tm1Mom
Tg(TcraBDC12-4.1)10Jos/0
Tg(TcrbBDC12-4.1)82Gse/0		 involves: 129S2/SvPas * 129S7/SvEvBrd * C57BL/6 * FVB * NOD J:111874 View
type 1 diabetes mellitus Il1r1tm1Roml/Il1r1tm1Roml NOD.Cg-Il1r1tm1Roml J:87251 View
type 1 diabetes mellitus Ins1tm1Jja/Ins1tm1Jja
Tg(Ins2*Y16A)1Ell/0		 NOD.Cg-Ins1tm1Jja Tg(Ins2*Y16A)1Ell J:98583 View
type 1 diabetes mellitus Ins2Akita/Ins2Akita C.B6N-Ins2Akita J:198186 View
type 1 diabetes mellitus Ins2Akita/Ins2Akita
Itga1tm1Gdnr/Itga1tm1Gdnr		 C.Cg-Ins2Akita Itga1tm1Gdnr J:198186 View
type 1 diabetes mellitus Ins2tm1Jja/Ins2tm1Jja NOD.129S2-Ins2tm1Jja J:85309 View
type 1 diabetes mellitus Ptprn2tm1Aln/Ptprn2tm1Aln involves: 129S4/SvJae * C57BL/6N * NOD/LtJ J:81889 View
type 1 diabetes mellitus Tg(H2-Ea-Ins2)1Wehi/0 NOD/ShiLtJWehi-Tg(H2-Ea-Ins2)1Wehi J:100251 View
      type 1 diabetes mellitus Agertm1.1Hyam/Agertm1.1Hyam
Tg(Ins2-Nos2)40Okam/0		 involves: 129P2/OlaHsd * C57BL/6 * CD-1 * DBA/2 J:116040 View
type 1 diabetes mellitus Cdk4tm1Bbd/Cdk4tm1Bbd involves: 129S1/Sv * 129X1/SvJ * ICR J:54534 View
type 1 diabetes mellitus E2f1tm1Meg/E2f1tm1Meg NOD.Cg-E2f1tm1Meg J:93708 View
type 1 diabetes mellitus Faslpr/Faslpr
Tg(Ins2-Fasl)24Ach/0		 NOD.Cg-Faslpr Tg(Ins2-Fasl)24Ach J:81416 View
type 1 diabetes mellitus Ifngtm1Ts/Ifngtm1Ts NOD.129S7(B6)-Ifngtm1Ts/DvsJ J:72818 View
type 1 diabetes mellitus Ifngtm1Ts/Ifngtm1Ts NOD.Cg-Ifngtm1Ts Prkdcscid J:72818 View
type 1 diabetes mellitus Ifngr2tm1Pbro/Ifngr2tm1Pbro NOD.129S1-Ifngr2tm1Pbro J:72818 View
type 1 diabetes mellitus Ighmtm1Cgn/Ighm+ NOD.129S2-Ighmtm1Cgn J:37287 View
type 1 diabetes mellitus Ighmtm1Cgn/Ighm+
Tg(Igh-6/Igh-V281)3Jwt/0		 NOD.Cg-Ighmtm1Cgn Tg(Igh-6/Igh-V281)3Jwt J:91865 View
type 1 diabetes mellitus Ighmtm1Cgn/Ighmtm1Cgn
Tg(Igh-VB1-8/Igh-6m)1Mjsk/?		 NODCaj.Cg-Ighmtm1Cgn Tg(Igh-VB1-8/Igh-6m)1Mjsk/FswJ J:93190 View
type 1 diabetes mellitus Il4tm1Cgn/Il4tm1Cgn either: NOD.129-Il4tm1Cgn or (involves: 129 * NOD) J:85924 View
type 1 diabetes mellitus Il4tm1Cgn/Il4tm1Cgn
Tg(TcraBDC2.5,TcrbBDC2.5)1Doi/0		 NOD.Cg-Il4tm1Cgn Tg(TcraBDC2.5,TcrbBDC2.5)1Doi J:85924 View
type 1 diabetes mellitus Irak3tm1Flv/Irak3tm1Flv NOD.129S1(B6)-Irak3tm1Flv J:229884 View
type 1 diabetes mellitus Mbd2tm1Bh/Mbd2tm1Bh NOD.129P2(B6)-Mbd2tm1Bh J:323838 View
type 1 diabetes mellitus Pdx1tm1Cvw/Pdx1tm4Cvw
Tg(Ins2-cre)25Mgn/0		 involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6 * DBA J:130389 View
type 1 diabetes mellitus Prf1tm1Clrk/Prf1tm1Clrk involves: 129S7/SvEvBrd * BALB/c * NOD J:64051 View
type 1 diabetes mellitus Prf1tm1Clrk/Prf1tm1Clrk
Tg(INS-Il10)#Sar/0		 involves: 129S7/SvEvBrd * BALB/c * NOD J:64051 View
type 1 diabetes mellitus Selltm1Flv/Sell+ involves: C57BL/6 * NOD J:88974 View
type 1 diabetes mellitus Selltm1Flv/Sell+ NOD.Cg-Selltm1Flv J:88974 View
type 1 diabetes mellitus Selltm1Flv/Selltm1Flv involves: C57BL/6 * NOD J:88974 View
type 1 diabetes mellitus Selltm1Flv/Selltm1Flv NOD.Cg-Selltm1Flv J:88974 View
type 1 diabetes mellitus Senp1tm1Wami/Senp1tm1Wami
Tg(Fabp4-cre)#Abel/0		 B6.Cg-Senp1tm1Wami Tg(Fabp4-cre)#Abel J:228009 View
type 1 diabetes mellitus Stat4tm1Gru/Stat4+ NOD.129S2-Stat4tm1Gru J:90600 View
type 1 diabetes mellitus Stat4tm1Gru/Stat4tm1Gru C.129S2-Stat4tm1Gru J:106340 View
type 1 diabetes mellitus Stat4tm1Gru/Stat4tm1Gru
Tg(Ins2-GP)34-20Olds/0		 involves: 129S2/SvPas * BALB/c * C57BL/6 J:107047 View
type 1 diabetes mellitus Stat4tm1Gru/Stat4tm1Gru
Tg(Ins2-NP)25-3Olds/0		 involves: 129S2/SvPas * BALB/c * C57BL/6 J:107047 View
type 1 diabetes mellitus Tg(H2-Ea-G6pc2)69Tkay/? NOD-Tg(H2-Ea-G6pc2)69Tkay J:117352 View
type 1 diabetes mellitus Tg(Igh-6/Igh-V125)2Jwt/0
Tg(Igk-C/Igk-V125)1Jwt/0		 NOD.B6-Tg(Igh-6/Igh-V125)2Jwt Tg(Igk-C/Igk-V125)1Jwt J:91865 View
type 1 diabetes mellitus Tg(Igh-6/Igh-V281)3Jwt/0 NOD.B6-Tg(Igh-6/Igh-V281)3Jwt J:91865 View
type 1 diabetes mellitus Tg(Ins2-Fas*I246N)1Ach/0
Tg(Ins2-Fasl)24Ach/0		 NOD-Tg(Ins2-Fas*I246N)1Ach Tg(Ins2-Fasl)24Ach J:81416 View
type 1 diabetes mellitus Tg(Ins2-Fasl)24Ach/0 NOD-Tg(Ins2-Fasl)24Ach/J J:78679 View
type 1 diabetes mellitus Tg(Ins2-Nos2)31Okam/0 involves: C57BL/6 * CD-1 * DBA/2 J:45520 View
type 1 diabetes mellitus Tg(Ins2-Nos2)40Okam/0 involves: 129P2/OlaHsd * C57BL/6 * CD-1 * DBA/2 J:116040 View
type 1 diabetes mellitus Tg(Ins2-Nos2)40Okam/0 involves: C57BL/6 * CD-1 * DBA/2 J:4552 View
type 1 diabetes mellitus Tg(Ins2-Nos2)40Okam/0
Tg(Kdr-AGER)102Hyam/0		 involves: C57BL/6J * CBA/J * CD-1 * DBA/2 J:70495 View
type 1 diabetes mellitus Tnfsf4tm1Shr/Tnfsf4tm1Shr NOD.129S4-Tnfsf4tm1Shr J:86926 View
type 1 diabetes mellitus 2 Apobtm2Sgy/Apobtm2Sgy
Ldlrtm1Her/Ldlrtm1Her
Tg(Ins-Igf2)1Fbos/?		 involves: 129S7/SvEvBrd * C57BL/6 * C57BL/6J * SJL J:227165 View
type 1 diabetes mellitus 2 Tg(Ins-Igf2)1Fbos/0 involves: C57BL/6 * C57BLKs/J * SJL J:141527 View
type 1 diabetes mellitus 2 Tg(Ins-Igf2)1Fbos/0 involves: C57BL/6 * SJL J:141527 View
type 1 diabetes mellitus 7 Neurod1tm1Mjts/Neurod1tm1Mjts involves: 129S7/SvEvBrd * C57BL/6 J:43010 View
      type 1 diabetes mellitus Cd80tm1Shr/Cd80tm1Shr
Cd86tm2Shr/Cd86tm2Shr		 involves: 129S4/SvJae * NOD J:61905 View
type 1 diabetes mellitus H2-Ab1b-tm1Gru/H2-Ab1b-tm1Gru
Tg(HLA-DQA1,HLA-DQB1)1Dv/0
Tg(HLA-DRB1)31Dmz/0
Tg(Ins2-CD80)3B7Flv/0		 involves: 129S2/SvPas * C57BL/6 * C57BL/10SnJ * CBA * SJL J:68641 View
type 1 diabetes mellitus H2-Ab1b-tm1Gru/H2-Ab1b-tm1Gru
Tg(HLA-DQA1,HLA-DQB1)1Dv/0
Tg(Ins2-CD80)3B7Flv/0		 B6.Cg-H2-Ab1b-tm1Gru Tg(HLA-DQA1,HLA-DQB1)1Dv Tg(Ins2-CD80)3B7Flv J:59245 View
type 1 diabetes mellitus H2-Ab1b-tm1Gru/H2-Ab1b-tm1Gru
Tg(HLA-DRB1)31Dmz/0
Tg(Ins2-CD80)3B7Flv/0		 involves: 129S2/SvPas * C57BL/6 * CBA * SJL J:68641 View
type 1 diabetes mellitus Tg(Ins1-Cd80)378Psoh/0
Tg(Ins2-GP)#Psoh/0
Tg(TcrLCMV)327Sdz/0		 involves: C57BL/6 * DBA/2 * FVB/N J:209714 View
Transgenes and
Other Mutations		     type 1 diabetes mellitus B2mtm1Unc/B2mtm1Unc
Tg(HLA-A/H2-D/B2M)1Dvs/0		 NOD.Cg-B2mtm1Unc Tg(HLA-A/H2-D/B2M)1Dvs J:121685 View
type 1 diabetes mellitus Cd4tm1Knw/Cd4tm1Knw
Tg(TcraAI4)1Dvs/0
Tg(TcrbAI4)1Dvs/0		 NOD.Cg-Cd4tm1Knw Tg(TcraAI4)1Dvs Tg(TcrbAI4)1Dvs J:93553 View
type 1 diabetes mellitus Fastm1Vbo/Fastm1Vbo
Tg(Ins2-cre)25Mgn/0
Tg(Ins2-HA)165Bri/0
Tg(Tcra/Tcrb)1Vbo/0		 Not Specified J:85985 View
type 1 diabetes mellitus H2g7/H2g7
Rag1tm1Mom/Rag1tm1Mom
Tg(TcraBDC12-4.1)10Jos/0
Tg(TcrbBDC12-4.1)82Gse/0		 involves: 129S7/SvEvBrd * C57BL/6 * FVB * NOD J:111874 View
type 1 diabetes mellitus H2g7/H2q
Rag1tm1Mom/Rag1tm1Mom
Tg(TcraBDC12-4.1)10Jos/0
Tg(TcrbBDC12-4.1)82Gse/0		 involves: 129S7/SvEvBrd * C57BL/6 * FVB * NOD J:111874 View
type 1 diabetes mellitus Prkdcscid/Prkdcscid
Tg(TcraAI4)1Dvs/0
Tg(TcrbAI4)1Dvs/0		 NOD.Cg-Prkdcscid Tg(TcraAI4)1Dvs Tg(TcrbAI4)1Dvs J:93553 View
type 1 diabetes mellitus Rag1tm1Mom/Rag1tm1Mom
Tg(TcraAI4)1Dvs/0
Tg(TcrbAI4)1Dvs/0		 NOD.Cg-Rag1tm1Mom Tg(TcraAI4)1Dvs Tg(TcrbAI4)1Dvs/Dvs J:94192 View
type 1 diabetes mellitus Rag1tm1Mom/Rag1tm1Mom
Tg(TcraBDC12-4.1)10Jos/0
Tg(TcrbBDC12-4.1)82Gse/0		 involves: 129S7/SvEvBrd * C57BL/6 * FVB * NOD J:111874 View
type 1 diabetes mellitus Tg(Cryaa-TAg,Ins2-CALM1)26Ove/0 FVB(Cg)-Tg(Cryaa-Tag,Ins2-CALM1)26Ove/PneJ J:97926 View
type 1 diabetes mellitus Tg(Cryaa-TAg,Ins2-CALM1)26Ove/0 FVB-Tg(Cryaa-TAg,Ins2-CALM1)26Ove J:94602 View
type 1 diabetes mellitus Tg(H2-Ead)12Lt/0 NOD/ShiLt-Tg(H2-Ead)12Lt J:36435 View
type 1 diabetes mellitus Tg(HLA-A/H2-D/B2M)1Dvs/0 NOD/ShiLtDvs-Tg(HLA-A/H2-D/B2M)1Dvs J:121685 View
type 1 diabetes mellitus Tg(IghelMD4)4Ccg/Tg(IghelMD4)4Ccg NOD.B6-Tg(IghelMD4)4Ccg/DvsJ J:80859 View
type 1 diabetes mellitus Tg(Ins1-Cat,Tyr)25Pne/0 involves: FVB J:59725 View
type 1 diabetes mellitus Tg(Ins1-Cat,Tyr)25Pne/0 NOD.FVB-Tg(Ins1-Cat,Tyr)25Pne J:108415 View
type 1 diabetes mellitus Tg(Ins2*Y16A)3Ell/0 NOD-Tg(Ins2*Y16A)3Ell J:98583 View
type 1 diabetes mellitus Tg(Ins2-CD80)3B7Flv/? involves: C57BL/6 * CBA/Ca * NOD/Caj J:26618 View
type 1 diabetes mellitus Tg(Ins2-GP)34-20Olds/0 involves: BALB/c * C57BL/6 J:81287 View
type 1 diabetes mellitus Tg(Ins2-HBEGF)5Rin/? C57BL/6-Tg(Ins2-HBEGF)5Rin J:204420 View
type 1 diabetes mellitus Tg(Ins2-NP)25-3Olds/0 involves: BALB/c * C57BL/6 J:81284 View
type 1 diabetes mellitus Tg(INS-MT2A,Tyr)1Pne/0 FVB-Tg(INS-MT2A,Tyr)1Pne J:100251 View
type 1 diabetes mellitus Tg(INS-MT2A,Tyr)1Pne/0 NOD.FVB-Tg(INS-MT2A,Tyr)1Pne J:108415 View
type 1 diabetes mellitus Tg(INS-SOD2)3Pne/0 NOD.FVB-Tg(INS-SOD2)3Pne J:108415 View
type 1 diabetes mellitus Tg(TcraAI4)1Dvs/0 NOD-Tg(TcraAI4)1Dvs J:93553 View
type 1 diabetes mellitus Tg(TcraAI4)1Dvs/0
Tg(TcrbAI4)1Dvs/0		 NOD-Tg(TcraAI4)1Dvs Tg(TcrbAI4)1Dvs J:93553 View
type 1 diabetes mellitus Tg(TcraTcrbNY8.3)1Pesa/? involves: C57BL/6 * NOD * SJL J:44202 View
Additional
Complex
Models		     type 1 diabetes mellitus Casp1tm1Sesh/Casp1tm1Sesh
Casp4del/Casp4del		 NOD.129S2(B6)-Casp1tm1Sesh Casp4del/LtJ J:87250 View
type 1 diabetes mellitus Prkdcscid/Prkdcscid
Tg(INS-HBEGF*L148S*P149T)70Rin/0		 C.BKa-Prkdcscid Tg(INS-HBEGF*L148S*P149T)70Rin J:204420 View

       
No similarity to the expected human disease phenotype was found.
        Disease Term Allelic Composition Genetic Background Reference Phenotypes
NOT Models      type 1 diabetes mellitus B2mtm1Jae/B2mtm1Jae
Tg(B2m)1Rms/0
Tg(INS-cre)2Rms/0		 involves: 129S2/SvPas * NOD J:83635 View
type 1 diabetes mellitus B2mtm1Unc/B2mtm1Unc NOD.129P2-B2mtm1Unc J:17000 View
type 1 diabetes mellitus B2mtm1Unc/B2mtm1Unc
Ciitatm1Ccum/Ciitatm1Ccum		 NOD.Cg-B2mtm1Unc Ciitatm1Ccum J:107051 View
type 1 diabetes mellitus B2mtm1Unc/B2mtm1Unc
Tg(TcraAI4)1Dvs/0
Tg(TcrbAI4)1Dvs/0		 NOD.Cg-B2mtm1Unc Tg(TcraAI4)1Dvs Tg(TcrbAI4)1Dvs J:93553 View
type 1 diabetes mellitus Casp3tm1Mak/Casp3tm1Mak B6.129P2-Casp3tm1Mak J:97650 View
type 1 diabetes mellitus Cd4tm1Knw/Cd4tm1Knw NOD.Cg-Cd4tm1Knw J:93553 View
type 1 diabetes mellitus Ciitatm1Ccum/Ciitatm1Ccum NOD.129S2(B6)-Ciitatm1Ccum J:106081 View
type 1 diabetes mellitus Ctnna2tm1Mta/Ctnna2tm1Mta Not Specified J:83635 View
type 1 diabetes mellitus Faslpr/Faslpr NOD.MRL(B6)-Faslpr J:64051 View
type 1 diabetes mellitus H2-Ab1b-tm1Gru/H2-Ab1b-tm1Gru
Tg(CD2-CD4,HLA-DQA1,HLA-DQB1)1Ell/Tg(CD2-CD4,HLA-DQA1,HLA-DQB1)1Ell		 NOD.Cg-H2-Ab1b-tm1Gru Tg(CD2-CD4,HLA-DQA1,HLA-DQB1)1Ell J:87013 View
type 1 diabetes mellitus Icam1tm1Jcgr/Icam1tm1Jcgr
Tg(INS-Il10)#Sar/0		 NOD.Cg-Icam1tm1Jcgr Tg(INS-Il10)#Sar J:98583 View
type 1 diabetes mellitus Ighmtm1Cgn/Ighmtm1Cgn NOD.129S2-Ighmtm1Cgn J:37287 View
type 1 diabetes mellitus Ighmtm1Cgn/Ighmtm1Cgn NOD.129S2-Ighmtm1Cgn/DvsJ J:80859 View
type 1 diabetes mellitus Ighmtm1Cgn/Ighmtm1Cgn
Tg(IghelMD4)4Ccg/Tg(IghelMD4)4Ccg		 NOD.Cg-Ighmtm1Cgn Tg(IghelMD4)4Ccg/DvsJ J:80859 View
type 1 diabetes mellitus Ins1tm1Jja/Ins1tm1Jja NOD.129S2-Ins1tm1Jja J:85309 View
type 1 diabetes mellitus Ins1tm1Jja/Ins1tm1Jja
Ins2tm1Jja/Ins2tm1Jja
Tg(Ins2*Y16A)1Ell/0		 NOD.Cg-Ins1tm1Jja Ins2tm1Jja Tg(Ins2*Y16A)1Ell J:98583 View
type 1 diabetes mellitus Ins1tm1Jja/Ins1tm1Jja
Ins2tm1Jja/Ins2tm1Jja
Tg(Ins2*Y16A)3Ell/0		 NOD.Cg-Ins1tm1Jja Ins2tm1Jja Tg(Ins2*Y16A)3Ell J:98583 View
type 1 diabetes mellitus Parp1tm1Hsmm/Parp1tm1Hsmm involves: 129S4/SvJae J:53360 View
type 1 diabetes mellitus Stat4tm1Gru/Stat4tm1Gru NOD.129S2-Stat4tm1Gru J:90600 View
type 1 diabetes mellitus Tg(H2-Ead)5Lt/0 NOD/ShiLt-Tg(H2-Ead)5Lt J:36435 View
type 1 diabetes mellitus Tg(TcrbAI4)1Dvs/0 NOD-Tg(TcrbAI4)1Dvs J:93553 View
type 1 diabetes mellitus Tlr2tm1Aki/Tlr2tm1Aki NOD.129P2-Tlr2tm1Aki J:124334 View
type 1 diabetes mellitus 2 Hk2tm1Laak/Hk2+ involves: 129P2/OlaHsd * BALB/c * DBA/2 J:56644 View