Excel File Text File All mouse models of autoimmune disease of musculoskeletal system with phenotypic similarity to the human disease
        Disease Term Allelic Composition Genetic Background Reference Phenotypes
      psoriasis Tg(KRT5-Stat3*A661C*N663C)1Jdg/0 involves: FVB J:95458 View
psoriasis Tg(KRT14-Vegfa)3Dtm/0 FVB/N-Tg(KRT14-Vegfa)3Dtm J:92643 View
psoriasis 2 Card14em2Tshu/Card14+ involves: C57BL/6 J:289239 View
psoriasis 2 Card14em9Lutzy/Card14+ C57BL/6J-Card14em9Lutzy/J J:262723 View
rheumatoid arthritis TnfBpsm1/Tnf+ involves: C57BL/6 J:226052 View
rheumatoid arthritis TnfBpsm1/TnfBpsm1 involves: C57BL/6 J:226052 View
rheumatoid arthritis Tnftm1Gkl/Tnftm2Gkl involves: 129S/SvEv * C57BL/6 J:54056 View
rheumatoid arthritis Tnftm2Gkl/Tnf+ involves: 129S/SvEv * C57BL/6 J:54056 View
rheumatoid arthritis Tnftm2Gkl/Tnf+ involves: 129S/SvEv * C57BL/6J J:264147 View
rheumatoid arthritis Tnftm2Gkl/Tnftm2Gkl involves: 129S/SvEv * C57BL/6 J:54056 View
systemic lupus erythematosus C4btm1Crr/C4btm1Crr involves: 129S4/SvJae * C57BL/6J J:111811 View
systemic lupus erythematosus Ccr2tm1Blck/Ccr2tm1Blck
Faslpr/Faslpr
MRL.Cg-Ccr2tm1Blck Faslpr J:113343 View
systemic lupus erythematosus Dnase1tm1Tmo/Dnase1tm1Tmo involves: 129P2/OlaHsd * C57BL/6 J:62549 View
systemic lupus erythematosus Dnase1tm2092.1Arte/Dnase1tm2092.1Arte involves: C57BL/6 J:277126 View
systemic lupus erythematosus Faslpr/Faslpr MRL/Mp-Faslpr J:27634, J:28885, J:108760, J:131138 View
systemic lupus erythematosus Faslpr/Faslpr
Igh-Jtm2(3H9-VDJ*)Mwg/Igh-J+
MRL.Cg-Faslpr Igh-Jtm2(3H9-VDJ*)Mwg J:131138 View
systemic lupus erythematosus Faslpr/Faslpr
Tlr9tm1Aki/Tlr9tm1Aki
MRL.Cg-Tlr9tm1Aki Faslpr J:113557 View
systemic lupus erythematosus Faslpr/Faslpr
Tnfrsf9tm1Byk/Tnfrsf9tm1Byk
MRL.Cg-Tnfrsf9tm1Byk Faslpr J:120559 View
systemic lupus erythematosus Fcgr2btm1Ttk/Fcgr2btm1Ttk B6.129S4-Fcgr2btm1Ttk J:64152 View
systemic lupus erythematosus Fcgr2btm1Ttk/Fcgr2btm1Ttk
Traf3ip2tm1Sbn/Traf3ip2+
involves: 129 * 129S4/SvJae * C57BL/6 J:191090 View
systemic lupus erythematosus Pdcd1tm1Hon/Pdcd1tm1Hon B6.129S2-Pdcd1tm1Hon J:78802 View
systemic lupus erythematosus Pdcd1tm1Hon/Pdcd1tm1Hon involves: 129S2/SvPas * C57BL/6 J:50688 View
      alopecia areata Cchcr1em1Aoka/Cchcr1em1Aoka C57BL/6NJcl-Cchcr1em1Aoka J:309941 View
cutaneous lupus erythematosus Trex1tm1Tld/Trex1tm1Tld involves: 129P2/OlaHsd * C57BL/6J J:243357 View
Lambert-Eaton myasthenic syndrome Cacna1atg-rol/Cacna1atg-rol involves: C57BL/6 * SIII J:164115 View
pemphigus vulgaris Dsg3bal-Pas/Dsg3bal-Pas 129S2.Cg-Dsg3bal-Pas J:46865 View
pemphigus vulgaris Dsg3bal/Dsg3bal C57BL/6J-Dsg3bal/J J:42792 View
pemphigus vulgaris Dsg3tm1Stan/Dsg3tm1Stan involves: 129X1/SvJ * C57BL/6J J:40804 View
psoriasis Arpc4tm1c(EUCOMM)Wtsi/Arpc4tm1c(EUCOMM)Wtsi
Krt14tm1(cre)Wbm/Krt14+
B6.Cg-Arpc4tm1c(EUCOMM)Wtsi Krt14tm1(cre)Wbm J:253986 View
psoriasis Itgb2tm1Bay/Itgb2tm1Bay involves: 129S7/SvEvBrd * C57BL/6J * PL/J J:32126, J:84126 View
psoriasis Itgb2tm1Bay/Itgb2tm1Bay involves: 129S7/SvEvBrd * PL/J J:32126, J:109598 View
psoriasis Itgb2tm1Bay/Itgb2tm2Bay involves: 129S7/SvEvBrd * C57BL/6J * PL/J J:84126 View
psoriasis Itgb2tm1Bay/Itgb2tm2Bay PL.129S7-Itgb2tm1Bay Itgb2tm2Bay J:84126 View
psoriasis Itgb2tm2Bay/Itgb2tm2Bay involves: 129S7/SvEvBrd * PL/J J:84126 View
psoriasis Sptlc2tm1Yhir/Sptlc2tm1Yhir
Tg(KRT5-cre)1Tak/0
involves: C3H * C57BL/6 J:202388 View
psoriasis Tg(KRT5-rtTA)#Glk/0
Tg(tetO-S100a7a)#Yus/0
involves: FVB/N J:168000 View
psoriasis Ttc7fsn/Ttc7fsn involves: A/J * BALB/cByJ J:14506 View
rheumatoid arthritis Dnase2atm1Osa/Dnase2atm1Osa
Ifnar1tm1Agt/Ifnar1tm1Agt
involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6 J:114982, J:238323 View
rheumatoid arthritis Dnase2atm1Osa/Dnase2atm2Osa
Tg(Mx1-cre)1Cgn/0
involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6 * CBA J:114982 View
rheumatoid arthritis Il6sttm1Thir/Il6sttm1Thir involves: 129 * C57BL/6 J:133059 View
rheumatoid arthritis Mmp14tm1Hbh/Mmp14tm1Hbh involves: 129P2/OlaHsd * Black Swiss J:57969 View
rheumatoid arthritis Zap70m1Saka/Zap70m1Saka involves: BALB/c J:86607 View
rheumatoid arthritis Zfp36tm1Pjb/Zfp36tm1Pjb B6.Cg-Zfp36tm1Pjb J:214114 View
systemic lupus erythematosus Atg5tm1Myok/Atg5tm1Myok
Lyz2tm1(cre)Ifo/Lyz2+
involves: 129P2/OlaHsd * 129S/SvEv J:235399 View
systemic lupus erythematosus Atg7tm1Tchi/Atg7tm1Tchi
Lyz2tm1(cre)Ifo/Lyz2+
involves: 129P2/OlaHsd * C57BL/6NCrlj * CBA/JNCrlj J:235399 View
systemic lupus erythematosus Becn1tm1Ebr/Becn1tm1Ebr
Lyz2tm1(cre)Ifo/Lyz2+
involves: 129P2/OlaHsd J:235399 View
systemic lupus erythematosus C1qatm1Mjw/C1qatm1Mjw involves: 129P2/Ola * 129S/SvEv * C57BL/6 J:47315 View
systemic lupus erythematosus Cd19tm1(cre)Cgn/Cd19+
Ep300tm2Reck/Ep300+
involves: 129/Sv * 129P2/OlaHsd * C57BL/6 J:147840 View
systemic lupus erythematosus Cd79atm1(cre)Reth/Cd79a+
Inpp5dtm1Rav/Inpp5dtm1Rav
involves: 129 * BALB/c * C57BL/6 J:178833 View
systemic lupus erythematosus Cdkn1atm1Led/Cdkn1atm1Led involves: 129S6/SvEvTac J:76041 View
systemic lupus erythematosus Cdkn1atm1Led/Cdkn1atm1Led
Gadd45atm1Ajf/Gadd45atm1Ajf
either: (involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6) or (involves: 129S6/SvEvTac * 129X1/SvJ * C57BL/6) J:76041 View
systemic lupus erythematosus Cybbtm1Din/Cybbtm1Din B6.129S-Cybbtm1Din/J J:235399 View
systemic lupus erythematosus Def6Gt(OST307148)Lex/Def6Gt(OST307148)Lex involves: 129S5/SvEvBrd * C57BL/6 J:106469 View
systemic lupus erythematosus Fam210bem1Cya/Fam210bem1Cya involves: C57BL/6N J:351618 View
systemic lupus erythematosus Gadd45atm1Ajf/Gadd45atm1Ajf either: (involves: 129P2/OlaHsd * C57BL/6) or (involves: 129X1/SvJ * C57BL/6) J:76041 View
systemic lupus erythematosus Ifih1Rgsc422/Ifih1+ D2JJcl.B6JJcl-Ifih1Rgsc422 J:209917 View
systemic lupus erythematosus Ifih1Rgsc422/Ifih1Rgsc422 D2JJcl.B6JJcl-Ifih1Rgsc422 J:209917 View
systemic lupus erythematosus Ikzf3tm1Kge/Ikzf3tm1Kge involves: 129S4/SvJae * C57BL/6 J:50626, J:81805 View
systemic lupus erythematosus Jak1M1Mhda/Jak1+ C3HeB/FeJ-Jak1M1Mhda J:199153 View
systemic lupus erythematosus Junbtm3Wag/Junbtm3Wag
Tg(KRT5-cre)1Tak/0
involves: 129/Sv * 129P2/OlaHsd * C3H * C57BL/6 J:155575 View
systemic lupus erythematosus KitW-sh/KitW-sh
Lyntm1Ard/Lyntm1Ard
involves: 101 * 129P2/OlaHsd * C3H/HeH J:161523 View
systemic lupus erythematosus Lbric-J/Lbr+ (NZW/LacJ x C57BL/6J-Lbric-J/J)F1 J:234168 View
systemic lupus erythematosus Lyntm1Ard/Lyntm1Ard involves: 129P2/OlaHsd J:161523 View
systemic lupus erythematosus Man2a1tm1Jxm/Man2a1tm1Jxm involves: 129S1/Sv * 129X1/SvJ * C57BL/6 J:74579 View
systemic lupus erythematosus Mta2tm1.1Yzha/Mta2tm1.1Yzha involves: 129S4/SvJae * C57BL/6 * FVB/N J:137101 View
systemic lupus erythematosus Pld4thss/Pld4thss BALB/cJ-Pld4thss/GrsrJ J:278304 View
systemic lupus erythematosus Polbtm1.1Jbsw/Polbtm1.1Jbsw involves: 129/Sv * C57BL/6 J:206872 View
systemic lupus erythematosus Ppargtm1.1Gonz/Ppargtm1.1Gonz
Lyz2tm1(cre)Ifo/Lyz2+
involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6 J:168799 View
systemic lupus erythematosus Prdm1tm1Clme/Prdm1tm1Clme
Tg(Itgax-cre)1-1Reiz/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA J:178876 View
systemic lupus erythematosus Ptpn22tm2Achn/Ptpn22tm2Achn
Ptprctm1Weis/Ptprctm1Weis
B6.Cg-Ptprctm1Weis Ptpn22tm2Achn J:147129 View
systemic lupus erythematosus Ptprctm1Weis/Ptprc+ involves: 129X1/SvJ * C57BL/6 J:66501 View
systemic lupus erythematosus Ptprctm1Weis/Ptprctm1Weis involves: 129X1/SvJ * C57BL/6 J:66501 View
systemic lupus erythematosus Rasgrp1lag/Rasgrp1lag involves: 129 * C57BL/6 J:85189 View
systemic lupus erythematosus Rassf5tm1Kina/Rassf5tm1Kina B6.Cg-Rassf5tm1Kina J:168749 View
systemic lupus erythematosus Rc3h1san/Rc3h1san either: C57BL/6JSfdAnu-Rc3h1san/Anu or (involves: C57BL/6JSfdAnu * CBA/Ca) J:98938 View
systemic lupus erythematosus Ro60tm1Woln/Ro60+ involves: 129S1/Sv * C57BL/6 J:84627 View
systemic lupus erythematosus Ro60tm1Woln/Ro60tm1Woln B6.129S1-Ro60tm1Woln J:84627 View
systemic lupus erythematosus Ro60tm1Woln/Ro60tm1Woln involves: 129S1/Sv * C57BL/6 J:84627 View
systemic lupus erythematosus Rubcnem1Dgre/Rubcnem1Dgre involves: C57BL/6 * C57BL/6N J:235399 View
systemic lupus erythematosus Rxratm1Krc/Rxratm1Krc
Lyz2tm1(cre)Ifo/Lyz2+
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 J:168799 View
systemic lupus erythematosus Tg(Igh-V-CD40lg)#Tsub/0 C57BL/6-Tg(Igh-V-CD40lg)#Tsub J:128824 View
systemic lupus erythematosus Tg(Tlr7)1Boll/0 involves: C57BL/6 J:193610 View
systemic lupus erythematosus Timd4tm1Kuch/Timd4tm1Kuch involves: C57BL/6 J:235399 View
systemic lupus erythematosus Tlr7em2Anu/Tlr7+ C57BL/6NCrl-Tlr7em2Anu J:324448 View
systemic lupus erythematosus Tlr7em2Anu/Tlr7em2Anu C57BL/6NCrl-Tlr7em2Anu J:324448 View
systemic lupus erythematosus Tlr7em2Anu/Y C57BL/6NCrl-Tlr7em2Anu J:324448 View
systemic lupus erythematosus Tnfrsf13btm1Vmd/Tnfrsf13btm1Vmd involves: C57BL/6 J:82331 View
systemic lupus erythematosus Traf3ip2tm1.1Lix/Traf3ip2tm1.1Lix B6.129-Traf3ip2tm1.1Lix J:187766 View
Transgenes and
Other Mutations
     psoriasis Tg(CAG-Lyn*)#Paau/0 B6.Cg-Tg(CAG-Lyn*)#Paau J:151886 View
psoriasis Tg(CYP1A1-PPARD)#Jfoe/0 involves: C57BL/6J * CBA J:158907 View
psoriasis Tg(ITGA2)1067Fmw/0
Tg(ITGB1)0840Fmw/0
involves: C57BL/10 * CBA J:30249 View
psoriasis Tg(ITGA2)1067Fmw/0
Tg(ITGB1)0869Fmw/0
involves: C57BL/10 * CBA J:30249 View
psoriasis Tg(ITGA2)1067Fmw/0
Tg(ITGB1)0870Fmw/0
involves: C57BL/10 * CBA J:30249 View
psoriasis Tg(ITGA2)1070Fmw/0
Tg(ITGB1)0840Fmw/0
involves: C57BL/10 * CBA J:30249 View
psoriasis Tg(ITGA2)1070Fmw/0
Tg(ITGB1)0869Fmw/0
involves: C57BL/10 * CBA J:30249 View
psoriasis Tg(ITGA2)1070Fmw/0
Tg(ITGB1)0870Fmw/0
involves: C57BL/10 * CBA J:30249 View
psoriasis Tg(ITGA2)1075Fmw/0
Tg(ITGB1)0840Fmw/0
involves: C57BL/10 * CBA J:30249 View
psoriasis Tg(ITGA2)1075Fmw/0
Tg(ITGB1)0869Fmw/0
involves: C57BL/10 * CBA J:30249 View
psoriasis Tg(ITGA2)1075Fmw/0
Tg(ITGB1)0870Fmw/0
involves: C57BL/10 * CBA J:30249 View
psoriasis Tg(ITGA5)0794Fmw/0
Tg(ITGB1)0840Fmw/0
involves: C57BL/10 * CBA J:30249 View
psoriasis Tg(ITGA5)0794Fmw/0
Tg(ITGB1)0869Fmw/0
involves: C57BL/10 * CBA J:30249 View
psoriasis Tg(ITGA5)0794Fmw/0
Tg(ITGB1)0870Fmw/0
involves: C57BL/10 * CBA J:30249 View
psoriasis Tg(ITGA5)0844Fmw/0
Tg(ITGB1)0840Fmw/0
involves: C57BL/10 * CBA J:30249 View
psoriasis Tg(ITGA5)0844Fmw/0
Tg(ITGB1)0869Fmw/0
involves: C57BL/10 * CBA J:30249 View
psoriasis Tg(ITGA5)0844Fmw/0
Tg(ITGB1)0870Fmw/0
involves: C57BL/10 * CBA J:30249 View
psoriasis Tg(ITGA5)0858Fmw/0
Tg(ITGB1)0840Fmw/0
involves: C57BL/10 * CBA J:30249 View
psoriasis Tg(ITGA5)0858Fmw/0
Tg(ITGB1)0869Fmw/0
involves: C57BL/10 * CBA J:30249 View
psoriasis Tg(ITGA5)0858Fmw/0
Tg(ITGB1)0870Fmw/0
involves: C57BL/10 * CBA J:30249 View
psoriasis Tg(ITGB1)0840Fmw/0 involves: C57BL/10 * CBA J:30249 View
psoriasis Tg(ITGB1)0869Fmw/0 involves: C57BL/10 * CBA J:30249 View
psoriasis Tg(ITGB1)0870Fmw/0 involves: C57BL/10 * CBA J:30249 View
psoriasis Tg(KRT5-TGFB1)F2020Xjw/0 involves: C57BL/6 * DBA/2 * ICR J:90118 View
psoriasis Tg(KRT5-tTA)1216Glk/0
Tg(tetO-Tek)1Dmt/0
involves: CD-1 * FVB/N J:147438 View
psoriasis Tg(Krt14-Rac1*G12V)#Mrnk/0 either: B6.CBACa-Tg(Krt14-Rac1*G12V)#Mrnk or C.CBACa-Tg(Krt14-Rac1*G12V)#Mrnk J:237134 View
psoriasis Tg(Krt14-Rac1*G12V)#Mrnk/0 involves: CBA/CaJ J:237134 View
psoriasis Tg(Tek-tTA)1Dmt/0
Tg(tetO-Tek)1Dmt/0
involves: CD-1 J:96718 View
rheumatoid arthritis H2b/H2g7
Tg(TcraR28,TcrbR28)KRNDim/0
involves: C57BL/6 * NOD * SJL J:36815 View
rheumatoid arthritis Tg(CAG-SYVN1)1Tn/? D1.Cg-Tg(CAG-SYVN1)1Tn J:86009 View
rheumatoid arthritis Tg(FCGR2A)11Mkz/Tg(FCGR2A)11Mkz involves: C57BL/6 * SJL J:136516 View
rheumatoid arthritis Tg(HLA-DRA*0101,HLA-DRB1*0101)1Dmz/Tg(HLA-DRA*0101,HLA-DRB1*0101)1Dmz involves: C57BL/6 * C57BL/10Sn * SJL/J J:108635 View
rheumatoid arthritis Tg(TcraR28,TcrbR28)KRNDim/0 involves: C57BL/6 * NOD * SJL J:36815 View
rheumatoid arthritis Tg(TNF)197Gkl/0 involves: C57BL/6 * CBA J:92576 View
rheumatoid arthritis Tg(TNF)3647Gkl/0 involves: C57BL/6 * CBA J:190204 View
systemic lupus erythematosus Cd4tm1Mak/Cd4tm1Mak
Igh-Jtm2(3H9-VDJ*)Mwg/Igh-J+
B6.Cg-Cd4tm1Mak Igh-Jtm2(3H9-VDJ*)Mwg J:142389 View
systemic lupus erythematosus Igh-Jtm2(3H9-VDJ*)Mwg/Igh-J+ B6.129P2-Igh-Jtm2(3H9-VDJ*)Mwg J:142389 View
systemic lupus erythematosus Tcrbtm1Mom/Tcrbtm1Mom
Tcrdtm1Mom/Tcrdtm1Mom
Igh-Jtm2(3H9-VDJ*)Mwg/Igh-J+
B6.129P2-Tcrbtm1Mom Igh-Jtm2(3H9-VDJ*)Mwg Tcrdtm1Mom J:142389 View
systemic lupus erythematosus Tg(ACTB-TNFRSF6B)754Jwu/? B6.Cg-Tg(Actb-TNFRSF6B)754Jwu J:148162 View
systemic lupus erythematosus X/Yaa (NZB x BXSB)F1 J:6235 View
systemic lupus erythematosus X/Yaa (NZW x BXSB)F1 J:7276 View
systemic lupus erythematosus X/Yaa (NZW x SB)F1 J:7276 View
systemic lupus erythematosus X/Yaa BXSB/MpJ J:6235, J:108760, J:7308 View
systemic lupus erythematosus X/Yaa BXSB/MpJScr J:10973 View
Additional
Complex
Models
     bullous pemphigoid Col17a1tm1.1(COL17A1)Zliu/Col17a1tm1.1(COL17A1)Zliu involves: 129P2/OlaHsd * C57BL/6J J:261781 View
psoriasis Juntm4Wag/Juntm4Wag
Junbtm3Wag/Junbtm3Wag
Tg(Krt1-5-cre/ERT)1Ipc/0
involves: 129P2/OlaHsd * C57BL/6 * SJL J:116380 View
rheumatoid arthritis H2q/?
Ncf1m1J/Ncf1m1J
B6.Cg-Ncf1m1J H2q J:92437 View
systemic lupus erythematosus Apoetm1Unc/Apoetm1Unc
Faslgld/Faslgld
B6.Cg-Faslgld Apoetm1Unc J:91058, J:200141 View
systemic lupus erythematosus Csf2tm1Dran/Csf2tm1Dran
Il3tm1Glli/Il3tm1Glli
B6.129S2-Csf2tm1Dran Il3tm1Glli J:83086 View
systemic lupus erythematosus Ightm1.1(Igh564)Tik/Ightm1.1(Igh564)Tik
Igktm1(Igk564)Tik/Igktm1(Igk564)Tik
B6.129S4-Igktm1(Igk564)Tik Ightm1(Igh564)Tik J:113555 View
systemic lupus erythematosus Psen1tm1Bdes/Psen1+
Psen2tm1Bdes/Psen2tm1Bdes
involves: 129P2/OlaHsd J:91235 View


       
No similarity to the expected human disease phenotype was found.
        Disease Term Allelic Composition Genetic Background Reference Phenotypes
NOT Models      Hailey-Hailey disease Atp2c1tm1Ges/Atp2c1+ involves: 129X1/SvJ * Black Swiss J:124662 View
psoriasis Itgb2tm1Bay/Itgb2tm2Bay B6.129S7-Itgb2tm1Bay Itgb2tm2Bay J:84126 View
rheumatoid arthritis Ighmtm1Cgn/Ighmtm1Cgn
Tg(TcraR28,TcrbR28)KRNDim/0
involves: 129S2/SvPas * C57BL/6 * NOD * SJL J:36815 View
systemic lupus erythematosus Csf2tm1Dran/Csf2tm1Dran
Ifngtm1Ts/Ifngtm1Ts
Il3tm1Glli/Il3tm1Glli
involves: 129S2/SvPas * 129S7/SvEvBrd * C57BL/6 J:83086 View
systemic lupus erythematosus Tlr7tm1Flv/Y
X/Yaa
B6.Cg-Tlr7tm1Flv Yaa J:127600 View